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Volumn 22, Issue 9, 2016, Pages 659-669

2016 ACC/AHA/HFSA Focused Update on New Pharmacological Therapy for Heart Failure: An Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America

Author keywords

AHA Scientific Statements; angioedema; angiotensin receptor blockers; angiotensin receptor neprilysin inhibitor; angiotensin converting enzyme inhibitors; beta blockers; focused update; heart failure; ivabradine; natriuretic peptides

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IVABRADINE;

EID: 84979743506     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2016.07.001     Document Type: Article
Times cited : (71)

References (40)
  • 1
    • 81255156559 scopus 로고    scopus 로고
    • Methodology Manual and Policies From the ACCF/AHA Task Force on Practice Guidelines
    • Available at: American College of Cardiology and American Heart Association; Accessed April 7, 2016, http://my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/documents/downloadable/ucm_319826.pdf
    • 1 ACCF/AHA Task Force on Practice Guidelines, Methodology Manual and Policies From the ACCF/AHA Task Force on Practice Guidelines. Available at: http://assets.cardiosource.com/Methodology_Manual_for_ACC_AHA_Writing_Committees.pdf http://my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/documents/downloadable/ucm_319826.pdf, 2010 American College of Cardiology and American Heart Association; Accessed April 7, 2016.
    • (2010)
    • ACCF/AHA Task Force on Practice Guidelines1
  • 2
    • 84990201969 scopus 로고    scopus 로고
    • Clinical practice guidelines we can trust
    • National Academies Press Washington, DC
    • 2 Committee on Standards for Developing Trustworthy Clinical Practice Guidelines, Institute of Medicine (US), Clinical practice guidelines we can trust. 2011, National Academies Press, Washington, DC.
    • (2011)
  • 3
    • 79960218580 scopus 로고    scopus 로고
    • Finding what works in health care: standards for systematic reviews
    • National Academies Press Washington, DC
    • 3 Committee on Standards for Systematic Reviews of Comparative Effectiveness Research, Institute of Medicine (US), Finding what works in health care: standards for systematic reviews. 2011, National Academies Press, Washington, DC.
    • (2011)
  • 4
    • 84874808873 scopus 로고    scopus 로고
    • ACCF/AHA clinical practice guideline methodology summit report: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • 4 Jacobs, A.K., Kushner, F.G., Ettinger, S.M., Guyton, R.A., Anderson, J.L., Ohman, E.M., et al. ACCF/AHA clinical practice guideline methodology summit report: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 127 (2013), 268–310.
    • (2013) Circulation , vol.127 , pp. 268-310
    • Jacobs, A.K.1    Kushner, F.G.2    Ettinger, S.M.3    Guyton, R.A.4    Anderson, J.L.5    Ohman, E.M.6
  • 5
    • 84918553076 scopus 로고    scopus 로고
    • The evolution and future of ACC/AHA clinical practice guidelines: a 30-year journey: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • 5 Jacobs, A.K., Anderson, J.L., Halperin, J.L., The evolution and future of ACC/AHA clinical practice guidelines: a 30-year journey: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 130 (2014), 1208–1217.
    • (2014) Circulation , vol.130 , pp. 1208-1217
    • Jacobs, A.K.1    Anderson, J.L.2    Halperin, J.L.3
  • 6
    • 84901935185 scopus 로고    scopus 로고
    • ACC/AHA statement on cost/value methodology in clinical practice guidelines and performance measures: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and Task Force on Practice Guidelines
    • 6 Anderson, J.L., Heidenreich, P.A., Barnett, P.G., Creager, M.A., Fonarow, G.C., Gibbons, R.J., et al. ACC/AHA statement on cost/value methodology in clinical practice guidelines and performance measures: a report of the American College of Cardiology/American Heart Association Task Force on Performance Measures and Task Force on Practice Guidelines. Circulation 129 (2014), 2329–2345.
    • (2014) Circulation , vol.129 , pp. 2329-2345
    • Anderson, J.L.1    Heidenreich, P.A.2    Barnett, P.G.3    Creager, M.A.4    Fonarow, G.C.5    Gibbons, R.J.6
  • 7
    • 84918589184 scopus 로고    scopus 로고
    • AHA/ACC/HHS strategies to enhance application of clinical practice guidelines in patients with cardiovascular disease and comorbid conditions: from the American Heart Association, American College of Cardiology, and U.S. Department of Health and Human Services
    • 7 Arnett, D.K., Goodman, R.A., Halperin, J.L., Anderson, J.L., Parekh, A.K., Zoghbi, W.A., AHA/ACC/HHS strategies to enhance application of clinical practice guidelines in patients with cardiovascular disease and comorbid conditions: from the American Heart Association, American College of Cardiology, and U.S. Department of Health and Human Services. Circulation 130 (2014), 1662–1667.
    • (2014) Circulation , vol.130 , pp. 1662-1667
    • Arnett, D.K.1    Goodman, R.A.2    Halperin, J.L.3    Anderson, J.L.4    Parekh, A.K.5    Zoghbi, W.A.6
  • 8
    • 84944346071 scopus 로고    scopus 로고
    • Further evolution of the ACC/AHA clinical practice guideline recommendation classification system: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
    • 8 Halperin, J.L., Levine, G.N., Al-Khatib, S.M., Birtcher, K.K., Bozkurt, B., Brindis, R.G., et al. Further evolution of the ACC/AHA clinical practice guideline recommendation classification system: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 133 (2016), 1426–1428.
    • (2016) Circulation , vol.133 , pp. 1426-1428
    • Halperin, J.L.1    Levine, G.N.2    Al-Khatib, S.M.3    Birtcher, K.K.4    Bozkurt, B.5    Brindis, R.G.6
  • 9
    • 0023266532 scopus 로고
    • Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group
    • 9 Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group. N Engl J Med 316 (1987), 1429–1435.
    • (1987) N Engl J Med , vol.316 , pp. 1429-1435
  • 10
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators
    • 10 Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. The SOLVD Investigators. N Engl J Med 325 (1991), 293–302.
    • (1991) N Engl J Med , vol.325 , pp. 293-302
  • 11
    • 0033534085 scopus 로고    scopus 로고
    • Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. ATLAS Study Group
    • 11 Packer, M., Poole-Wilson, P.A., Armstrong, P.W., Cleland, J.G., Horowitz, J.D., Massie, B.M., et al. Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. ATLAS Study Group. Circulation 100 (1999), 2312–2318.
    • (1999) Circulation , vol.100 , pp. 2312-2318
    • Packer, M.1    Poole-Wilson, P.A.2    Armstrong, P.W.3    Cleland, J.G.4    Horowitz, J.D.5    Massie, B.M.6
  • 12
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators
    • 12 Pfeffer, M.A., Braunwald, E., Moye, L.A., Basta, L., Brown, E.J. Jr, Cuddy, T.E., et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. N Engl J Med 327 (1992), 669–677.
    • (1992) N Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3    Basta, L.4    Brown, E.J.5    Cuddy, T.E.6
  • 13
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators
    • 13 Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators. Lancet 342 (1993), 821–828.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 14
    • 9044239676 scopus 로고
    • A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group
    • 14 Køber, L., Torp-Pedersen, C., Carlsen, J.E., Bagger, H., Eliasen, P., Lyngborg, K., et al. A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group. N Engl J Med 333 (1995), 1670–1676.
    • (1995) N Engl J Med , vol.333 , pp. 1670-1676
    • Køber, L.1    Torp-Pedersen, C.2    Carlsen, J.E.3    Bagger, H.4    Eliasen, P.5    Lyngborg, K.6
  • 15
    • 0035818884 scopus 로고    scopus 로고
    • A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • 15 Cohn, J.N., Tognoni, G., Valsartan Heart Failure Trial Investigators. A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. N Engl J Med 345 (2001), 1667–1675.
    • (2001) N Engl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 16
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • 16 Pfeffer, M.A., McMurray, J.J.V., Velazquez, E.J., Rouleau, J.L., Køber, L., Maggioni, A.P., et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med 349 (2003), 1893–1906.
    • (2003) N Engl J Med , vol.349 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.V.2    Velazquez, E.J.3    Rouleau, J.L.4    Køber, L.5    Maggioni, A.P.6
  • 17
    • 71549127400 scopus 로고    scopus 로고
    • Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial
    • 17 Konstam, M.A., Neaton, J.D., Dickstein, K., Drexler, H., Komajda, M., Martinez, F.A., et al. Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial. Lancet 374 (2009), 1840–1848.
    • (2009) Lancet , vol.374 , pp. 1840-1848
    • Konstam, M.A.1    Neaton, J.D.2    Dickstein, K.3    Drexler, H.4    Komajda, M.5    Martinez, F.A.6
  • 18
    • 0042410539 scopus 로고    scopus 로고
    • Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme
    • 18 Pfeffer, M.A., Swedberg, K., Granger, C.B., Held, P., McMurray, J.J., Michelson, E.L., et al. Effects of candesartan on mortality and morbidity in patients with chronic heart failure: the CHARM-Overall programme. Lancet 362 (2003), 759–766.
    • (2003) Lancet , vol.362 , pp. 759-766
    • Pfeffer, M.A.1    Swedberg, K.2    Granger, C.B.3    Held, P.4    McMurray, J.J.5    Michelson, E.L.6
  • 20
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • 20 Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 353 (1999), 2001–2007.
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 21
    • 0037159310 scopus 로고    scopus 로고
    • Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study
    • 21 Packer, M., Fowler, M.B., Roecker, E.B., Coats, A.J., Katus, H.A., Krum, H., et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation 106 (2002), 2194–2199.
    • (2002) Circulation , vol.106 , pp. 2194-2199
    • Packer, M.1    Fowler, M.B.2    Roecker, E.B.3    Coats, A.J.4    Katus, H.A.5    Krum, H.6
  • 22
    • 84885845957 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • 22 Yancy, C.W., Jessup, M., Bozkurt, B., Butler, J., Casey, D.E. Jr, Drazner, M.H., et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 128 (2013), e240–327.
    • (2013) Circulation , vol.128 , pp. e240-327
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3    Butler, J.4    Casey, D.E.5    Drazner, M.H.6
  • 23
    • 84886023778 scopus 로고    scopus 로고
    • Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure)
    • 23 Eschalier, R., McMurray, J.J.V., Swedberg, K., van Veldhuisen, D.J., Krum, H., Pocock, S.J., et al. Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure). J Am Coll Cardiol 62 (2013), 1585–1593.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1585-1593
    • Eschalier, R.1    McMurray, J.J.V.2    Swedberg, K.3    van Veldhuisen, D.J.4    Krum, H.5    Pocock, S.J.6
  • 24
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
    • 24 Pitt, B., Zannad, F., Remme, W.J., Cody, R., Castaigne, A., Perez, A., et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341 (1999), 709–717.
    • (1999) N Engl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3    Cody, R.4    Castaigne, A.5    Perez, A.6
  • 25
    • 0028955321 scopus 로고
    • Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials
    • 25 Garg, R., Yusuf, S., Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials. JAMA 273 (1995), 1450–1456.
    • (1995) JAMA , vol.273 , pp. 1450-1456
    • Garg, R.1    Yusuf, S.2
  • 26
    • 77955924405 scopus 로고    scopus 로고
    • Sex-dependent and race-dependent association of XPNPEP2 C-2399A polymorphism with angiotensin-converting enzyme inhibitor-associated angioedema
    • 26 Woodard-Grice, A.V., Lucisano, A.C., Byrd, J.B., Stone, E.R., Simmons, W.H., Brown, N.J., Sex-dependent and race-dependent association of XPNPEP2 C-2399A polymorphism with angiotensin-converting enzyme inhibitor-associated angioedema. Pharmacogenet Genomics 20 (2010), 532–536.
    • (2010) Pharmacogenet Genomics , vol.20 , pp. 532-536
    • Woodard-Grice, A.V.1    Lucisano, A.C.2    Byrd, J.B.3    Stone, E.R.4    Simmons, W.H.5    Brown, N.J.6
  • 27
    • 42049107348 scopus 로고    scopus 로고
    • Telmisartan, ramipril, or both in patients at high risk for vascular events. ONTARGET Investigators
    • 27 Yusuf, S., Teo, K.K., Pogue, J., Dyal, L., Copland, I., Schumacher, H., et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. ONTARGET Investigators. N Engl J Med 358 (2008), 1547–1559.
    • (2008) N Engl J Med , vol.358 , pp. 1547-1559
    • Yusuf, S.1    Teo, K.K.2    Pogue, J.3    Dyal, L.4    Copland, I.5    Schumacher, H.6
  • 28
    • 53049109468 scopus 로고    scopus 로고
    • Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators
    • 28 Yusuf, S., Teo, K., Anderson, C., Pogue, J., Dyal, L., Copland, I., et al. Effects of the angiotensin-receptor blocker telmisartan on cardiovascular events in high-risk patients intolerant to angiotensin-converting enzyme inhibitors: a randomised controlled trial. Telmisartan Randomised AssessmeNt Study in ACE iNtolerant subjects with cardiovascular Disease (TRANSCEND) Investigators. Lancet 372 (2008), 1174–1183.
    • (2008) Lancet , vol.372 , pp. 1174-1183
    • Yusuf, S.1    Teo, K.2    Anderson, C.3    Pogue, J.4    Dyal, L.5    Copland, I.6
  • 29
    • 84988921332 scopus 로고    scopus 로고
    • Novartis Pharmaceuticals Corporation Hanover, NJ
    • 29 Entresto [package insert], 2015, Novartis Pharmaceuticals Corporation, Hanover, NJ.
    • (2015) Entresto [package insert]
  • 30
    • 84867745957 scopus 로고    scopus 로고
    • The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial
    • 30 Solomon, S.D., Zile, M., Pieske, B., Voors, A., Shah, A., Kraigher-Krainer, E., et al. The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial. Lancet 380 (2012), 1387–1395.
    • (2012) Lancet , vol.380 , pp. 1387-1395
    • Solomon, S.D.1    Zile, M.2    Pieske, B.3    Voors, A.4    Shah, A.5    Kraigher-Krainer, E.6
  • 31
    • 0037143601 scopus 로고    scopus 로고
    • Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE)
    • 31 Packer, M., Califf, R.M., Konstam, M.A., Krum, H., McMurray, J.J., Rouleau, J.L., et al. Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE). Circulation 106 (2002), 920–926.
    • (2002) Circulation , vol.106 , pp. 920-926
    • Packer, M.1    Califf, R.M.2    Konstam, M.A.3    Krum, H.4    McMurray, J.J.5    Rouleau, J.L.6
  • 32
    • 1642452758 scopus 로고    scopus 로고
    • Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial
    • 32 Kostis, J.B., Packer, M., Black, H.R., Schmieder, R., Henry, D., Levy, E., Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial. Am J Hypertens 17 (2004), 103–111.
    • (2004) Am J Hypertens , vol.17 , pp. 103-111
    • Kostis, J.B.1    Packer, M.2    Black, H.R.3    Schmieder, R.4    Henry, D.5    Levy, E.6
  • 33
    • 84926135895 scopus 로고    scopus 로고
    • Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure
    • 33 Vardeny, O., Miller, R., Solomon, S.D., Combined neprilysin and renin-angiotensin system inhibition for the treatment of heart failure. JACC Heart Fail 2 (2014), 663–670.
    • (2014) JACC Heart Fail , vol.2 , pp. 663-670
    • Vardeny, O.1    Miller, R.2    Solomon, S.D.3
  • 34
    • 0034686930 scopus 로고    scopus 로고
    • Vasopeptidase inhibition and angio-oedema
    • 34 Messerli, F.H., Nussberger, J., Vasopeptidase inhibition and angio-oedema. Lancet 356 (2000), 608–609.
    • (2000) Lancet , vol.356 , pp. 608-609
    • Messerli, F.H.1    Nussberger, J.2
  • 35
    • 84924402407 scopus 로고    scopus 로고
    • The path to an angiotensin receptor antagonist-neprilysin inhibitor in the treatment of heart failure
    • 35 Braunwald, E., The path to an angiotensin receptor antagonist-neprilysin inhibitor in the treatment of heart failure. J Am Coll Cardiol 65 (2015), 1029–1041.
    • (2015) J Am Coll Cardiol , vol.65 , pp. 1029-1041
    • Braunwald, E.1
  • 36
    • 77950628157 scopus 로고    scopus 로고
    • Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study
    • 36 Ruilope, L.M., Dukat, A., Böhm, M., Lacourcière, Y., Gong, J., Lefkowitz, M.P., Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study. Lancet 375 (2010), 1255–1266.
    • (2010) Lancet , vol.375 , pp. 1255-1266
    • Ruilope, L.M.1    Dukat, A.2    Böhm, M.3    Lacourcière, Y.4    Gong, J.5    Lefkowitz, M.P.6
  • 37
    • 84951741842 scopus 로고    scopus 로고
    • Influence of cardiovascular and noncardiovascular co-morbidities on outcomes and treatment effect of heart rate reduction with ivabradine in stable heart failure (from the SHIFT trial)
    • 37 Böhm, M., Robertson, M., Ford, I., Borer, J.S., Komajda, M., Kindermann, I., et al. Influence of cardiovascular and noncardiovascular co-morbidities on outcomes and treatment effect of heart rate reduction with ivabradine in stable heart failure (from the SHIFT trial). Am J Cardiol 116 (2015), 1890–1897.
    • (2015) Am J Cardiol , vol.116 , pp. 1890-1897
    • Böhm, M.1    Robertson, M.2    Ford, I.3    Borer, J.S.4    Komajda, M.5    Kindermann, I.6
  • 38
    • 77956612624 scopus 로고    scopus 로고
    • Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study
    • 38 Swedberg, K., Komajda, M., Böhm, M., Borer, J.S., Ford, I., Dubost-Brama, A., et al. Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study. Lancet 376 (2010), 875–885.
    • (2010) Lancet , vol.376 , pp. 875-885
    • Swedberg, K.1    Komajda, M.2    Böhm, M.3    Borer, J.S.4    Ford, I.5    Dubost-Brama, A.6
  • 39
    • 84907424112 scopus 로고    scopus 로고
    • Ivabradine in stable coronary artery disease without clinical heart failure
    • 39 Fox, K., Ford, I., Steg, P.G., Tardif, J.C., Tendera, M., Ferrari, R., et al. Ivabradine in stable coronary artery disease without clinical heart failure. N Engl J Med 371 (2014), 1091–1099.
    • (2014) N Engl J Med , vol.371 , pp. 1091-1099
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tardif, J.C.4    Tendera, M.5    Ferrari, R.6
  • 40
    • 50649109186 scopus 로고    scopus 로고
    • Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial
    • 40 Fox, K., Ford, I., Steg, P.G., Tendera, M., Ferrari, R., BEAUTIFUL Investigators. Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial. Lancet 372 (2008), 807–816.
    • (2008) Lancet , vol.372 , pp. 807-816
    • Fox, K.1    Ford, I.2    Steg, P.G.3    Tendera, M.4    Ferrari, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.