Pharmacokinetic evidence for the long-lasting effect of nor-binaltorphimine, a potent kappa opioid receptor antagonist, in mice

Neuroscience Letters

Volumn 552, Issue , 2013, Pages 98-102

  Kishioka, Shiroh ^a   Kiguchi, Norikazu ^a   Kobayashi, Yuka ^a   Yamamoto, Chizuko ^a   Saika, Fumihiro ^a   Wakida, Naoki ^a   Ko, Mei Chuan ^b   Woods, James H ^b  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Brain content; HPLC ECD; Naloxone; Nor BNI; Pharmacokinetics

Indexed keywords

NALOXONE; NORBINALTORPHIMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; ELECTROCHEMICAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

BRAIN CONTENT; HPLC-ECD; NALOXONE; NOR-BNI; PHARMACOKINETICS;

ANIMALS; BRAIN; MALE; MICE; NALOXONE; NALTREXONE; NARCOTIC ANTAGONISTS; RECEPTORS, OPIOID, KAPPA; TIME FACTORS;

EID: 84884317140     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.07.040     Document Type: Article

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