Combination of radiotherapy and vaccination overcome checkpoint blockade resistance

Oncotarget

Volumn 7, Issue 28, 2016, Pages 43039-43051

  Zheng, Wenxin ^a   Skowron, Kinga B ^a   Namm, Jukes P ^a,b   Burnette, Byron ^a   Fernandez, Christian ^a   Arina, Ainhoa ^a   Liang, Hua ^a   Spiotto, Michael T ^a   Posner, Mitchell C ^a   Fu, Yang Xin ^a,c   Weichselbaum, Ralph R ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b LOMA LINDA UNIVERSITY HEALTH   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Checkpoint blockade; Radiation therapy; T cell infiltration; Tumor model; Vaccination

Indexed keywords

CANCER VACCINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; PROGRAMMED DEATH 1 LIGAND 1; RANTES; CD274 PROTEIN, MOUSE; CHEMOKINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER IMMUNIZATION; CANCER INHIBITION; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; HUMAN; MOUSE; NONHUMAN; PANCREAS CANCER; PROTEIN EXPRESSION; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; TUMOR REGRESSION; TUMOR XENOGRAFT; ANIMAL; C57BL MOUSE; EXPERIMENTAL NEOPLASM; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; METABOLISM; MULTIMODALITY CANCER THERAPY; PANCREAS TUMOR; PROCEDURES; RADIOTHERAPY; SURVIVAL ANALYSIS; TRANSGENIC MOUSE; TUMOR CELL LINE; VACCINATION;

ANIMALS; B7-H1 ANTIGEN; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CHEMOKINES; COMBINED MODALITY THERAPY; GENE EXPRESSION REGULATION, NEOPLASTIC; IMMUNOTHERAPY; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOPLASMS, EXPERIMENTAL; PANCREATIC NEOPLASMS; RADIOTHERAPY; SURVIVAL ANALYSIS; VACCINATION;

EID: 84978665423     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9915     Document Type: Article

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