Insect-specific flavivirus infection is restricted by innate immunity in the vertebrate host

Virology

Volumn 497, Issue , 2016, Pages 81-91

  Tree, Maya O ^a   McKellar, Dexter R ^a   Kieft, Kristopher J ^a   Watson, Alan M ^b   Ryman, Kate D ^b   Conway, Michael J ^a  

^a Children's Hospital of Michigan   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Dengue virus; Evolution; Flavivirus; Host adaptation; Innate immunity; Insect specific; Kamiti River virus

Indexed keywords

INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 5; INTERFERON REGULATORY FACTOR 7; VIRUS PROTEIN; INTERFERON REGULATORY FACTOR; PROTEIN BINDING; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 3; VIRAL PROTEIN; VIRUS RNA;

ADAPTATION; ANIMAL CELL; ARBOVIRUS; ARTICLE; CONTROLLED STUDY; EMBRYO CELL; FIBROBLAST; FLAVIVIRUS; FLAVIVIRUS INFECTION; HOST; INNATE IMMUNITY; INSECT SPECIFIC FLAVIVIRUS; KAMITI RIVER VIRUS; MOUSE EMBRYO; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; VERTEBRATE; VIRUS SHEDDING; ANIMAL; CELL LINE; CHEMISTRY; CHLOROCEBUS AETHIOPS; EVOLUTION; GENE INACTIVATION; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; INSECT; INSECT VECTOR; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE; TRANSMISSION; VERO CELL LINE; VIROLOGY;

ADAPTATION, BIOLOGICAL; ANIMALS; BIOLOGICAL EVOLUTION; CELL LINE; CERCOPITHECUS AETHIOPS; FLAVIVIRUS; FLAVIVIRUS INFECTIONS; GENE KNOCKOUT TECHNIQUES; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; INSECT VECTORS; INSECTS; INTERFERON REGULATORY FACTORS; PROTEIN BINDING; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA, VIRAL; TOLL-LIKE RECEPTOR 3; VERO CELLS; VERTEBRATES; VIRAL PROTEINS;

EID: 84978218424     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2016.07.005     Document Type: Article

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