Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions

Molecular Imaging and Biology

Volumn 19, Issue 1, 2017, Pages 41-48

  de Souza, Ana Luiza Ribeiro ^a,b   Marra, Kayla ^a   Gunn, Jason ^a   Samkoe, Kimberley S ^a,c   Hoopes, P Jack ^a,c   Feldwisch, Joachim ^d   Paulsen, Keith D ^a,c   Pogue, Brian W ^a,c  

^a DARTMOUTH COLLEGE   (United States)

^b MINISTRY OF EDUCATION OF BRAZIL   (Brazil)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d Affibody AB   (Sweden)

Author keywords

Anti EGFR affibody molecule; fluorescence guided surgery; Glioma; Pre GMP ABY 029

Indexed keywords

ABY 029; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; GADOLINIUM PENTETATE MEGLUMINE; UNCLASSIFIED DRUG; HYBRID PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG MICRODOSE; FLUORESCENCE IMAGING; GLIOMA; GLIOMA CELL LINE; HUMAN; HUMAN CELL; IN VIVO STUDY; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PLASMA CLEARANCE; PRIORITY JOURNAL; RAT; TUMOR GROWTH; TUMOR VOLUME; ANIMAL; BRAIN TUMOR; FEMALE; FLUORESCENCE; IMAGE PROCESSING; METABOLISM; NUDE RAT; PATHOLOGY; SIGNAL PROCESSING; STAINING; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; FLUORESCENCE; GLIOMA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; RATS, NUDE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL PROCESSING, COMPUTER-ASSISTED; STAINING AND LABELING;

EID: 84977124877     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-016-0980-7     Document Type: Article

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