Acclimation training improves endurance cycling performance in the heat without inducing endotoxemia

Frontiers in Physiology

Volumn 7, Issue JUL, 2016, Pages

  Guy, Joshua H ^a,b   Pyne, David B ^a,c   Deakin, Glen B ^a   Miller, Catherine M ^a   Edwards, Andrew M ^a,b  

^a JAMES COOK UNIVERSITY   (Australia)

^b PLYMOUTH MARJON UNIVERSITY   (United Kingdom)

^c AUSTRALIAN INSTITUTE OF SPORT   (Australia)

Author keywords

Cycling; Cytokine; Endurance performance; Heat acclimation; Inflammation; Lipopolysacharide

Indexed keywords

IMMUNOGLOBULIN M; INTERLEUKIN 6; LIPOPOLYSACCHARIDE;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CORE TEMPERATURE; CYCLING; ENDURANCE TRAINING; HEART RATE; HEAT STRESS; HEAT TOLERANCE; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; MALE; PHYSICAL CAPACITY; PHYSICAL PERFORMANCE; TEMPERATURE ACCLIMATIZATION; TEMPERATURE SENSITIVITY; YOUNG ADULT;

EID: 84981525058     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2016.00318     Document Type: Article

References (29)

1. Abbasi, A., Fehrenbach, E., Hauth, M., Walter, M., Hudemann, J., Wank, V., et al. (2013). Changes in spontaneous and LPS-induced ex vivo cytokine production and mRNA expression in male and female athletes following prolonged exhaustive exercise. Exerc. Immunol. Rev. 19, 8-28.
2. Borg, G. (1970). Perceived exertion as an indicator of somatic stress. Scand. J. Rehabil. Med. 2, 92-98.
3. Bouchama, A., Kwaasi, A., Dehbi, M., Al Mohanna, F., Eldali, A., El-Sayed, R., et al. (2007). Glucocorticoids do not protect against the lethal effects of experimental heatstroke in baboons. Shock 27, 578-583. doi: 10.1097/01.shk.0000246903.40142.aa
4. Camus, G., Nys, M., Poortmans, J. R., Venneman, I., Monfils, T., Deby-Dupont, G., et al. (1998). Endotoxaemia, production of tumour necrosis factor alpha and polymorphonuclear neutrophil activation following strenuous exercise in humans. Eur. J. Appl. Physiol. 79, 62-68.
5. Chalmers, S., Esterman, A., Eston, R., Bowering, K. J., and Norton, K. (2014). Short-term heat acclimation training improves physical performance: a systematic review, and exploration of physiological adaptations and application for team sports. Sports Med. 44, 971-988. doi: 10.1007/s40279-014-0178-6
6. Daanen, H. A. M., Jonkman, A. G., Layden, J. D., Linnane, D. M., and Weller, A. S. (2011). Optimising the acquisition and retention of heat acclimation. Int. J. Sports Med. 32, 822-828. doi: 10.1055/s-0031-1279767
7. Dawson, B., Pyke, F. S., and Morton, A. R. (1989). Improvements in heat tolerance induced by interval running training in the heat and in sweat clothing in cool conditions. J. Sports Sci. 7, 189-203. doi: 10.1080/02640418908729840
8. Garrett, A. T., Creasy, R., Rehrer, N. J., Patterson, M. J., and Cotter, J. D. (2012). Effectiveness of short-term heat acclimation for highly trained athletes. Eur. J. Appl. Physiol. 112, 1827-1837. doi: 10.1007/s00421-011-2153-3
9. Garrett, A. T., Goosens, N. G., Rehrer, N. G., Patterson, M. J., and Cotter, J. D. (2009). Induction and decay of short-term heat acclimation. Eur. J. Appl. Physiol. 107, 659-670. doi: 10.1007/s00421-009-1182-7
10. Garrett, A. T., Rehrer, N. J., and Patterson, M. J. (2011). Induction and decay of short-term heat acclimation in moderately and highly trained athletes. Sports Med. 41, 757-771. doi: 10.2165/11587320-000000000-00000
11. Gibson, O. R., Mee, J. A., Taylor, L., Tuttle, J. A., Watt, P. W., and Maxwell, N. S. (2015). Isothermic and fixed-intensity heat acclimation methods elicit equal increases in Hsp72 mRNA. Scand. J. Med. Sci. Sport 25, 259-268. doi: 10.1111/sms.12430
12. Gill, S. K., Teixeira, A., Rama, L., Prestes, J., Rosado, F., Hankey, J., et al. (2014). Circulatory endotoxin concentration and cytokine profile in response to exertional-heat stress during a multi-stage ultra-marathon competition. Exerc. Immunol. Rev. 21, 114-128.
13. Gleeson, M. (1998). Temperature regulation during exercise. Int. J. Sports Med. 19, S96-S99. doi: 10.1055/s-2007-971967
14. Guy, J. H., Deakin, G. B., Edwards, A. M., Miller, C. M., and Pyne, D. B. (2015). Adaptation to hot environmental conditions: an exploration of the performance basis, procedures and future directions to optimise opportunities for elite athletes. Sports Med. 45, 303-311. doi: 10.1007/s40279-014-0277-4
15. Hailes, W. S., Slivka, D., Cuddy, J., and Ruby, B. C. (2011). Human plasma inflammatory response during 5 days of exercise training in the heat. J. Therm. Biol. 36, 277-282. doi: 10.1016/j.jtherbio.2011.03.013
16. Hopkins, W. G. (2004). How to interpret changes in an athletic performance test. Sportscience 8, 1-7. Available online at: http://www.sportsci.org/jour/04/wghtests.pdf
17. Kelly, M., Gastin, P. B., Dwyer, D. B., Sostaric, S., and Snow, R. J. (2016). Short duration heat acclimation in Australian football players. J. Sports Sci. Med. 15, 118.
18. Lim, C. L., Pyne, D., Horn, P., Kalz, A., Saunders, P., Peake, J., et al. (2009). The effects of increased endurance training load on biomarkers of heat intolerance during intense exercise in the heat. Appl. Physiol. Nutr. Metab. 34, 616-624. doi: 10.1139/H09-021
19. Lorenzo, S., Halliwill, J. R., Sawka, M. N., and Minson, C. T. (2010). Heat acclimation improves exercise performance. J. Appl. Physiol. 109, 1140-1147. doi: 10.1152/japplphysiol.00495.2010
20. Midgley, A. W., McNaughton, L. R., Polman, R., and Marchant, D. (2007). Criteria for determination of maximal oxygen uptake. Sports Med. 37, 1019-1028. doi: 10.2165/00007256-200737120-00002
21. Moldoveanu, A. I., Shephard, R. J., and Shek, P. N. (2000). Exercise elevates plasma levels but not gene expression of IL-1ß, IL-6, and TNF-a in blood mononuclear cells. J. Appl. Physiol. 89, 1499-1504.
22. Natelson, B. H., Zhou, X., Ottenweller, J. E., Bergen, M. T., Sisto, S. A., Drastal, S., et al. (1996). Effect of acute exhausting exercise on cytokine gene expression in men. Int. J. Sports Med. 17, 299-302. doi: 10.1055/s-2007-972850
23. Nielsen, B., Strange, S., Christensen, N. J., Warberg, J., and Saltin, B. (1997). Acute and adaptive responses in humans to exercise in a warm, humid environment. Pflügers Arch. 434, 49-56. doi: 10.1007/s004240050361
24. Périard, J. D., Racinais, S., and Sawka, M. N. (2015). Adaptations and mechanisms of human heat acclimation: applications for competitive athletes and sports. Scand. J. Med. Sci. Sport 25, 20-38. doi: 10.1111/sms.12408
25. Pyne, D. B., Guy, J. H., and Edwards, A. M. (2014). Managing heat and immune stress in athletes with evidence-based strategies. Int. J. Sports Physiol. Perform. 9, 744-750. doi: 10.1123/ijspp.2014-0232
26. Selkirk, G. A., McLellan, T. M., Wright, H. E., and Rhind, S. G. (2008). Mild endotoxemia, NF-?B translocation, and cytokine increase during exertional heat stress in trained and untrained individuals. Am. J. Physiol. Regul. Integr. Compr. Physiol. 295, R611-R623. doi: 10.1152/ajpregu.00917.2007
27. Vargas, N. T., and Marino, F. (2014). A neuroinflammatory model for acute fatigue during exercise. Sports Med. 44, 1479-1487. doi: 10.1007/s40279-014-0232-4
28. Wingfield, G. L., Gale, R., Minett, G. M., Marino, F. E., and Skein, M. (2016). The effect of high versus low intensity heat acclimation on performance and neuromuscular responses. J. Therm. Biol. 58, 50-59. doi: 10.1016/j.jtherbio.2016.02.006
29. Yeh, Y. J., Law, L. Y., and Lim, C. L. (2013). Gastrointestinal response and endotoxemia during intense exercise in hot and cool environments. Eur. J. Appl. Physiol. 113, 575-1583. doi: 10.1007/s00421-013-2587-x