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Volumn 17, Issue 6, 2016, Pages 535-542

Cancer Stem Cells, Epithelial to Mesenchymal Markers, and Circulating Tumor Cells in Small Cell Lung Cancer

Author keywords

c MET; CSCs; CTCs; EMT; SCLC

Indexed keywords

CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 8; EPITHELIAL CELL ADHESION MOLECULE; HERMES ANTIGEN; SCATTER FACTOR RECEPTOR; TRANSCRIPTION FACTOR SOX2; TUMOR MARKER; UVOMORULIN; VIMENTIN;

EID: 84977657615     PISSN: 15257304     EISSN: 19380690     Source Type: Journal    
DOI: 10.1016/j.cllc.2016.05.015     Document Type: Article
Times cited : (34)

References (36)
  • 1
    • 33750603100 scopus 로고    scopus 로고
    • Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the Surveillance, Epidemiologic, and End Results database
    • 1 Govindan, R., Page, N., Morgensztern, D., et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the Surveillance, Epidemiologic, and End Results database. J Clin Oncol 24 (2006), 4539–4544.
    • (2006) J Clin Oncol , vol.24 , pp. 4539-4544
    • Govindan, R.1    Page, N.2    Morgensztern, D.3
  • 2
    • 77954142509 scopus 로고    scopus 로고
    • Radiotherapy in small-cell lung cancer: where should it go?
    • 2 Paumier, A., Le Pechoux, C., Radiotherapy in small-cell lung cancer: where should it go?. Lung Cancer 69 (2010), 133–140.
    • (2010) Lung Cancer , vol.69 , pp. 133-140
    • Paumier, A.1    Le Pechoux, C.2
  • 3
    • 77956265766 scopus 로고    scopus 로고
    • Small cell lung cancer: past, present, and future
    • 3 Rodriguez, E., Lilenbaum, R.C., Small cell lung cancer: past, present, and future. Curr Oncol Rep 12 (2010), 327–334.
    • (2010) Curr Oncol Rep , vol.12 , pp. 327-334
    • Rodriguez, E.1    Lilenbaum, R.C.2
  • 4
    • 0037247903 scopus 로고    scopus 로고
    • American College of Chest Physicians. Small cell lung cancer
    • 4 Simon, G.R., Wagner, H., American College of Chest Physicians. Small cell lung cancer. Chest 123:1 suppl (2003), 259S–271S.
    • (2003) Chest , vol.123 , Issue.1 , pp. 259S-271S
    • Simon, G.R.1    Wagner, H.2
  • 5
    • 34848884868 scopus 로고    scopus 로고
    • American College of Chest Physicians. Management of small cell lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition)
    • 5 Simon, G.R., Turrisi, A., American College of Chest Physicians. Management of small cell lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 132:3 suppl (2007), 324S–339S.
    • (2007) Chest , vol.132 , Issue.3 , pp. 324S-339S
    • Simon, G.R.1    Turrisi, A.2
  • 7
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • 7 Lamouille, S., Xu, J., Derynck, R., Molecular mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell Biol 15 (2014), 178–196.
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 9
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • 9 Reya, T., Morrison, S.J., Clarke, M.F., Weissman, I.L., Stem cells, cancer, and cancer stem cells. Nature 414 (2001), 105–111.
    • (2001) Nature , vol.414 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 10
    • 84884558125 scopus 로고    scopus 로고
    • Unravelling cancer stem cell potential
    • 10 Beck, B., Blanpain, C., Unravelling cancer stem cell potential. Nat Rev Cancer 13 (2013), 727–738.
    • (2013) Nat Rev Cancer , vol.13 , pp. 727-738
    • Beck, B.1    Blanpain, C.2
  • 11
    • 84891818171 scopus 로고    scopus 로고
    • Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?
    • 11 Sourisseau, T., Hassan, K.A., Wistuba, I., et al. Lung cancer stem cell: fancy conceptual model of tumor biology or cornerstone of a forthcoming therapeutic breakthrough?. J Thorac Oncol 9 (2014), 7–17.
    • (2014) J Thorac Oncol , vol.9 , pp. 7-17
    • Sourisseau, T.1    Hassan, K.A.2    Wistuba, I.3
  • 12
    • 84874618728 scopus 로고    scopus 로고
    • Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
    • 12 Wang, P., Gao, Q., Suo, Z., et al. Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines. PLoS One, 8, 2013, e57020.
    • (2013) PLoS One , vol.8 , pp. e57020
    • Wang, P.1    Gao, Q.2    Suo, Z.3
  • 13
    • 34249876564 scopus 로고    scopus 로고
    • Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
    • 13 Masui, S., Nakatake, Y., Toyooka, Y., et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 9 (2007), 625–635.
    • (2007) Nat Cell Biol , vol.9 , pp. 625-635
    • Masui, S.1    Nakatake, Y.2    Toyooka, Y.3
  • 14
    • 33646051846 scopus 로고    scopus 로고
    • Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components
    • 14 Sanada, Y., Yoshida, K., Ohara, M., Oeda, M., Konishi, K., Tsutani, Y., Histopathologic evaluation of stepwise progression of pancreatic carcinoma with immunohistochemical analysis of gastric epithelial transcription factor SOX2: comparison of expression patterns between invasive components and cancerous or nonneoplastic intraductal components. Pancreas 32 (2006), 164–170.
    • (2006) Pancreas , vol.32 , pp. 164-170
    • Sanada, Y.1    Yoshida, K.2    Ohara, M.3    Oeda, M.4    Konishi, K.5    Tsutani, Y.6
  • 15
    • 84866849548 scopus 로고    scopus 로고
    • Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer
    • 15 Rudin, C.M., Durinck, S., Stawiski, E.W., et al. Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer. Nat Genet 44 (2012), 1111–1116.
    • (2012) Nat Genet , vol.44 , pp. 1111-1116
    • Rudin, C.M.1    Durinck, S.2    Stawiski, E.W.3
  • 16
    • 77949360656 scopus 로고    scopus 로고
    • Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung
    • 16 Yuan, P., Kadara, H., Behrens, C., et al. Sex determining region Y-box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. PLoS One, 5, 2010, e9112.
    • (2010) PLoS One , vol.5 , pp. e9112
    • Yuan, P.1    Kadara, H.2    Behrens, C.3
  • 17
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • 17 Thiery, J.P., Acloque, H., Huang, R.Y., Nieto, M.A., Epithelial-mesenchymal transitions in development and disease. Cell 139 (2009), 871–890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 18
    • 84940263337 scopus 로고    scopus 로고
    • Overexpression of c-met increases the tumor invasion of human prostate LNCaP cancer cells and
    • 18 Han, Y., Luo, Y., Zhao, J., Li, M., Jiang, Y., Overexpression of c-met increases the tumor invasion of human prostate LNCaP cancer cells and. Oncol Lett 8 (2014), 1618–1624.
    • (2014) Oncol Lett , vol.8 , pp. 1618-1624
    • Han, Y.1    Luo, Y.2    Zhao, J.3    Li, M.4    Jiang, Y.5
  • 19
    • 84994610181 scopus 로고    scopus 로고
    • Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer
    • 19 Sylvester, P., Targeting met mediated epithelial-mesenchymal transition in the treatment of breast cancer. Clin Transl Med, 3, 2014, 30.
    • (2014) Clin Transl Med , vol.3 , pp. 30
    • Sylvester, P.1
  • 20
    • 84866652772 scopus 로고    scopus 로고
    • Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis
    • 20 Sato, M., Shames, D.S., Hasegawa, Y., Emerging evidence of epithelial-to-mesenchymal transition in lung carcinogenesis. Respirology 17 (2012), 1048–1059.
    • (2012) Respirology , vol.17 , pp. 1048-1059
    • Sato, M.1    Shames, D.S.2    Hasegawa, Y.3
  • 21
    • 82355185942 scopus 로고    scopus 로고
    • Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways
    • 21 Ogunwobi, O.O., Liu, C., Hepatocyte growth factor upregulation promotes carcinogenesis and epithelial-mesenchymal transition in hepatocellular carcinoma via Akt and COX-2 pathways. Clin Exp Metastasis 28 (2011), 721–731.
    • (2011) Clin Exp Metastasis , vol.28 , pp. 721-731
    • Ogunwobi, O.O.1    Liu, C.2
  • 22
    • 84896720813 scopus 로고    scopus 로고
    • Targeting epithelial-to-mesenchymal transition with met inhibitors reverts chemoresistance in small cell lung cancer
    • 22 Canadas, I., Rojo, F., Taus, A., et al. Targeting epithelial-to-mesenchymal transition with met inhibitors reverts chemoresistance in small cell lung cancer. Clin Cancer Res 20 (2014), 938–950.
    • (2014) Clin Cancer Res , vol.20 , pp. 938-950
    • Canadas, I.1    Rojo, F.2    Taus, A.3
  • 23
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • 23 Engelman, J.A., Zejnullahu, K., Mitsudomi, T., et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316 (2007), 1039–1043.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 24
    • 84868106386 scopus 로고    scopus 로고
    • Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor
    • 24 Hiltermann, T.J.N., Pore, M.M., van den Berg, A., et al. Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor. Ann Oncol 23 (2012), 2937–2942.
    • (2012) Ann Oncol , vol.23 , pp. 2937-2942
    • Hiltermann, T.J.N.1    Pore, M.M.2    van den Berg, A.3
  • 25
    • 79952755005 scopus 로고    scopus 로고
    • Circulating tumor cells as a window on metastasis biology in lung cancer
    • 25 Hou, J.M., Krebs, M., Ward, T., et al. Circulating tumor cells as a window on metastasis biology in lung cancer. Am J Pathol 178 (2011), 989–996.
    • (2011) Am J Pathol , vol.178 , pp. 989-996
    • Hou, J.M.1    Krebs, M.2    Ward, T.3
  • 26
    • 84907342688 scopus 로고    scopus 로고
    • Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
    • 26 Aceto, N., Bardia, A., Miyamoto, D.T., et al. Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell 158 (2014), 1110–1122.
    • (2014) Cell , vol.158 , pp. 1110-1122
    • Aceto, N.1    Bardia, A.2    Miyamoto, D.T.3
  • 27
    • 85027905477 scopus 로고    scopus 로고
    • Molecular characteristics of circulating tumour cells and circulating tumour microemboli in patients with lung cancer (abstract)
    • 27 Hou, J., Krebs, M., Ward, T., et al. Molecular characteristics of circulating tumour cells and circulating tumour microemboli in patients with lung cancer (abstract). J Thorac Oncol, 6, 2011, S670.
    • (2011) J Thorac Oncol , vol.6 , pp. S670
    • Hou, J.1    Krebs, M.2    Ward, T.3
  • 28
    • 84856862054 scopus 로고    scopus 로고
    • Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer
    • 28 Hou, J.M., Krebs, M.G., Lancashire, L., et al. Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. J Clin Oncol 30 (2012), 525–532.
    • (2012) J Clin Oncol , vol.30 , pp. 525-532
    • Hou, J.M.1    Krebs, M.G.2    Lancashire, L.3
  • 29
    • 84888785481 scopus 로고    scopus 로고
    • Elevated expression of SOX2 and FGFR1 in correlation with poor prognosis in patients with small cell lung cancer
    • 29 Yang, F., Gao, Y., Geng, J., et al. Elevated expression of SOX2 and FGFR1 in correlation with poor prognosis in patients with small cell lung cancer. Int J Clin Exp Pathol 6 (2013), 2846–2854.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 2846-2854
    • Yang, F.1    Gao, Y.2    Geng, J.3
  • 30
    • 77956534259 scopus 로고    scopus 로고
    • Autoimmunity to SOX2, clinical phenotype and survival in patients with small-cell lung cancer
    • 30 Maddison, P., Thorpe, A., Silcocks, P., Robertson, J.F., Chapman, C.J., Autoimmunity to SOX2, clinical phenotype and survival in patients with small-cell lung cancer. Lung Cancer 70 (2010), 335–339.
    • (2010) Lung Cancer , vol.70 , pp. 335-339
    • Maddison, P.1    Thorpe, A.2    Silcocks, P.3    Robertson, J.F.4    Chapman, C.J.5
  • 31
    • 0029941373 scopus 로고    scopus 로고
    • Bcl-2, p53, CD44, and CD44v6 isoform expression in neuroendocrine tumors of the lung
    • 31 Coppola, D., Clarke, M., Landreneau, R., Weyant, R.J., Cooper, D., Yousem, S.A., Bcl-2, p53, CD44, and CD44v6 isoform expression in neuroendocrine tumors of the lung. Mod Pathol 9 (1996), 484–490.
    • (1996) Mod Pathol , vol.9 , pp. 484-490
    • Coppola, D.1    Clarke, M.2    Landreneau, R.3    Weyant, R.J.4    Cooper, D.5    Yousem, S.A.6
  • 32
    • 84896517688 scopus 로고    scopus 로고
    • CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist
    • 32 Sarvi, S., Mackinnon, A.C., Avlonitis, N., et al. CD133+ cancer stem-like cells in small cell lung cancer are highly tumorigenic and chemoresistant but sensitive to a novel neuropeptide antagonist. Cancer Res 74 (2014), 1554–1565.
    • (2014) Cancer Res , vol.74 , pp. 1554-1565
    • Sarvi, S.1    Mackinnon, A.C.2    Avlonitis, N.3
  • 33
    • 84948429460 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
    • 33 Fischer, K.R., Durrans, A., Lee, S., et al. Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature 527 (2015), 472–476.
    • (2015) Nature , vol.527 , pp. 472-476
    • Fischer, K.R.1    Durrans, A.2    Lee, S.3
  • 34
    • 83555176312 scopus 로고    scopus 로고
    • Prognostic role of integrin beta1, E-cadherin, and rac1 expression in small cell lung cancer
    • 34 Chang, M.H., Lee, K., Lee, K.Y., Kim, Y.S., Kim, Y.K., Kang, J.H., Prognostic role of integrin beta1, E-cadherin, and rac1 expression in small cell lung cancer. APMIS 120 (2012), 28–38.
    • (2012) APMIS , vol.120 , pp. 28-38
    • Chang, M.H.1    Lee, K.2    Lee, K.Y.3    Kim, Y.S.4    Kim, Y.K.5    Kang, J.H.6
  • 35
    • 80052490815 scopus 로고    scopus 로고
    • MET phosphorylation predicts poor outcome in small cell lung carcinoma and its inhibition blocks HGF-induced effects in MET mutant cell lines
    • 35 Arriola, E., Canadas, I., Arumi-Uria, M., et al. MET phosphorylation predicts poor outcome in small cell lung carcinoma and its inhibition blocks HGF-induced effects in MET mutant cell lines. Br J Cancer 105 (2011), 814–823.
    • (2011) Br J Cancer , vol.105 , pp. 814-823
    • Arriola, E.1    Canadas, I.2    Arumi-Uria, M.3
  • 36
    • 84877063307 scopus 로고    scopus 로고
    • Neuroendocrine and epithelial phenotypes in small-cell lung cancer: implications for metastasis and survival in patients
    • 36 Stovold, R., Meredith, S.L., Bryant, J.L., et al. Neuroendocrine and epithelial phenotypes in small-cell lung cancer: implications for metastasis and survival in patients. Br J Cancer 108 (2013), 1704–1711.
    • (2013) Br J Cancer , vol.108 , pp. 1704-1711
    • Stovold, R.1    Meredith, S.L.2    Bryant, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.