Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia–reperfusion injury in rats through suppression of mitochondrial permeability transition

Journal of Pineal Research

Volumn , Issue , 2016, Pages 52-68

  Chen, Hong Hwa ^a   Chen, Yen Ta ^a   Yang, Chih Chao ^a   Chen, Kuan Hung ^a   Sung, Pei Hsun ^a   Chiang, Hsin Ju ^a   Chen, Chih Hung ^a   Chua, Sarah ^a   Chung, Sheng Ying ^a   Chen, Yi Ling ^a   Huang, Tien Hung ^a   Kao, Gour Shenq ^a   Chen, Sheng Yi ^a   Lee, Mel S ^a   Yip, Hon Kan ^a,b,c,d  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

DNA and mitochondrial damage; inflammation; liver ischemia reperfusion injury; melatonin; mitochondria; oxidative stress

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CASPASE 3; CD14 ANTIGEN; CD68 ANTIGEN; CYTOCHROME C; GELATINASE B; HISTONE H2AX; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MELATONIN; MENADIONE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; PROTEIN BAX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; THY 1 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; XRCC1 PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER ISCHEMIA; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; THERAPY EFFECT;

EID: 84978121068     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12326     Document Type: Article

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