The association between helicobacter pylori infection and inflammatory bowel disease based on meta-analysis

United European Gastroenterology Journal

Volumn 3, Issue 6, 2015, Pages 539-550

  Rokkas, T ^a   Gisbert, J P ^b   Niv, Y ^c   O'Morain C ^d  

^a HENRY DUNANT HOSPITAL   (Greece)

^b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^c TEL AVIV UNIVERSITY   (Israel)

^d ADELAIDE AND MEATH HOSPITAL   (Ireland)

Author keywords

Crohn s disease; Helicobacter pylori; Inflammatory bowel disease; Meta analysis; Ulcerative colitis

Indexed keywords

ARTICLE; BIBLIOGRAPHIC DATABASE; CLINICAL EVALUATION; CLINICAL FEATURE; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE TRANSMISSION; EVIDENCE BASED PRACTICE; HELICOBACTER INFECTION; HUMAN; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; INFORMATION PROCESSING; OBSERVATIONAL STUDY; PREVALENCE; PRIORITY JOURNAL; QUALITATIVE RESEARCH; RISK ASSESSMENT; SYSTEMATIC REVIEW (TOPIC); ULCERATIVE COLITIS;

EID: 84977938192     PISSN: 20506406     EISSN: 20506414     Source Type: Journal    
DOI: 10.1177/2050640615580889     Document Type: Article

References (75)

1. Loftus EV. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 2004; 126: 1504-1517.
2. Thia KT, Loftus EV, Sandborn WJ, et al. An update on the epidemiology of inflammatory bowel disease in Asia. Am J Gastroenterol 2008; 103: 3167-3182.
3. Baumgart DC, Bernstein CN, Abbas Z, et al. IBD Around the world: Comparing the epidemiology, diagnosis, and treatment: Proceedings of the World Digestive Health Day 2010-Inflammatory Bowel Disease Task Force meeting. Inflamm Bowel Dis 2011; 17: 639-644.
4. Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012; 142: 46-54.
5. Bloomfield SF, Stanwell-Smith R, Crevel RW, et al. Too clean, or not too clean: The hygiene hypothesis and home hygiene. Clin Exp Allergy 2006; 36: 402-425.
6. Koloski NA, Bret L and Radford-Smith G. Hygiene hypothesis in inflammatory bowel disease: A critical review of the literature. World J Gastroenterol 2008; 14: 165-173.
7. Valle J, Kekki M, Sipponen P, et al. Long-term course and consequences of Helicobacter pylori gastritis. Results of a 32-year follow-up study. Scand J Gastroenterol 1996; 31: 546-550.
8. Sonnenberg A. Review article: Historic changes of Helicobacter pylori-associated diseases. Aliment Pharmacol Ther 2013; 38: 329-342.
9. Smythies LE, Waites KB, Lindsey JR, et al. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFNgamma, gene-deficient mice. J Immunol 2000; 165: 1022-1029.
10. Di Tommaso A, Xiang Z, Bugnoli M, et al. Helicobacter pylori-specific CD4þ T-cell clones from peripheral blood and gastric biopsies. Infect Immun 1995; 63: 1102-1106.
11. Meyer F, Wilson KT and James SP. Modulation of innate cytokine responses by products of Helicobacter pylori. Infect Immun 2000; 68: 6265-6272.
12. van Amsterdam K, van Vliet AH, Kusters JG, et al. Of microbe and man: Determinants of Helicobacter pylori-related diseases. FEMS Microbiol Rev 2006; 30: 131-156.
13. Ram M, Barzilai O, Shapira Y, et al. Helicobacter pylori serology in autoimmune diseases-fact or fiction? Clin Chem Lab Med 2013; 51: 1075-1082.
14. Chen Y and Blaser MJ. Helicobacter pylori colonization is inversely associated with childhood asthma. J Infect Dis 2008; 198: 553-560.
15. Reibman J, Marmor M, Filner J, et al. Asthma is inversely associated with Helicobacter pylori status in an urban population. PLoS One 2008; 2: e4060.
16. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: Explanation and elaboration. J Clin Epidemiol 2009; 62: e1-e34.
17. Mantel N and Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Nat Cancer Inst 1959; 22: 719-748.
18. DerSimonian R and Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-188.
19. Cochran WG. The combination of estimates from different experiments. Biometrics 1954; 8: 101-129.
20. Higgins JP and Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-1558.
21. Higgins JP, Thompson SG and Deeks JJ. Measuring inconsistency in meta-analysis. BMJ 2003; 327: 557-560.
22. Sutton AJ, Abrams KR, Jones DR, et al. In: Methods for meta-analysis in medical research. New York: John Wiley & Sons Ltd, 2000.
23. Borenstein M, Hedges LV, Higgins JPT, et al. Introduction to meta-analysis. New York: John Wiley & Sons Ltd.
24. Copas JB and Shi JQ. A sensitivity analysis for publication bias in systematic reviews. Stat Methods Med Res 2001; 10: 251-265.
25. Begg CB and Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088-1101.
26. Egger M, Davey Smith G, Schneider M, et al. Bias in meta-analysis detected by a simple graphical test. BMJ 1997; 315: 29-34.
27. Duval S and Tweedie R. Trim and fill: A simple funnel plot-based method of testing and in meta-analysis. Biometrics 2000; 56: 455-463.
28. el-Omar E, Penman I, Cruikshank G, et al. Low prevalence of Helicobacter pylori in inflammatory bowel disease: Association with sulfasalazine. Gut 1994; 35: 1385-1388.
29. Mantzaris GJ, Archavlis E, Zografos C, et al. Low prevalence of Helicobacter pylori in inflammatory bowel disease: Association with sulfasalazine. Am J Gastroenterol 1995; 90: 1900.
30. Halme L, Rautelin H, Leidenius M, et al. Inverse correlation between Helicobacter pylori infection and inflammatory bowel disease. J Clin Pathol 1996; 49: 65-67.
31. Meining A, Bayerdorffer E, Bastlein E, et al. Focal inflammatory infiltrations in gastric biopsy specimens are suggestive of Crohn’s disease. Scand J Gastroenterol 1997; 32: 813-818.
32. Oberhuber G, Puspok A, Oesterreicher C, et al. Focally enhanced gastritis: A frequent type of gastritis in patients with Crohn’s disease. Gastroenterology 1997; 112: 698-706.
33. Parente F, Molteni P, Bollani S, et al. Prevalence of Helicobacter pylori infection and related upper gastro-intestinal lesions in patients with inflammatory bowel disease. A cross-sectional study with matching. Scand J Gastroenterol 1997; 32: 1140-1146.
34. Wagtmans MJ, Witte AMC, Taylor DR, et al. Low seroprevalence of Helicobacter pylori antibodies in historical sera of patients with Crohn’s disease. Scand J Gastroenterol 1997; 32: 712-718.
35. D’Inca R, Sturniolo G, Cassaro M, et al. Prevalence of upper gastrointestinal lesions and Helicobacter pylori infection in Crohn’s disease. Dig Dis Sci 1998; 43: 988-992.
36. Duggan AE, Usmani I, Neal KR, et al. Appendicectomy, childhood hygiene, Helicobacter pylori status, and risk of inflammatory bowel disease: A case control study. Gut 1998; 43: 494-498.
37. Pearce CB, Duncan HD, Timmis L, et al. Assessment of the prevalence of infection with Helicobacter pylori in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol 2000; 12: 439-443.
38. Parente F, Cucino C, Bollani S, et al. Focal gastric inflammatory infiltrates in inflammatory bowel diseases: Prevalence, immunohistochemical characteristics and diagnostic role. Am J Gastroenterol 2000; 95: 705-711.
39. Matsumura M, Matsui T, Hatakeyama S, et al. Prevalence of Helicobacter pylori infection and correlation between severity of upper gastrointestinal lesions and H. pylori infection in Japanese patients with Crohn’s disease. J Gastroenterol 2001; 36: 740-747.
40. Parlak E, Ulker A, Disibeyaz S, et al. There is no significant increase in the incidence of Helicobacter pylori infection in patients with inflammatory bowel disease in Turkey. J Clin Gastroenterol 2001; 33: 87-88.
41. Vare PO, Heikius B, Silvennoinen R, et al. Seroprevalence of Helicobacter pylori infection in inflammatory bowel disease: Is Helicobacter pylori infection a protective factor? Scand J Gastroenterol 2001; 36: 1295-1300.
42. Feeney MA, Murphy F, Clegg AJ, et al. A case-control study of childhood environmental risk factors for the development of inflammatory bowel disease. Eur J Gastroenterol Hepatol 2002; 14: 529-534.
43. Furusu H, Murase K, Nishida Y, et al. Accumulation of mast cells and macrophages in focal active gastritis of patients with Crohn’s disease. Hepatogastroenterology 2002; 49: 639-643.
44. Guslandi M, Fanti L and Testoni PA. Helicobacter pylori seroprevalence in Crohn’s disease: Lack of influence by pharmacological treatment. Hepatogastroenterology 2002; 49: 1296-1297.
45. Pascasio JM, Hammond S and Qualman SJ. Recognition of Crohn disease on incidental gastric biopsy in child-hood. Pediatr Dev Pathol 2003; 6: 209-214.
46. Piodi LP, Bardella M, Rocchia C, et al. Possible protective effect of 5-aminosalicylic acid on Helicobacter pylori infection in patients with inflammatory bowel disease. J Clin Gastroenterol 2003; 36: 22-25.
47. Triantafillidis JK, Tzourmakliotis D, Peros G, et al. Serum gastrin levels in patients with inflammatory bowel disease. Hepatogastroenterology 2003; 50(Suppl 2): 315-317.
48. Oliveira AG, Sanna MGP, Rocha GA, et al. Helicobacter species in the intestinal mucosa of patients with ulcerative colitis. J Clin Microbiol 2004; 42: 384-386.
49. Pronai L, Schandl L, Orosz Z, et al. Lower prevalence of Helicobacter pylori infection in patients with inflammatory bowel disease but not with chronic obstructive pulmonary disease-antibiotic use in the history does not play a significant role. Helicobacter 2004; 9: 278-283.
50. Oliveira AG, Rocha GA, Rocha AMC, et al. Isolation of Helicobacter pylori from the intestinal mucosa of patients with Crohn’s disease. Helicobacter 2006; 11: 2-9.
51. Sladek M, Jedynak-Wasowicz U, Wedrychowicz A, et al. The low prevalence of Helicobacter pylori gastritis in newly diagnosed inflammatory bowel disease children and adolescent [article in Polish]. Przegl Lek 2007; 64(Suppl 3): 65-67.
52. Ando T, Watanabe O, Ishiguro K, et al. Relationships between Helicobacter pylori infection status, endoscopic, histopathological findings, and cytokine production in the duodenum of Crohn’s disease patients. J Gastroenterol Hepatol 2008; 23(Suppl 2): S193-S197.
53. Lidar M, Langevitz P, Barzilai O, et al. Infectious serologies and autoantibodies in inflammatory bowel disease: Insinuations at a true pathogenic role. Ann N Y Acad Sci 2009; 1173: 640-648.
54. Song MJ, Park DI, Hwang SJ, et al. The prevalence of Helicobacter pylori infection in Korean patients with inflammatory bowel disease, a multicenter study [article in Korean]. Korean J Gastroenterol 2009; 53: 341-347.
55. Garza-Gonzalez E, Perez-Perez GI, Mendoza-Ibarra SI, et al. Genetic risk factors for inflammatory bowel disease in a North-eastern Mexican population. Int J Immunogenet 2010; 37: 355-359.
56. Pellicano R, Bresso F, Demarchi B, et al. Prevalence of Helicobacter pylori infection in patients with inflammatory bowel disease: Pilot study. Rev Esp Enferm Dig 2010; 102: 675-666; author reply 676.
57. Varas-Lorenzo MJ and Munoz-Agel F. Is Helicobacter pylori active infection increased or decreased in Crohn’s disease? [article in Spanish]. Rev Esp Enferm Dig 2010; 102: 509-510.
58. Zhang S, Zhong B, Chao K, et al. Role of Helicobacter species in Chinese patients with inflammatory bowel disease. J Clin Microbiol 2011; 49: 1987-1989.
59. Jin X, Chen YP, Chen SH, et al. Association between Helicobacter pylori infection and ulcerative colitis-a case control study from China. Int J Med Sci 2013; 10: 1479-1484.
60. Xiang Z, Chen YP, Ye YF, et al. Helicobacter pylori and Crohn’s disease: A retrospective single-center study from China. World J Gastroenterol 2013; 19: 4576-4581.
61. Atherton JC and Blaser MJ. Helicobacter pylori infections. Harrison’s principles of internal medicine, 16th ed. New York: McGraw-Hill, p 886.
62. Luther J, Dave M, Higgins PD, et al. Association between Helicobacter pylori infection and inflammatory bowel disease: A meta-analysis and systematic review of the literature. Inflamm Bowel Dis 2010; 16: 1077-1084.
63. Sonneberg A and Genta RM. Low prevalence of Helicobacter pylori infection among patients with inflammatory bowel disease. Aliment Pharmacol Ther 2012; 35: 469-476.
64. Triantafillidis JK, Gikas A and Merikas E. Treatment of inflammatory bowel disease patients with anti-TNF-a factors and immunosuppressives do not influence the prevalence of Helicobacter pylori infection. Indian J Gastroenterol 2014; 33: 383-384.
65. Arnold IC, Hitzler I and Muller A. The immunomodulatory properties of Helicobacter pylori confer protection against allergic and chronic inflammatory disorders. Front Cell Inf Microbiol 2012; 2: 10.
66. Papamichael K, Konstantopoulos P and Mantzaris GI. Helicobacter pylori infection and inflammatory bowel disease: Is there a link? World J Gastroenterol 2014; 20: 6374-6385.
67. Kao JY, Rathinavelu S and Eaton KA. Helicobacter pylori-secreted factors inhibit dendritic cell IL-12 secretion: A mechanism of ineffective host defense. Am J Physiol Gastrointest Liver Physiol 2006; 291: G73-G81.
68. Paziak-Domanska B, Chmiela M, Jarosinska A, et al. Potential role of CagA in the inhibition of T cell reactivity in Helicobacter pylori infections. Cell Immunol 2000; 202: 136-139.
69. Gerbert B, Fischer W and Haas R. The Helicobacter pylori vacuolating cytotoxin: From cellular vacuolation to immunosuppressive activities. Rev Physiol Biochem Pharmacol 2004; 152: 205-202.
70. Rad R, Brenner L, Bauer S, et al. CD25þ/Foxp3þ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology 2006; 131: 525-537.
71. Lundgren A, Suri-Payer E, Enarsson K, et al. Helicobacter pylori-specific CD4þ CD25þ high regulatory T cells suppress memory T-cell responses to H. pylori in infected individuals. Infect Immun 2003; 1: 1755-1762.
72. Higgins PD, Johnson LA, Luther J, et al. Prior Helicobacter pylori infection ameliorates Salmonella typhimurium-induced colitis: Mucosal crosstalk between stomach and distal intestine. Inflamm Bowel Dis 2011; 17: 1398-1408.
73. Luther J, Owyang SY, Takeuchi T, et al. Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis. Gut 2011; 60: 1479-1486.
74. Chen Y and Blaser MJ. Inverse associations of Helicobacter pylori with asthma and allergy. Arch Intern Med 2007; 167: 821-827.
75. Cover TL and Blaser MJ. Helicobacter pylori in health and disease. Gastroenterology 2009; 136: 1863-1873.