Endothelial cell-derived von willebrand factor is the major determinant that mediates von willebrand factor-dependent acute Ischemic Stroke by promoting postischemic thrombo-inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 9, 2016, Pages 1829-1837

  Dhanesha, Nirav ^a   Prakash, Prem ^a   Doddapattar, Prakash ^a   Khanna, Ira ^a   Pollpeter, Molly J ^a   Nayak, Manasa K ^a   Staber, Janice M ^a   Chauhan, Anil K ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Brain ischemia reperfusion injury; Platelets; Thrombosis; Von Willebrand factor

Indexed keywords

FIBRIN; FIBRINOGEN; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAMTS13 PROTEIN, MOUSE; AUTACOID; CHLORIDE; FERRIC CHLORIDE; FERRIC ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAROTID ARTERY THROMBOSIS; CONTROLLED STUDY; ENDOTHELIUM CELL; FIBRIN DEPOSITION; IN VITRO STUDY; INFLAMMATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PATHOPHYSIOLOGY; POSTISCHEMIC THROMBO INFLAMMATION; PRIORITY JOURNAL; THROMBOCYTE; THROMBOSIS; WILD TYPE MOUSE; ANIMAL; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CAROTID ARTERY DISEASE; CEREBRAL ARTERY DISEASE; CHEMICALLY INDUCED; COMPARATIVE STUDY; DEFICIENCY; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; LASER; MALE; MESENTERIC BLOOD VESSEL OCCLUSION; METABOLISM; PATHOLOGY; PHENOTYPE; REPERFUSION INJURY; SIGNAL TRANSDUCTION; THROMBOCYTE TRANSFUSION; TIME FACTOR;

ADAMTS13 PROTEIN; ANIMALS; BLOOD PLATELETS; BONE MARROW TRANSPLANTATION; CAROTID ARTERY DISEASES; CHLORIDES; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FERRIC COMPOUNDS; GENETIC PREDISPOSITION TO DISEASE; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION; INFLAMMATION MEDIATORS; LASERS; MALE; MESENTERIC VASCULAR OCCLUSION; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; PHENOTYPE; PLATELET TRANSFUSION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; THROMBOSIS; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 84979713652     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307660     Document Type: Article

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