Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduce dopamine signaling in the nucleus accumbens

International Journal of Neuropsychopharmacology

Volumn 19, Issue 5, 2016, Pages

  Rose, Jamie H ^a   Karkhanis, Anushree N ^b   Chen, Rong ^a   Gioia, Dominic ^a   Lopez, Marcelo F ^b,c   Becker, Howard C ^b,c,d   McCool, Brian A ^a   Jones, Sara R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Anxiety; Compulsion; Release; Uptake; Voltammetry

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; ALCOHOL; KAPPA OPIATE RECEPTOR; NORBINALTORPHIMINE; PYRAZOLE; DOPAMINE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST;

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR CHANGE; BRAIN SLICE; COMPULSION; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; DOPAMINE RELEASE; DOPAMINERGIC TRANSMISSION; EX VIVO STUDY; EXPOSURE; MALE; MARBLE BURYING TEST; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; SUPERSENSITIVITY; ALCOHOLISM; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DISEASE MODEL; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRINKING BEHAVIOR; DRUG EFFECTS; IN VITRO STUDY; METABOLISM; PATHOPHYSIOLOGY; PSYCHOLOGY; SYNAPTIC TRANSMISSION; WITHDRAWAL SYNDROME;

ALCOHOL DRINKING; ALCOHOL-INDUCED DISORDERS, NERVOUS SYSTEM; ANALGESICS, OPIOID; ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; COMPULSIVE BEHAVIOR; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; IN VITRO TECHNIQUES; MALE; MICE, INBRED C57BL; NARCOTIC ANTAGONISTS; NUCLEUS ACCUMBENS; RECEPTORS, OPIOID, KAPPA; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPTIC TRANSMISSION;

EID: 84979223223     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1093/ijnp/pyv127     Document Type: Article

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