Quantile regression analysis of the distributional effects of air pollution on blood pressure, heart rate variability, blood lipids, and biomarkers of inflammation in elderly american men: The Normative Aging Study

Environmental Health Perspectives

Volumn 124, Issue 8, 2016, Pages 1189-1198

  Bind, Marie Abele ^a   Peters, Annette ^b   Koutrakis, Petros ^c   Coull, Brent ^c   Vokonas, Pantel ^d   Schwartz, Joel ^c  

^a HARVARD UNIVERSITY   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLACK CARBON; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; AIR POLLUTANT; BIOLOGICAL MARKER;

ADULT; AGED; AIR POLLUTION; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR RISK; DIABETES MELLITUS; ELECTROCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART RATE VARIABILITY; HEART REPOLARIZATION; HEART RHYTHM; HUMAN; INFLAMMATION; MALE; NORMAL HUMAN; OBESITY; PARTICLE SIZE; PRIORITY JOURNAL; QT INTERVAL; REGRESSION ANALYSIS; SENSITIVITY ANALYSIS; SMOKING; TRAFFIC; AGING; AIR POLLUTANT; ANALYSIS; BLOOD; CARDIOVASCULAR DISEASES; CHEMICALLY INDUCED; ENVIRONMENTAL EXPOSURE; HEART RATE; MASSACHUSETTS; METABOLISM; MIDDLE AGED; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

AGED; AGING; AIR POLLUTANTS; AIR POLLUTION; BIOMARKERS; BLOOD PRESSURE; BOSTON; CARDIOVASCULAR DISEASES; ENVIRONMENTAL EXPOSURE; HEART RATE; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; LIPIDS; MALE; MIDDLE AGED; RISK FACTORS;

EID: 84980401144     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1510044     Document Type: Article

References (37)

1. Alexeeff SE, Schwartz J, Kloog I, Chudnovsky A, Koutrakis P, Coull BA. 2015. Consequences of kriging and land use regression for PM2.5 predictions in epidemiologic analyses: insights into spatial variability using high-resolution satellite data. J Expo Sci Environ Epidemiol 25(2):138-144, doi: 10.1038/jes.2014.40.
2. Amancio CT, Nascimento LF. 2014. Environmental pollution and deaths due to stroke in a city with low levels of air pollution: ecological time series study. Sao Paulo Med J 132(6):353-358, doi: 10.1590/1516-3180.2014.1326733.
3. Baja ES, Schwartz JD, Wellenius GA, Coull BA, Zanobetti A, Vokonas PS, et al. 2010. Traffic-related air pollution and QT interval: modification by diabetes, obesity, and oxidative stress gene polymorphisms in the Normative Aging Study. Environ Health Perspect 118:840-846, doi: 10.1289/ehp.0901396.
4. Bateson TF, Schwartz J. 2004. Who is sensitive to the effects of particulate air pollution on mortality? A case-crossover analysis of effect modifiers. Epidemiology 15(2):143-149.
5. Bednar MM, Harrigan EP, Anziano RJ, Camm AJ, Ruskin JN. 2001. The QT interval. Prog Cardiovasc Dis 43(5 suppl 1):1-45.
6. Bell B, Rose CL, Damon A. 1966. The Veterans Administration longitudinal study of healthy aging. Gerontologist 6(4):179-184.
7. Bind MA, Baccarelli A, Zanobetti A, Tarantini L, Suh H, Vokonas P, et al. 2012. Air pollution and markers of coagulation, inflammation, and endothelial function: associations and epigene-environment interactions in an elderly cohort. Epidemiology 23(2):332-340, doi: 10.1097/EDE.0b013e31824523f0.
8. Bind MA, Coull BA, Peters A, Baccarelli AA, Tarantini L, Cantone L, et al. 2015. Beyond the mean: quantile regression to explore the association of air pollution with gene-specific methylation in the Normative Aging Study. Environ Health Perspect 123:759-765, doi: 10.1289/ehp.1307824.
9. Breton CV, Salam MT, Vora H, Gauderman WJ, Gilliland FD. 2011. Genetic variation in the glutathione synthesis pathway, air pollution, and children’s lung function growth. Am J Respir Crit Care Med 183(2):243-248, doi: 10.1164/rccm.201006-0849OC.
10. Brook RD, Rajagopalan S, Pope CA, III, Brook JR, Bhatnagar A, Diez-Roux AV, et al. 2010. Particulate matter air pollution and cardio vascular disease: an update to the scientific statement from the American Heart Association. Circulation 121(21):2331-2378, doi: 10.1161/CIR.0b013e3181dbece1.
11. Devlin RB, Smith CB, Schmitt MT, Rappold AG, Hinderliter A, Graff D, et al. 2014. Controlled exposure of humans with metabolic syndrome to concentrated ultrafine ambient particulate matter causes cardiovascular effects. Toxicol Sci 140(1):61-72, doi: 10.1093/toxsci/kfu063.
12. Foraster M, Basagaña X, Aguilera I, Rivera M, Agis D, Bouso L, et al. 2014. Association of long-term exposure to traffic-related air pollution with blood pressure and hypertension in an adult population-based cohort in Spain (the REGICOR study). Environ Health Perspect 122:404-411, doi: 10.1289/ehp.1306497
13. Friedewald WT, Levy RI, Fredrickson DS. 1972. Estimation of the concentration of low-density lipo-protein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18(6):499-502.
14. Gong H Jr, Linn WS, Terrell SL, Clark KW, Geller MD, Anderson KR, et al. 2004. Altered heart-rate vari-ability in asthmatic and healthy volunteers exposed to concentrated ambient coarse particles. Inhal Toxicol 16(6-7):335-343, doi: 10.1080/08958370490439470.
15. Hampel R, Schneider A, Brüske I, Zareba W, Cyrys J, Rückerl R, et al. 2010. Altered cardiac repolarization in association with air pollution and air temperature among myocardial infarction survivors. Environ Health Perspect 118:1755-1761, doi: 10.1289/ehp.1001995.
16. Hicken MT, Adar SD, Diez Roux AV, O’Neill MS, Magzamen S, Auchincloss AH, et al. 2013. Do psychosocial stress and social disadvantage modify the association between air pollution and blood pressure? The Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol 178(10):1550-1562, doi: 10.1093/aje/kwt190.
17. Hoffmann B, Luttmann-Gibson H, Cohen A, Zanobetti A, de Souza C, Foley C, et al. 2012. Opposing effects of particle pollution, ozone, and ambient temperature on arterial blood pressure. Environ Health Perspect 120:241-246, doi: 10.1289/ehp.1103647.
18. Hu H, Aro A, Payton M, Korrick S, Sparrow D, Weiss ST, et al. 1996. The relationship of bone and blood lead to hypertension: the Normative Aging Study. JAMA 275(15):1171-1176.
19. Janssen NA, Hoek G, Brunekreef B, Harssema H, Mensink I, Zuidhof A. 1998. Personal sampling of particles in adults: relation among personal, indoor, and outdoor air concentrations. Am J Epidemiol 147(6):537-547.
20. Kang CM, Koutrakis P, Suh HH. 2010. Hourly measure-ments of fine particulate sulfate and carbon aerosols at the Harvard-U.S. Environmental Protection Agency Supersite in Boston. J Air Waste Manag Assoc 60(11):1327-1334.
21. Koenker R. 2004. Quantile regression for longitudinal data. J Multivar Anal 91(1):74-89.
22. Ljungman P, Bellander T, Schneider A, Breitner S, Forastiere F, Hampel R, et al. 2009. Modification of the interleukin-6 response to air pollution by inter-leukin-6 and fibrinogen polymorphisms. Environ Health Perspect 117:1373-1379, doi: 10.1289/ehp.0800370.
23. Madrigano J, Baccarelli A, Mittleman MA, Sparrow D, Spiro A, III, Vokonas PS, et al. 2012. Air pollution and DNA methylation: interaction by psychological factors in the VA Normative Aging Study. Am J Epidemiol 176(3):224-232, doi: 10.1093/aje/kwr523.
24. Mordukhovich I, Wilker E, Suh H, Wright R, Sparrow D, Vokonas PS, et al. 2009. Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study. Environ Health Perspect 117:1767-1772, doi: 10.1289/ehp.0900591.
25. Park SK, O’Neill MS, Wright RO, Hu H, Vokonas PS, Sparrow D, et al. 2006. HFE genotype, particu-late air pollution, and heart rate variability: a gene-environment interaction. Circulation 114(25):2798-2805, doi: 10.1161/CIRCULATIONAHA.106.643197.
26. Peters A, Perz S, Döring A, Stieber J, Koenig W, Wichmann HE. 1999. Increases in heart rate during an air pollution episode. Am J Epidemiol 150(10):1094-1098.
27. Peters A, Perz S, Döring A, Stieber J, Koenig W, Wichmann HE. 2000. Activation of the autonomic nervous system and blood coagulation in association with air pollution episode. Inhal Toxicol 12(suppl 2):51-61.
28. Ren C, Baccarelli A, Wilker E, Suh H, Sparrow D, Vokonas P, et al. 2010. Lipid and endothelium-related genes, ambient particulate matter, and heart rate variability—the VA Normative Aging Study. J Epidemiol Community Health 64(1):49-56, doi: 10.1136/jech.2008.083295.
29. Ren C, O’Neill MS, Park SK, Sparrow D, Vokonas P, Schwartz J. 2011. Ambient temperature, air pollution, and heart rate variability in an aging population. Am J Epidemiol 173(9):1013-1021, doi: 10.1093/aje/kwq477.
30. Ridker PM, MacFadyen J, Libby P, Glynn RJ. 2010. Relation of baseline high-sensitivity C-reactive protein level to cardiovascular outcomes with rosuvastatin in the Justification for Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER). Am J Cardiol 106(2):204-209, doi: 10.1016/j.amjcard.2010.03.018.
31. Rückerl R, Greven S, Ljungman P, Aalto P, Antoniades C, Bellander T, et al. 2007. Air pollution and inflammation (interleukin-6, C-reactive protein, fibrinogen) in myocardial infarction survivors. Environ Health Perspect 115:1072-1080, doi: 10.1289/ehp.10021.
32. Shumake KL, Sacks JD, Lee JS, Johns DO. 2013. Susceptibility of older adults to health effects induced by ambient air pollutants regulated by the European Union and the United States. Aging Clin Exp Res 25(1):3-8, doi: 10.1007/s40520-013-0001-5.
33. Tager IB, Künzli N, Ngo L, Balmes J. 1998. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part I: variability of pulmonary function measures. Res Rep Health Eff Inst 81:1-25.
34. Wilker EH, Baccarelli A, Suh H, Vokonas P, Wright RO, Schwartz J. 2010. Black carbon exposures, blood pressure and interactions with single nucleotide ploymorphisms in microRNA processing genes. Environ Health Perspect, doi: 10.1289/ehp.0901440.
35. Yang IA, Fong KM, Zimmerman PV, Holgate ST, Holloway JW. 2009. Genetic susceptibility to the respiratory effects of air pollution. Postgrad Med J 85(1006):428-436, doi: 10.1136/thx.2007.079426.
36. Zeger SL, Thomas D, Dominici F, Samet JM, Schwartz J, Dockery D, et al. 2000. Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environ Health Perspect 108:419-426.
37. Zeka A, Sullivan JR, Vokonas PS, Sparrow D, Schwartz J. 2006. Inflammatory markers and particulate air pollution: characterizing the pathway to disease. Int J Epidemiol 35(5):1347-1354, doi: 10.1093/ije/dyl132.