Therapeutic potential of Pterocarpus santalinus L.: An update

Pharmacognosy Reviews

Volumn 10, Issue 19, 2016, Pages 43-49

  Bulle, Saradamma ^a   Reddyvari, Hymavathi ^a   Nallanchakravarthula, Varadacharyulu ^a   Vaddi, Damodara Reddy ^b  

^a SRI KRISHNADEVARAYA UNIVERSITY   (India)

^b JNTU Oil Technological Research Institute Anantapur   (India)

Author keywords

Antioxidant activity; Oxidative stress; Phytocompounds; Pterocarpus santalinus

Indexed keywords

ALKALOID; ANALGESIC AGENT; ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARBOHYDRATE; FLAVONOID; GLYCOSIDE; PHENOL DERIVATIVE; PLANT MEDICINAL PRODUCT; PROTECTIVE AGENT; SAPONIN; TANNIN DERIVATIVE;

ANGIOGENESIS; ANTIBACTERIAL ACTIVITY; ANTIDIABETIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; CYTOTOXICITY; DIABETES MELLITUS; FREE RADICAL SCAVENGING ASSAY; GASTRIC MUCOSA; HUMAN; HYPOLIPEMIA; IN VITRO STUDY; IN VIVO STUDY; LIVER; LIVER PROTECTION; MALIGNANT NEOPLASTIC DISEASE; NERVOUS SYSTEM; NONHUMAN; PHARMACOGNOSY; PTEROCARPUS; PTEROCARPUS SANTALINUS; REVIEW; TRADITIONAL MEDICINE; WOUND HEALING;

EID: 84979656407     PISSN: 09737847     EISSN: 09762787     Source Type: Journal    
DOI: 10.4103/0973-7847.176575     Document Type: Review

References (70)

1. Cheng YL, Lee SC, Lin SZ, Chang WL, Chen YL, Tsai NM, et al. Anti-proliferative activity of Bupleurum scrozonerifolium in A549 human lung cancer cells in-vitro and in-vivo. Cancer Lett 2005;222:183-93.
2. Tan ML, Suaiman SF, Najimuddin N, Smian MR, Muhammad TS. Methanolic extract of Pereskia bleo (Kunth) DC. (Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line. J Ethnopharmacol 2005;96:287-94.
3. Halim ME, Misra A. The effect of aqueous extract of Pterocarus santalinus heartwood and vitamin E supplementation in streptozotocin-induced diabetic rats. J Med Plants Res 2011;5:398-409.
4. Ramawat KG, Goyal S. The Indian herbal drugs scenario in global perspectives. Bioact Molec Med Plant 2008;18:325-47.
5. Ajay Kumar M, Bansal P, Kumar S. Plants- herbal wealth as a potential source of ayurvedic drugs. Asian J Trad Med 2009;4:152-70.
6. Dhanabal P, Kannan SE, Bhojraj S. Protective and therapeutic effects of the Indian medicinal plant Pterocarpus santalinus on D-galactosamine-induced liver damage. Asian J Trad Med 2007;2:51-7.
7. Arunakumara KK, Walpola BC, Subasinghe S, Yoon M. Pterocarpus santalinus Linn. f. (Roth handgun): A Review of Its Botany, uses, Phytochemistry and Pharmacology. J Korean Soc Appl Biol Chem 2011;54:495-500.
8. Navada KK, Vittal RR. Ethnomedicinal value of Pterocarpus santalinus (Linn. f.), a Fabaceae member. Orient Pharm Exp Med 2014;14:313-7.
9. Manjunatha BK. Hepatoprotective activity of Pterocarpus santalinus L. f., an endangered plant. Indian J Pharmacol 2006;38:25-8.
10. Kwon HJ, Hong YK, Kim KH, Han CH, Cho SH, Choi JS, et al. Methanolic extract of Pterocarpus santalinus induces apoptosis in Hela cells. J Ethnopharmacol 2006;105:229-34.
11. Kondeti VK, Rao BK, Maddirala DR, Thur SK, Fatima SS, Kasetti RB, et al. Effect of Pterocarpus santalinus bark, on blood glucose, serum lipids, plasma insulin and hepatic carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats. Food Chem Toxicol 2010;48:1281-7.
12. Rastogi RP, Mehrotra BN. Compendium Indian Medicinal Plants. 1960-1969. Vol. I. New Delhi: Central Drug Institute Lucknow and Publication and Information Directorate; 1991. p. 437.
13. Arokiyaraj S, Martin S, Perinbam K, Marie AP, Beatrice V. Free radical scavenging activity and HPTLC finger print Pterocarpus santalinus L.-an in vitro study. Indian J Sci Technol 2008;1:1-3.
14. Narayan S, Devi RS, Srinivasan P, Shyamala Devi CS. Pterocarpus santalinus: A traditional herbal drug as a protectant against ibuprofen induced gastric ulcers. Phytother Res 2005;19:958-62.
15. Yoganarasimhan SN. Medicinal Plants of India, Tamil Nadu. Bangalore; Cyber Media: 2000. p. 63.
16. Kumar N, Seshadri TR. Triterpenoids of Pterocarpus santalinus constitution of a new leupenediol. Phytochem 1975;14:521-3.
17. Krishnaveni KS, Srinivasa Rao JV. A new isoflavone glucoside from Pterocarpus santalinus. Asian Nat Prod Res 2000;2:219-23.
18. Krishnaveni KS, Srinivasa Rao JV. A new triterpene from callus of Pterocarpus santalinus. Fitoter 2000b; 24:167-71.
19. Krishnaveni KS, Srinivasa Rao JV. An isoflavone from Pterocarpus santalinus. Phytochem 2000c; 53:605-6.
20. Cho JY, Park J, Kim PS, Yoo ES, Baik KU, Park MH. Savinin, a lignin from Pterocarpus santalinus inhibits tumor necrosis factor-alpha production and T-cell proliferation. Biol Pharm Bull 2001;24:167-74.
21. Kesari AN, Gupta RK, Watal G. Two aurone glycosides from heartwood of Pterocarpus santalinus. Phytochemistry 2004;65:3125-9.
22. Satheesh MA, Pari L. Effect of pterostilbene on lipids and lipid profiles in streptozotocin-nicotinamide induced type 2 diabetes mellitus. J Appl Biomed 2008;6:31-7.
23. Remsberg CM, Yanez JA, Ohgami Y, Vega-Villa KR, Rimando AM, Davies NM. Pharmacometrics of pterostilbene: Preclinical pharmacokinetics and metabolism, anticancer, anti-inflammatory, antioxidant and analgesic activity. Phytother Res 2008;22:169-79.
24. Ashidate K, Kawamura M, Mimura D, Tohda H, Miyazaki S, Teramoto T, et al. Gentisic acid, an aspirin metabolite, inhibits oxidation of low-density lipoprotein and the formation of cholesterol ester hydroperoxides in human plasma. Eur J Pharmacol 2005;513:173-9.
25. Khadem S, Marles RJ. Monocyclic phenolic acids; hydroxy- and polyhydroxybenzoic acids: Occurrence and recent bioactivity studies. Molecules 2010;15:7985-8005.
26. Wu SF, Chang FR, Wang SY, Hwang TL, Lee CL, Chen SL, et al. Anti-inflammatory and cytotoxic neoflavonoids and benzofurans from Pterocarpus santalinus. J Nat Prod 2011;74:989-96.
27. Fressco P, Borges F, Diniz C, Marques MP. New insights on the anticancer properties of dietary polyphenols. Med Res Rev 2006;26:747-66.
28. Spath E, Schlager J. Constituents of red sandalwood. II. Constitution of pterostilbene. Ber Dtsch Chem Ges1940;73:881.
29. McCormack D, McFadden D. Pterostilbene and cancer: Current review. J Surg Res 2012; 173:e53-61.
30. Ayres DC, Loike JD. Lignans: Chemical, Biological and Clinical Properties. Cambridge, United Kingdom; Cambridge University Press: 1990.
31. Cai YZ, Luo Q, Sun M, Corke H. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sci 2004;74:2157-84.
32. Wu SF, Hwang TL, Chen SL, Wu CC, Ohkoshi E, Lee KH, et al. Bioactive components from the heartwood of Pterocarpus santalinus. Bioorg Med Chem Lett 2011;21:5630-2.
33. Reddy L, Reddy G, Reddy RS, Reddy S, Reddy J. Characterization of Red sandalwood by ICP-MS Analysis, Optical absorption and EPR spectroscopic methods. Radiat Eff Defect Solids 2006;161:537-47.
34. Devi RK, Basha SK. Comparative amino acid profiling of pterocarpus santalinus and boswelia ovalifoliolata barks of Tirumala Hills, Eastern Ghats, Andhra Pradesh. Int J Basic App Chem Sci 2012;2:102-6.
35. Krishnamoorthy P, Stella J, Mohamed AJ, Anand M. Radical scavenging and antibacterial evaluation of Pterocarpus santalinus leaf in-vitro study. Int J Pharm Sci Res 2011;2:1204-8.
36. Kumar D. Anti-inflammatory, analgesic, and antioxidant activities of methanolic wood extract of Pterocarpus santalinus L. J Pharmacol Pharmacother 2011;2:200-2.
37. Achary JD, Ghaskadbi SS. Protective effect of pterostilbene against free radical mediated oxidative damage. BMC Complement Altern Med 2013;13:238.
38. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ. Global Burden of Disease and Risk Factors. New York; Oxford University Press: 2006.
39. Faremi TY, Suru SM, Fafunso MA, Obioha UE. Hepato-protective potentials of Phyllanthus amarus against ethanol-induced oxidative stress in rats. Food Cheml Toxicol 2008;46:2658-64.
40. Briskin DP. Medicinal plants and phytomedicines. Linking plant Biochemistry and Physiology to Human Health plant. Plant Physiol 2000;124:507-14.
41. Manjunatha BK. Antibacterial activity of Pterocarpus santalinus. Indian J Pharm Sci 2006;68:115-6.
42. Mishra MP, Padhy RN. In vitro antibacterial efficacy of 21 Indian timber-yielding plants against multidrug-resistant bacteria causing urinary tract infection. Osong Public Health Res Perspect 2013;4:347-57.
43. Dey SK, Chattopadhay S, Masanta NC. Antimicrobial activities of some medicinal plants of red and laterite zone of West Bengal, India. WJPPS 2014;3:719-34.
44. Gopinath K, Gowri S, Arumugam A. Phytosynthesis of silver nanoparticles using Pterocarpus santalinus leaf extract and their antibacterial properties. J Nanostruct Chem 2013;3:68-85.
45. Yamauchi S, Hayashi Y, Nakashima Y, Kirikihira T, Yamada K, Masuda T. Effect of benzylic oxygen on the antioxidant activity of phenolic lignans. J Nat Prod 2005;68:1459-70.
46. Narayan S, Veeraraghavan M, Devi CS. Pterocarpus santalinus: An In Vitro study on its anti-Helicobacter pylori effect. Phytother Res 2007;21:190-3.
47. Panayi GS, Lanchbury JS, Kingsley GH. The importance of the T cell in initiating and maintaining the chronic synovitis of rheumatoid arthritis. Arthritis Rheum 1992;35:729-35.
48. Nagaraju N, Rao KN. Folk-medicine for diabetes from Rayalaseema of Andhra Pradesh. Anc Sci Life 1989;9:31-5.
49. Nagaraju N, Prasad M, Gopalakrishna G, Rao KN. Blood sugar lowering effect of Pterocarpus santalinus (Red Sanders) wood extract in different rat models. Int J Pharmacogn 1991;29:141-4.
50. Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: From pathophysiology to prevention and management. Lancet 2011;378:169-81.
51. Kameswara Rao B, Giri R, Kesavulu MM, Apparao C. Effect of oral administration of bark extracts of Pterocarpus santalinus on blood glucose level in experimental animals. J Ethnopharmacol 2001;74:69-74.
52. Rao KB, Rajasekhar MD, Sreelatha A, Apparao C. Treatment of Diabetes Mellitus: Plant Drugs vs. Oral Hypoglycaemic Agents and Insulin. In Recent Progress in medicinal Plants. Vol. 14. ed. J.N.Govil, V.K.Singh, Khalil Ahmad. Biopharmaceuticals. LLC, Texas, USA: Studium Press. 2006. p. 279-96.
53. Huang WY, Cai YZ, Zhang Y. Natural phenolic compounds from medicinal herbs and dietary plants: Potential use for cancer prevention. Nutr Cancer 2010;62:1-20.
54. Mena S, Rodríguez ML, Ponsoda X, Estrela JM, Jäättela M, Ortega AL. Pterostilbene-induced tumor cytotoxicity: A lysosomal membrane permeabilization-dependent mechanism. PLoS One 2012;7:e44524.
55. Ding RB, Tian K, Huang LL, He CW, Jiang Y, Wang YT, et al. Herbal medicines for the prevention of alcoholic liver diseases: A review. J Ethnopharmacol 2012;144:457-65.
56. Manjunatha BK, Amit R, Priyadarshini P, Paul K. Lead findings from Pterocarpus santalinus with hepatoprotective potentials through in silico methods. Int J Pharma Sci and Res 2010;7:265-70.
57. Itoh A, Isoda K, Kondoh M, Kawase M, Kobayashi M, Tamesada M, et al. Hepatoprotective Effect of Syringic Acid and Vanillic Acid on Concanavalin A-Induced Liver Injury. Biol Pharm Bull 2009;32:1215-9.
58. Itoh A, Isoda K, Kondoh M, Kawase M, Watari A, Kobayashi, M, et al. Hepatoprotective effect of syringic acid and vanillic acid on CCl4-induced liver injury. Biol Pharm Bull 2010;33:983-7.
59. Narayana S, Devi RS, Devi CS. Role of Pterocarpus santalinus against mitochondrial dysfunction and membrane lipid changes induced by ulcerogens in rat gastric mucosa. Chem Biol Interact 2007;170:67-75.
60. Suanarunsawat T, Boonnak T, Na Ayutthaya WD, Thirawarapan S. Anti-hyperlipidemic and cardioprotective effects of Ocimum sanctum L. fixed oil in rats fed a high fat diet. J Basic Clin Physiol Pharmacol 2010;21:387-400.
61. Rimando AM, Nagmani R, Feller DR, Yokoyama W. Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamsters. J Agric Food Chem 2005;53:3403-7.
62. Riche DM, Riche KD, Blackshear CT, McEwen CL, Sherman JJ, Wofford MR, et al. Pterostilbene on metabolic parameters: A randomized, double-blind, and placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:459165.
63. Jadhav J, Mane A, Kanase A. Stimulatory effect of Pterocarpus santalinus on vasculogensis in chick chorioallantoic membrane (CAM). J Pharmacy Res 2012;5:208-11.
64. Biswas TK, Maity LN, Mukherjee B. Wound healing potential of Pterocarpus santalinus Linn: A Pharmacological evaluation. Int J Low Extrem Wounds 2004;3:143-50.
65. Sultana N, Akhter M, Khatoon Z. Nematicidal natural products from the aerial parts of Rubus niveus. Nat Prod Res 2010;24:407-15.
66. Chattopadhyay SK, Kumar TR, Maulik PR, Srivastava S, Garga A. Absolute configuration and anticancer activity of taxiresinol and related lignans of Taxas wallichiana. Bioorg Med Chem 2003;11:4945-8.
67. Kayser O, Kiderlen AF, Folkens U, Kolodziej H. In vitro leishmanicidal activity of aurones. Planta Med 1999;65:316-9.
68. Kayser O, Kiderlen AF, Brun B. In vitro activity of aurones against plasmodium falciparum strains K1 and NF54. Planta Med 2001;67:718-21.
69. Haschek WM, Wallig MA, Rousseaux C. Nomenclature: Terminology for morphologic alterations. In Fundamentals of Toxicologic Pathology. San Diego, CA, USA: Academic Press: 2010. p. 67-80.
70. Kirtikar KR, Basu BD. Indian Medicinal Plants. 2nd ed., Vol. 1. India: Bishen Singh Mahendra Pal Singh; 1980. p. 314.