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Volumn 6, Issue , 2016, Pages

Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOKINE; ONIONIN A; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN; SULFOXIDE; THIOPHENE DERIVATIVE;

EID: 84978419850     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep29588     Document Type: Article
Times cited : (40)

References (28)
  • 2
    • 33645760428 scopus 로고    scopus 로고
    • Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
    • Hagemann, T. et al. Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J Immunol. 176, 5023-5032 (2006).
    • (2006) J Immunol , vol.176 , pp. 5023-5032
    • Hagemann, T.1
  • 3
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • Mantovani, A., Schioppa, T., Porta, C., Allavena, P. & Sica, A. Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metast Rev. 25, 315-322 (2006).
    • (2006) Cancer Metast Rev , vol.25 , pp. 315-322
    • Mantovani, A.1    Schioppa, T.2    Porta, C.3    Allavena, P.4    Sica, A.5
  • 4
    • 77950397414 scopus 로고    scopus 로고
    • Macrophage fusion cuisine
    • Sica, A. & Mantovani, A. Macrophage fusion cuisine. Blood. 114, 4609-4610 (2009).
    • (2009) Blood , vol.114 , pp. 4609-4610
    • Sica, A.1    Mantovani, A.2
  • 5
    • 31544441610 scopus 로고    scopus 로고
    • Distinct role of macrophages in different tumor microenvironments
    • Lewis, C. E. & Pollard, J. W. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 66, 605-612 (2006).
    • (2006) Cancer Res , vol.66 , pp. 605-612
    • Lewis, C.E.1    Pollard, J.W.2
  • 6
    • 77957028841 scopus 로고    scopus 로고
    • Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
    • Takaishi, K. et al. Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation. Cancer Sci. 101, 2128-2136 (2010).
    • (2010) Cancer Sci , vol.101 , pp. 2128-2136
    • Takaishi, K.1
  • 7
    • 65349163532 scopus 로고    scopus 로고
    • Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors
    • Kawamura, K., Komohara, Y., Takaishi, K., Katabuchi, H. & Takeya, M. Detection of M2 macrophages and colony-stimulating factor 1 expression in serous and mucinous ovarian epithelial tumors. Pathol Int. 59, 300-305 (2009).
    • (2009) Pathol Int , vol.59 , pp. 300-305
    • Kawamura, K.1    Komohara, Y.2    Takaishi, K.3    Katabuchi, H.4    Takeya, M.5
  • 8
    • 33845865825 scopus 로고    scopus 로고
    • Crosstalk between cancer and immune cells: Role of STAT3 in the tumour microenvironment
    • Yu, H., Kortylewski, M. & Pardoll, D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev. Immunol. 7, 41-51 (2007).
    • (2007) Nat Rev. Immunol , vol.7 , pp. 41-51
    • Yu, H.1    Kortylewski, M.2    Pardoll, D.3
  • 9
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu, H., Pardoll, D. & Jove, R. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer. 9, 798-809 (2009).
    • (2009) Nat Rev Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 10
    • 84892865013 scopus 로고    scopus 로고
    • Clinical significance of macrophage heterogeneity in human malignant tumors
    • Komohara, Y., Jinushi, M. & Takeya, M. Clinical significance of macrophage heterogeneity in human malignant tumors. Cancer Sci. 105, 1-8 (2014).
    • (2014) Cancer Sci , vol.105 , pp. 1-8
    • Komohara, Y.1    Jinushi, M.2    Takeya, M.3
  • 11
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • Pollard, J. W. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 4, 71-78 (2004).
    • (2004) Nat Rev Cancer , vol.4 , pp. 71-78
    • Pollard, J.W.1
  • 12
    • 63149088164 scopus 로고    scopus 로고
    • Trophic macrophages in development and disease
    • Pollard, J. W. Trophic macrophages in development and disease. Nat Rev Immunol. 9, 259-270 (2009).
    • (2009) Nat Rev Immunol , vol.9 , pp. 259-270
    • Pollard, J.W.1
  • 13
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce, J. A. & Pollard, J. W. Microenvironmental regulation of metastasis. Nat Rev Cancer. 9, 239-252 (2009).
    • (2009) Nat Rev Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 14
    • 84904406680 scopus 로고    scopus 로고
    • Tumor-associated macrophages: From mechanisms to therapy
    • Noy, R. & Pollard, J. W. Tumor-associated macrophages: from mechanisms to therapy. Immunity. 41, 49-61 (2014).
    • (2014) Immunity , vol.41 , pp. 49-61
    • Noy, R.1    Pollard, J.W.2
  • 15
    • 78650218768 scopus 로고    scopus 로고
    • Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages
    • Fujiwara, Y., Komohara, Y., Ikeda, T. & Takeya, M. Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. Cancer Sci. 102, 206-211 (2011).
    • (2011) Cancer Sci , vol.102 , pp. 206-211
    • Fujiwara, Y.1    Komohara, Y.2    Ikeda, T.3    Takeya, M.4
  • 16
    • 84878913009 scopus 로고    scopus 로고
    • Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells
    • Horlad, H. et al. Corosolic acid impairs tumor development and lung metastasis by inhibiting the immunosuppressive activity of myeloid-derived suppressor cells. Mol Nutr Food Res. 57, 1046-1054 (2013).
    • (2013) Mol Nutr Food Res , vol.57 , pp. 1046-1054
    • Horlad, H.1
  • 17
    • 84886779155 scopus 로고    scopus 로고
    • Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling
    • Fujiwara, Y. et al. Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling. Oncol Lett. 6, 1619-1623 (2013).
    • (2013) Oncol Lett , vol.6 , pp. 1619-1623
    • Fujiwara, Y.1
  • 18
    • 80053516019 scopus 로고    scopus 로고
    • Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3
    • Fujiwara, Y. et al. Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3. Oncol Rep. 26, 1533-1537 (2011).
    • (2011) Oncol Rep , vol.26 , pp. 1533-1537
    • Fujiwara, Y.1
  • 19
    • 84897533875 scopus 로고    scopus 로고
    • A novel strategy for inducing the antitumor effects of triterpenoid compounds: Blocking the protumoral functions of tumor-associated macrophages via STAT3 inhibition
    • Fujiwara, Y., Takeya, M. & Komohara, Y. A novel strategy for inducing the antitumor effects of triterpenoid compounds: blocking the protumoral functions of tumor-associated macrophages via STAT3 inhibition. BioMed Res Int. 2014, 348539 (2014).
    • (2014) BioMed Res Int , vol.2014
    • Fujiwara, Y.1    Takeya, M.2    Komohara, Y.3
  • 20
    • 77954893597 scopus 로고    scopus 로고
    • Onionin A from Allium cepa inhibits macrophage activation
    • El-Aasr, M. et al. Onionin A from Allium cepa inhibits macrophage activation. J Nat Prod. 73, 1306-1308 (2010).
    • (2010) J Nat Prod , vol.73 , pp. 1306-1308
    • El-Aasr, M.1
  • 21
    • 84921827228 scopus 로고    scopus 로고
    • Ting-Chao Frequently asked questions in drug combinations and the mass-action law-based answers
    • Chou, Ting-Chao Frequently asked questions in drug combinations and the mass-action law-based answers. Synergy 1, 3-21 (2014).
    • (2014) Synergy , vol.1 , pp. 3-21
    • Chou1
  • 22
    • 42149099408 scopus 로고    scopus 로고
    • Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
    • Biswas, S. K., Sica, A. & Lewis, C. E. Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol. 180, 2011-2017 (2008).
    • (2008) J Immunol , vol.180 , pp. 2011-2017
    • Biswas, S.K.1    Sica, A.2    Lewis, C.E.3
  • 23
    • 33751575658 scopus 로고    scopus 로고
    • The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis
    • Rosen, D. G. et al. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer 107, 2730-2740 (2006).
    • (2006) Cancer , vol.107 , pp. 2730-2740
    • Rosen, D.G.1
  • 24
    • 84917732490 scopus 로고    scopus 로고
    • Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer
    • Wen, W. et al. Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer. Mol Cancer Ther. 13, 3037-3048 (2014).
    • (2014) Mol Cancer Ther , vol.13 , pp. 3037-3048
    • Wen, W.1
  • 25
    • 84901014050 scopus 로고    scopus 로고
    • Targeted disruption of the JAK2/STAT3 pathway in combination with systemic administration of paclitaxel inhibits the priming of ovarian cancer stem cells leading to a reduced tumor burden
    • Abubaker, K. et al. Targeted disruption of the JAK2/STAT3 pathway in combination with systemic administration of paclitaxel inhibits the priming of ovarian cancer stem cells leading to a reduced tumor burden. Front Oncol. 4, 75 (2014).
    • (2014) Front Oncol , vol.4 , pp. 75
    • Abubaker, K.1
  • 26
    • 84867320871 scopus 로고    scopus 로고
    • Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: Molecular phenotype of chemoresistant ovarian tumors
    • Latifi, A. et al. Isolation and characterization of tumor cells from the ascites of ovarian cancer patients: molecular phenotype of chemoresistant ovarian tumors. PLoS One. 7, e46858 (2012).
    • (2012) PLoS One , vol.7
    • Latifi, A.1
  • 27
    • 80755187837 scopus 로고    scopus 로고
    • Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells
    • Motohara, T. et al. Transient depletion of p53 followed by transduction of c-Myc and K-Ras converts ovarian stem-like cells into tumor-initiating cells. Carcinogenesis. 32, 1597-1606 (2011).
    • (2011) Carcinogenesis , vol.32 , pp. 1597-1606
    • Motohara, T.1
  • 28
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • Komohara, Y., Ohnishi, K., Kuratsu, J. & Takeya, M. Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol. 216, 15-24 (2008).
    • (2008) J Pathol , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3    Takeya, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.