Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis

Nature Communications

Volumn 7, Issue , 2016, Pages

  Shakeel, Shabih ^a   Westerhuis, Brenda M ^b   Domanska, Ausra ^a   Koning, Roman I ^c   Matadeen, Rishi ^d   Koster, Abraham J ^c   Bakker, Arjen Q ^b   Beaumont, Tim ^b   Wolthers, Katja C ^b   Butcher, Sarah J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; HUMAN MONOCLONAL ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; PLECONARIL; PROTEIN VP0; PROTEIN VP1; PROTEIN VP3; PROTEIN VP4; UNCLASSIFIED DRUG; VIRUS RNA; PROTEIN BINDING;

ANTIBODY; DRUG; GENETIC ANALYSIS; GENETIC STRUCTURE; GENOME; INFECTIOUS DISEASE; PROTEIN; VIRUS;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CONSERVED SEQUENCE; CRYOELECTRON MICROSCOPY; DRUG BINDING SITE; HUMAN PARECHOVIRUS; HUMAN PARECHOVIRUS 3; HYDROPHOBICITY; IMAGE RECONSTRUCTION; MOLECULAR STABILITY; NONHUMAN; PROTEIN RNA BINDING; RNA STRUCTURE; RNA TRANSPORT; VIRION; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS GENOME; VIRUS MORPHOLOGY; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOLECULAR MODEL; NEWBORN SEPSIS; PARECHOVIRUS; PHYSIOLOGY; PICORNAVIRUS INFECTION; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; VIROLOGY; X RAY CRYSTALLOGRAPHY;

HUMAN PARECHOVIRUS 3; MIRIDAE; PICORNAVIRIDAE;

AMINO ACID SEQUENCE; CAPSID; CAPSID PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEONATAL SEPSIS; PARECHOVIRUS; PICORNAVIRIDAE INFECTIONS; PROTEIN BINDING; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; VIRUS ASSEMBLY;

EID: 84979600171     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11387     Document Type: Article

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