Effects of simvastatin, rosuvastatin and pravastatin on soluble fms-like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sENG) secretion from human umbilical vein endothelial cells, primary trophoblast cells and placenta

BMC Pregnancy and Childbirth

Volumn 16, Issue 1, 2016, Pages

  Brownfoot, Fiona C ^a   Tong, Stephen ^a   Hannan, Natalie J ^a   Hastie, Roxanne ^a   Cannon, Ping ^a   Kaitu'u Lino, Tu'uhevaha J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Preeclampsia; Pregnancy; SFlt 1; Soluble endoglin; Statins

Indexed keywords

ENDOGLIN; HEME OXYGENASE 1; MESSENGER RNA; PRAVASTATIN; PROTEIN TYROSINE KINASE; ROSUVASTATIN; SIMVASTATIN; SOLUBLE FMS LIKE TYROSINE KINASE 1; UNCLASSIFIED DRUG; ENG PROTEIN, HUMAN; FLT1 PROTEIN, HUMAN; HMOX1 PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLACENTA PROTEIN; VASCULOTROPIN RECEPTOR 1;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPLANT; FEMALE; HEME OXYGENASE 1 GENE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; PLACENTA; PREECLAMPSIA; PRIMARY CELL; PROTEIN SECRETION; TROPHOBLAST; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; CYTOLOGY; DRUG EFFECTS; PREGNANCY; SECRETION (PROCESS);

ENDOGLIN; FEMALE; HEME OXYGENASE-1; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; PLACENTA; PRAVASTATIN; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; ROSUVASTATIN CALCIUM; SIMVASTATIN; TROPHOBLASTS; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84978091926     PISSN: None     EISSN: 14712393     Source Type: Journal    
DOI: 10.1186/s12884-016-0902-3     Document Type: Article

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