메뉴 건너뛰기




Volumn 90, Issue 10, 2016, Pages 4876-4888

Investigating the influence of ribavirin on human respiratory syncytial virus rna synthesis by using a high-resolution transcriptome sequencing approach

Author keywords

[No Author keywords available]

Indexed keywords

RIBAVIRIN; RNA POLYMERASE; TRANSCRIPTOME; VIRUS RNA; ANTIVIRUS AGENT; BETA INTERFERON;

EID: 84977098569     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02349-15     Document Type: Article
Times cited : (34)

References (52)
  • 1
    • 39749139538 scopus 로고    scopus 로고
    • Viral and host factors in human respiratory syncytial virus pathogenesis
    • Collins PL, Graham BS. 2008. Viral and host factors in human respiratory syncytial virus pathogenesis. J Virol 82:2040-2055. http://dx.doi.org/10 .1128/JVI.01625-07.
    • (2008) J Virol , vol.82 , pp. 2040-2055
    • Collins, P.L.1    Graham, B.S.2
  • 2
    • 71949099031 scopus 로고    scopus 로고
    • From the American Academy of Pediatrics: policy statements-modified recommendations for use of palivizumab for prevention of respiratory syncytial virus infections
    • Committee on Infectious Diseases. 2009. From the American Academy of Pediatrics: policy statements-modified recommendations for use of palivizumab for prevention of respiratory syncytial virus infections. Pediatrics 124:1694-1701. http://dx.doi.org/10.1542/peds.2009-2345.
    • (2009) Pediatrics , vol.124 , pp. 1694-1701
  • 3
    • 17644392071 scopus 로고    scopus 로고
    • Respiratory syncytial virus infection in elderly and high-risk adults
    • Falsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE. 2005. Respiratory syncytial virus infection in elderly and high-risk adults. NEngl J Med 352:1749-1759. http://dx.doi.org/10.1056/NEJMoa043951.
    • (2005) NEngl J Med , vol.352 , pp. 1749-1759
    • Falsey, A.R.1    Hennessey, P.A.2    Formica, M.A.3    Cox, C.4    Walsh, E.E.5
  • 4
    • 84862856767 scopus 로고    scopus 로고
    • Pathogenesis of respiratory syncytial virus
    • Van Drunen Littel-Van Den Hurk S, Watkiss ER. 2012. Pathogenesis of respiratory syncytial virus. Curr Opin Virol 2:300-305. http://dx.doi.org /10.1016/j.coviro.2012.01.008.
    • (2012) Curr Opin Virol , vol.2 , pp. 300-305
    • Van Drunen Littel-Van Den Hurk, S.1    Watkiss, E.R.2
  • 5
    • 34548161084 scopus 로고    scopus 로고
    • The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings
    • MacLellan K, Loney C, Yeo R, Bhella D. 2007. The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings. J Virol 81:9519-9524. http://dx.doi.org/10.1128/JVI.00526-07.
    • (2007) J Virol , vol.81 , pp. 9519-9524
    • MacLellan, K.1    Loney, C.2    Yeo, R.3    Bhella, D.4
  • 6
    • 81555228664 scopus 로고    scopus 로고
    • Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years
    • Collins PL, Melero JA. 2011. Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years. Virus Res 162:80-99. http://dx.doi.org/10.1016/j.virusres.2011.09.020.
    • (2011) Virus Res , vol.162 , pp. 80-99
    • Collins, P.L.1    Melero, J.A.2
  • 7
    • 84892701276 scopus 로고    scopus 로고
    • Respiratory syncytial virus:virology, reverse genetics, and pathogenesis of disease
    • Collins PL, Fearns R, Graham BS. 2013. Respiratory syncytial virus:virology, reverse genetics, and pathogenesis of disease. Curr Top Microbiol Immunol 372:3-38. http://dx.doi.org/10.1007/978-3-642-38919-1_1.
    • (2013) Curr Top Microbiol Immunol , vol.372 , pp. 3-38
    • Collins, P.L.1    Fearns, R.2    Graham, B.S.3
  • 9
    • 0028092019 scopus 로고
    • Requirement of casein kinase II-mediated phosphorylation for the transcriptional activity of human respiratory syncytial viral phosphoprotein P: transdominant negative phenotype of phosphorylation- defective P mutants
    • Mazumder B, Barik S. 1994. Requirement of casein kinase II-mediated phosphorylation for the transcriptional activity of human respiratory syncytial viral phosphoprotein P: transdominant negative phenotype of phosphorylation- defective P mutants. Virology 205:104-111. http://dx.doi .org/10.1006/viro.1994.1624.
    • (1994) Virology , vol.205 , pp. 104-111
    • Mazumder, B.1    Barik, S.2
  • 10
    • 84868120541 scopus 로고    scopus 로고
    • The respiratory syncytial virus polymerase has multiple RNA synthesis activities at the promoter
    • Noton SL, Deflube LR, Tremaglio CZ, Fearns R. 2012. The respiratory syncytial virus polymerase has multiple RNA synthesis activities at the promoter. PLoS Pathog 8:e1002980. http://dx.doi.org/10.1371/journal .ppat.1002980.
    • (2012) PLoS Pathog , vol.8 , pp. e1002980
    • Noton, S.L.1    Deflube, L.R.2    Tremaglio, C.Z.3    Fearns, R.4
  • 11
    • 0033030058 scopus 로고    scopus 로고
    • Role of the M2-1 transcription antitermination protein of respiratory syncytial virus in sequential transcription
    • Fearns R, Collins PL. 1999. Role of the M2-1 transcription antitermination protein of respiratory syncytial virus in sequential transcription. J Virol 73:5852-5864.
    • (1999) J Virol , vol.73 , pp. 5852-5864
    • Fearns, R.1    Collins, P.L.2
  • 12
    • 0030028730 scopus 로고    scopus 로고
    • Transcription elongation factor of respiratory syncytial virus, a nonsegmented negativestrand RNA virus
    • Collins PL, Hill MG, Cristina J, Grosfeld H. 1996. Transcription elongation factor of respiratory syncytial virus, a nonsegmented negativestrand RNA virus. Proc Natl Acad Sci U S A 93:81-85. http://dx.doi.org /10.1073/pnas.93.1.81.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 81-85
    • Collins, P.L.1    Hill, M.G.2    Cristina, J.3    Grosfeld, H.4
  • 13
    • 84865097975 scopus 로고    scopus 로고
    • Characterization of a viral phosphoprotein binding site on the surface of the respiratory syncytial nucleoprotein
    • Galloux M, Tarus B, Blazevic I, Fix J, Duquerroy S, Eleouet JF. 2012. Characterization of a viral phosphoprotein binding site on the surface of the respiratory syncytial nucleoprotein. J Virol 86:8375-8387. http://dx .doi.org/10.1128/JVI.00058-12.
    • (2012) J Virol , vol.86 , pp. 8375-8387
    • Galloux, M.1    Tarus, B.2    Blazevic, I.3    Fix, J.4    Duquerroy, S.5    Eleouet, J.F.6
  • 14
    • 84937712896 scopus 로고    scopus 로고
    • Initiation and regulation of paramyxovirus transcription and replication
    • Noton SL, Fearns R. 2015. Initiation and regulation of paramyxovirus transcription and replication. Virology 479-480:545-554. http://dx.doi .org/10.1016/j.virol.2015.01.014.
    • (2015) Virology , vol.479-480 , pp. 545-554
    • Noton, S.L.1    Fearns, R.2
  • 15
    • 0022504445 scopus 로고
    • Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order
    • Collins PL, Dickens LE, Buckler-White A, Olmsted RA, Spriggs MK, Camargo E, Coelingh KV. 1986. Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order. Proc Natl Acad Sci U S A 83:4594-4598. http://dx.doi.org/10.1073/pnas.83.13.4594.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 4594-4598
    • Collins, P.L.1    Dickens, L.E.2    Buckler-White, A.3    Olmsted, R.A.4    Spriggs, M.K.5    Camargo, E.6    Coelingh, K.V.7
  • 16
    • 0029665573 scopus 로고    scopus 로고
    • Effects of mutations in the gene-start and gene-end sequence motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus
    • Kuo L, Grosfeld H, Cristina J, Hill MG, Collins PL. 1996. Effects of mutations in the gene-start and gene-end sequence motifs on transcription of monocistronic and dicistronic minigenomes of respiratory syncytial virus. J Virol 70:6892-6901.
    • (1996) J Virol , vol.70 , pp. 6892-6901
    • Kuo, L.1    Grosfeld, H.2    Cristina, J.3    Hill, M.G.4    Collins, P.L.5
  • 17
    • 0021739917 scopus 로고
    • Transcriptional mapping of human respiratory syncytial virus
    • Dickens LE, Collins PL, Wertz GW. 1984. Transcriptional mapping of human respiratory syncytial virus. J Virol 52:364-369.
    • (1984) J Virol , vol.52 , pp. 364-369
    • Dickens, L.E.1    Collins, P.L.2    Wertz, G.W.3
  • 18
    • 84874673020 scopus 로고    scopus 로고
    • Respiratory syncytial virus polymerase can initiate transcription from position 3 of the leader promoter
    • Tremaglio CZ, Noton SL, Deflube LR, Fearns R. 2013. Respiratory syncytial virus polymerase can initiate transcription from position 3 of the leader promoter. J Virol 87:3196-3207. http://dx.doi.org/10.1128/JVI .02862-12.
    • (2013) J Virol , vol.87 , pp. 3196-3207
    • Tremaglio, C.Z.1    Noton, S.L.2    Deflube, L.R.3    Fearns, R.4
  • 19
    • 0026705915 scopus 로고
    • Transcription of human respiratory syncytial virus genome RNA in vitro: requirement of cellular factor(s)
    • Barik S. 1992. Transcription of human respiratory syncytial virus genome RNA in vitro: requirement of cellular factor(s). J Virol 66:6813-6818.
    • (1992) J Virol , vol.66 , pp. 6813-6818
    • Barik, S.1
  • 20
    • 84892740572 scopus 로고    scopus 로고
    • Respiratory syncytial virus disease: prevention and treatment
    • Chu HY, Englund JA. 2013. Respiratory syncytial virus disease: prevention and treatment. Curr Top Microbiol Immunol 372:235-258. http://dx .doi.org/10.1007/978-3-642-38919-1_12.
    • (2013) Curr Top Microbiol Immunol , vol.372 , pp. 235-258
    • Chu, H.Y.1    Englund, J.A.2
  • 21
    • 84890068181 scopus 로고    scopus 로고
    • Respiratory syncytial virus lower respiratory disease in hematopoietic cell transplant recipients: viral RNA detection in blood, antiviral treatment, and clinical outcomes
    • Waghmare A, Campbell AP, Xie H, Seo S, Kuypers J, Leisenring W, Jerome KR, Englund JA, Boeckh M. 2013. Respiratory syncytial virus lower respiratory disease in hematopoietic cell transplant recipients: viral RNA detection in blood, antiviral treatment, and clinical outcomes. Clin Infect Dis 57:1731-1741. http://dx.doi.org/10.1093/cid/cit639.
    • (2013) Clin Infect Dis , vol.57 , pp. 1731-1741
    • Waghmare, A.1    Campbell, A.P.2    Xie, H.3    Seo, S.4    Kuypers, J.5    Leisenring, W.6    Jerome, K.R.7    Englund, J.A.8    Boeckh, M.9
  • 24
    • 77954414717 scopus 로고    scopus 로고
    • Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis
    • Soares-Weiser K, Thomas S, Thomson G, Garner P. 2010. Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis. BMC Infect Dis 10:207. http://dx.doi.org/10.1186/1471-2334-10-207.
    • (2010) BMC Infect Dis , vol.10 , pp. 207
    • Soares-Weiser, K.1    Thomas, S.2    Thomson, G.3    Garner, P.4
  • 25
    • 2442744266 scopus 로고
    • ADenosine kinase initiates the major route of ribavirin activation in a cultured human cell line
    • Willis RC, Carson DA, Seegmiller JE. 1978. ADenosine kinase initiates the major route of ribavirin activation in a cultured human cell line. Proc Natl Acad Sci U S A 75:3042-3044. http://dx.doi.org/10.1073/pnas.75.7 .3042.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 3042-3044
    • Willis, R.C.1    Carson, D.A.2    Seegmiller, J.E.3
  • 26
    • 0017879637 scopus 로고
    • Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5=-triphosphates in human blood and L5178Y cells
    • Zimmerman TP, Deeprose RD. 1978. Metabolism of 5-amino-1-beta-D-ribofuranosylimidazole-4-carboxamide and related five-membered heterocycles to 5=-triphosphates in human blood and L5178Y cells. Biochem Pharmacol 27:709-716. http://dx.doi.org/10.1016/0006-2952(78)90508-7.
    • (1978) Biochem Pharmacol , vol.27 , pp. 709-716
    • Zimmerman, T.P.1    Deeprose, R.D.2
  • 27
    • 33646560284 scopus 로고    scopus 로고
    • The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus
    • Dixit NM, Perelson AS. 2006. The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus. Cell Mol Life Sci 63:832-842. http://dx.doi.org/10.1007/s00018-005-5455-y.
    • (2006) Cell Mol Life Sci , vol.63 , pp. 832-842
    • Dixit, N.M.1    Perelson, A.S.2
  • 28
    • 31144445870 scopus 로고    scopus 로고
    • Mechanisms of action of ribavirin against distinct viruses
    • Graci JD, Cameron CE. 2006. Mechanisms of action of ribavirin against distinct viruses. Rev Med Virol 16:37-48. http://dx.doi.org/10.1002/rmv .483.
    • (2006) Rev Med Virol , vol.16 , pp. 37-48
    • Graci, J.D.1    Cameron, C.E.2
  • 29
    • 82955163230 scopus 로고    scopus 로고
    • Ribavirin for the treatment of chronic hepatitis C virus infection: a review of the proposed mechanisms of action
    • Paeshuyse J, Dallmeier K, Neyts J. 2011. Ribavirin for the treatment of chronic hepatitis C virus infection: a review of the proposed mechanisms of action. Curr Opin Virol 1:590-598. http://dx.doi.org/10.1016/j.coviro .2011.10.030.
    • (2011) Curr Opin Virol , vol.1 , pp. 590-598
    • Paeshuyse, J.1    Dallmeier, K.2    Neyts, J.3
  • 30
    • 0035208293 scopus 로고    scopus 로고
    • The mechanism of action of ribavirin:lethal mutagenesis of RNA virus genomes mediated by the viral RNAdepenDent RNA polymerase
    • Cameron CE, Castro C. 2001. The mechanism of action of ribavirin:lethal mutagenesis of RNA virus genomes mediated by the viral RNAdepenDent RNA polymerase. Curr Opin Infect Dis 14:757-764.
    • (2001) Curr Opin Infect Dis , vol.14 , pp. 757-764
    • Cameron, C.E.1    Castro, C.2
  • 31
    • 11844292013 scopus 로고    scopus 로고
    • Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications
    • Vignuzzi M, Stone JK, Andino R. 2005. Ribavirin and lethal mutagenesis of poliovirus: molecular mechanisms, resistance and biological implications. Virus Res 107:173-181. http://dx.doi.org/10.1016/j.virusres.2004 .11.007.
    • (2005) Virus Res , vol.107 , pp. 173-181
    • Vignuzzi, M.1    Stone, J.K.2    Andino, R.3
  • 32
    • 0042318456 scopus 로고    scopus 로고
    • Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase
    • Vo NV, Young KC, Lai MM. 2003. Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase. Biochemistry 42:10462-10471. http://dx.doi.org/10.1021/bi0344681.
    • (2003) Biochemistry , vol.42 , pp. 10462-10471
    • Vo, N.V.1    Young, K.C.2    Lai, M.M.3
  • 33
    • 0035811016 scopus 로고    scopus 로고
    • RNA virus error catastrophe:direct molecular test by using ribavirin
    • Crotty S, Cameron CE, Andino R. 2001. RNA virus error catastrophe:direct molecular test by using ribavirin. Proc Natl Acad SciUS A 98:6895-6900. http://dx.doi.org/10.1073/pnas.111085598.
    • (2001) Proc Natl Acad SciUS A , vol.98 , pp. 6895-6900
    • Crotty, S.1    Cameron, C.E.2    Andino, R.3
  • 34
    • 0022632904 scopus 로고
    • Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells
    • Smee DF, Matthews TR. 1986. Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells. Antimicrob Agents Chemother 30:117-121. http://dx.doi.org/10.1128/AAC.30.1.117.
    • (1986) Antimicrob Agents Chemother , vol.30 , pp. 117-121
    • Smee, D.F.1    Matthews, T.R.2
  • 35
    • 13744258758 scopus 로고    scopus 로고
    • The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
    • Leyssen P, Balzarini J, De Clercq E, Neyts J. 2005. The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase. J Virol 79:1943-1947. http://dx.doi.org/10.1128/JVI.79.3.1943-1947.2005.
    • (2005) J Virol , vol.79 , pp. 1943-1947
    • Leyssen, P.1    Balzarini, J.2    De Clercq, E.3    Neyts, J.4
  • 40
    • 0037791758 scopus 로고    scopus 로고
    • IDentification of a single amino acid change in the human respiratory syncytial virus L protein that affects transcriptional termination
    • Cartee TL, Megaw AG, Oomens AGP, Wertz GW. 2003. IDentification of a single amino acid change in the human respiratory syncytial virus L protein that affects transcriptional termination. J Virol 77:7352-7360. http://dx.doi.org/10.1128/JVI.77.13.7352-7360.2003.
    • (2003) J Virol , vol.77 , pp. 7352-7360
    • Cartee, T.L.1    Megaw, A.G.2    Oomens, A.G.P.3    Wertz, G.W.4
  • 43
    • 84874543845 scopus 로고    scopus 로고
    • Hsp90 inhibitors exhibit resistance- free antiviral activity against respiratory syncytial virus
    • Geller R, Andino R, Frydman J. 2013. Hsp90 inhibitors exhibit resistance- free antiviral activity against respiratory syncytial virus. PLoS One 8:e56762. http://dx.doi.org/10.1371/journal.pone.0056762.
    • (2013) PLoS One , vol.8 , pp. e56762
    • Geller, R.1    Andino, R.2    Frydman, J.3
  • 45
    • 34247191488 scopus 로고    scopus 로고
    • Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses
    • Connor JH, McKenzie MO, Parks GD, Lyles DS. 2007. Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses. Virology 362:109-119. http://dx.doi.org/10 .1016/j.virol.2006.12.026.
    • (2007) Virology , vol.362 , pp. 109-119
    • Connor, J.H.1    McKenzie, M.O.2    Parks, G.D.3    Lyles, D.S.4
  • 46
    • 9244238208 scopus 로고    scopus 로고
    • Viral error catastrophe by mutagenic nucleosides
    • Anderson JP, Daifuku R, Loeb LA. 2004. Viral error catastrophe by mutagenic nucleosides. Annu Rev Microbiol 58:183-205. http://dx.doi .org/10.1146/annurev.micro.58.030603.123649.
    • (2004) Annu Rev Microbiol , vol.58 , pp. 183-205
    • Anderson, J.P.1    Daifuku, R.2    Loeb, L.A.3
  • 47
    • 0027221640 scopus 로고
    • Rates of spontaneous mutation among RNA viruses
    • Drake JW. 1993. Rates of spontaneous mutation among RNA viruses. Proc Natl Acad Sci U S A 90:4171-4175. http://dx.doi.org/10.1073/pnas .90.9.4171.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 4171-4175
    • Drake, J.W.1
  • 48
    • 0036849786 scopus 로고    scopus 로고
    • Implications of high RNA virus mutation rates:lethal mutagenesis and the antiviral drug ribavirin
    • Crotty S, Andino R. 2002. Implications of high RNA virus mutation rates:lethal mutagenesis and the antiviral drug ribavirin. Microbes Infect 4:1301-1307. http://dx.doi.org/10.1016/S1286-4579(02)00008-4.
    • (2002) Microbes Infect , vol.4 , pp. 1301-1307
    • Crotty, S.1    Andino, R.2
  • 49
    • 0036182633 scopus 로고    scopus 로고
    • Ribavirin's antiviral mechanism of action: lethal mutagenesis?
    • Crotty S, Cameron C, Andino R. 2002. Ribavirin's antiviral mechanism of action: lethal mutagenesis? J Mol Med (Berl) 80:86-95. http://dx.doi .org/10.1007/s00109-001-0308-0.
    • (2002) J Mol Med (Berl) , vol.80 , pp. 86-95
    • Crotty, S.1    Cameron, C.2    Andino, R.3
  • 50
    • 79952069367 scopus 로고    scopus 로고
    • ADenosine deaminases acting on RNA (ADARs) are both antiviral and proviral
    • Samuel CE. 2011. ADenosine deaminases acting on RNA (ADARs) are both antiviral and proviral. Virology 411:180-193. http://dx.doi.org/10 .1016/j.virol.2010.12.004.
    • (2011) Virology , vol.411 , pp. 180-193
    • Samuel, C.E.1
  • 52
    • 0036275298 scopus 로고    scopus 로고
    • A model for the generation of multiple A to G transitions in the human respiratory syncytial virus genome: predicted RNA secondary structures as substrates for aDenosine deaminases that act on RNA
    • Martinez I, Melero JA. 2002. A model for the generation of multiple A to G transitions in the human respiratory syncytial virus genome: predicted RNA secondary structures as substrates for aDenosine deaminases that act on RNA. J Gen Virol 83:1445-1455. http://dx.doi.org/10.1099/0022-1317-83-6-1445.
    • (2002) J Gen Virol , vol.83 , pp. 1445-1455
    • Martinez, I.1    Melero, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.