Comparison of the efficacies of parenteral iron sucrose and oral iron sulfate for anemic patients with inflammatory bowel disease in korea

Gut and Liver

Volumn 10, Issue 4, 2016, Pages 562-568

  Han, Yoo Min ^a   Yoon, Hyuk ^b   Shin, Cheol Min ^b   Koh, Seong Joon ^c   Im, Jong Pil ^a   Kim, Byeong Gwan ^c   Kim, Joo Sung ^a   Jung, Hyun Chae ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University Bundang Hospital   (South Korea)

^c Seoul National University Boramae Hospital   (South Korea)

Author keywords

Anemia, iron deficiency; Colitis, ulcerative; Crohn disease; Inflammatory bowel diseases; Parenteral iron

Indexed keywords

FERROUS SULFATE; HEMOGLOBIN; IRON SACCHARATE; ANTIANEMIC AGENT; FERRIC ION; FERRIC OXIDE, SACCHARATED; FERROUS ION; SACCHARIC ACID;

ADULT; ANEMIA; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DRUG EFFICACY; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; INFLAMMATORY BOWEL DISEASE; MAJOR CLINICAL STUDY; MALE; RETROSPECTIVE STUDY; TREATMENT DURATION; ULCERATIVE COLITIS; ADOLESCENT; ANEMIA, IRON-DEFICIENCY; CLINICAL TRIAL; COMPARATIVE STUDY; COMPLICATION; DIETARY SUPPLEMENT; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PARENTERAL DRUG ADMINISTRATION; SOUTH KOREA; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; ANEMIA, IRON-DEFICIENCY; DIETARY SUPPLEMENTS; FEMALE; FERRIC COMPOUNDS; FERROUS COMPOUNDS; GLUCARIC ACID; HEMATINICS; HUMANS; INFLAMMATORY BOWEL DISEASES; INFUSIONS, PARENTERAL; MALE; REPUBLIC OF KOREA; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84978514942     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl15373     Document Type: Article

References (25)

1. Schreiber S, Howaldt S, Schnoor M, et al. Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease. N Engl J Med 1996;334:619-623.
2. Cucino C, Sonnenberg A. Cause of death in patients with inflammatory bowel disease. Inflamm Bowel Dis 2001;7:250-255.
3. Pizzi LT, Weston CM, Goldfarb NI, et al. Impact of chronic conditions on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis 2006;12:47-52.
4. Wells CW, Lewis S, Barton JR, Corbett S. Effects of changes in hemoglobin level on quality of life and cognitive function in inflammatory bowel disease patients. Inflamm Bowel Dis 2006;12:123-130.
5. Cronin CC, Shanahan F. Anemia in patients with chronic inflammatory bowel disease. Am J Gastroenterol 2001;96:2296-2298.
6. Kulnigg S, Gasche C. Systematic review: managing anaemia in Crohn's disease. Aliment Pharmacol Ther 2006;24:1507-1523.
7. Ott C, Liebold A, Takses A, Strauch UG, Obermeier F. High prevalence but insufficient treatment of iron-deficiency anemia in patients with inflammatory bowel disease: results of a populationbased cohort. Gastroenterol Res Pract 2012;2012:595970.
8. Gisbert JP, Bermejo F, Pajares R, et al. Oral and intravenous iron treatment in inflammatory bowel disease: hematological response and quality of life improvement. Inflamm Bowel Dis 2009;15:1485-1491.
9. Danese S, Hoffman C, Vel S, et al. Anaemia from a patient perspective in inflammatory bowel disease: results from the European Federation of Crohn's and Ulcerative Colitis Association's online survey. Eur J Gastroenterol Hepatol 2014;26:1385-1391.
10. Lee TW, Kolber MR, Fedorak RN, van Zanten SV. Iron replacement therapy in inflammatory bowel disease patients with iron deficiency anemia: a systematic review and meta-analysis. J Crohns Colitis 2012;6:267-275.
11. Avni T, Bieber A, Steinmetz T, Leibovici L, Gafter-Gvili A. Treatment of anemia in inflammatory bowel disease: systematic review and meta-analysis. PLoS One 2013;8:e75540.
12. Gasche C, Berstad A, Befrits R, et al. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases. Inflamm Bowel Dis 2007;13:1545-1553.
13. Dignass AU, Gasche C, Bettenworth D, et al. European consensus on the diagnosis and management of iron deficiency and anaemia in inflammatory bowel diseases. J Crohns Colitis 2015;9:211-222.
14. Kulnigg S, Stoinov S, Simanenkov V, et al. A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: the ferric carboxymaltose (FERINJECT) randomized controlled trial. Am J Gastroenterol 2008;103:1182-1192.
15. Lindgren S, Wikman O, Befrits R, et al. Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: a randomized, controlled, evaluatorblind, multicentre study. Scand J Gastroenterol 2009;44:838-845.
16. Schröder O, Mickisch O, Seidler U, et al. Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease: a randomized, controlled, open-label, multicenter study. Am J Gastroenterol 2005;100:2503-2509.
17. Erichsen K, Ulvik RJ, Nysaeter G, et al. Oral ferrous fumarate or intravenous iron sucrose for patients with inflammatory bowel disease. Scand J Gastroenterol 2005;40:1058-1065.
18. Kim YJ. Intravenous iron and oral iron treatment in anemia of inflammatory bowel disease. Intest Res 2013;11:227-228.
19. Ye BD, Jang BI, Jeen YT, et al. Diagnostic guideline of Crohn's disease. Korean J Gastroenterol 2009;53:161-176.
20. Choi CH, Jung SA, Lee BI, et al. Diagnostic guideline of ulcerative colitis. Korean J Gastroenterol 2009;53:145-160.
21. Geisser P, Burckhardt S. The pharmacokinetics and pharmacodynamics of iron preparations. Pharmaceutics 2011;3:12-33.
22. Kaushansky K, Lichtman MA, Beutler E, Kipps TJ, Seligsohn U, Prchal JT. Williams Hematology. 8th ed. New York: McGraw-Hill Education LLC, 2010.
23. Naito Y, Tsujino T, Matsumoto M, Sakoda T, Ohyanagi M, Masuyama T. Adaptive response of the heart to long-term anemia induced by iron deficiency. Am J Physiol Heart Circ Physiol 2009; 296:H585-H593.
24. Reinisch W, Staun M, Tandon RK, et al. A randomized, openlabel, non-inferiority study of intravenous iron isomaltoside 1,000 (Monofer) compared with oral iron for treatment of anemia in IBD (Proceed). Am J Gastroenterol 2013;108:1877-1888.
25. Ganzoni AM. Intravenous iron-dextran: therapeutic and experimental possibilities. Schweiz Med Wochenschr 1970;100:301-303.