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Volumn 3, Issue 2, 2014, Pages 129-137

LOXL2 catalytically inactive mutants mediate epithelial-to-mesenchymal transition

Author keywords

EMT; FAK; LOXL2; Lysyl oxidase; Src

Indexed keywords


EID: 84979009498     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.20146841     Document Type: Article
Times cited : (54)

References (40)
  • 2
    • 80054732350 scopus 로고    scopus 로고
    • Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src
    • Alt-Holland, A., Sowalsky, A. G., Szwec-Levin, Y., Shamis, Y., Hatch, H., Feig, L. A. and Garlick, J. A. (2011). Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src. J. Invest. Dermatol. 131, 2306-2315.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 2306-2315
    • Alt-Holland, A.1    Sowalsky, A.G.2    Szwec-Levin, Y.3    Shamis, Y.4    Hatch, H.5    Feig, L.A.6    Garlick, J.A.7
  • 6
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolós, V., Peinado, H., Pérez-Moreno, M. A., Fraga, M. F., Esteller, M. and Cano, A. (2003). The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J. Cell Sci. 116, 499-511.
    • (2003) J. Cell Sci. , vol.116 , pp. 499-511
    • Bolós, V.1    Peinado, H.2    Pérez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 8
    • 84867058802 scopus 로고    scopus 로고
    • LOXL2 in epithelial cell plasticity and tumor progression
    • Cano, A., Santamaría, P. G. and Moreno-Bueno, G. (2012). LOXL2 in epithelial cell plasticity and tumor progression. Future Oncol. 8, 1095-1108.
    • (2012) Future Oncol , vol.8 , pp. 1095-1108
    • Cano, A.1    Santamaría, P.G.2    Moreno-Bueno, G.3
  • 9
    • 0035232015 scopus 로고    scopus 로고
    • Lysyl oxidases: A novel multifunctional amine oxidase family
    • Csiszar, K. (2001). Lysyl oxidases: a novel multifunctional amine oxidase family. Prog. Nucleic Acid Res. Mol. Biol. 70, 1-32.
    • (2001) Prog. Nucleic Acid Res. Mol. Biol , vol.70 , pp. 1-32
    • Csiszar, K.1
  • 12
    • 0034695506 scopus 로고    scopus 로고
    • OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
    • Hata, A., Seoane, J., Lagna, G., Montalvo, E., Hemmati-Brivanlou, A. and Massagué, J. (2000). OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100, 229-240.
    • (2000) Cell , vol.100 , pp. 229-240
    • Hata, A.1    Seoane, J.2    Lagna, G.3    Montalvo, E.4    Hemmati-Brivanlou, A.5    Massagué, J.6
  • 14
    • 0033006297 scopus 로고    scopus 로고
    • Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily
    • Hohenester, E., Sasaki, T. and Timpl, R. (1999). Crystal structure of a scavenger receptor cysteine-rich domain sheds light on an ancient superfamily. Nat. Struct. Biol. 6, 228-232.
    • (1999) Nat. Struct. Biol , vol.6 , pp. 228-232
    • Hohenester, E.1    Sasaki, T.2    Timpl, R.3
  • 15
    • 67449108314 scopus 로고    scopus 로고
    • Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells
    • Hollosi, P., Yakushiji, J. K., Fong, K. S. K., Csiszar, K. and Fong, S. F. T. (2009) Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells. Int. J. Cancer 125, 318-327.
    • (2009) Int. J. Cancer , vol.125 , pp. 318-327
    • Hollosi, P.1    Yakushiji, J.K.2    Fong, K.S.K.3    Csiszar, K.4    Fong, S.F.T.5
  • 16
    • 0033617456 scopus 로고    scopus 로고
    • The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues
    • Jourdan-Le Saux, C., Tronecker, H., Bogic, L., Bryant-Greenwood, G. D., Boyd, C. D. and Csiszar, K. (1999). The LOXL2 gene encodes a new lysyl oxidase-like protein and is expressed at high levels in reproductive tissues. J. Biol. Chem. 274, 12939-12944.
    • (1999) J. Biol. Chem. , vol.274 , pp. 12939-12944
    • Jourdan-Le Saux, C.1    Tronecker, H.2    Bogic, L.3    Bryant-Greenwood, G.D.4    Boyd, C.D.5    Csiszar, K.6
  • 17
    • 80051663780 scopus 로고    scopus 로고
    • Identification of the copper-binding ligands of lysyl oxidase
    • Lopez, K. M. and Greenaway, F. T. (2011). Identification of the copper-binding ligands of lysyl oxidase. J. Neural Transm. 118, 1101-1109.
    • (2011) J. Neural Transm. , vol.118 , pp. 1101-1109
    • Lopez, K.M.1    Greenaway, F.T.2
  • 18
    • 33750437433 scopus 로고    scopus 로고
    • Lysyl oxidase: An oxidative enzyme and effector of cell function
    • Lucero, H. A. and Kagan, H. M. (2006). Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell. Mol. Life Sci. 63, 2304-2316.
    • (2006) Cell. Mol. Life Sci , vol.63 , pp. 2304-2316
    • Lucero, H.A.1    Kagan, H.M.2
  • 19
    • 84856283525 scopus 로고    scopus 로고
    • The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation
    • Lugassy, J., Zaffryar-Eilot, S., Soueid, S., Mordoviz, A., Smith, V., Kessler, O. and Neufeld, G. (2012). The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation. J. Biol. Chem. 287, 3541-3549.
    • (2012) J. Biol. Chem. , vol.287 , pp. 3541-3549
    • Lugassy, J.1    Zaffryar-Eilot, S.2    Soueid, S.3    Mordoviz, A.4    Smith, V.5    Kessler, O.6    Neufeld, G.7
  • 20
    • 80053612895 scopus 로고    scopus 로고
    • The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis
    • Martínez, V. G., Moestrup, S. K., Holmskov, U., Mollenhauer, J. and Lozano, F. (2011). The conserved scavenger receptor cysteine-rich superfamily in therapy and diagnosis. Pharmacol. Rev. 63, 967-1000.
    • (2011) Pharmacol. Rev , vol.63 , pp. 967-1000
    • Martínez, V.G.1    Moestrup, S.K.2    Holmskov, U.3    Mollenhauer, J.4    Lozano, F.5
  • 26
    • 84866325625 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition under control: Global programs to regulate epithelial plasticity
    • Nieto, M. A. and Cano, A. (2012). The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity. Semin. Cancer Biol. 22, 361-368.
    • (2012) Semin. Cancer Biol , vol.22 , pp. 361-368
    • Nieto, M.A.1    Cano, A.2
  • 27
    • 0037081128 scopus 로고    scopus 로고
    • A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples
    • Palamakumbura, A. H. and Trackman, P. C. (2002). A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples. Anal. Biochem. 300, 245-251.
    • (2002) Anal. Biochem , vol.300 , pp. 245-251
    • Palamakumbura, A.H.1    Trackman, P.C.2
  • 28
    • 0346363757 scopus 로고    scopus 로고
    • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/ HDAC2 complex
    • Peinado, H., Ballestar, E., Esteller, M. and Cano, A. (2004). Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/ HDAC2 complex. Mol. Cell. Biol. 24, 306-319.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 306-319
    • Peinado, H.1    Ballestar, E.2    Esteller, M.3    Cano, A.4
  • 30
    • 29244463349 scopus 로고    scopus 로고
    • Switching on-off Snail: LOXL2 versus GSK3beta
    • Peinado, H., Portillo, F. and Cano, A. (2005b). Switching on-off Snail: LOXL2 versus GSK3beta. Cell Cycle 4, 1749-1752.
    • (2005) Cell Cycle , vol.4 , pp. 1749-1752
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 31
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat
    • Peinado, H., Olmeda, D. and Cano, A. (2007). Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat. Rev. Cancer 7, 415-428.
    • (2007) Rev. Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 34
    • 70349980883 scopus 로고    scopus 로고
    • Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway
    • Peng, L., Ran, Y. L., Hu, H., Yu, L., Liu, Q., Zhou, Z., Sun, Y. M., Sun, L. C., Pan, J., Sun, L. X. et al. (2009). Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway. Carcinogenesis 30, 1660-1669.
    • (2009) Carcinogenesis , vol.30 , pp. 1660-1669
    • Peng, L.1    Ran, Y.L.2    Hu, H.3    Yu, L.4    Liu, Q.5    Zhou, Z.6    Sun, Y.M.7    Sun, L.C.8    Pan, J.9    Sun, L.X.10
  • 35
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • Polyak, K. and Weinberg, R. A. (2009). Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat. Rev. Cancer 9, 265-273.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 36
    • 0030888680 scopus 로고    scopus 로고
    • Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence
    • Saito, H., Papaconstantinou, J., Sato, H. and Goldstein, S. (1997). Regulation of a novel gene encoding a lysyl oxidase-related protein in cellular adhesion and senescence. J. Biol. Chem. 272, 8157-8160.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8157-8160
    • Saito, H.1    Papaconstantinou, J.2    Sato, H.3    Goldstein, S.4
  • 37
    • 77951184829 scopus 로고    scopus 로고
    • Cellular functions of FAK kinases: Insight into molecular mechanisms and novel functions
    • Schaller, M. D. (2010). Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions. J. Cell Sci. 123, 1007-1013.
    • (2010) J. Cell Sci. , vol.123 , pp. 1007-1013
    • Schaller, M.D.1
  • 39
    • 70450198396 scopus 로고    scopus 로고
    • Epithelialmesenchymal transitions in development and disease
    • Thiery, J. P., Acloque, H., Huang, R. Y. and Nieto, M. A. (2009). Epithelialmesenchymal transitions in development and disease. Cell 139, 871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 40
    • 84874303095 scopus 로고    scopus 로고
    • Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells
    • Xu, L., Go, E. P., Finney, J., Moon, H., Lantz, M., Rebecchi, K., Desaire, H. and Mure, M. (2013). Post-translational modifications of recombinant human lysyl oxidase-like 2 (rhLOXL2) secreted from Drosophila S2 cells. J. Biol. Chem. 288, 5357-5363.
    • (2013) J. Biol. Chem. , vol.288 , pp. 5357-5363
    • Xu, L.1    Go, E.P.2    Finney, J.3    Moon, H.4    Lantz, M.5    Rebecchi, K.6    Desaire, H.7    Mure, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.