Genetic variation in Mycobacterium tuberculosis isolates from a London outbreak associated with isoniazid resistance

BMC Medicine

Volumn 14, Issue 1, 2016, Pages

  Satta, Giovanni ^a,b   Witney, Adam A ^c   Shorten, Robert J ^a,d   Karlikowska, Magdalena ^a   Lipman, Marc ^e,f   McHugh, Timothy D ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^c ST GEORGE S HOSPITAL   (United Kingdom)

^d MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^e ROYAL FREE LONDON NHS FOUNDATION TRUST   (United Kingdom)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Fitness; Mutation rate; Mycobacterium tuberculosis; Whole genome sequencing

Indexed keywords

ISONIAZID; TUBERCULOSTATIC AGENT;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; ENGLAND; EPIDEMIC; GENE DELETION; GENETIC PROCEDURES; GENETIC VARIATION; MUTATION RATE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE GENOME SEQUENCING; DRUG EFFECTS; EUROPE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANT TUBERCULOSIS; MUTATION; PROCEDURES; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DISEASE OUTBREAKS; DRUG RESISTANCE, BACTERIAL; EUROPE; GENETIC VARIATION; HUMANS; ISONIAZID; LONDON; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; TUBERCULOSIS; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 84982094943     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-016-0659-6     Document Type: Article

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