Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation

Nature Immunology

Volumn 17, Issue 10, 2016, Pages 1216-1225

  Barwick, Benjamin G ^a   Scharer, Christopher D ^a   Bally, Alexander P R ^a   Boss, Jeremy M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; ORGANIC CATION TRANSPORTER 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR IRF; UNCLASSIFIED DRUG; INTERFERON REGULATORY FACTOR; OCTAMER TRANSCRIPTION FACTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL DIVISION; CONTROLLED STUDY; DEMETHYLATION; DNA METHYLATION; ENHANCER REGION; FEMALE; FLOW CYTOMETRY; GENE CONTROL; GENE EXPRESSION; IN VIVO STUDY; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PLASMA CELL; PLASMABLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; ANIMAL; BINDING SITE; C57BL MOUSE; CELL CULTURE; CPG ISLAND; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMORAL IMMUNITY; METABOLISM; PHYSIOLOGY;

ANIMALS; B-LYMPHOCYTES; BINDING SITES; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CPG ISLANDS; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; IMMUNITY, HUMORAL; INTERFERON REGULATORY FACTORS; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; OCTAMER TRANSCRIPTION FACTOR-2; PLASMA CELLS; TRANSCRIPTION FACTOR AP-1;

EID: 84981205620     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3519     Document Type: Article

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