Association between subclinical malaria infection and inflammatory host response in a pre-elimination setting

PLoS ONE

Volumn 11, Issue 7, 2016, Pages

  Peto, Thomas J ^a,b   Tripura, Rupam ^a   Lee, Sue J ^a,b   Althaus, Thomas ^a   Dunachie, Susanna ^a,b   Nguon, Chea ^c   Dhorda, Mehul ^a,b   Promnarate, Cholrawee ^a   Chalk, Jeremy ^a,b   Imwong, Mallika ^a   Von Seidlein, Lorenz ^a,b   Day, Nicholas P ^a,b   Dondorp, Arjen M ^a,b   White, Nicholas J ^a,b   Lubell, Yoel ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c National Center for Parasitology Entomology and Malaria Control   (Cambodia)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN;

ADULT; ARTICLE; ASYMPTOMATIC INFECTION; BLOOD SAMPLING; CAMBODIA; CASE CONTROL STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; FEMALE; HIGH VOLUME ULTRA SENSITIVE POLYMERASE CHAIN REACTION; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; PARASITE DENSITY; PARASITEMIA; PLASMODIUM VIVAX MALARIA; POLYMERASE CHAIN REACTION; POPULATION DENSITY; PROTEIN BLOOD LEVEL; RURAL POPULATION; ADOLESCENT; CHILD; IMMUNOLOGY; INFANT; INFLAMMATION; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PRESCHOOL CHILD;

ADOLESCENT; ADULT; ASYMPTOMATIC INFECTIONS; C-REACTIVE PROTEIN; CAMBODIA; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFLAMMATION; MALARIA, FALCIPARUM; MALARIA, VIVAX; MALE; PARASITEMIA; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; POLYMERASE CHAIN REACTION;

EID: 84978647643     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0158656     Document Type: Article

References (31)

1. Imwong M, Nguyen TN, Tripura R, Peto TJ, Lee SJ, Lwin KM, et al. The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam. Malaria journal. 2015; 14:381. doi: 10.1186/s12936-015-0906-x PMID: 26424000; PubMed Central PMCID: PMCPMC4590703.
2. Sluydts V, Heng S, Coosemans M, Van Roey K, Gryseels C, Canier L, et al. Spatial clustering and risk factors of malaria infections in Ratanakiri Province, Cambodia. Malaria journal. 2014; 13:387. Epub 2014/10/02. doi: 10.1186/1475-2875-13-387 PMID: 25269827; PubMed Central PMCID: PMC4190307.
3. Bosman P, Stassijns J, Nackers F, Canier L, Kim N, Khim S, et al. Plasmodium prevalence and artemisinin-resistant falciparum malaria in Preah Vihear Province, Cambodia: a cross-sectional population-based study. Malaria journal. 2014; 13:394. Epub 2014/10/08. doi: 10.1186/1475-2875-13-394 PMID: 25288380; PubMed Central PMCID: PMC4200124.
4. Narayanasamy K, Chery L, Basu A, Duraisingh MT, Escalante A, Fowble J, et al. Malaria evolution in South Asia: Knowledge for control and elimination. Acta tropica. 2012; 121(3):256-66. doi: 10.1016/j.actatropica.2012.01.008 PMID: 22266213
5. Imwong M, Stepniewska K, Tripura R, Peto TJ, Lwin KM, Vihokhern B, et al. The numerical distributions of parasite densities in asymptomatic malaria. Journal of Infectious Diseases. 2015:jiv596.
6. Chen I, Clarke SE, Gosling R, Hamainza B, Killeen G, Magill A, et al. "Asymptomatic" Malaria: A Chronic and Debilitating Infection That Should Be Treated. PLoS Med. 2016; 13(1):e1001942. doi: 10.1371/journal.pmed.1001942 PMID: 26783752.
7. Imrie H, Fowkes FJ, Michon P, Tavul L, Reeder JC, Day KP. Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea. The American journal of tropical medicine and hygiene. 2007; 76(2):280-4. PMID: 17297036.
8. Eriksson UK, van Bodegom D, May L, Boef AG, Westendorp RG. Low C-reactive protein levels in a traditional West-African population living in a malaria endemic area. PLoS One. 2013; 8(7).
9. de Mast Q, Brouwers J, Syafruddin D, Bousema T, Baidjoe AY, de Groot PG, et al. Is asymptomatic malaria really asymptomatic? Hematological, vascular and inflammatory effects of asymptomatic malaria parasitemia. J Infect. 2015; 71(5):587-96. doi: 10.1016/j.jinf.2015.08.005 PMID: 26304688.
10. Ridker PM. Inflammatory biomarkers and risks of myocardial infarction, stroke, diabetes, and total mortality: implications for longevity. Nutrition reviews. 2007; 65(suppl 3):S253-S9.
11. Wu AH. Tietz clinical guide to laboratory tests: Elsevier Health Sciences; 2006.
12. Macy EM, Hayes TE, Tracy RP. Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications. Clin Chem. 1997; 43(1):52-8. PMID: 8990222.
13. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation. 2003; 107(3):363-9. PMID: 12551853
14. Yousuf O, Mohanty BD, Martin SS, Joshi PH, Blaha MJ, Nasir K, et al. High-sensitivity C-reactive protein and cardiovascular disease: a resolute belief or an elusive link? Journal of the American College of Cardiology. 2013; 62(5):397-408. doi: 10.1016/j.jacc.2013.05.016 PMID: 23727085
15. Koenig W, Khuseyinova N, Baumert J, Meisinger C. Prospective study of high-sensitivity C-reactive protein as a determinant of mortality: results from the MONICA/KORA Augsburg Cohort Study, 1984-1998. Clinical chemistry. 2008; 54(2):335-42. PMID: 18156284
16. Diez-Padrisa N, Bassat Q, Machevo S, Quinto L, Morais L, Nhampossa T, et al. Procalcitonin and C-reactive protein for invasive bacterial pneumonia diagnosis among children in Mozambique, a malaria-endemic area. PLoS One. 2010; 5(10):e13226. Epub 2010/10/27. doi: 10.1371/journal.pone.0013226 PMID: 20976241; PubMed Central PMCID: PMC2954814.
17. Lubell Y, Blacksell S, Dunachie S, Tanganuchitcharnchai A, Watthanaworawit W, Paris D, et al. Performance of C-Reactive Protein and Procalcitonin to distinguish Viral from Bacterial and Malarial Causes of Fever in Southeast Asia. BMC Infectious Diseases. 2015; doi: 10.1186/s12879-015-1272-6
18. Pelkonen T, Albino A, Roine I, Bernardino L, Peltola H. C-reactive protein in children with malaria in Luanda, Angola: a prospective study. Trans R Soc Trop Med Hyg. 2015; 109(8):535-7. doi: 10.1093/trstmh/trv046 PMID: 26065879.
19. Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006; 124(4):823-35. doi: 10.1016/j.cell.2006.02.016 PMID: 16497591.
20. Schottenfeld D, Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J Clin. 2006; 56(2):69-83. PMID: 16514135.
21. Kuper H, Adami HO, Trichopoulos D. Infections as a major preventable cause of human cancer. J Intern Med. 2000; 248(3):171-83. PMID: 10971784.
22. Yeo TW, Lampah DA, Tjitra E, Piera K, Gitawati R, Kenangalem E, et al. Greater endothelial activation, Weibel-Palade body release and host inflammatory response to Plasmodium vivax, compared with Plasmodium falciparum: a prospective study in Papua, Indonesia. J Infect Dis. 2010; 202(1):109-12. doi: 10.1086/653211 PMID: 20497057; PubMed Central PMCID: PMC4313368.
23. Maude RJ, Nguon C, Ly P, Bunkea T, Ngor P, Canavati de la Torre SE, et al. Spatial and temporal epidemiology of clinical malaria in Cambodia 2004-2013. Malaria journal. 2014; 13:385. Epub 2014/10/01. doi: 10.1186/1475-2875-13-385 PMID: 25266007.
24. Cox J, Sovannaroth S, Dy Soley L, Ngor P, Mellor S, Roca-Feltrer A. Novel approaches to risk stratification to support malaria elimination: an example from Cambodia. Malaria journal. 2014; 13:371. Epub 2014/09/23. doi: 10.1186/1475-2875-13-371 PMID: 25233886; PubMed Central PMCID: PMC4177243.
25. Yeung S, Lawford HL, Tabernero P, Nguon C, van Wyk A, Malik N, et al. Quality of antimalarials at the epicenter of antimalarial drug resistance: results from an overt and mystery client survey in cambodia. The American journal of tropical medicine and hygiene. 2015; 92(6 Suppl):39-50. doi: 10.4269/ajtmh.14-0391 PMID: 25897063.
26. CNM. National Treatment Guidelines for Malaria. Cambodian National Malaria Control Programme, 2014.
27. Lim S, Yasuoka J, Poudel KC, Ly P, Nguon C, Jimba M. Promoting community knowledge and action for malaria control in rural Cambodia: potential contributions of Village Malaria Workers. BMC research notes. 2012; 5:405. Epub 2012/08/07. doi: 10.1186/1756-0500-5-405 PMID: 22863397; PubMed Central PMCID: PMC3475080.
28. von Seidlein L, Dondorp A. Fighting fire with fire: mass antimalarial drug administrations in an era of antimalarial resistance. Expert review of anti-infective therapy. 2015; 13(6):715-30. doi: 10.1586/14787210.2015.1031744 PMID: 25831482.
29. Imwong M, Hanchana S, Malleret B, Rénia L, Day NP, Dondorp A, et al. High-throughput ultrasensitive molecular techniques for quantifying low-density malaria parasitemias. Journal of clinical microbiology. 2014; 52(9):3303-9. doi: 10.1128/JCM.01057-14 PMID: 24989601
30. Imwong M, Hanchana S, Malleret B, Renia L, Day NP, Dondorp A, et al. High-throughput ultrasensitive molecular techniques for quantifying low-density malaria parasitemias. Journal of clinical microbiology. 2014; 52(9):3303-9. Epub 2014/07/06. doi: 10.1128/JCM.01057-14 PMID: 24989601; PubMed Central PMCID: PMC4313154.
31. Mugittu K, Adjuik M, Snounou G, Ntoumi F, Taylor W, Mshinda H, et al. Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: adjustment of parasitological outcomes and assessment of genotyping effectiveness. Trop Med Int Health. 2006; 11(9):1350-9. doi: 10.1111/j.1365-3156.2006.01688.x PMID: 16930256.