-
1
-
-
84959422707
-
-
Smart micro/nanoparticles in stimulus responsive drug/gene delivery systems., Chem Soc Rev, PMID 26776487.
-
Karimi M, Ghasemi A, Sahandi Zangabad P, Rahighi R, Moosavi Basri SM, Mirshekari H, Amiri M, Pishabad S, Aslani A, Bozorgomid M, et al. Smart micro/nanoparticles in stimulus responsive drug/gene delivery systems. Chem Soc Rev 2016. PMID 26776487.
-
(2016)
-
-
Karimi, M.1
Ghasemi, A.2
Sahandi Zangabad, P.3
Rahighi, R.4
Moosavi Basri, S.M.5
Mirshekari, H.6
Amiri, M.7
Pishabad, S.8
Aslani, A.9
Bozorgomid, M.10
-
2
-
-
84951759562
-
-
Dendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications., Int J Nanomed, PMID 26730187.
-
Kalomiraki M, Thermos K, Chaniotakis NA. Dendrimers as tunable vectors of drug delivery systems and biomedical and ocular applications. Int J Nanomed 2015. PMID 26730187.
-
(2015)
-
-
Kalomiraki, M.1
Thermos, K.2
Chaniotakis, N.A.3
-
3
-
-
84942784694
-
Clinical translation of nanomedicine
-
Min Y, Caster JM, Eblan MJ, Wang AZ. Clinical translation of nanomedicine. Chem Rev 2015, 115:11147–11190.
-
(2015)
Chem Rev
, vol.115
, pp. 11147-11190
-
-
Min, Y.1
Caster, J.M.2
Eblan, M.J.3
Wang, A.Z.4
-
4
-
-
0034880214
-
Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation
-
Gelderblom H, Verweij J, Nooter K, Sparreboom A. Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation. Eur J Cancer 2001, 37:1590–1598.
-
(2001)
Eur J Cancer
, vol.37
, pp. 1590-1598
-
-
Gelderblom, H.1
Verweij, J.2
Nooter, K.3
Sparreboom, A.4
-
5
-
-
0018885763
-
Suspected anaphylactic reaction to Cremophor EL
-
Dye D, Watkins J. Suspected anaphylactic reaction to Cremophor EL. Br Med J 1980, 280:1353.
-
(1980)
Br Med J
, vol.280
, pp. 1353
-
-
Dye, D.1
Watkins, J.2
-
6
-
-
0032516078
-
Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment
-
Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, Jain RK. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA 1998, 95:4607–4612.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4607-4612
-
-
Hobbs, S.K.1
Monsky, W.L.2
Yuan, F.3
Roberts, W.G.4
Griffith, L.5
Torchilin, V.P.6
Jain, R.K.7
-
7
-
-
32944482677
-
Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
-
Gradishar WJ, Tjulandin S, Davidson N, Shaw H, Desai N, Bhar P, Hawkins M, O'Shaughnessy J. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J Clin Oncol 2005, 23:7794–7803.
-
(2005)
J Clin Oncol
, vol.23
, pp. 7794-7803
-
-
Gradishar, W.J.1
Tjulandin, S.2
Davidson, N.3
Shaw, H.4
Desai, N.5
Bhar, P.6
Hawkins, M.7
O'Shaughnessy, J.8
-
8
-
-
84886741654
-
Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine
-
Von Hoff DD, Ervin T, Arena FP, Chiorean EG, Infante J, Moore M, Seay T, Tjulandin SA, Ma WW, Saleh MN, et al. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med 2013, 369:1691–1703.
-
(2013)
N Engl J Med
, vol.369
, pp. 1691-1703
-
-
Von Hoff, D.D.1
Ervin, T.2
Arena, F.P.3
Chiorean, E.G.4
Infante, J.5
Moore, M.6
Seay, T.7
Tjulandin, S.A.8
Ma, W.W.9
Saleh, M.N.10
-
9
-
-
84873252557
-
Liposomal drug delivery systems: from concept to clinical applications
-
Allen TM, Cullis PR. Liposomal drug delivery systems: from concept to clinical applications. Adv Drug Deliv Rev 2013, 65:36–48.
-
(2013)
Adv Drug Deliv Rev
, vol.65
, pp. 36-48
-
-
Allen, T.M.1
Cullis, P.R.2
-
10
-
-
84879400160
-
A phase I study of CPX-351 in combination with busulfan and fludarabine conditioning and allogeneic stem cell transplantation in adult patients with refractory acute leukemia
-
Gergis U, Roboz G, Shore T, Ritchie E, Mayer S, Wissa U, McKenna M, Christos P, Pearse R, Mark T, et al. A phase I study of CPX-351 in combination with busulfan and fludarabine conditioning and allogeneic stem cell transplantation in adult patients with refractory acute leukemia. Biol Blood Marrow Transplant 2013, 19:1040–1045.
-
(2013)
Biol Blood Marrow Transplant
, vol.19
, pp. 1040-1045
-
-
Gergis, U.1
Roboz, G.2
Shore, T.3
Ritchie, E.4
Mayer, S.5
Wissa, U.6
McKenna, M.7
Christos, P.8
Pearse, R.9
Mark, T.10
-
11
-
-
84901412022
-
Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML
-
Lancet JE, Cortes JE, Hogge DE, Tallman MS, Kovacsovics TJ, Damon LE, Komrokji R, Solomon SR, Kolitz JE, Cooper M, et al. Phase 2 trial of CPX-351, a fixed 5:1 molar ratio of cytarabine/daunorubicin, vs cytarabine/daunorubicin in older adults with untreated AML. Blood 2014, 123:3239–3246.
-
(2014)
Blood
, vol.123
, pp. 3239-3246
-
-
Lancet, J.E.1
Cortes, J.E.2
Hogge, D.E.3
Tallman, M.S.4
Kovacsovics, T.J.5
Damon, L.E.6
Komrokji, R.7
Solomon, S.R.8
Kolitz, J.E.9
Cooper, M.10
-
12
-
-
84920870589
-
Phase II, multicenter, randomized trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus intensive salvage therapy in adults with first relapse AML
-
Cortes JE, Goldberg SL, Feldman EJ, Rizzeri DA, Hogge DE, Larson M, Pigneux A, Recher C, Schiller G, Warzocha K, et al. Phase II, multicenter, randomized trial of CPX-351 (cytarabine:daunorubicin) liposome injection versus intensive salvage therapy in adults with first relapse AML. Cancer 2015, 121:234–242.
-
(2015)
Cancer
, vol.121
, pp. 234-242
-
-
Cortes, J.E.1
Goldberg, S.L.2
Feldman, E.J.3
Rizzeri, D.A.4
Hogge, D.E.5
Larson, M.6
Pigneux, A.7
Recher, C.8
Schiller, G.9
Warzocha, K.10
-
13
-
-
84871191244
-
Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors
-
Infante JR, Keedy VL, Jones SF, Zamboni WC, Chan E, Bendell JC, Lee W, Wu H, Ikeda S, Kodaira H, et al. Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors. Cancer Chemother Pharmacol 2012, 70:699–705.
-
(2012)
Cancer Chemother Pharmacol
, vol.70
, pp. 699-705
-
-
Infante, J.R.1
Keedy, V.L.2
Jones, S.F.3
Zamboni, W.C.4
Chan, E.5
Bendell, J.C.6
Lee, W.7
Wu, H.8
Ikeda, S.9
Kodaira, H.10
-
14
-
-
84883169930
-
A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer
-
Ko AH, Tempero MA, Shan YS, Su WC, Lin YL, Dito E, Ong A, Wang YW, Yeh CG, Chen LT. A multinational phase 2 study of nanoliposomal irinotecan sucrosofate (PEP02, MM-398) for patients with gemcitabine-refractory metastatic pancreatic cancer. Br J Cancer 2013, 109:920–925.
-
(2013)
Br J Cancer
, vol.109
, pp. 920-925
-
-
Ko, A.H.1
Tempero, M.A.2
Shan, Y.S.3
Su, W.C.4
Lin, Y.L.5
Dito, E.6
Ong, A.7
Wang, Y.W.8
Yeh, C.G.9
Chen, L.T.10
-
15
-
-
84861658483
-
Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: studies with human gastro-entero-pancreatic ectopic tumor models
-
Gabizon A, Amitay Y, Tzemach D, Gorin J, Shmeeda H, Zalipsky S. Therapeutic efficacy of a lipid-based prodrug of mitomycin C in pegylated liposomes: studies with human gastro-entero-pancreatic ectopic tumor models. J Control Release 2012, 160:245–253.
-
(2012)
J Control Release
, vol.160
, pp. 245-253
-
-
Gabizon, A.1
Amitay, Y.2
Tzemach, D.3
Gorin, J.4
Shmeeda, H.5
Zalipsky, S.6
-
16
-
-
33645652328
-
Reduced toxicity and superior therapeutic activity of a mitomycin C lipid-based prodrug incorporated in pegylated liposomes
-
Gabizon AA, Tzemach D, Horowitz AT, Shmeeda H, Yeh J, Zalipsky S. Reduced toxicity and superior therapeutic activity of a mitomycin C lipid-based prodrug incorporated in pegylated liposomes. Clin Cancer Res 2006, 12:1913–1920.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1913-1920
-
-
Gabizon, A.A.1
Tzemach, D.2
Horowitz, A.T.3
Shmeeda, H.4
Yeh, J.5
Zalipsky, S.6
-
17
-
-
77955194093
-
Liposomal cisplatin: a new cisplatin formulation
-
Stathopoulos GP. Liposomal cisplatin: a new cisplatin formulation. Anticancer Drugs 2010, 21:732–736.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 732-736
-
-
Stathopoulos, G.P.1
-
18
-
-
77950546060
-
Phase II study of liposomal cisplatin (SPI-77) in platinum-sensitive recurrences of ovarian cancer
-
Seetharamu N, Kim E, Hochster H, Martin F, Muggia F. Phase II study of liposomal cisplatin (SPI-77) in platinum-sensitive recurrences of ovarian cancer. Anticancer Res 2010, 30:541–545.
-
(2010)
Anticancer Res
, vol.30
, pp. 541-545
-
-
Seetharamu, N.1
Kim, E.2
Hochster, H.3
Martin, F.4
Muggia, F.5
-
19
-
-
53249131199
-
Pharmacokinetic/pharmacodynamic modeling and simulation of neutropenia during phase I development of liposome-entrapped paclitaxel
-
Fetterly GJ, Grasela TH, Sherman JW, Dul JL, Grahn A, Lecomte D, Fiedler-Kelly J, Damjanov N, Fishman M, Kane MP, et al. Pharmacokinetic/pharmacodynamic modeling and simulation of neutropenia during phase I development of liposome-entrapped paclitaxel. Clin Cancer Res 2008, 14:5856–5863.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5856-5863
-
-
Fetterly, G.J.1
Grasela, T.H.2
Sherman, J.W.3
Dul, J.L.4
Grahn, A.5
Lecomte, D.6
Fiedler-Kelly, J.7
Damjanov, N.8
Fishman, M.9
Kane, M.P.10
-
20
-
-
33244477825
-
Efficacy and safety of paclitaxel poliglumex as first-line chemotherapy in patients at high risk with advanced-stage non-small-cell lung cancer: results of a phase II study
-
Richards DA, Richards P, Bodkin D, Neubauer MA, Oldham F. Efficacy and safety of paclitaxel poliglumex as first-line chemotherapy in patients at high risk with advanced-stage non-small-cell lung cancer: results of a phase II study. Clin Lung Cancer 2005, 7:215–220.
-
(2005)
Clin Lung Cancer
, vol.7
, pp. 215-220
-
-
Richards, D.A.1
Richards, P.2
Bodkin, D.3
Neubauer, M.A.4
Oldham, F.5
-
21
-
-
43649092756
-
Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer
-
Paz-Ares L, Ross H, O'Brien M, Riviere A, Gatzemeier U, Von Pawel J, Kaukel E, Freitag L, Digel W, Bischoff H, et al. Phase III trial comparing paclitaxel poliglumex vs docetaxel in the second-line treatment of non-small-cell lung cancer. Br J Cancer 2008, 98:1608–1613.
-
(2008)
Br J Cancer
, vol.98
, pp. 1608-1613
-
-
Paz-Ares, L.1
Ross, H.2
O'Brien, M.3
Riviere, A.4
Gatzemeier, U.5
Von Pawel, J.6
Kaukel, E.7
Freitag, L.8
Digel, W.9
Bischoff, H.10
-
22
-
-
50349101826
-
Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer
-
O'Brien ME, Socinski MA, Popovich AY, Bondarenko IN, Tomova A, Bilynsky BT, Hotko YS, Ganul VL, Kostinsky IY, Eisenfeld AJ, et al. Randomized phase III trial comparing single-agent paclitaxel Poliglumex (CT-2103, PPX) with single-agent gemcitabine or vinorelbine for the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer. J Thorac Oncol 2008, 3:728–734.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 728-734
-
-
O'Brien, M.E.1
Socinski, M.A.2
Popovich, A.Y.3
Bondarenko, I.N.4
Tomova, A.5
Bilynsky, B.T.6
Hotko, Y.S.7
Ganul, V.L.8
Kostinsky, I.Y.9
Eisenfeld, A.J.10
-
23
-
-
44649193032
-
Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer
-
Langer CJ, O'Byrne KJ, Socinski MA, Mikhailov SM, Lesniewski-Kmak K, Smakal M, Ciuleanu TE, Orlov SV, Dediu M, Heigener D, et al. Phase III trial comparing paclitaxel poliglumex (CT-2103, PPX) in combination with carboplatin versus standard paclitaxel and carboplatin in the treatment of PS 2 patients with chemotherapy-naive advanced non-small cell lung cancer. J Thorac Oncol 2008, 3:623–630.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 623-630
-
-
Langer, C.J.1
O'Byrne, K.J.2
Socinski, M.A.3
Mikhailov, S.M.4
Lesniewski-Kmak, K.5
Smakal, M.6
Ciuleanu, T.E.7
Orlov, S.V.8
Dediu, M.9
Heigener, D.10
-
24
-
-
61449184602
-
A phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors
-
Verschraegen CF, Skubitz K, Daud A, Kudelka AP, Rabinowitz I, Allievi C, Eisenfeld A, Singer JW, Oldham FB. A phase I and pharmacokinetic study of paclitaxel poliglumex and cisplatin in patients with advanced solid tumors. Cancer Chemother Pharmacol 2009, 63:903–910.
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 903-910
-
-
Verschraegen, C.F.1
Skubitz, K.2
Daud, A.3
Kudelka, A.P.4
Rabinowitz, I.5
Allievi, C.6
Eisenfeld, A.7
Singer, J.W.8
Oldham, F.B.9
-
25
-
-
50149116962
-
Paclitaxel poliglumex and carboplatin as first-line therapy in ovarian, peritoneal or fallopian tube cancer: a phase I and feasibility trial of the Gynecologic Oncology Group
-
Morgan MA, Darcy KM, Rose PG, DeGeest K, Bookman MA, Aikins JK, Sill MW, Mannel RS, Allievi C, Egorin MJ, et al. Paclitaxel poliglumex and carboplatin as first-line therapy in ovarian, peritoneal or fallopian tube cancer: a phase I and feasibility trial of the Gynecologic Oncology Group. Gynecol Oncol 2008, 110:329–335.
-
(2008)
Gynecol Oncol
, vol.110
, pp. 329-335
-
-
Morgan, M.A.1
Darcy, K.M.2
Rose, P.G.3
DeGeest, K.4
Bookman, M.A.5
Aikins, J.K.6
Sill, M.W.7
Mannel, R.S.8
Allievi, C.9
Egorin, M.J.10
-
26
-
-
56749178680
-
A phase II trial of paclitaxel poliglumex in recurrent or persistent ovarian or primary peritoneal cancer (EOC): a Gynecologic Oncology Group Study
-
Sabbatini P, Sill MW, O'Malley D, Adler L, Secord AA, Gynecologic Oncology Group Study. A phase II trial of paclitaxel poliglumex in recurrent or persistent ovarian or primary peritoneal cancer (EOC): a Gynecologic Oncology Group Study. Gynecol Oncol 2008, 111:455–460.
-
(2008)
Gynecol Oncol
, vol.111
, pp. 455-460
-
-
Sabbatini, P.1
Sill, M.W.2
O'Malley, D.3
Adler, L.4
Secord, A.A.5
-
27
-
-
33746799835
-
Paclitaxel poliglumex (PPX-Xyotax) and concurrent radiation for esophageal and gastric cancer: a phase I study
-
Dipetrillo T, Milas L, Evans D, Akerman P, Ng T, Miner T, Cruff D, Chauhan B, Iannitti D, Harrington D, et al. Paclitaxel poliglumex (PPX-Xyotax) and concurrent radiation for esophageal and gastric cancer: a phase I study. Am J Clin Oncol 2006, 29:376–379.
-
(2006)
Am J Clin Oncol
, vol.29
, pp. 376-379
-
-
Dipetrillo, T.1
Milas, L.2
Evans, D.3
Akerman, P.4
Ng, T.5
Miner, T.6
Cruff, D.7
Chauhan, B.8
Iannitti, D.9
Harrington, D.10
-
28
-
-
84856236634
-
Neoadjuvant paclitaxel poliglumex, cisplatin, and radiation for esophageal cancer: a phase 2 trial
-
Dipetrillo T, Suntharalingam M, Ng T, Fontaine J, Horiba N, Oldenburg N, Perez K, Birnbaum A, Battafarano R, Burrows W, et al. Neoadjuvant paclitaxel poliglumex, cisplatin, and radiation for esophageal cancer: a phase 2 trial. Am J Clin Oncol 2012, 35:64–67.
-
(2012)
Am J Clin Oncol
, vol.35
, pp. 64-67
-
-
Dipetrillo, T.1
Suntharalingam, M.2
Ng, T.3
Fontaine, J.4
Horiba, N.5
Oldenburg, N.6
Perez, K.7
Birnbaum, A.8
Battafarano, R.9
Burrows, W.10
-
29
-
-
84914681252
-
Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study
-
Jeyapalan S, Boxerman J, Donahue J, Goldman M, Kinsella T, Dipetrillo T, Evans D, Elinzano H, Constantinou M, Stopa E, et al. Paclitaxel poliglumex, temozolomide, and radiation for newly diagnosed high-grade glioma: a Brown University Oncology Group Study. Am J Clin Oncol 2014, 37:444–449.
-
(2014)
Am J Clin Oncol
, vol.37
, pp. 444-449
-
-
Jeyapalan, S.1
Boxerman, J.2
Donahue, J.3
Goldman, M.4
Kinsella, T.5
Dipetrillo, T.6
Evans, D.7
Elinzano, H.8
Constantinou, M.9
Stopa, E.10
-
30
-
-
67650359893
-
Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models
-
Numbenjapon T, Wang J, Colcher D, Schluep T, Davis ME, Duringer J, Kretzner L, Yen Y, Forman SJ, Raubitschek A. Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models. Clin Cancer Res 2009, 15:4365–4373.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4365-4373
-
-
Numbenjapon, T.1
Wang, J.2
Colcher, D.3
Schluep, T.4
Davis, M.E.5
Duringer, J.6
Kretzner, L.7
Yen, Y.8
Forman, S.J.9
Raubitschek, A.10
-
31
-
-
84862689147
-
Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer
-
Gaur S, Chen L, Yen T, Wang Y, Zhou B, Davis M, Yen Y. Preclinical study of the cyclodextrin-polymer conjugate of camptothecin CRLX101 for the treatment of gastric cancer. Nanomedicine 2012, 8:721–730.
-
(2012)
Nanomedicine
, vol.8
, pp. 721-730
-
-
Gaur, S.1
Chen, L.2
Yen, T.3
Wang, Y.4
Zhou, B.5
Davis, M.6
Yen, Y.7
-
32
-
-
84880917692
-
First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies
-
Weiss GJ, Chao J, Neidhart JD, Ramanathan RK, Bassett D, Neidhart JA, Choi CH, Chow W, Chung V, Forman SJ, et al. First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies. Invest New Drugs 2013, 31:986–1000.
-
(2013)
Invest New Drugs
, vol.31
, pp. 986-1000
-
-
Weiss, G.J.1
Chao, J.2
Neidhart, J.D.3
Ramanathan, R.K.4
Bassett, D.5
Neidhart, J.A.6
Choi, C.H.7
Chow, W.8
Chung, V.9
Forman, S.J.10
-
33
-
-
2542559832
-
Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
-
Kim TY, Kim DW, Chung JY, Shin SG, Kim SC, Heo DS, Kim NK, Bang YJ. Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin Cancer Res 2004, 10:3708–3716.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3708-3716
-
-
Kim, T.Y.1
Kim, D.W.2
Chung, J.Y.3
Shin, S.G.4
Kim, S.C.5
Heo, D.S.6
Kim, N.K.7
Bang, Y.J.8
-
34
-
-
39749178252
-
Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer
-
Lee KS, Chung HC, Im SA, Park YH, Kim CS, Kim SB, Rha SY, Lee MY, Ro J. Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer. Breast Cancer Res Treat 2008, 108:241–250.
-
(2008)
Breast Cancer Res Treat
, vol.108
, pp. 241-250
-
-
Lee, K.S.1
Chung, H.C.2
Im, S.A.3
Park, Y.H.4
Kim, C.S.5
Kim, S.B.6
Rha, S.Y.7
Lee, M.Y.8
Ro, J.9
-
35
-
-
37349080672
-
Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer
-
Kim DW, Kim SY, Kim HK, Kim SW, Shin SW, Kim JS, Park K, Lee MY, Heo DS. Multicenter phase II trial of Genexol-PM, a novel Cremophor-free, polymeric micelle formulation of paclitaxel, with cisplatin in patients with advanced non-small-cell lung cancer. Ann Oncol 2007, 18:2009–2014.
-
(2007)
Ann Oncol
, vol.18
, pp. 2009-2014
-
-
Kim, D.W.1
Kim, S.Y.2
Kim, H.K.3
Kim, S.W.4
Shin, S.W.5
Kim, J.S.6
Park, K.7
Lee, M.Y.8
Heo, D.S.9
-
36
-
-
84907599028
-
A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer
-
Ahn HK, Jung M, Sym SJ, Shin DB, Kang SM, Kyung SY, Park JW, Jeong SH, Cho EK. A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer. Cancer Chemother Pharmacol 2014, 74:277–282.
-
(2014)
Cancer Chemother Pharmacol
, vol.74
, pp. 277-282
-
-
Ahn, H.K.1
Jung, M.2
Sym, S.J.3
Shin, D.B.4
Kang, S.M.5
Kyung, S.Y.6
Park, J.W.7
Jeong, S.H.8
Cho, E.K.9
-
37
-
-
77958073029
-
Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors
-
Hamaguchi T, Doi T, Eguchi-Nakajima T, Kato K, Yamada Y, Shimada Y, Fuse N, Ohtsu A, Matsumoto S, Takanashi M, et al. Phase I study of NK012, a novel SN-38-incorporating micellar nanoparticle, in adult patients with solid tumors. Clin Cancer Res 2010, 16:5058–5066.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5058-5066
-
-
Hamaguchi, T.1
Doi, T.2
Eguchi-Nakajima, T.3
Kato, K.4
Yamada, Y.5
Shimada, Y.6
Fuse, N.7
Ohtsu, A.8
Matsumoto, S.9
Takanashi, M.10
-
38
-
-
34447331464
-
A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation
-
Hamaguchi T, Kato K, Yasui H, Morizane C, Ikeda M, Ueno H, Muro K, Yamada Y, Okusaka T, Shirao K, et al. A phase I and pharmacokinetic study of NK105, a paclitaxel-incorporating micellar nanoparticle formulation. Br J Cancer 2007, 97:170–176.
-
(2007)
Br J Cancer
, vol.97
, pp. 170-176
-
-
Hamaguchi, T.1
Kato, K.2
Yasui, H.3
Morizane, C.4
Ikeda, M.5
Ueno, H.6
Muro, K.7
Yamada, Y.8
Okusaka, T.9
Shirao, K.10
-
39
-
-
20944450473
-
NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel
-
Hamaguchi T, Matsumura Y, Suzuki M, Shimizu K, Goda R, Nakamura I, Nakatomi I, Yokoyama M, Kataoka K, Kakizoe T. NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br J Cancer 2005, 92:1240–1246.
-
(2005)
Br J Cancer
, vol.92
, pp. 1240-1246
-
-
Hamaguchi, T.1
Matsumura, Y.2
Suzuki, M.3
Shimizu, K.4
Goda, R.5
Nakamura, I.6
Nakatomi, I.7
Yokoyama, M.8
Kataoka, K.9
Kakizoe, T.10
-
40
-
-
33748289523
-
NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel
-
Negishi T, Koizumi F, Uchino H, Kuroda J, Kawaguchi T, Naito S, Matsumura Y. NK105, a paclitaxel-incorporating micellar nanoparticle, is a more potent radiosensitising agent compared to free paclitaxel. Br J Cancer 2006, 95:601–606.
-
(2006)
Br J Cancer
, vol.95
, pp. 601-606
-
-
Negishi, T.1
Koizumi, F.2
Uchino, H.3
Kuroda, J.4
Kawaguchi, T.5
Naito, S.6
Matsumura, Y.7
-
41
-
-
0036807955
-
Pharmaceutical and biomedical differences between micellar doxorubicin (NK911) and liposomal doxorubicin (Doxil)
-
Tsukioka Y, Matsumura Y, Hamaguchi T, Koike H, Moriyasu F, Kakizoe T. Pharmaceutical and biomedical differences between micellar doxorubicin (NK911) and liposomal doxorubicin (Doxil). Jpn J Cancer Res 2002, 93:1145–1153.
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 1145-1153
-
-
Tsukioka, Y.1
Matsumura, Y.2
Hamaguchi, T.3
Koike, H.4
Moriyasu, F.5
Kakizoe, T.6
-
42
-
-
10844293438
-
Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin
-
Matsumura Y, Hamaguchi T, Ura T, Muro K, Yamada Y, Shimada Y, Shirao K, Okusaka T, Ueno H, Ikeda M, et al. Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin. Br J Cancer 2004, 91:1775–1781.
-
(2004)
Br J Cancer
, vol.91
, pp. 1775-1781
-
-
Matsumura, Y.1
Hamaguchi, T.2
Ura, T.3
Muro, K.4
Yamada, Y.5
Shimada, Y.6
Shirao, K.7
Okusaka, T.8
Ueno, H.9
Ikeda, M.10
-
43
-
-
84855921796
-
A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction
-
Valle JW, Armstrong A, Newman C, Alakhov V, Pietrzynski G, Brewer J, Campbell S, Corrie P, Rowinsky EK, Ranson M. A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction. Invest New Drugs 2011, 29:1029–1037.
-
(2011)
Invest New Drugs
, vol.29
, pp. 1029-1037
-
-
Valle, J.W.1
Armstrong, A.2
Newman, C.3
Alakhov, V.4
Pietrzynski, G.5
Brewer, J.6
Campbell, S.7
Corrie, P.8
Rowinsky, E.K.9
Ranson, M.10
-
44
-
-
79951682119
-
A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours
-
Plummer R, Wilson RH, Calvert H, Boddy AV, Griffin M, Sludden J, Tilby MJ, Eatock M, Pearson DG, Ottley CJ, et al. A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours. Br J Cancer 2011, 104:593–598.
-
(2011)
Br J Cancer
, vol.104
, pp. 593-598
-
-
Plummer, R.1
Wilson, R.H.2
Calvert, H.3
Boddy, A.V.4
Griffin, M.5
Sludden, J.6
Tilby, M.J.7
Eatock, M.8
Pearson, D.G.9
Ottley, C.J.10
-
45
-
-
84902983923
-
Assessment of antitumor activity and acute peripheral neuropathy of 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016)
-
Ueno T, Endo K, Hori K, Ozaki N, Tsuji A, Kondo S, Wakisaka N, Murono S, Kataoka K, Kato Y, et al. Assessment of antitumor activity and acute peripheral neuropathy of 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016). Int J Nanomedicine 2014, 9:3005–3012.
-
(2014)
Int J Nanomedicine
, vol.9
, pp. 3005-3012
-
-
Ueno, T.1
Endo, K.2
Hori, K.3
Ozaki, N.4
Tsuji, A.5
Kondo, S.6
Wakisaka, N.7
Murono, S.8
Kataoka, K.9
Kato, Y.10
-
46
-
-
84899460500
-
Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model
-
Yamamoto Y, Hyodo I, Takigahira M, Koga Y, Yasunaga M, Harada M, Hayashi T, Kato Y, Matsumura Y. Effect of combined treatment with the epirubicin-incorporating micelles (NC-6300) and 1,2-diaminocyclohexane platinum (II)-incorporating micelles (NC-4016) on a human gastric cancer model. Int J Cancer 2014, 135:214–223.
-
(2014)
Int J Cancer
, vol.135
, pp. 214-223
-
-
Yamamoto, Y.1
Hyodo, I.2
Takigahira, M.3
Koga, Y.4
Yasunaga, M.5
Harada, M.6
Hayashi, T.7
Kato, Y.8
Matsumura, Y.9
-
47
-
-
84858665432
-
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile
-
Hrkach J, Von Hoff D, Mukkaram Ali M, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, et al. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci Transl Med 2012, 4:128ra139.
-
(2012)
Sci Transl Med
, vol.4
, pp. 128ra139
-
-
Hrkach, J.1
Von Hoff, D.2
Mukkaram Ali, M.3
Andrianova, E.4
Auer, J.5
Campbell, T.6
De Witt, D.7
Figa, M.8
Figueiredo, M.9
Horhota, A.10
-
48
-
-
84911441206
-
PSMA ligand conjugated PCL-PEG polymeric micelles targeted to prostate cancer cells
-
Jin J, Sui B, Gou J, Liu J, Tang X, Xu H, Zhang Y, Jin X. PSMA ligand conjugated PCL-PEG polymeric micelles targeted to prostate cancer cells. PLoS One 2014, 9:e112200.
-
(2014)
PLoS One
, vol.9
-
-
Jin, J.1
Sui, B.2
Gou, J.3
Liu, J.4
Tang, X.5
Xu, H.6
Zhang, Y.7
Jin, X.8
-
49
-
-
84929376457
-
Expression of prostate-specific membrane antigen in lung cancer cells and tumor neovasculature endothelial cells and its clinical significance
-
Wang HL, Wang SS, Song WH, Pan Y, Yu HP, Si TG, Liu Y, Cui XN, Guo Z. Expression of prostate-specific membrane antigen in lung cancer cells and tumor neovasculature endothelial cells and its clinical significance. PLoS One 2015, 10:e0125924.
-
(2015)
PLoS One
, vol.10
-
-
Wang, H.L.1
Wang, S.S.2
Song, W.H.3
Pan, Y.4
Yu, H.P.5
Si, T.G.6
Liu, Y.7
Cui, X.N.8
Guo, Z.9
-
50
-
-
84911990896
-
Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications
-
Kannan RM, Nance E, Kannan S, Tomalia DA. Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications. J Intern Med 2014, 276:579–617.
-
(2014)
J Intern Med
, vol.276
, pp. 579-617
-
-
Kannan, R.M.1
Nance, E.2
Kannan, S.3
Tomalia, D.A.4
-
51
-
-
84885386826
-
Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: a concise overview
-
Mignani S, El Kazzouli S, Bousmina M, Majoral JP. Expand classical drug administration ways by emerging routes using dendrimer drug delivery systems: a concise overview. Adv Drug Deliv Rev 2013, 65:1316–1330.
-
(2013)
Adv Drug Deliv Rev
, vol.65
, pp. 1316-1330
-
-
Mignani, S.1
El Kazzouli, S.2
Bousmina, M.3
Majoral, J.P.4
-
52
-
-
47249140441
-
Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications
-
Laurent S, Forge D, Port M, Roch A, Robic C, Vander Elst L, Muller RN. Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 2008, 108:2064–2110.
-
(2008)
Chem Rev
, vol.108
, pp. 2064-2110
-
-
Laurent, S.1
Forge, D.2
Port, M.3
Roch, A.4
Robic, C.5
Vander Elst, L.6
Muller, R.N.7
-
53
-
-
0031055571
-
Heat response of HT29 cells depends strongly on perfusion - a 31P NMR spectroscopy, HPLC and cell survival analysis
-
Hentschel M, Mirtsch S, Jordan A, Wust P, Vogl T, Semmler W, Wolf KJ, Felix R. Heat response of HT29 cells depends strongly on perfusion - a 31P NMR spectroscopy, HPLC and cell survival analysis. Int J Hyperthermia 1997, 13:69–82.
-
(1997)
Int J Hyperthermia
, vol.13
, pp. 69-82
-
-
Hentschel, M.1
Mirtsch, S.2
Jordan, A.3
Wust, P.4
Vogl, T.5
Semmler, W.6
Wolf, K.J.7
Felix, R.8
-
54
-
-
34249858538
-
Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: results of a prospective phase I trial
-
Johannsen M, Gneveckow U, Taymoorian K, Thiesen B, Waldofner N, Scholz R, Jung K, Jordan A, Wust P, Loening SA. Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: results of a prospective phase I trial. Int J Hyperthermia 2007, 23:315–323.
-
(2007)
Int J Hyperthermia
, vol.23
, pp. 315-323
-
-
Johannsen, M.1
Gneveckow, U.2
Taymoorian, K.3
Thiesen, B.4
Waldofner, N.5
Scholz, R.6
Jung, K.7
Jordan, A.8
Wust, P.9
Loening, S.A.10
-
55
-
-
79959846524
-
Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme
-
Maier-Hauff K, Ulrich F, Nestler D, Niehoff H, Wust P, Thiesen B, Orawa H, Budach V, Jordan A. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme. J Neurooncol 2011, 103:317–324.
-
(2011)
J Neurooncol
, vol.103
, pp. 317-324
-
-
Maier-Hauff, K.1
Ulrich, F.2
Nestler, D.3
Niehoff, H.4
Wust, P.5
Thiesen, B.6
Orawa, H.7
Budach, V.8
Jordan, A.9
-
56
-
-
45849139679
-
Plasmonic photothermal therapy (PPTT) using gold nanoparticles
-
Huang X, Jain PK, El-Sayed IH, El-Sayed MA. Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med Sci 2008, 23:217–228.
-
(2008)
Lasers Med Sci
, vol.23
, pp. 217-228
-
-
Huang, X.1
Jain, P.K.2
El-Sayed, I.H.3
El-Sayed, M.A.4
-
57
-
-
2642535307
-
Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery
-
Paciotti GF, Myer L, Weinreich D, Goia D, Pavel N, McLaughlin RE, Tamarkin L. Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery. Drug Deliv 2004, 11:169–183.
-
(2004)
Drug Deliv
, vol.11
, pp. 169-183
-
-
Paciotti, G.F.1
Myer, L.2
Weinreich, D.3
Goia, D.4
Pavel, N.5
McLaughlin, R.E.6
Tamarkin, L.7
-
58
-
-
78650348824
-
Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine
-
Libutti SK, Paciotti GF, Byrnes AA, Alexander HR Jr, Gannon WE, Walker M, Seidel GD, Yuldasheva N, Tamarkin L. Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res 2010, 16:6139–6149.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 6139-6149
-
-
Libutti, S.K.1
Paciotti, G.F.2
Byrnes, A.A.3
Alexander, H.R.4
Gannon, W.E.5
Walker, M.6
Seidel, G.D.7
Yuldasheva, N.8
Tamarkin, L.9
-
59
-
-
84867095663
-
Nanoscale radiotherapy with hafnium oxide nanoparticles
-
Maggiorella L, Barouch G, Devaux C, Pottier A, Deutsch E, Bourhis J, Borghi E, Levy L. Nanoscale radiotherapy with hafnium oxide nanoparticles. Future Oncol 2012, 8:1167–1181.
-
(2012)
Future Oncol
, vol.8
, pp. 1167-1181
-
-
Maggiorella, L.1
Barouch, G.2
Devaux, C.3
Pottier, A.4
Deutsch, E.5
Bourhis, J.6
Borghi, E.7
Levy, L.8
-
60
-
-
0030016915
-
Lipid formulations of amphotericin B: recent progress and future directions
-
Hiemenz JW, Walsh TJ. Lipid formulations of amphotericin B: recent progress and future directions. Clin Infect Dis 1996, 22(Suppl 2):S133–S144.
-
(1996)
Clin Infect Dis
, vol.22
, pp. S133-S144
-
-
Hiemenz, J.W.1
Walsh, T.J.2
-
61
-
-
7344264567
-
Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia
-
White MH, Bowden RA, Sandler ES, Graham ML, Noskin GA, Wingard JR, Goldman M, van Burik JA, McCabe A, Lin JS, et al. Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia. Clin Infect Dis 1998, 27:296–302.
-
(1998)
Clin Infect Dis
, vol.27
, pp. 296-302
-
-
White, M.H.1
Bowden, R.A.2
Sandler, E.S.3
Graham, M.L.4
Noskin, G.A.5
Wingard, J.R.6
Goldman, M.7
van Burik, J.A.8
McCabe, A.9
Lin, J.S.10
-
62
-
-
77955872446
-
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis
-
Caminero JA, Sotgiu G, Zumla A, Migliori GB. Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis. Lancet Infect Dis 2010, 10:621–629.
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 621-629
-
-
Caminero, J.A.1
Sotgiu, G.2
Zumla, A.3
Migliori, G.B.4
-
63
-
-
23844474727
-
Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients
-
Canton R, Cobos N, de Gracia J, Baquero F, Honorato J, Gartner S, Alvarez A, Salcedo A, Oliver A, Garcia-Quetglas E, et al. Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients. Clin Microbiol Infect 2005, 11:690–703.
-
(2005)
Clin Microbiol Infect
, vol.11
, pp. 690-703
-
-
Canton, R.1
Cobos, N.2
de Gracia, J.3
Baquero, F.4
Honorato, J.5
Gartner, S.6
Alvarez, A.7
Salcedo, A.8
Oliver, A.9
Garcia-Quetglas, E.10
-
64
-
-
41149105955
-
Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections
-
Meers P, Neville M, Malinin V, Scotto AW, Sardaryan G, Kurumunda R, Mackinson C, James G, Fisher S, Perkins WR. Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections. J Antimicrob Chemother 2008, 61:859–868.
-
(2008)
J Antimicrob Chemother
, vol.61
, pp. 859-868
-
-
Meers, P.1
Neville, M.2
Malinin, V.3
Scotto, A.W.4
Sardaryan, G.5
Kurumunda, R.6
Mackinson, C.7
James, G.8
Fisher, S.9
Perkins, W.R.10
-
65
-
-
84881542878
-
Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection
-
Clancy JP, Dupont L, Konstan MW, Billings J, Fustik S, Goss CH, Lymp J, Minic P, Quittner AL, Rubenstein RC, et al. Phase II studies of nebulised Arikace in CF patients with Pseudomonas aeruginosa infection. Thorax 2013, 68:818–825.
-
(2013)
Thorax
, vol.68
, pp. 818-825
-
-
Clancy, J.P.1
Dupont, L.2
Konstan, M.W.3
Billings, J.4
Fustik, S.5
Goss, C.H.6
Lymp, J.7
Minic, P.8
Quittner, A.L.9
Rubenstein, R.C.10
-
66
-
-
0033984148
-
The reproductive and developmental toxicity of the antifungal drug Nyotran (liposomal nystatin) in rats and rabbits
-
Larson JL, Wallace TL, Tyl RW, Marr MC, Myers CB, Cossum PA. The reproductive and developmental toxicity of the antifungal drug Nyotran (liposomal nystatin) in rats and rabbits. Toxicol Sci 2000, 53:421–429.
-
(2000)
Toxicol Sci
, vol.53
, pp. 421-429
-
-
Larson, J.L.1
Wallace, T.L.2
Tyl, R.W.3
Marr, M.C.4
Myers, C.B.5
Cossum, P.A.6
-
67
-
-
77649116837
-
Safety, tolerability, and pharmacokinetics of SPL7013 gel (VivaGel): a dose ranging, phase I study
-
O'Loughlin J, Millwood IY, McDonald HM, Price CF, Kaldor JM, Paull JR. Safety, tolerability, and pharmacokinetics of SPL7013 gel (VivaGel): a dose ranging, phase I study. Sex Transm Dis 2010, 37:100–104.
-
(2010)
Sex Transm Dis
, vol.37
, pp. 100-104
-
-
O'Loughlin, J.1
Millwood, I.Y.2
McDonald, H.M.3
Price, C.F.4
Kaldor, J.M.5
Paull, J.R.6
-
68
-
-
80052844387
-
SPL7013 Gel (VivaGel(R)) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans
-
Price CF, Tyssen D, Sonza S, Davie A, Evans S, Lewis GR, Xia S, Spelman T, Hodsman P, Moench TR, et al. SPL7013 Gel (VivaGel(R)) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans. PLoS One 2011, 6:e24095.
-
(2011)
PLoS One
, vol.6
-
-
Price, C.F.1
Tyssen, D.2
Sonza, S.3
Davie, A.4
Evans, S.5
Lewis, G.R.6
Xia, S.7
Spelman, T.8
Hodsman, P.9
Moench, T.R.10
-
69
-
-
79251604177
-
A phase I randomized placebo controlled trial of the safety of 3% SPL7013 Gel (VivaGel(R)) in healthy young women administered twice daily for 14 days
-
Cohen CR, Brown J, Moscicki AB, Bukusi EA, Paull JR, Price CF, Shiboski S. A phase I randomized placebo controlled trial of the safety of 3% SPL7013 Gel (VivaGel(R)) in healthy young women administered twice daily for 14 days. PLoS One 2011, 6:e16258.
-
(2011)
PLoS One
, vol.6
-
-
Cohen, C.R.1
Brown, J.2
Moscicki, A.B.3
Bukusi, E.A.4
Paull, J.R.5
Price, C.F.6
Shiboski, S.7
-
70
-
-
84949565743
-
Antimicrobial evaluation of quaternary ammonium polyethyleneimine nanoparticles against clinical isolates of pathogenic bacteria
-
Ortega A, Farah S, Tranque P, Ocana AV, Nam-Cha SH, Beyth N, Gomez-Roldan C, Perez-Tanoira R, Domb AJ, Perez-Martinez FC, et al. Antimicrobial evaluation of quaternary ammonium polyethyleneimine nanoparticles against clinical isolates of pathogenic bacteria. IET Nanobiotechnol 2015, 9:342–348.
-
(2015)
IET Nanobiotechnol
, vol.9
, pp. 342-348
-
-
Ortega, A.1
Farah, S.2
Tranque, P.3
Ocana, A.V.4
Nam-Cha, S.H.5
Beyth, N.6
Gomez-Roldan, C.7
Perez-Tanoira, R.8
Domb, A.J.9
Perez-Martinez, F.C.10
-
71
-
-
84933181273
-
Characterization of the release profile of doxycycline by PLGA microspheres adjunct to non-surgical periodontal therapy
-
Moura LA, Ribeiro FV, Aiello TB, Duek EA, Sallum EA, Nociti Junior FH, Casati MZ, Sallum AW. Characterization of the release profile of doxycycline by PLGA microspheres adjunct to non-surgical periodontal therapy. J Biomater Sci Polym Ed 2015, 26:573–584.
-
(2015)
J Biomater Sci Polym Ed
, vol.26
, pp. 573-584
-
-
Moura, L.A.1
Ribeiro, F.V.2
Aiello, T.B.3
Duek, E.A.4
Sallum, E.A.5
Nociti Junior, F.H.6
Casati, M.Z.7
Sallum, A.W.8
-
72
-
-
84929297957
-
Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: a systematic review and meta-analysis of randomized controlled trials
-
Kryst J, Kawalec P, Pilc A. Efavirenz-based regimens in antiretroviral-naive HIV-infected patients: a systematic review and meta-analysis of randomized controlled trials. PLoS One 2015, 10:e0124279.
-
(2015)
PLoS One
, vol.10
-
-
Kryst, J.1
Kawalec, P.2
Pilc, A.3
-
73
-
-
84934897723
-
Silver nanoparticles as potential antibacterial agents
-
Franci G, Falanga A, Galdiero S, Palomba L, Rai M, Morelli G, Galdiero M. Silver nanoparticles as potential antibacterial agents. Molecules 2015, 20:8856–8874.
-
(2015)
Molecules
, vol.20
, pp. 8856-8874
-
-
Franci, G.1
Falanga, A.2
Galdiero, S.3
Palomba, L.4
Rai, M.5
Morelli, G.6
Galdiero, M.7
-
74
-
-
84948065871
-
Modeling maternal fetal RSV F vaccine induced antibody transfer in guinea pigs
-
Glenn GM, Fries LF, Smith G, Kpamegan E, Lu H, Guebre-Xabier M, Hickman SP, Flyer D. Modeling maternal fetal RSV F vaccine induced antibody transfer in guinea pigs. Vaccine 2015, 33:6488–6492.
-
(2015)
Vaccine
, vol.33
, pp. 6488-6492
-
-
Glenn, G.M.1
Fries, L.F.2
Smith, G.3
Kpamegan, E.4
Lu, H.5
Guebre-Xabier, M.6
Hickman, S.P.7
Flyer, D.8
-
75
-
-
77957309983
-
Hepatic-directed vesicle insulin: a review of formulation development and preclinical evaluation
-
Geho WB, Geho HC, Lau JR, Gana TJ. Hepatic-directed vesicle insulin: a review of formulation development and preclinical evaluation. J Diabetes Sci Technol 2009, 3:1451–1459.
-
(2009)
J Diabetes Sci Technol
, vol.3
, pp. 1451-1459
-
-
Geho, W.B.1
Geho, H.C.2
Lau, J.R.3
Gana, T.J.4
-
76
-
-
84900821501
-
A single-blind, placebo-controlled, dose-ranging trial of oral hepatic-directed vesicle insulin add-on to oral antidiabetic treatment in patients with type 2 diabetes mellitus
-
Geho WB, Rosenberg LN, Schwartz SL, Lau JR, Gana TJ. A single-blind, placebo-controlled, dose-ranging trial of oral hepatic-directed vesicle insulin add-on to oral antidiabetic treatment in patients with type 2 diabetes mellitus. J Diabetes Sci Technol 2014, 8:551–559.
-
(2014)
J Diabetes Sci Technol
, vol.8
, pp. 551-559
-
-
Geho, W.B.1
Rosenberg, L.N.2
Schwartz, S.L.3
Lau, J.R.4
Gana, T.J.5
-
77
-
-
84907095890
-
Nanocarriers in gene therapy: a review
-
Xu H, Li Z, Si J. Nanocarriers in gene therapy: a review. J Biomed Nanotechnol 2014, 10:3483–3507.
-
(2014)
J Biomed Nanotechnol
, vol.10
, pp. 3483-3507
-
-
Xu, H.1
Li, Z.2
Si, J.3
-
78
-
-
84883118140
-
Safety and efficacy of RNAi therapy for transthyretin amyloidosis
-
Coelho T, Adams D, Silva A, Lozeron P, Hawkins PN, Mant T, Perez J, Chiesa J, Warrington S, Tranter E, et al. Safety and efficacy of RNAi therapy for transthyretin amyloidosis. N Engl J Med 2013, 369:819–829.
-
(2013)
N Engl J Med
, vol.369
, pp. 819-829
-
-
Coelho, T.1
Adams, D.2
Silva, A.3
Lozeron, P.4
Hawkins, P.N.5
Mant, T.6
Perez, J.7
Chiesa, J.8
Warrington, S.9
Tranter, E.10
-
79
-
-
84877058290
-
Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors
-
Senzer N, Nemunaitis J, Nemunaitis D, Bedell C, Edelman G, Barve M, Nunan R, Pirollo KF, Rait A, Chang EH. Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors. Mol Ther 2013, 21:1096–1103.
-
(2013)
Mol Ther
, vol.21
, pp. 1096-1103
-
-
Senzer, N.1
Nemunaitis, J.2
Nemunaitis, D.3
Bedell, C.4
Edelman, G.5
Barve, M.6
Nunan, R.7
Pirollo, K.F.8
Rait, A.9
Chang, E.H.10
-
80
-
-
84941262148
-
RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients
-
Golan T, Khvalevsky EZ, Hubert A, Gabai RM, Hen N, Segal A, Domb A, Harari G, David EB, Raskin S, et al. RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients. Oncotarget 2015, 6:24560–24570.
-
(2015)
Oncotarget
, vol.6
, pp. 24560-24570
-
-
Golan, T.1
Khvalevsky, E.Z.2
Hubert, A.3
Gabai, R.M.4
Hen, N.5
Segal, A.6
Domb, A.7
Harari, G.8
David, E.B.9
Raskin, S.10
-
81
-
-
84892741671
-
Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial
-
Fitzgerald K, Frank-Kamenetsky M, Shulga-Morskaya S, Liebow A, Bettencourt BR, Sutherland JE, Hutabarat RM, Clausen VA, Karsten V, Cehelsky J, et al. Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial. Lancet 2014, 383:60–68.
-
(2014)
Lancet
, vol.383
, pp. 60-68
-
-
Fitzgerald, K.1
Frank-Kamenetsky, M.2
Shulga-Morskaya, S.3
Liebow, A.4
Bettencourt, B.R.5
Sutherland, J.E.6
Hutabarat, R.M.7
Clausen, V.A.8
Karsten, V.9
Cehelsky, J.10
-
82
-
-
84877120847
-
First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement
-
Tabernero J, Shapiro GI, LoRusso PM, Cervantes A, Schwartz GK, Weiss GJ, Paz-Ares L, Cho DC, Infante JR, Alsina M, et al. First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov 2013, 3:406–417.
-
(2013)
Cancer Discov
, vol.3
, pp. 406-417
-
-
Tabernero, J.1
Shapiro, G.I.2
LoRusso, P.M.3
Cervantes, A.4
Schwartz, G.K.5
Weiss, G.J.6
Paz-Ares, L.7
Cho, D.C.8
Infante, J.R.9
Alsina, M.10
-
83
-
-
84905670761
-
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
-
Zuckerman JE, Gritli I, Tolcher A, Heidel JD, Lim D, Morgan R, Chmielowski B, Ribas A, Davis ME, Yen Y. Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA. Proc Natl Acad Sci USA 2014, 111:11449–11454.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 11449-11454
-
-
Zuckerman, J.E.1
Gritli, I.2
Tolcher, A.3
Heidel, J.D.4
Lim, D.5
Morgan, R.6
Chmielowski, B.7
Ribas, A.8
Davis, M.E.9
Yen, Y.10
-
84
-
-
80052627990
-
Current progress of siRNA/shRNA therapeutics in clinical trials
-
Burnett JC, Rossi JJ, Tiemann K. Current progress of siRNA/shRNA therapeutics in clinical trials. Biotechnol J 2011, 6:1130–1146.
-
(2011)
Biotechnol J
, vol.6
, pp. 1130-1146
-
-
Burnett, J.C.1
Rossi, J.J.2
Tiemann, K.3
|