Staphylococcal LTA-Induced miR-143 Inhibits Propionibacterium acnes-Mediated Inflammatory Response in Skin

Journal of Investigative Dermatology

Volumn 136, Issue 3, 2016, Pages 621-630

  Xia, Xiaoli ^a   Li, Zhiheng ^a   Liu, Kewei ^a   Wu, Yelin ^a   Jiang, Deming ^a   Lai, Yuping ^a  

^a EAST CHINA NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; INTERLEUKIN 6; LIPOTEICHOIC ACID; MICRORNA 143; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; LIPOPOLYSACCHARIDE; MICRORNA; MIRN143 MICRORNA, MOUSE; TEICHOIC ACID; TLR2 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMATITIS; EAR; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VIVO STUDY; KERATINOCYTE; MACROPHAGE; MICROBIAL ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN TARGETING; RNA ANALYSIS; RNA STABILITY; STAPHYLOCOCCUS EPIDERMIDIS; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; GENETICS; METABOLISM; MICROBIOLOGY; PATHOPHYSIOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; DERMATITIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; KERATINOCYTES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICRORNAS; MODELS, ANIMAL; PROPIONIBACTERIUM ACNES; REAL-TIME POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS EPIDERMIDIS; TEICHOIC ACIDS; TOLL-LIKE RECEPTOR 2;

EID: 84977765701     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1016/j.jid.2015.12.024     Document Type: Article

References (33)

1. Ambros, V., The functions of animal microRNAs. Nature 431 (2004), 350–355.
2. Baltimore, D., Boldin, M.P., O'connell, R.M., Rao, D.S., Taganov, K.D., MicroRNAs: new regulators of immune cell development and function. Nat Immunol 9 (2008), 839–845.
3. Bartel, D.P., MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004), 281–297.
4. Ceppi, M., Pereira, P.M., Dunand-sauthier, I., Barras, E., Reith, W., Santos, M.A., et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci USA 106 (2009), 2735–2740.
5. Ceribelli, A., Satoh, M., Chan, E.K., MicroRNAs and autoimmunity. Curr Opin Immunol 24 (2012), 686–691.
6. Cogen, A.L., Yamasaki, K., Sanchez, K.M., Dorschner, R.A., Lai, Y., MacLeod, D.T., et al. Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis: a normal resident of the skin. J Invest Dermatol 130 (2010), 192–200.
7. Fitz-gibbon, S., Tomida, S., Chiu, B.H., Nguyen, L., Du, C., Liu, M., et al. Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J Invest Dermatol 133 (2013), 2152–2160.
8. Fleming, A., On the etiology of acne vulgaris and its treatment by vaccines. Lancet 173 (1909), 1035–1038.
9. Gollnick, H., Current concepts of the pathogenesis of acne: implications for drug treatment. Drugs 63 (2003), 1579–1596.
10. Greene, C.M., Gaughan, K.P., microRNAs in asthma: potential therapeutic targets. Curr Opin Pulm Med 19 (2013), 66–72.
11. Guo, H., Chen, Y., Hu, X., Qian, G., Ge, S., Zhang, J., The regulation of toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells. Mol Cancer, 12, 2013, 77.
12. Jugeau, S., Tenaud, I., Knol, A.C., Jarrousse, V., Quereux, G., Khammari, A., et al. Induction of toll-like receptors by Propionibacterium acnes. Br J Dermatol 153 (2005), 1105–1113.
13. Kim, J., Ochoa, M.T., Krutzik, S.R., Takeuchi, O., Uematsu, S., Legaspi, A.J., et al. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol 169 (2002), 1535–1541.
14. Kurokawa, I., Danby, F.W., Ju, Q., Wang, X., Xiang, L.F., Xia, L., et al. New developments in our understanding of acne pathogenesis and treatment. Experimental dermatology 18 (2009), 821–832.
15. Lai, Y., Cogen, A.L., Radek, K.A., Park, H.J., Macleod, D.T., Leichtle, A., et al. Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections. J Invest Dermatol 130 (2010), 2211–2221.
16. Lai, Y., Di nardo, A., Nakatsuji, T., Leichtle, A., Yang, Y., Cogen, A.L., et al. Commensal bacteria regulate toll-like receptor 3-dependent inflammation after skin injury. Nat Med 15 (2009), 1377–1382.
17. Lai, Y., Li, D., Li, C., Muehleisen, B., Radek, K.A., Park, H.J., et al. The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury. Immunity 37 (2012), 74–84.
18. Leeming, J.P., Holland, K.T., Cuncliffe, W.J., The microbial colonization of inflamed acne vulgaris lesions. Br J Dermatol 118 (1988), 203–208.
19. Li, D., Lei, H., Li, Z., Li, H., Wang, Y., Lai, Y., A novel lipopeptide from skin commensal activates TLR2/CD36-p38 MAPK signaling to increase antibacterial defense against bacterial infection. PLoS One, 8, 2013, e58288.
20. Lu, L.F., Thai, T.H., Calado, D.P., Chaudhry, A., Kubo, M., Tanaka, K., et al. Foxp3-dependent microRNA155 confers competitive fitness to regulatory T cells by targeting SOCS1 protein. Immunity 30 (2009), 80–91.
21. Lyte, P., Sur, R., Nigam, A., Southall, M.D., Heat-killed Propionibacterium acnes is capable of inducing inflammatory responses in skin. Exp Dermatol 18 (2009), 1070–1072.
22. Nishijima, S., Kurokawa, I., Katoh, N., Watanabe, K., The bacteriology of acne vulgaris and antimicrobial susceptibility of Propionibacterium acnes and Staphylococcus epidermidis isolated from acne lesions. J Dermatol 27 (2000), 318–323.
23. O'connell, R.M., Chaudhuri, A.A., Rao, D.S., Baltimore, D., Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 106 (2009), 7113–7118.
24. O'connell, R.M., Rao, D.S., Baltimore, D., microRNA regulation of inflammatory responses. Annu Rev Immunol 30 (2012), 295–312.
25. Shibata, M., Katsuyama, M., Onodera, T., Ehama, R., Hosoi, J., Tagami, H., et al. Glucocorticoids enhance toll-like receptor 2 expression in human keratinocytes stimulated with Propionibacterium acnes or proinflammatory cytokines. J Invest Dermatol 129 (2009), 375–382.
26. Strauss, J.S., Kligman, A.M., The pathologic dynamics of acne vulgaris. Arch Dermatol 82 (1960), 779–790.
27. Taganov, K.D., Boldin, M.P., Chang, K.J., Baltimore, D., NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103 (2006), 12481–12486.
28. Teng, Y., Zhang, R., Liu, C., Zhou, L., Wang, H., Zhuang, W., et al. miR-143 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients by targeting IL13Ralpha1. Biochem Biophys Res Commun 457 (2015), 58–64.
29. Vowels, B.R., Yang, S., Leyden, J.J., Induction of proinflammatory cytokines by a soluble factor of Propionibacterium acnes: implications for chronic inflammatory acne. Infect Immun 63 (1995), 3158–3165.
30. Wang, Y., Kuo, S., Shu, M., Yu, J., Huang, S., Dai, A., et al. Staphylococcus epidermidis in the human skin microbiome mediates fermentation to inhibit the growth of Propionibacterium acnes: implications of probiotics in acne vulgaris. Appl Microbiol Biotechnol 98 (2014), 411–424.
31. Weidenmaier, C., Kokai-kun, J.F., Kristian, S.A., Chanturiya, T., Kalbacher, H., Gross, M., et al. Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosocomial infections. Nat Med 10 (2004), 243–245.
32. Xie, W., Li, Z., Li, M., Xu, N., Zhang, Y., miR-181a and inflammation: miRNA homeostasis response to inflammatory stimuli in vivo. Biochem Biophys Res Commun 430 (2013), 647–652.
33. Zouboulis, C., Eady, A., Philpott, M., Goldsmith, L.A., Orfanos, C., Cunliffe, W.C., et al. What is the pathogenesis of acne?. Exper Dermatol 14 (2005), 143–152.