The calmodulin-binding transcription activator CAMTA1 is required for long-term memory formation in mice

Learning and Memory

Volumn 23, Issue 6, 2016, Pages 313-321

  Bas Orth, Carlos ^a   Tan, Yan Wei ^a   Oliveira, Ana M M ^a   Bengtson, C Peter ^a   Bading, Hilmar ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALMODULIN BINDING PROTEIN; CALMODULIN BINDING TRANSCRIPTION ACTIVATOR 1; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; CAMTA1 PROTEIN, MOUSE; CAMTA2 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTEXTUAL FEAR CONDITIONING TEST; CONTROLLED STUDY; DENDRITIC SPINE; DORSAL HIPPOCAMPUS; DOWN REGULATION; EXCITABILITY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENETIC TRANSCRIPTION; HIPPOCAMPAL SLICE; IMMUNOBLOTTING; LONG TERM MEMORY; MALE; MEMORY TEST; MOUSE; NONHUMAN; OBJECT PLACE RECOGNITION TEST; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SHORT TERM MEMORY; SYNAPTIC TRANSMISSION; UPREGULATION; WHOLE CELL PATCH CLAMP; ANIMAL; C57BL MOUSE; CELL CULTURE; CONDITIONED REFLEX; CYTOLOGY; DENDRITE; FEAR; GENE EXPRESSION REGULATION; GENE KNOCKDOWN; GENETICS; HIPPOCAMPUS; METABOLISM; PHYSIOLOGY; RECOGNITION;

ANIMALS; CALCIUM-BINDING PROTEINS; CALMODULIN-BINDING PROTEINS; CELLS, CULTURED; CONDITIONING, CLASSICAL; DENDRITES; FEAR; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HIPPOCAMPUS; MALE; MEMORY, LONG-TERM; MICE, INBRED C57BL; PYRAMIDAL CELLS; RECOGNITION (PSYCHOLOGY); SYNAPTIC TRANSMISSION; TRANS-ACTIVATORS;

EID: 84978435184     PISSN: 10720502     EISSN: 15495485     Source Type: Journal    
DOI: 10.1101/lm.041111.115     Document Type: Article

References (28)

1. Alberini CM. 2009. Transcription factors in long-term memory and synaptic plasticity. Physiol Rev 89: 121-145.
2. Anders S, Pyl PT, HuberW. 2015. HTSeq-a Python framework to work with high-throughput sequencing data. Bioinformatics 31: 166-169.
3. Bading H. 2013. Nuclear calcium signalling in the regulation of brain function. Nat Rev Neurosci 14: 593-608.
4. Bading H, Greenberg ME. 1991. Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 253: 912-914.
5. Bading H, Ginty DD, Greenberg ME. 1993. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260: 181-186.
6. Bouché N, Scharlat A, Snedden W, Bouchez D, Fromm H. 2002. A novel family of calmodulin-binding transcription activators in multicellular organisms. J Biol Chem 277: 21851-21861.
7. Finkler A, Ashery-Padan R, Fromm H. 2007. CAMTAs: Calmodulin-binding transcription activators from plants to human. FEBS Lett 581: 3893-3898.
8. Han J, Gong P, Reddig K, Mitra M, Guo P, Li HS. 2006. The fly CAMTA transcription factor potentiates deactivation of rhodopsin, a G protein-coupled light receptor. Cell 127: 847-858.
9. Henrich KO, Bauer T, Schulte J, Ehemann V, Deubzer H, Gogolin S, Muth D, Fischer M, Benner A, Konig R, et al. 2011. CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programs in neuroblastoma cells. Cancer Res 71: 3142-3151.
10. Huentelman MJ, Papassotiropoulos A, Craig DW, Hoerndli FJ, Pearson JV, Huynh KD, Corneveaux J, Hanggi J, Mondadori CR, Buchmann A, et al. 2007. Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Hum Mol Genet 16: 1469-1477.
11. Lau D, Bading H. 2009. Synaptic activity-mediated suppression of p53 and induction of nuclear calcium-regulated neuroprotective genes promote survival through inhibition of mitochondrial permeability transition. J Neurosci 29: 4420-4429.
12. Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS, Byrnes EJ, et al. 2007. Genome-wide atlas of gene expression in the adult mouse brain. Nature 445: 168-176.
13. Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R; 1000 Genome Project Data Processing Subgroup. 2009. The Sequence Alignment/Map format and SAMtools. Bioinformatics 25: 2078-2079.
14. Limback-Stokin K, Korzus E, Nagaoka-Yasuda R, Mayford M. 2004. Nuclear calcium/calmodulin regulates memory consolidation. J Neurosci 24: 10858-10867.
15. Long C, Grueter CE, Song K, Qin S, Qi X, Kong YM, Shelton JM, Richardson JA, Zhang CL, Bassel-Duby R, et al. 2014. Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor. Proc Natl Acad Sci 111: 11521-11526.
16. Mauceri D, Freitag HE, Oliveira AM, Bengtson CP, Bading H. 2011. Nuclear calcium-VEGFD signaling controls maintenance of dendrite arborization necessary for memory formation. Neuron 71: 117-130.
17. Mellstrom B, Savignac M, Gomez-Villafuertes R, Naranjo JR. 2008. Ca2+-operated transcriptional networks: Molecular mechanisms and in vivo models. Physiol Rev 88: 421-449.
18. Miller LA, Gunstad J, Spitznagel MB, McCaffery J, McGeary J, Poppas A, Paul RH, Sweet LH, Cohen RA. 2011. CAMTA1 T polymorphism is associated with neuropsychological test performance in older adults with cardiovascular disease. Psychogeriatrics 11: 135-140.
19. Oliveira AM, Hemstedt TJ, Bading H. 2012. Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities. Nat Neurosci 15: 1111-1113.
20. Song K, Backs J, McAnally J, Qi X, Gerard RD, Richardson JA, Hill JA, Bassel-Duby R, Olson EN. 2006. The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell 125: 453-466.
21. Stoppini L, Buchs PA, Muller D. 1991. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37: 173-182.
22. Thevenon J, Lopez E, Keren B, Heron D, Mignot C, Altuzarra C, Beri-Dexheimer M, Bonnet C, Magnin E, Burglen L, et al. 2012. Intragenic CAMTA1 rearrangements cause non-progressive congenital ataxia with or without intellectual disability. J Med Genet 49: 400-408.
23. Trapnell C, Pachter L, Salzberg SL. 2009. TopHat: Discovering splice junctions with RNA-Seq. Bioinformatics 25: 1105-1111.
24. Uhlen M, Oksvold P, Fagerberg L, Lundberg E, Jonasson K, Forsberg M, Zwahlen M, Kampf C, Wester K, Hober S, et al. 2010. Towards a knowledge-based Human Protein Atlas. Nat Biotechnol 28: 1248-1250.
25. West AE, Greenberg ME. 2011. Neuronal activity-regulated gene transcription in synapse development and cognitive function. Cold Spring Harb Perspect Biol 3. doi: 10.1101/cshperspect.a005744.
26. Yang T, Poovaiah BW. 2002. A calmodulin-binding/CGCG box DNA-binding protein family involved in multiple signaling pathways in plants. J Biol Chem 277: 45049-45058.
27. Zhang SJ, Steijaert MN, Lau D, Schutz G, Delucinge-Vivier C, Descombes P, Bading H. 2007. Decoding NMDA receptor signaling: Identification of genomic programs specifying neuronal survival and death. Neuron 53: 549-562.
28. Zhang SJ, Zou M, Lu L, Lau D, Ditzel DA, Delucinge-Vivier C, Aso Y, Descombes P, Bading H. 2009. Nuclear calcium signaling controls expression of a large gene pool: Identification of a gene program for acquired neuroprotection induced by synaptic activity. PLoS Genet 5: E1000604.