Destined to develop NAFLD? The predictors of fatty liver from birth to adulthood

Journal of Hepatology

Volumn 65, Issue 4, 2016, Pages 668-670

  Valenti, Luca ^a,b   Romeo, Stefano ^c,d  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY HOSPITAL OF VERONA   (Italy)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

^d UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

Author keywords

Genetics; Non alcoholic fatty liver disease; Risk factor

Indexed keywords

ADULTHOOD; BIRTH; BODY MASS; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA MODIFICATION; EDITORIAL; ENVIRONMENTAL FACTOR; EPIDEMIC; EPIGENETICS; FATTY LIVER; GENE MUTATION; GENETIC RISK; GENETIC VARIATION; HUMAN; NONALCOHOLIC FATTY LIVER; OBESITY; PREDICTION; PRIORITY JOURNAL; SEDENTARY LIFESTYLE; RISK FACTOR;

HUMANS; NON-ALCOHOLIC FATTY LIVER DISEASE; OBESITY; RISK FACTORS;

EID: 84978795793     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2016.06.010     Document Type: Editorial

References (21)

1. [1] Nobili, V., Svegliati-Baroni, G., Alisi, A., Miele, L., Valenti, L., Vajro, P., A 360-degree overview of paediatric Nafld: recent insights. J Hepatol 58 (2013), 1218–1229.
2. [2] Dongiovanni, P., Valenti, L., Genetics of nonalcoholic fatty liver disease. Metabolism 65 (2015), 1026–1037.
3. [3] Romeo, S., Kozlitina, J., Xing, C., Pertsemlidis, A., Cox, D., Pennacchio, L.A., et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 40 (2008), 1461–1465.
4. [4] Kozlitina, J., Smagris, E., Stender, S., Nordestgaard, B.G., Zhou, H.H., Tybjaerg-Hansen, A., et al. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 46 (2014), 352–356.
5. [5] Mancina, R.M., Dongiovanni, P., Petta, S., Pingitore, P., Meroni, M., Rametta, R., et al. The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent. Gastroenterology, 150, 2016, e1216.
6. [6] Dongiovanni, P., Romeo, S., Valenti, L., Genetic factors in the pathogenesis of nonalcoholic fatty liver and steatohepatitis. Biomed Res Int, 2015, 2015, 460190.
7. [7] Dongiovanni, P., Donati, B., Fares, R., Lombardi, R., Mancina, R.M., Romeo, S., et al. PNPLA3 I148M polymorphism and progressive liver disease. World J Gastroenterol 19 (2013), 6969–6978.
8. [8] Sun, C., Fan, J.G., Qiao, L., Potential epigenetic mechanism in non-alcoholic Fatty liver disease. Int J Mol Sci 16 (2015), 5161–5179.
9. [9] Bruce, K.D., Cagampang, F.R., Argenton, M., Zhang, J., Ethirajan, P.L., Burdge, G.C., et al. Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression. Hepatology 50 (2009), 1796–1808.
10. [10] Dudley, K.J., Sloboda, D.M., Connor, K.L., Beltrand, J., Vickers, M.H., Offspring of mothers fed a high fat diet display hepatic cell cycle inhibition and associated changes in gene expression and DNA methylation. PLoS One, 6, 2011, e21662.
11. [11] Suomela, E., Oikonen, M., Pitkänen, N., Ahola-Olli, A., Virtanen, J., Parkkola, R., et al. Childhood predictors of adult fatty liver. The cardiovascular risk in young Finns study. J Hepatol 65 (2016), 784–790.
12. [12] Suomela, E., Oikonen, M., Virtanen, J., Parkkola, R., Jokinen, E., Laitinen, T., et al. Prevalence and determinants of fatty liver in normal-weight and overweight young adults. The Cardiovascular Risk in Young Finns Study. Ann Med 47 (2015), 40–46.
13. [13] Nobili, V., Marcellini, M., Marchesini, G., Vanni, E., Manco, M., Villani, A., et al. Intrauterine growth retardation, insulin resistance, and nonalcoholic fatty liver disease in children. Diabetes Care 30 (2007), 2638–2640.
14. [14] Breij, L.M., Kerkhof, G.F., Hokken-Koelega, A.C., Accelerated infant weight gain and risk for nonalcoholic fatty liver disease in early adulthood. J Clin Endocrinol Metab 99 (2014), 1189–1195.
15. [15] Dongiovanni, P., Lanti, C., Riso, P., Valenti, L., Nutritional therapy for nonalcoholic fatty liver disease. J Nutr Biochem 29 (2016), 1–11.
16. [16] Gaggini, M., Morelli, M., Buzzigoli, E., DeFronzo, R.A., Bugianesi, E., Gastaldelli, A., Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease. Nutrients 5 (2013), 1544–1560.
17. [17] Hong, H.C., Hwang, S.Y., Choi, H.Y., Yoo, H.J., Seo, J.A., Kim, S.G., et al. Relationship between sarcopenia and nonalcoholic fatty liver disease: the Korean Sarcopenic Obesity Study. Hepatology 59 (2014), 1772–1778.
18. [18] Kelley, C.E., Brown, A.J., Diehl, A.M., Setji, T.L., Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome. World J Gastroenterol 20 (2014), 14172–14184.
19. [19] Dongiovanni, P., Fracanzani, A.L., Fargion, S., Valenti, L., Iron in fatty liver and in the metabolic syndrome: a promising therapeutic target. J Hepatol 55 (2011), 920–932.
20. [20] Bertolotti, M., Lonardo, A., Mussi, C., Baldelli, E., Pellegrini, E., Ballestri, S., et al. Nonalcoholic fatty liver disease and aging: epidemiology to management. World J Gastroenterol 20 (2014), 14185–14204.
21. [21] Ryu, S., Suh, B.S., Chang, Y., Kwon, M.J., Yun, K.E., Jung, H.S., et al. Menopausal stages and non-alcoholic fatty liver disease in middle-aged women. Eur J Obstet Gynecol Reprod Biol 190 (2015), 65–70.