-
1
-
-
78751621217
-
Evolving epidemiology of hepatitis C virus
-
Lavanchy D. Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect 2011; 17:107-15.
-
(2011)
Clin Microbiol Infect
, vol.17
, pp. 107-115
-
-
Lavanchy, D.1
-
3
-
-
33646250428
-
The natural history of hepatitis C virus (HCV) infection
-
Chen SL, Morgan TR. The natural history of hepatitis C virus (HCV) infection. Int J Med Sci 2006; 3:47-52.
-
(2006)
Int J Med Sci
, vol.3
, pp. 47-52
-
-
Chen, S.L.1
Morgan, T.R.2
-
4
-
-
0038030890
-
HCV infection, malignancy, and liver transplantation
-
Zignego AL, Gragnani L, Di Pietro E, et al. HCV infection, malignancy, and liver transplantation. Transplant Proc 2003; 35:1032-3.
-
(2003)
Transplant Proc
, vol.35
, pp. 1032-1033
-
-
Zignego, A.L.1
Gragnani, L.2
Di Pietro, E.3
-
5
-
-
84898990930
-
New hepatitis C therapies: the toolbox, strategies, and challenges
-
Pawlotsky JM. New hepatitis C therapies: the toolbox, strategies, and challenges. Gastroenterology 2014; 146:1176-92.
-
(2014)
Gastroenterology
, vol.146
, pp. 1176-1192
-
-
Pawlotsky, J.M.1
-
6
-
-
84894707183
-
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource
-
Smith DB, Bukh J, Kuiken C, et al. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology 2014; 59:318-27.
-
(2014)
Hepatology
, vol.59
, pp. 318-327
-
-
Smith, D.B.1
Bukh, J.2
Kuiken, C.3
-
7
-
-
84921060015
-
Global distribution and prevalence of hepatitis C virus genotypes
-
Messina JP, Humphreys I, Flaxman A, et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology 2015; 61:77-87.
-
(2015)
Hepatology
, vol.61
, pp. 77-87
-
-
Messina, J.P.1
Humphreys, I.2
Flaxman, A.3
-
8
-
-
84894378216
-
Differential sensitivity of 5'UTRNS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors
-
Li YP, Ramirez S, Humes D, et al. Differential sensitivity of 5'UTRNS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors. Gastroenterology 2014; 146:812-21.e4.
-
(2014)
Gastroenterology
, vol.146
, pp. 812-821
-
-
Li, Y.P.1
Ramirez, S.2
Humes, D.3
-
9
-
-
84978809147
-
ABT-493, a potent HCV NS3/4A protease inhibitor with broad genotype coverage
-
Boston, MA, March 3-6
-
Ng T, Reisch T, Middleton T, et al. ABT-493, a potent HCV NS3/4A protease inhibitor with broad genotype coverage. In: 21st Conference on Retroviruses and Opportunistic Infections. Boston, MA, March 3-6, 2014 (Abstract 636).
-
(2014)
21st Conference on Retroviruses and Opportunistic Infections
-
-
Ng, T.1
Reisch, T.2
Middleton, T.3
-
10
-
-
84901586232
-
Hepatitis C treatment: an incipient therapeutic revolution
-
deLemos AS, Chung RT. Hepatitis C treatment: an incipient therapeutic revolution. Trends Mol Med 2014; 20:315-21.
-
(2014)
Trends Mol Med
, vol.20
, pp. 315-321
-
-
deLemos, A.S.1
Chung, R.T.2
-
11
-
-
84895802673
-
Importance of HCV genotype 1 subtypes for drug resistance and response to therapy
-
Wyles DL, Gutierrez JA. Importance of HCV genotype 1 subtypes for drug resistance and response to therapy. J Viral Hepat 2014; 21:229-40.
-
(2014)
J Viral Hepat
, vol.21
, pp. 229-240
-
-
Wyles, D.L.1
Gutierrez, J.A.2
-
12
-
-
84877580079
-
The presence of resistance mutations to protease and polymerase inhibitors in hepatitis C virus sequences from the Los Alamos databank
-
Alves R, Queiroz AT, Pessoa MG, et al. The presence of resistance mutations to protease and polymerase inhibitors in hepatitis C virus sequences from the Los Alamos databank. J Viral Hepat 2013; 20:414-21.
-
(2013)
J Viral Hepat
, vol.20
, pp. 414-421
-
-
Alves, R.1
Queiroz, A.T.2
Pessoa, M.G.3
-
13
-
-
78649644443
-
Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors
-
Bae A, Sun SC, Qi X, et al. Susceptibility of treatment-naive hepatitis C virus (HCV) clinical isolates to HCV protease inhibitors. Antimicrob Agents Chemother 2010; 54:5288-97.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5288-5297
-
-
Bae, A.1
Sun, S.C.2
Qi, X.3
-
14
-
-
84890865643
-
Second-wave IFN-based triple therapy for HCV genotype 1 infection: simeprevir, faldaprevir and sofosbuvir
-
Asselah T, Marcellin P. Second-wave IFN-based triple therapy for HCV genotype 1 infection: simeprevir, faldaprevir and sofosbuvir. Liver Int 2014; 34(Suppl 1):60-8.
-
(2014)
Liver Int
, vol.34
, pp. 60-68
-
-
Asselah, T.1
Marcellin, P.2
-
15
-
-
84911409020
-
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study
-
Lawitz E, Sulkowski MS, Ghalib R, et al. Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study. Lancet 2014; 384:1756-65.
-
(2014)
Lancet
, vol.384
, pp. 1756-1765
-
-
Lawitz, E.1
Sulkowski, M.S.2
Ghalib, R.3
-
16
-
-
84980052780
-
-
Accessed 21 April, 2015
-
Olysio. EMA/CHMP/137969/2014 Committee for Medicinal Products for Human Use (CHMP), 2014. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion_Initial_authorisation/human/002777/WC500163524.pdf. Accessed 21 April, 2015.
-
(2014)
-
-
-
17
-
-
84980052559
-
-
Accessed 21 April, 2015
-
Olysio. U.S. Food and Drug Administration. Reference ID: 3417522, 2013. Available at: http://www.accessdata.fda.gov/drugsatfda_docs/label/2013/205123s001lbl.pdf. Accessed 21 April, 2015.
-
(2013)
Reference ID: 3417522
-
-
-
19
-
-
84892529894
-
EASL Clinical Practice Guidelines: management of hepatitis C virus infection
-
European Association for Study of Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 2014; 60:392-420.
-
(2014)
J Hepatol
, vol.60
, pp. 392-420
-
-
-
20
-
-
84896520682
-
Antiviral therapy of hepatitis C in 2014: do we need resistance testing?
-
Schneider MD, Sarrazin C. Antiviral therapy of hepatitis C in 2014: do we need resistance testing? Antiviral Res 2014; 105:64-71.
-
(2014)
Antiviral Res
, vol.105
, pp. 64-71
-
-
Schneider, M.D.1
Sarrazin, C.2
-
21
-
-
79960937707
-
Evidence for separation of HCV subtype 1a into two distinct clades
-
Pickett BE, Striker R, Lefkowitz EJ. Evidence for separation of HCV subtype 1a into two distinct clades. J Viral Hepat 2011; 18:608-18.
-
(2011)
J Viral Hepat
, vol.18
, pp. 608-618
-
-
Pickett, B.E.1
Striker, R.2
Lefkowitz, E.J.3
-
22
-
-
84858690642
-
Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy
-
Vicenti I, Rosi A, Saladini F, et al. Naturally occurring hepatitis C virus (HCV) NS3/4A protease inhibitor resistance-related mutations in HCV genotype 1-infected subjects in Italy. J Antimicrob Chemother 2012; 67:984-7.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 984-987
-
-
Vicenti, I.1
Rosi, A.2
Saladini, F.3
-
23
-
-
84857956447
-
Genetic diversity of NS3 protease from Brazilian HCV isolates and possible implications for therapy with direct-acting antiviral drugs
-
Peres-da-Silva A, Almeida AJ, Lampe E. Genetic diversity of NS3 protease from Brazilian HCV isolates and possible implications for therapy with direct-acting antiviral drugs. Mem Inst Oswaldo Cruz 2012; 107:254-61.
-
(2012)
Mem Inst Oswaldo Cruz
, vol.107
, pp. 254-261
-
-
Peres-da-Silva, A.1
Almeida, A.J.2
Lampe, E.3
-
24
-
-
84877776880
-
Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection
-
Wyles DL. Beyond telaprevir and boceprevir: resistance and new agents for hepatitis C virus infection. Top Antivir Med 2012; 20: 139-45.
-
(2012)
Top Antivir Med
, vol.20
, pp. 139-145
-
-
Wyles, D.L.1
-
26
-
-
9644301241
-
Model selection and model averaging in phylogenetics: advantages of Akaike information criterion and bayesian approaches over likelihood ratio tests
-
Posada D, Buckley TR. Model selection and model averaging in phylogenetics: advantages of Akaike information criterion and bayesian approaches over likelihood ratio tests. Syst Biol 2004; 53:793-808.
-
(2004)
Syst Biol
, vol.53
, pp. 793-808
-
-
Posada, D.1
Buckley, T.R.2
-
27
-
-
84857646653
-
Origin, evolution, and phylogeography of recent epidemic CHIKV strains
-
Lo Presti A, Ciccozzi M, Cella E, et al. Origin, evolution, and phylogeography of recent epidemic CHIKV strains. Infect Genet Evol 2012; 12:392-8.
-
(2012)
Infect Genet Evol
, vol.12
, pp. 392-398
-
-
Lo Presti, A.1
Ciccozzi, M.2
Cella, E.3
-
28
-
-
83455163512
-
Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach
-
Sierra S, Kaiser R, Lübke N, et al. Prediction of HIV-1 coreceptor usage (tropism) by sequence analysis using a genotypic approach. J Vis Exp 2011; 58:3264.
-
(2011)
J Vis Exp
, vol.58
, pp. 3264
-
-
Sierra, S.1
Kaiser, R.2
Lübke, N.3
-
29
-
-
33645098601
-
The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes
-
Van de Vijver DA, Wensing AM, Angarano G, et al. The calculated genetic barrier for antiretroviral drug resistance substitutions is largely similar for different HIV-1 subtypes. J Acquir Immune Defic Syndr 2006; 41:352-60.
-
(2006)
J Acquir Immune Defic Syndr
, vol.41
, pp. 352-360
-
-
Van de Vijver, D.A.1
Wensing, A.M.2
Angarano, G.3
-
30
-
-
0029654006
-
Revealing the history of infectious disease epidemics through phylogenetic trees
-
Holmes EC, Nee S, Rambaut A, et al. Revealing the history of infectious disease epidemics through phylogenetic trees. Philos Trans R Soc Lond B Biol Sci 1995; 349:33-40.
-
(1995)
Philos Trans R Soc Lond B Biol Sci
, vol.349
, pp. 33-40
-
-
Holmes, E.C.1
Nee, S.2
Rambaut, A.3
-
31
-
-
17744381574
-
Bayesian coalescent inference of past population dynamics from molecular sequences
-
Drummond AJ, Rambaut A, Shapiro B, et al. Bayesian coalescent inference of past population dynamics from molecular sequences. Mol Biol Evol 2005; 22:1185-92.
-
(2005)
Mol Biol Evol
, vol.22
, pp. 1185-1192
-
-
Drummond, A.J.1
Rambaut, A.2
Shapiro, B.3
-
32
-
-
38649110663
-
BEAST: Bayesian evolutionary analysis by sampling trees
-
Drummond AJ, Rambaut A. BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 2007; 7:214.
-
(2007)
BMC Evol Biol
, vol.7
, pp. 214
-
-
Drummond, A.J.1
Rambaut, A.2
-
34
-
-
27844569825
-
Site-to-site variation of synonymous substitution rates
-
Pond SK, Muse SV. Site-to-site variation of synonymous substitution rates. Mol Biol Evol 2005; 22:2375-85.
-
(2005)
Mol Biol Evol
, vol.22
, pp. 2375-2385
-
-
Pond, S.K.1
Muse, S.V.2
-
35
-
-
0031972161
-
Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene
-
Nielsen R, Yang Z. Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene. Genetics 1998; 148:929-36.
-
(1998)
Genetics
, vol.148
, pp. 929-936
-
-
Nielsen, R.1
Yang, Z.2
-
36
-
-
12344314451
-
A simple hierarchical approach to modelling distributions of substitution rates
-
Pond SL, Frost SD. A simple hierarchical approach to modelling distributions of substitution rates. Mol Biol Evol 2005; 22:223-34.
-
(2005)
Mol Biol Evol
, vol.22
, pp. 223-234
-
-
Pond, S.L.1
Frost, S.D.2
-
37
-
-
74049120411
-
The global spread of hepatitis C virus 1a and 1b: a phylodynamic and phylogeographic analysis
-
Magiorkinis G, Magiorkinis E, Paraskevis D, et al. The global spread of hepatitis C virus 1a and 1b: a phylodynamic and phylogeographic analysis. PLoS Med 2009; 6:e1000198.
-
(2009)
PLoS Med
, vol.6
-
-
Magiorkinis, G.1
Magiorkinis, E.2
Paraskevis, D.3
-
38
-
-
77951210464
-
In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435
-
Lenz O, Verbinnen T, Lin TI, et al. In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435. Antimicrob Agents Chemother 2010; 54:1878-87.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1878-1887
-
-
Lenz, O.1
Verbinnen, T.2
Lin, T.I.3
-
39
-
-
84888295678
-
Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study
-
Fried MW, Buti M, Dore GJ, et al. Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study. Hepatology 2013; 58: 1918-29.
-
(2013)
Hepatology
, vol.58
, pp. 1918-1929
-
-
Fried, M.W.1
Buti, M.2
Dore, G.J.3
-
40
-
-
84906059095
-
Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial
-
Manns M, Marcellin P, Poordad F, et al. Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2014; 384:414-26.
-
(2014)
Lancet
, vol.384
, pp. 414-426
-
-
Manns, M.1
Marcellin, P.2
Poordad, F.3
-
41
-
-
84892806505
-
Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial
-
Zeuzem S, Berg T, Gane E, et al. Simeprevir increases rate of sustained virologic response among treatment-experienced patients with HCV genotype-1 infection: a phase IIb trial. Gastroenterology 2014; 146: 430-41.e6.
-
(2014)
Gastroenterology
, vol.146
, pp. 430-441
-
-
Zeuzem, S.1
Berg, T.2
Gane, E.3
-
42
-
-
84926667719
-
Global origin and transmission of hepatitis C virus nonstructural protein 3 Q80K polymorphism
-
McCloskey RM, Liang RH, Joy JB, et al. Global origin and transmission of hepatitis C virus nonstructural protein 3 Q80K polymorphism. J Infect Dis 2014; 211:1288-95.
-
(2014)
J Infect Dis
, vol.211
, pp. 1288-1295
-
-
McCloskey, R.M.1
Liang, R.H.2
Joy, J.B.3
-
43
-
-
84907302681
-
Treatment of HCV infection with the novel NS3/4A protease inhibitors
-
De Luca A, Bianco C, Rossetti B. Treatment of HCV infection with the novel NS3/4A protease inhibitors. Curr Opin Pharmacol 2014; 18C: 9-17.
-
(2014)
Curr Opin Pharmacol
, vol.18C
, pp. 9-17
-
-
De Luca, A.1
Bianco, C.2
Rossetti, B.3
-
44
-
-
84863663083
-
HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors
-
Cento V, Mirabelli C, Salpini R, et al. HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors. PLoS One 2012; 7:e39652.
-
(2012)
PLoS One
, vol.7
-
-
Cento, V.1
Mirabelli, C.2
Salpini, R.3
-
45
-
-
84862696759
-
Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin
-
Larrey D, Lohse AW, de Ledinghen V, et al. Rapid and strong antiviral activity of the non-nucleosidic NS5B polymerase inhibitor BI 207127 in combination with peginterferon alfa 2a and ribavirin. J Hepatol 2012; 57:39-46.
-
(2012)
J Hepatol
, vol.57
, pp. 39-46
-
-
Larrey, D.1
Lohse, A.W.2
de Ledinghen, V.3
-
46
-
-
81855228070
-
Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection
-
Zeuzem S, Asselah T, Angus P. Efficacy of the protease inhibitor BI 201335, polymerase inhibitor BI 207127, and ribavirin in patients with chronic HCV infection. Gastroenterology 2011; 141:2047-55.
-
(2011)
Gastroenterology
, vol.141
, pp. 2047-2055
-
-
Zeuzem, S.1
Asselah, T.2
Angus, P.3
-
47
-
-
84901598261
-
The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors
-
Lambert SM, Langley DR, Garnett JA, et al. The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors. Protein Sci 2014; 23:723-34.
-
(2014)
Protein Sci
, vol.23
, pp. 723-734
-
-
Lambert, S.M.1
Langley, D.R.2
Garnett, J.A.3
-
48
-
-
84974629255
-
Integrated efficacy analysis of four phase 3 studies in HCV genotype 1a-infected patients treated with ABT 450/r/ombitasvir and dasabuvir with or without ribavirin
-
United States of America, Boston, 7-11 November
-
Everson GT, Dusheiko G, Coakley E, et al. Integrated efficacy analysis of four phase 3 studies in HCV genotype 1a-infected patients treated with ABT 450/r/ombitasvir and dasabuvir with or without ribavirin. 65th Annual Meeting of the American Association for the Study of Liver Diseases, United States of America, Boston, 7-11 November 2014, (Abstract 83).
-
(2014)
65th Annual Meeting of the American Association for the Study of Liver Diseases
-
-
Everson, G.T.1
Dusheiko, G.2
Coakley, E.3
|