메뉴 건너뛰기




Volumn 2, Issue 2, 2015, Pages

Two distinct hepatitis C virus genotype 1a clades have different geographical distribution and association with natural resistance to NS3 protease inhibitors

(20)  De Luca, Andrea a,b   Di Giambenedetto, Simona b   Lo Presti, Alessandra c   Sierra, Saleta d   Prosperi, Mattia e   Cella, Eleonora c,f   Giovanetti, Marta c,g   Torti, Carlo h,i   Caudai, Cinzia j   Vicenti, Ilaria j   Saladini, Francesco j   Almi, Paolo a   Grima, Pierfrancesco k   Blanc, Pierluigi l   Fabbiani, Massimiliano b   Rossetti, Barbara a   Gagliardini, Roberta b   Kaiser, Rolf d   Ciccozzi, Massimo c,m   Zazzi, Maurizio j  


Author keywords

Drug resistance; Genotype 1a; HCV; Protease; Q80K

Indexed keywords

HEPACIVIRIN INHIBITOR; NONSTRUCTURAL PROTEIN 3; SIMEPREVIR; SOFOSBUVIR;

EID: 84979964663     PISSN: None     EISSN: 23288957     Source Type: Journal    
DOI: 10.1093/ofid/ofv043     Document Type: Article
Times cited : (34)

References (48)
  • 1
    • 78751621217 scopus 로고    scopus 로고
    • Evolving epidemiology of hepatitis C virus
    • Lavanchy D. Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect 2011; 17:107-15.
    • (2011) Clin Microbiol Infect , vol.17 , pp. 107-115
    • Lavanchy, D.1
  • 2
    • 23944506014 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection
    • Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005; 5:558-67.
    • (2005) Lancet Infect Dis , vol.5 , pp. 558-567
    • Shepard, C.W.1    Finelli, L.2    Alter, M.J.3
  • 3
    • 33646250428 scopus 로고    scopus 로고
    • The natural history of hepatitis C virus (HCV) infection
    • Chen SL, Morgan TR. The natural history of hepatitis C virus (HCV) infection. Int J Med Sci 2006; 3:47-52.
    • (2006) Int J Med Sci , vol.3 , pp. 47-52
    • Chen, S.L.1    Morgan, T.R.2
  • 4
    • 0038030890 scopus 로고    scopus 로고
    • HCV infection, malignancy, and liver transplantation
    • Zignego AL, Gragnani L, Di Pietro E, et al. HCV infection, malignancy, and liver transplantation. Transplant Proc 2003; 35:1032-3.
    • (2003) Transplant Proc , vol.35 , pp. 1032-1033
    • Zignego, A.L.1    Gragnani, L.2    Di Pietro, E.3
  • 5
    • 84898990930 scopus 로고    scopus 로고
    • New hepatitis C therapies: the toolbox, strategies, and challenges
    • Pawlotsky JM. New hepatitis C therapies: the toolbox, strategies, and challenges. Gastroenterology 2014; 146:1176-92.
    • (2014) Gastroenterology , vol.146 , pp. 1176-1192
    • Pawlotsky, J.M.1
  • 6
    • 84894707183 scopus 로고    scopus 로고
    • Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource
    • Smith DB, Bukh J, Kuiken C, et al. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology 2014; 59:318-27.
    • (2014) Hepatology , vol.59 , pp. 318-327
    • Smith, D.B.1    Bukh, J.2    Kuiken, C.3
  • 7
    • 84921060015 scopus 로고    scopus 로고
    • Global distribution and prevalence of hepatitis C virus genotypes
    • Messina JP, Humphreys I, Flaxman A, et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology 2015; 61:77-87.
    • (2015) Hepatology , vol.61 , pp. 77-87
    • Messina, J.P.1    Humphreys, I.2    Flaxman, A.3
  • 8
    • 84894378216 scopus 로고    scopus 로고
    • Differential sensitivity of 5'UTRNS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors
    • Li YP, Ramirez S, Humes D, et al. Differential sensitivity of 5'UTRNS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors. Gastroenterology 2014; 146:812-21.e4.
    • (2014) Gastroenterology , vol.146 , pp. 812-821
    • Li, Y.P.1    Ramirez, S.2    Humes, D.3
  • 10
    • 84901586232 scopus 로고    scopus 로고
    • Hepatitis C treatment: an incipient therapeutic revolution
    • deLemos AS, Chung RT. Hepatitis C treatment: an incipient therapeutic revolution. Trends Mol Med 2014; 20:315-21.
    • (2014) Trends Mol Med , vol.20 , pp. 315-321
    • deLemos, A.S.1    Chung, R.T.2
  • 11
    • 84895802673 scopus 로고    scopus 로고
    • Importance of HCV genotype 1 subtypes for drug resistance and response to therapy
    • Wyles DL, Gutierrez JA. Importance of HCV genotype 1 subtypes for drug resistance and response to therapy. J Viral Hepat 2014; 21:229-40.
    • (2014) J Viral Hepat , vol.21 , pp. 229-240
    • Wyles, D.L.1    Gutierrez, J.A.2
  • 12
    • 84877580079 scopus 로고    scopus 로고
    • The presence of resistance mutations to protease and polymerase inhibitors in hepatitis C virus sequences from the Los Alamos databank
    • Alves R, Queiroz AT, Pessoa MG, et al. The presence of resistance mutations to protease and polymerase inhibitors in hepatitis C virus sequences from the Los Alamos databank. J Viral Hepat 2013; 20:414-21.
    • (2013) J Viral Hepat , vol.20 , pp. 414-421
    • Alves, R.1    Queiroz, A.T.2    Pessoa, M.G.3
  • 13
    • 78649644443 scopus 로고    scopus 로고
    • Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors
    • Bae A, Sun SC, Qi X, et al. Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors. Antimicrob Agents Chemother 2010; 54:5288-97.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5288-5297
    • Bae, A.1    Sun, S.C.2    Qi, X.3
  • 14
    • 84890865643 scopus 로고    scopus 로고
    • Second-wave IFN-based triple therapy for HCV genotype 1 infection: simeprevir, faldaprevir and sofosbuvir
    • Asselah T, Marcellin P. Second-wave IFN-based triple therapy for HCV genotype 1 infection: simeprevir, faldaprevir and sofosbuvir. Liver Int 2014; 34(Suppl 1):60-8.
    • (2014) Liver Int , vol.34 , pp. 60-68
    • Asselah, T.1    Marcellin, P.2
  • 15
    • 84911409020 scopus 로고    scopus 로고
    • Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
    • Lawitz E, Sulkowski MS, Ghalib R, et al. Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study. Lancet 2014; 384:1756-65.
    • (2014) Lancet , vol.384 , pp. 1756-1765
    • Lawitz, E.1    Sulkowski, M.S.2    Ghalib, R.3
  • 16
    • 84980052780 scopus 로고    scopus 로고
    • Accessed 21 April, 2015
    • Olysio. EMA/CHMP/137969/2014 Committee for Medicinal Products for Human Use (CHMP), 2014. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion_Initial_authorisation/human/002777/WC500163524.pdf. Accessed 21 April, 2015.
    • (2014)
  • 17
    • 84980052559 scopus 로고    scopus 로고
    • Accessed 21 April, 2015
    • Olysio. U.S. Food and Drug Administration. Reference ID: 3417522, 2013. Available at: http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/205123s001lbl.pdf. Accessed 21 April, 2015.
    • (2013) Reference ID: 3417522
  • 19
    • 84892529894 scopus 로고    scopus 로고
    • EASL Clinical Practice Guidelines: management of hepatitis C virus infection
    • European Association for Study of Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 2014; 60:392-420.
    • (2014) J Hepatol , vol.60 , pp. 392-420
  • 20
    • 84896520682 scopus 로고    scopus 로고
    • Antiviral therapy of hepatitis C in 2014: do we need resistance testing?
    • Schneider MD, Sarrazin C. Antiviral therapy of hepatitis C in 2014: do we need resistance testing? Antiviral Res 2014; 105:64-71.
    • (2014) Antiviral Res , vol.105 , pp. 64-71
    • Schneider, M.D.1    Sarrazin, C.2
  • 21
    • 79960937707 scopus 로고    scopus 로고
    • Evidence for separation of HCV subtype 1a into two distinct clades
    • Pickett BE, Striker R, Lefkowitz EJ. Evidence for separation of HCV subtype 1a into two distinct clades. J Viral Hepat 2011; 18:608-18.
    • (2011) J Viral Hepat , vol.18 , pp. 608-618
    • Pickett, B.E.1    Striker, R.2    Lefkowitz, E.J.3
  • 22
    • 84858690642 scopus 로고    scopus 로고
    • Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy
    • Vicenti I, Rosi A, Saladini F, et al. Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy. J Antimicrob Chemother 2012; 67:984-7.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 984-987
    • Vicenti, I.1    Rosi, A.2    Saladini, F.3
  • 23
    • 84857956447 scopus 로고    scopus 로고
    • Genetic diversity of NS3 protease from Brazilian HCV isolates and possible implications for therapy with direct-acting antiviral drugs
    • Peres-da-Silva A, Almeida AJ, Lampe E. Genetic diversity of NS3 protease from Brazilian HCV isolates and possible implications for therapy with direct-acting antiviral drugs. Mem Inst Oswaldo Cruz 2012; 107:254-61.
    • (2012) Mem Inst Oswaldo Cruz , vol.107 , pp. 254-261
    • Peres-da-Silva, A.1    Almeida, A.J.2    Lampe, E.3
  • 24
    • 84877776880 scopus 로고    scopus 로고
    • Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection
    • Wyles DL. Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection. Top Antivir Med 2012; 20: 139-45.
    • (2012) Top Antivir Med , vol.20 , pp. 139-145
    • Wyles, D.L.1
  • 26
    • 9644301241 scopus 로고    scopus 로고
    • Model selection and model averaging in phylogenetics: advantages of Akaike information criterion and bayesian approaches over likelihood ratio tests
    • Posada D, Buckley TR. Model selection and model averaging in phylogenetics: advantages of Akaike information criterion and bayesian approaches over likelihood ratio tests. Syst Biol 2004; 53:793-808.
    • (2004) Syst Biol , vol.53 , pp. 793-808
    • Posada, D.1    Buckley, T.R.2
  • 27
    • 84857646653 scopus 로고    scopus 로고
    • Origin, evolution, and phylogeography of recent epidemic CHIKV strains
    • Lo Presti A, Ciccozzi M, Cella E, et al. Origin, evolution, and phylogeography of recent epidemic CHIKV strains. Infect Genet Evol 2012; 12:392-8.
    • (2012) Infect Genet Evol , vol.12 , pp. 392-398
    • Lo Presti, A.1    Ciccozzi, M.2    Cella, E.3
  • 28
    • 83455163512 scopus 로고    scopus 로고
    • Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
    • Sierra S, Kaiser R, Lübke N, et al. Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach. J Vis Exp 2011; 58:3264.
    • (2011) J Vis Exp , vol.58 , pp. 3264
    • Sierra, S.1    Kaiser, R.2    Lübke, N.3
  • 29
    • 33645098601 scopus 로고    scopus 로고
    • The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes
    • Van de Vijver DA, Wensing AM, Angarano G, et al. The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes. J Acquir Immune Defic Syndr 2006; 41:352-60.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 352-360
    • Van de Vijver, D.A.1    Wensing, A.M.2    Angarano, G.3
  • 30
    • 0029654006 scopus 로고
    • Revealing the history of infectious disease epidemics through phylogenetic trees
    • Holmes EC, Nee S, Rambaut A, et al. Revealing the history of infectious disease epidemics through phylogenetic trees. Philos Trans R Soc Lond B Biol Sci 1995; 349:33-40.
    • (1995) Philos Trans R Soc Lond B Biol Sci , vol.349 , pp. 33-40
    • Holmes, E.C.1    Nee, S.2    Rambaut, A.3
  • 31
    • 17744381574 scopus 로고    scopus 로고
    • Bayesian coalescent inference of past population dynamics from molecular sequences
    • Drummond AJ, Rambaut A, Shapiro B, et al. Bayesian coalescent inference of past population dynamics from molecular sequences. Mol Biol Evol 2005; 22:1185-92.
    • (2005) Mol Biol Evol , vol.22 , pp. 1185-1192
    • Drummond, A.J.1    Rambaut, A.2    Shapiro, B.3
  • 32
    • 38649110663 scopus 로고    scopus 로고
    • BEAST: Bayesian evolutionary analysis by sampling trees
    • Drummond AJ, Rambaut A. BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 2007; 7:214.
    • (2007) BMC Evol Biol , vol.7 , pp. 214
    • Drummond, A.J.1    Rambaut, A.2
  • 34
    • 27844569825 scopus 로고    scopus 로고
    • Site-to-site variation of synonymous substitution rates
    • Pond SK, Muse SV. Site-to-site variation of synonymous substitution rates. Mol Biol Evol 2005; 22:2375-85.
    • (2005) Mol Biol Evol , vol.22 , pp. 2375-2385
    • Pond, S.K.1    Muse, S.V.2
  • 35
    • 0031972161 scopus 로고    scopus 로고
    • Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene
    • Nielsen R, Yang Z. Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene. Genetics 1998; 148:929-36.
    • (1998) Genetics , vol.148 , pp. 929-936
    • Nielsen, R.1    Yang, Z.2
  • 36
    • 12344314451 scopus 로고    scopus 로고
    • A simple hierarchical approach to modelling distributions of substitution rates
    • Pond SL, Frost SD. A simple hierarchical approach to modelling distributions of substitution rates. Mol Biol Evol 2005; 22:223-34.
    • (2005) Mol Biol Evol , vol.22 , pp. 223-234
    • Pond, S.L.1    Frost, S.D.2
  • 37
    • 74049120411 scopus 로고    scopus 로고
    • The global spread of hepatitis C virus 1a and 1b: a phylodynamic and phylogeographic analysis
    • Magiorkinis G, Magiorkinis E, Paraskevis D, et al. The global spread of hepatitis C virus 1a and 1b: a phylodynamic and phylogeographic analysis. PLoS Med 2009; 6:e1000198.
    • (2009) PLoS Med , vol.6
    • Magiorkinis, G.1    Magiorkinis, E.2    Paraskevis, D.3
  • 38
    • 77951210464 scopus 로고    scopus 로고
    • In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435
    • Lenz O, Verbinnen T, Lin TI, et al. In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435. Antimicrob Agents Chemother 2010; 54:1878-87.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 1878-1887
    • Lenz, O.1    Verbinnen, T.2    Lin, T.I.3
  • 39
    • 84888295678 scopus 로고    scopus 로고
    • Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study
    • Fried MW, Buti M, Dore GJ, et al. Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study. Hepatology 2013; 58: 1918-29.
    • (2013) Hepatology , vol.58 , pp. 1918-1929
    • Fried, M.W.1    Buti, M.2    Dore, G.J.3
  • 40
    • 84906059095 scopus 로고    scopus 로고
    • Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial
    • Manns M, Marcellin P, Poordad F, et al. Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2014; 384:414-26.
    • (2014) Lancet , vol.384 , pp. 414-426
    • Manns, M.1    Marcellin, P.2    Poordad, F.3
  • 41
    • 84892806505 scopus 로고    scopus 로고
    • Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial
    • Zeuzem S, Berg T, Gane E, et al. Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial. Gastroenterology 2014; 146: 430-41.e6.
    • (2014) Gastroenterology , vol.146 , pp. 430-441
    • Zeuzem, S.1    Berg, T.2    Gane, E.3
  • 42
    • 84926667719 scopus 로고    scopus 로고
    • Global origin and transmission of hepatitis C virus nonstructural protein 3 Q80K polymorphism
    • McCloskey RM, Liang RH, Joy JB, et al. Global origin and transmission of hepatitis C virus nonstructural protein 3 Q80K polymorphism. J Infect Dis 2014; 211:1288-95.
    • (2014) J Infect Dis , vol.211 , pp. 1288-1295
    • McCloskey, R.M.1    Liang, R.H.2    Joy, J.B.3
  • 43
    • 84907302681 scopus 로고    scopus 로고
    • Treatment of HCV infection with the novel NS3/4A protease inhibitors
    • De Luca A, Bianco C, Rossetti B. Treatment of HCV infection with the novel NS3/4A protease inhibitors. Curr Opin Pharmacol 2014; 18C: 9-17.
    • (2014) Curr Opin Pharmacol , vol.18C , pp. 9-17
    • De Luca, A.1    Bianco, C.2    Rossetti, B.3
  • 44
    • 84863663083 scopus 로고    scopus 로고
    • HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors
    • Cento V, Mirabelli C, Salpini R, et al. HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors. PLoS One 2012; 7:e39652.
    • (2012) PLoS One , vol.7
    • Cento, V.1    Mirabelli, C.2    Salpini, R.3
  • 45
    • 84862696759 scopus 로고    scopus 로고
    • Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin
    • Larrey D, Lohse AW, de Ledinghen V, et al. Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. J Hepatol 2012; 57:39-46.
    • (2012) J Hepatol , vol.57 , pp. 39-46
    • Larrey, D.1    Lohse, A.W.2    de Ledinghen, V.3
  • 46
    • 81855228070 scopus 로고    scopus 로고
    • Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection
    • Zeuzem S, Asselah T, Angus P. Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology 2011; 141:2047-55.
    • (2011) Gastroenterology , vol.141 , pp. 2047-2055
    • Zeuzem, S.1    Asselah, T.2    Angus, P.3
  • 47
    • 84901598261 scopus 로고    scopus 로고
    • The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
    • Lambert SM, Langley DR, Garnett JA, et al. The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors. Protein Sci 2014; 23:723-34.
    • (2014) Protein Sci , vol.23 , pp. 723-734
    • Lambert, S.M.1    Langley, D.R.2    Garnett, J.A.3
  • 48
    • 84974629255 scopus 로고    scopus 로고
    • Integrated efficacy analysis of four phase 3 studies in HCV genotype 1a-infected patients treated with ABT 450/r/ombitasvir and dasabuvir with or without ribavirin
    • United States of America, Boston, 7-11 November
    • Everson GT, Dusheiko G, Coakley E, et al. Integrated efficacy analysis of four phase 3 studies in HCV genotype 1a-infected patients treated with ABT 450/r/ombitasvir and dasabuvir with or without ribavirin. 65th Annual Meeting of the American Association for the Study of Liver Diseases, United States of America, Boston, 7-11 November 2014, (Abstract 83).
    • (2014) 65th Annual Meeting of the American Association for the Study of Liver Diseases
    • Everson, G.T.1    Dusheiko, G.2    Coakley, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.