Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection
McHutchison JG, Everson GT, Gordon SC, et al. Telaprevir with peginterferon and ribavirin for chronic HCV genotype 1 infection. N Engl J Med. 2009;360(18):1827-1838.
(2009)N Engl J Med., vol.360, Issue.18, pp. 1827-1838
Telaprevir and peginterferon with or without ribavirin for chronic HCV infection
Hezode C, Forestier N, Dusheiko G, et al. Telaprevir and peginterferon with or without ribavirin for chronic HCV infection. N Engl J Med. 2009;360(18):1839-1850.
(2009)N Engl J Med., vol.360, Issue.18, pp. 1839-1850
TMC435 in combination with peginterferon alpha-2a/ribavirin in treatment-naive patients infected with HCV genotype 1: Virology analysis of the PILLAR study. [Abstract 1329.]
November 4-8, San Francisco, CA
Lenz O, Fevery B, Vijgen L, et al. TMC435 in combination with peginterferon alpha-2a/ribavirin in treatment-naive patients infected with HCV genotype 1: virology analysis of the PILLAR study. [Abstract 1329.] 62nd Annual Meeting of the American Association for the Study of Liver Disease (AASLD). November 4-8, 2011; San Francisco, CA.
Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: In vitro and in vivo correlations
Fridell RA, Wang C, Sun JH, et al. Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in humans: in vitro and in vivo correlations. Hepatology. 2011;54(6):1924-1935.
Dual oral therapy with the NS5A inhibitor daclatasvir (BMS-790052) and NS3 protease inhibitor asunaprevir (BMS-650032) in HCV genotype 1b-infected null responders or ineligible/intolerant to peginterferon. [Abstract 14.]
April 18-22, Barcelona, Spain
Suzuki F, Ikeda K, Toyota J, et al. Dual oral therapy with the NS5A inhibitor daclatasvir (BMS-790052) and NS3 protease inhibitor asunaprevir (BMS-650032) in HCV genotype 1b-infected null responders or ineligible/intolerant to peginterferon. [Abstract 14.] 47th Annual Meeting of the European Association for the Study of the Liver (EASL). April 18-22, 2012; Barcelona, Spain.
Interim sustained virologic response rates in treatment-naïve HCV genotype 1a and 1b patients treated for 12 or 24 weeks with an interferon-free all-oral Quad regimen. [Abstract 1421.]
(EASL). April 18-22, Barcelona, Spain
Sulkowski M, Rodriguez-Torres M, Lawitz E, et al. Interim sustained virologic response rates in treatment-naïve HCV genotype 1a and 1b patients treated for 12 or 24 weeks with an interferon-free all-oral Quad regimen. [Abstract 1421.] 47th Annual Meeting of the European Association for the Study of the Liver (EASL). April 18-22, 2012; Barcelona, Spain.
A 12-week interferon-free regimen of ABT-450/r + ABT-333 + ribavirin achieved SVR12 in more than 90% of treatmentnaïve HCV genotype-1-infected subjects and 47% of previous non-responders. [Abstract 1399.]
April 18-22, Barcelona, Spain
Poordad F, Lawitz E, Kowdley KV, et al. A 12-week interferon-free regimen of ABT-450/r + ABT-333 + ribavirin achieved SVR12 in more than 90% of treatmentnaïve HCV genotype-1-infected subjects and 47% of previous non-responders. [Abstract 1399.] 47th Annual Meeting of the European Association for the Study of the Liver (EASL). April 18-22, 2012; Barcelona, Spain.
ELECTRON: Once daily PSI-7977 plus RBV in HCV GT1/2/3. [Abstract 1113.]
April 18-22, Barcelona, Spain
Gane EJ, Stedman CA, Hyland RH, et al. ELECTRON: once daily PSI-7977 plus RBV in HCV GT1/2/3. [Abstract 1113.] 47th Annual Meeting of the European Association for the Study of the Liver (EASL). April 18-22, 2012; Barcelona, Spain.
100% Rapid virologic response for PSI-7977 + ribavirin in genotype 1 null responders (ELECTRON): Early viral decline similar to that observed in genotype 1 and genotype 2/3 treatment-naïve patients. [Abstract 54LB.]
March 5-8, Seattle, WA
Gane E, Stedman C, Anderson J, et al. 100% Rapid virologic response for PSI-7977 + ribavirin in genotype 1 null responders (ELECTRON): early viral decline similar to that observed in genotype 1 and genotype 2/3 treatment-naïve patients. [Abstract 54LB.] 19th Conference on Retroviruses and Opportunistic Infections (CROI). March 5-8, 2012; Seattle, WA.
Potent viral suppression with the all-oral combination of daclatasvir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor), +/-ribavirin, in treatment-naive patients with chronic HCV GT1, 2, or 3 (100% SVR gt1, 91% gt2). [Abstract 1422.]
April 18-22, Barcelona, Spain
Sulkowski MS, Gardiner D, Lawitz E, et al. Potent viral suppression with the all-oral combination of daclatasvir (NS5A inhibitor) and GS-7977 (nucleotide NS5B inhibitor), +/-ribavirin, in treatment-naive patients with chronic HCV GT1, 2, or 3 (100% SVR gt1, 91% gt2). [Abstract 1422.] 47th Annual Meeting of the European Association for the Study of the Liver (EASL). April 18-22, 2012; Barcelona, Spain.