Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study

Journal of Alzheimer's Disease

Volumn 53, Issue 3, 2016, Pages 1069-1078

  Marseglia, Anna ^a   Fratiglioni, Laura ^a,b   Laukka, Erika J ^a   Santoni, Giola ^a   Pedersen, Nancy L ^a   Bäckman, Lars ^a   Xu, Weili ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b STOCKHOLM GERONTOLOGY RESEARCH CENTER   (Sweden)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Apolipoprotein E4; cognition; type 2 diabetes mellitus; vascular disorders

Indexed keywords

APOLIPOPROTEIN E;

AGE DISTRIBUTION; AGED; ARTICLE; ATTENTION; BRAIN FUNCTION; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; COGNITIVE DEFECT; DEPRESSION; DIABETES MELLITUS; EDUCATIONAL STATUS; EPISODIC MEMORY; FEMALE; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HEART DISEASE; HUMAN; HYPERTENSION; IMPAIRED GLUCOSE TOLERANCE; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PERCEPTION; PERFORMANCE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SEMANTIC MEMORY; SEX DIFFERENCE; SMOKING; VELOCITY; WORKING MEMORY; COMPLICATION; FOLLOW UP; GENETICS; HEALTH CARE PLANNING; MENTAL HEALTH; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; STATISTICAL MODEL; VERY ELDERLY;

AGED; AGED, 80 AND OVER; APOLIPOPROTEINS E; COGNITION DISORDERS; COMMUNITY HEALTH PLANNING; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; HUMANS; LOGISTIC MODELS; MALE; MENTAL STATUS SCHEDULE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS;

EID: 84981357159     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-160266     Document Type: Article

References (40)

1. Biessels GJ, Strachan MW, Visseren FL, Kappelle LJ, Whitmer RA (2014) Dementia and cognitive decline in type 2 diabetes and prediabetic stages: Towards targeted interventions. Lancet Diabetes Endocrinol 2, 246-255.
2. Palta P, Schneider AL, Biessels GJ, Touradji P, Hill-Briggs F (2014) Magnitude of cognitive dysfunction in adults with type 2 diabetes: A meta-analysis of six cognitive domains and the most frequently reported neuropsychological tests within domains. J Int Neuropsychol Soc 20, 278-291.
3. Reijmer YD, Brundel M, de Bresser J, Kappelle LJ, Leemans A, Biessels GJ (2013) Microstructural white matter abnormalities and cognitive functioning in type 2 diabetes: A diffusion tensor imaging study. Diabetes Care 36, 137-144.
4. Yeung SE, Fischer AL, Dixon RA (2009) Exploring effects of type 2 diabetes on cognitive functioning in older adults. Neuropsychology 23, 1-9.
5. Ravona-Springer R, Heymann A, Schmeidler J, Sano M, Preiss R, Koifman K, Hoffman H, Silverman JM, Beeri MS (2014) The ApoE4 genotype modifies the relationship of long-term glycemic control with cognitive functioning in elderly with type 2 diabetes. Eur Neuropsychopharmacol 24, 1303-1308.
6. Rydwik E,Welmer AK,Kareholt I, Angleman S, Fratiglioni L,Wang HX (2013) Adherence to physical exercise recommendations in people over 65: The SNAC-Kungsholmen study. Eur J Public Health 23, 799-804.
7. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, JonesDW,Materson BJ, Oparil S, Wright JT Jr, Roccella EJ, National Heart, Lung, and Blood Institute Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, National High Blood Pressure Education Program Coordinating Committee (2003) The seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure: The JNC 7 report. JAMA 289, 2560-2572.
8. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, Lackland DT, LeFevre ML, MacKenzie TD, Ogedegbe O, SmithSCJr, SvetkeyLP,Taler SJ, Townsend RR, Wright JT Jr, Narva AS, Ortiz E (2014) 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 311, 507-520.
9. Pantzar A, Laukka EJ, Atti AR, Fastbom J, Fratiglioni L, Bäckman L (2014) Cognitive deficits in unipolar old-age depression:Apopulation-based study. PsycholMed44, 937-947.
10. Goodall I (2005) HbA1c standardisation destination-global IFCC Standardisation. How, why, where and when-a tortuous pathway from kit manufacturers, via inter-laboratory lyophilized and whole blood comparisons to designated national comparison schemes. Clin Biochem Rev 26, 5-19.
11. American Diabetes Association (2013) Diagnosis and classification of diabetes mellitus. Diabetes Care 36, S67-S74.
12. Xu WL, Pedersen NL, Keller L, Kalpouzos G, Wang HX, Graff C, Winblad B, Bäckman L, Fratiglioni L (2015) HHEX 23 AA genotype exacerbates effect of diabetes on dementia and Alzheimer disease: A population-based longitudinal study. PLoS Med 12, e1001853.
13. De Ronchi D, Berardi D, Menchetti M, Ferrari G, Serretti A, Dalmonte E, Fratiglioni L (2005) Occurrence of cognitive impairment and dementia after the age of 60: A populationbased study from Northern Italy. Dement Geriatr Cogn Disord 19, 97-105.
14. Magni E, Binetti G, Bianchetti A, Rozzini R, Trabucchi M (1996) Mini-Mental State Examination: A normative study in Italian elderly population. Eur J Neurol 3, 198-202.
15. Caracciolo B, Palmer K, Monastero R,Winblad B, Backman L, Fratiglioni L (2008) Occurrence of cognitive impairment and dementia in the community: A 9-year-long prospective study. Neurology 70, 1778-1785.
16. Laukka EJ, Lövdén M, Herlitz A, Karlsson S, Ferencz B, Pantzar A, Keller L, Graff C, Fratiglioni L, Bäckman L (2013) Genetic effects on old-age cognitive functioning: A population-based study. Psychol Aging 28, 262-274.
17. Lezack M, Howieson DB, Bigler ED, Tranel D (2012) Neuropsychological assessment, 5th ed. Oxford University Press, New York.
18. Rizzuto D, Orsini N, Qiu C,Wang HX, Fratiglioni L (2012) Lifestyle, social factors, and survival after age 75: Population based study. BMJ 345, e5568.
19. Xu WL, Qiu CX,Wahlin A,Winblad B, Fratiglioni L (2004) Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study. Neurology 63, 1181-1186.
20. van den Berg E, Reijmer YD, de Bresser J, Kessels RP, Kappelle LJ, Biessels GJ (2010) A 4 year follow-up study of cognitive functioning in patients with type 2 diabetes mellitus. Diabetologia 53, 58-65.
21. Takeuchi A, Matsushima E, Kato M,Konishi M, Izumiyama H, Murata Y, Hirata Y (2012) Characteristics of neuropsychological functions in inpatients with poorly-controlled type 2 diabetes mellitus. J Diabetes Investig 3, 325-330.
22. Maggi S, Limongi F, Noale M, Romanato G, Tonin P, Rozzini R, Scafato E, Crepaldi G, ILSA Study Group (2009) Diabetes as a risk factor for cognitive decline in older patients. Dement Geriatr Cogn Disord 27, 24-33.
23. Petersen RC, Caracciolo B, Brayne C, Gauthier S, Jelic V, Fratiglioni L (2014) Mild cognitive impairment: A concept in evolution. J Intern Med 275, 214-228.
24. Gao L, Matthews FE, Sargeant LA, Brayne C (2008) An investigation of the population impact of variation in HbA1c levels in older people in England and Wales: From a population based multi-centre longitudinal study. BMC Public Health 8, 54.
25. Shorr RI, de Rekeneire N, Resnick HE, Yaffe K, Somes GW, Kanaya AM, Simonsick EM, Newman AB, Harris TB (2006) Glycemia and cognitive function in older adults using glucose-lowering drugs. J Nutr Health Aging 10, 297-301.
26. Bergman I, Almkvist O (2013) The effect of age on fluid intelligence is fully mediated by physical health. Arch Gerontol Geriatr 57, 100-109.
27. Reijmer YD, Leemans A, Brundel M, Kappelle LJ, Biessels GJ (2013) Disruption of the cerebral white matter network is related to slowing of information processing speed in patients with type 2 diabetes. Diabetes 62, 2112-2115.
28. Wang R, Fratiglioni L, Laukka EJ, Lövdén M, Kalpouzos G, Keller L, Graff C, Salami A, Bäckman L, Qiu C (2015) Effects of vascular risk factors andAPOE-4 on white matter integrity and cognitive decline. Neurology 84, 1128-1135.
29. He XS,Wang ZX, Zhu YZ,Wang N, Hu X, Zhang DR, Zhu DF, Zhou JN (2015) Hyperactivation of working memoryrelated brain circuits in newly diagnosed middle-aged type 2 diabetics. Acta Diabetol 52, 133-142.
30. Hester RL, Kinsella GJ, Ong B (2004) Effect of age on forward and backward span tasks. J Int Neuropsychol Soc 10, 475-481.
31. Ghasemi R, Haeri A, Dargahi L, Mohamed Z, Ahmadiani A (2012) Insulin in the brain: Sources, localization and functions. Mol Neurobiol 47, 145-171.
32. Craft S, Cholerton B, Baker LD (2013) Insulin and Alzheimer's disease: Untangling the web. J Alzheimers Dis 33(Suppl 1), S263-S275.
33. Rochette L, Zeller M, Cottin Y, Vergely C (2014) Diabetes, oxidative stress and therapeutic strategies. Biochim Biophys Acta 1840, 2709-2729.
34. Huber JD, VanGilder RL, Houser KA (2006) Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats. Am J Physiol Heart Circ Physiol 291, H2660-H2668.
35. Thorpe CT, Gelland WF, Good CB, Zhang A, Zhao X, Mor M, Fine MJ (2015) Tight glycemic control and use of hypoglycemic medications in older veterans with type 2 diabetes and comorbid dementia. Diabetes Care 38, 588-595.
36. Koekkoek PS, Kappelle LJ, van den Berg E, Rutten GE, Biessels GJ (2015). Cognitive function in patients with diabetes mellitus: Guidance for daily care. Lancet Neurol 14, 329-340.
37. XuW, Qiu C,Winblad B, Fratiglioni L (2007) The effect of borderline diabetes on the risk of dementia and Alzheimer's disease. Diabetes 56, 211-216.
38. Borenstein AR, Wu Y, Mortimer JA, Schellenberg GD, McCormick WC, Bowen JD, McCurry S, Larson EB (2005) Developmental and vascular risk factors for Alzheimer's disease. Neurobiol Aging 26, 325-334.
39. Wirth M, Villeneuve S, La Joie R, Marks SM, Jagust WJ (2014) Gene-environment interactions: Lifetime cognitive activity, APOE genotype, and beta-amyloid burden. J Neurosci 34, 8612-8617.
40. van 't Riet E, Alssema M, Rijkelijkhuizen JM, Kostense PJ, Nijpels G, Dekker JM (2010) Relationship between A1C and glucose levels in the general Dutch population: The new Hoorn study. Diabetes Care 33, 61-66.