Molecular genotyping to distinguish between recrudescents and new infections in treatment trials of Plasmodium falciparum malaria conducted in Sub-Saharan Africa: Adjustment of parasitological outcomes and assessment of genotyping effectiveness

Tropical Medicine and International Health

Volumn 11, Issue 9, 2006, Pages 1350-1359

  Mugittu, Kefas ^a,g   Adjuik, Martin ^b   Snounou, Georges ^c   Ntoumi, Francine ^d   Taylor, Walter ^e   Mshinda, Hassan ^a   Olliaro, Piero ^e,f   Beck, Hans Peter ^g  

^a IFAKARA HEALTH INSTITUTE   (Tanzania)

^b NAVRONGO HEALTH RESEARCH CENTRE   (Ghana)

^c INSTITUT PASTEUR   (France)

^d ALBERT SCHWEITZER HOSPITAL   (Gabon)

^e WORLD HEALTH ORGANIZATION   (Switzerland)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Drug trials; Molecular genotyping; PCR adjusted antimalarial treatment outcomes

Indexed keywords

AMODIAQUINE; ARTESUNATE; CHLOROQUINE; GLUTAMATE RICH PROTEIN; MEROZOITE SURFACE PROTEIN 1; MEROZOITE SURFACE PROTEIN 2; PROTEIN; PYRIMETHAMINE; SULFADOXINE; UNCLASSIFIED DRUG;

CHILD HEALTH; DISEASE TREATMENT; GENOTYPE; INFECTIOUS DISEASE; MALARIA; PARASITOLOGY; WORLD HEALTH ORGANIZATION;

AFRICA; ARTICLE; CHILDHOOD DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GENE LOCUS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MONOTHERAPY; PARASITEMIA; PERFORMANCE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; TREATMENT FAILURE; TREATMENT OUTCOME;

AFRICA SOUTH OF THE SAHARA; ANIMALS; ANTIGENS, PROTOZOAN; ANTIMALARIALS; ARTEMISININS; CHILD; GENOTYPE; HUMANS; MALARIA, FALCIPARUM; MEROZOITE SURFACE PROTEIN 1; PARASITEMIA; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RANDOMIZED CONTROLLED TRIALS; RECURRENCE; SESQUITERPENES; TREATMENT OUTCOME;

AFRICA; SUB-SAHARAN AFRICA;

PLASMODIUM FALCIPARUM;

EID: 33747890438     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2006.01688.x     Document Type: Article

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