-
1
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell. 2011;144(5):646-674.
-
(2011)
Cell.
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309-314.
-
(1956)
Science.
, vol.123
, Issue.3191
, pp. 309-314
-
-
Warburg, O.1
-
3
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metabolism. 2008;7(1):11-20.
-
(2008)
Cell Metabolism.
, vol.7
, Issue.1
, pp. 11-20
-
-
DeBerardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
4
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar A, Poisson LM, Rajendiran TM, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009;457(7231):910-914.
-
(2009)
Nature.
, vol.457
, Issue.7231
, pp. 910-914
-
-
Sreekumar, A.1
Poisson, L.M.2
Rajendiran, T.M.3
-
5
-
-
84875496294
-
(R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible
-
Losman JA, Looper RE, Koivunen P, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013;339(6127):1621-1625.
-
(2013)
Science.
, vol.339
, Issue.6127
, pp. 1621-1625
-
-
Losman, J.A.1
Looper, R.E.2
Koivunen, P.3
-
6
-
-
77956674635
-
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
-
Vander Heiden MG, Locasale JW, Swanson KD, et al. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science. 2010;329(5998):1492-1499.
-
(2010)
Science.
, vol.329
, Issue.5998
, pp. 1492-1499
-
-
Vander Heiden, M.G.1
Locasale, J.W.2
Swanson, K.D.3
-
7
-
-
80051923932
-
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
-
Possemato R, Marks KM, Shaul YD, et al. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011;476(7360):346-350.
-
(2011)
Nature.
, vol.476
, Issue.7360
, pp. 346-350
-
-
Possemato, R.1
Marks, K.M.2
Shaul, Y.D.3
-
8
-
-
84920972493
-
Nitric oxide mediates metabolic coupling of omentum-derived adipose stroma to ovarian and endometrial cancer cells
-
Salimian Rizi B, Caneba C, Nowicka A, et al. Nitric oxide mediates metabolic coupling of omentum-derived adipose stroma to ovarian and endometrial cancer cells. Cancer Res. 2015;75(2):456-471.
-
(2015)
Cancer Res.
, vol.75
, Issue.2
, pp. 456-471
-
-
Salimian Rizi, B.1
Caneba, C.2
Nowicka, A.3
-
9
-
-
70350728803
-
MYC-induced cancer cell energy metabolism and therapeutic opportunities
-
Dang CV, Le A, Gao P. MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res. 2009;15(21):6479-6483.
-
(2009)
Clin Cancer Res.
, vol.15
, Issue.21
, pp. 6479-6483
-
-
Dang, C.V.1
Le, A.2
Gao, P.3
-
10
-
-
84875894714
-
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
-
Son J, Lyssiotis CA, Ying H, et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature. 2013;496(7443):101-105.
-
(2013)
Nature.
, vol.496
, Issue.7443
, pp. 101-105
-
-
Son, J.1
Lyssiotis, C.A.2
Ying, H.3
-
11
-
-
68849083050
-
Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems
-
Evans AM, DeHaven CD, Barrett T, Mitchell M, Milgram E. Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. Anal Chem. 2009;81(16):6656-6667.
-
(2009)
Anal Chem.
, vol.81
, Issue.16
, pp. 6656-6667
-
-
Evans, A.M.1
DeHaven, C.D.2
Barrett, T.3
Mitchell, M.4
Milgram, E.5
-
12
-
-
84864612118
-
Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients
-
Weiner J 3rd, Parida SK, Maertzdorf J, et al. Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients. PloS One. 2012;7(7):e40221.
-
(2012)
PloS One.
, vol.7
, Issue.7
, pp. e40221
-
-
Weiner, J.1
Parida, S.K.2
Maertzdorf, J.3
-
13
-
-
44949233606
-
Analysis of the adult human plasma metabolome
-
Lawton KA, Berger A, Mitchell M, et al. Analysis of the adult human plasma metabolome. Pharmacogenomics. 2008;9(4):383-397.
-
(2008)
Pharmacogenomics.
, vol.9
, Issue.4
, pp. 383-397
-
-
Lawton, K.A.1
Berger, A.2
Mitchell, M.3
-
14
-
-
78649702566
-
Organization of GC/MS and LC/MS metabolomics data into chemical libraries
-
Dehaven CD, Evans AM, Dai H, Lawton KA. Organization of GC/MS and LC/MS metabolomics data into chemical libraries. J Cheminform. 2010;2(1):9.
-
(2010)
J Cheminform.
, vol.2
, Issue.1
, pp. 9
-
-
Dehaven, C.D.1
Evans, A.M.2
Dai, H.3
Lawton, K.A.4
-
15
-
-
58049213696
-
Dicer, drosha, and outcomes in patients with ovarian cancer
-
Merritt WM, Lin YG, Han LY, et al. Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer. New Engl J Med. 2008;359(25):2641-2650.
-
(2008)
New Engl J Med.
, vol.359
, Issue.25
, pp. 2641-2650
-
-
Merritt, W.M.1
Lin, Y.G.2
Han, L.Y.3
-
16
-
-
33746851955
-
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma
-
Thaker PH, Han LY, Kamat AA, et al. Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med. 2006;12(8):939-944.
-
(2006)
Nat Med.
, vol.12
, Issue.8
, pp. 939-944
-
-
Thaker, P.H.1
Han, L.Y.2
Kamat, A.A.3
-
17
-
-
0024443170
-
Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites
-
Li L, Price JE, Fan D, Zhang RD, Bucana CD, Fidler IJ. Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites. J Natl Cancer Inst. 1989;81(18):1406-1412.
-
(1989)
J Natl Cancer Inst.
, vol.81
, Issue.18
, pp. 1406-1412
-
-
Li, L.1
Price, J.E.2
Fan, D.3
Zhang, R.D.4
Bucana, C.D.5
Fidler, I.J.6
-
18
-
-
77955541508
-
Regulation of tumor angiogenesis by EZH2
-
Lu C, Han HD, Mangala LS, et al. Regulation of tumor angiogenesis by EZH2. Cancer Cell. 2010;18(2):185-197.
-
(2010)
Cancer Cell.
, vol.18
, Issue.2
, pp. 185-197
-
-
Lu, C.1
Han, H.D.2
Mangala, L.S.3
-
19
-
-
33750581780
-
Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer
-
Landen CN Jr, Lu C, Han LY, et al. Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer. J Natl Cancer Inst. 2006;98(21):1558-1570.
-
(2006)
J Natl Cancer Inst.
, vol.98
, Issue.21
, pp. 1558-1570
-
-
Landen, C.N.1
Lu, C.2
Han, L.Y.3
-
20
-
-
40949126550
-
Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth
-
Merritt WM, Lin YG, Spannuth WA, et al. Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth. J Natl Cancer Inst. 2008;100(5):359-372.
-
(2008)
J Natl Cancer Inst.
, vol.100
, Issue.5
, pp. 359-372
-
-
Merritt, W.M.1
Lin, Y.G.2
Spannuth, W.A.3
-
21
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A. 2003;100(16):9440-9445.
-
(2003)
Proc Natl Acad Sci U S A.
, vol.100
, Issue.16
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
22
-
-
52649085237
-
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
-
Tothill RW, Tinker AV, George J, et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin Cancer Res. 2008;14(16):5198-5208.
-
(2008)
Clin Cancer Res.
, vol.14
, Issue.16
, pp. 5198-5208
-
-
Tothill, R.W.1
Tinker, A.V.2
George, J.3
-
23
-
-
73949140415
-
Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
-
Bogunovic D, O'Neill DW, Belitskaya-Levy I, et al. Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival. Proc Natl Acad Sci U S A. 2009;106(48):20429-20434.
-
(2009)
Proc Natl Acad Sci U S A.
, vol.106
, Issue.48
, pp. 20429-20434
-
-
Bogunovic, D.1
O'Neill, D.W.2
Belitskaya-Levy, I.3
-
24
-
-
77954234849
-
Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome
-
Jonsson G, Busch C, Knappskog S, et al. Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome. Clin Cancer Res. 2010;16(13):3356-3367.
-
(2010)
Clin Cancer Res.
, vol.16
, Issue.13
, pp. 3356-3367
-
-
Jonsson, G.1
Busch, C.2
Knappskog, S.3
-
25
-
-
70449647008
-
Proportional hazards tests and diagnostics based on weighted residuals
-
Grambsch PM, Therneau TM. Proportional Hazards Tests and Diagnostics Based on Weighted Residuals. Biometrika. 1994;81(3):515-526.
-
(1994)
Biometrika.
, vol.81
, Issue.3
, pp. 515-526
-
-
Grambsch, P.M.1
Therneau, T.M.2
-
26
-
-
84903764168
-
Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells
-
Caneba CA, Yang L, Baddour J, et al. Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells. Cell Death Dis. 2014;5:e1302.
-
(2014)
Cell Death Dis.
, vol.5
, pp. e1302
-
-
Caneba, C.A.1
Yang, L.2
Baddour, J.3
-
27
-
-
84901624185
-
Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer
-
Yang L, Moss T, Mangala LS, et al. Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer. Mol Syst Biol. 2014;10:728.
-
(2014)
Mol Syst Biol.
, vol.10
, pp. 728
-
-
Yang, L.1
Moss, T.2
Mangala, L.S.3
-
28
-
-
84862630475
-
NetWalker: A contextual network analysis tool for functional genomics
-
Komurov K, Dursun S, Erdin S, Ram PT. NetWalker: A contextual network analysis tool for functional genomics. BMC Genomics. 2012;13:282.
-
(2012)
BMC Genomics.
, vol.13
, pp. 282
-
-
Komurov, K.1
Dursun, S.2
Erdin, S.3
Ram, P.T.4
-
29
-
-
0000356642
-
Studies on the distribution of N-acetyl-L-aspartic acid in brain
-
Tallan HH. Studies on the distribution of N-acetyl-L-aspartic acid in brain. J Biol Chem. 1957;224(1):41-45.
-
(1957)
J Biol Chem.
, vol.224
, Issue.1
, pp. 41-45
-
-
Tallan, H.H.1
-
30
-
-
0000701624
-
Studies on the free amino acids and related compounds in the tissues of the cat
-
Tallan HH, Moore S, Stein WH. Studies on the free amino acids and related compounds in the tissues of the cat. J Biol Chem. 1954;211(2):927-939.
-
(1954)
J Biol Chem.
, vol.211
, Issue.2
, pp. 927-939
-
-
Tallan, H.H.1
Moore, S.2
Stein, W.H.3
-
31
-
-
77952240030
-
Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: Implications for specialized acetyl coenzyme A metabolism in the CNS
-
Ariyannur PS, Moffett JR, Manickam P, et al. Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS. Brain Res. 2010;1335:1-13.
-
(2010)
Brain Res.
, vol.1335
, pp. 1-13
-
-
Ariyannur, P.S.1
Moffett, J.R.2
Manickam, P.3
-
32
-
-
72449146905
-
Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia
-
Wiame E, Tyteca D, Pierrot N, et al. Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia. Biochem J. 2010;425(1):127-136.
-
(2010)
Biochem J.
, vol.425
, Issue.1
, pp. 127-136
-
-
Wiame, E.1
Tyteca, D.2
Pierrot, N.3
-
33
-
-
33847141978
-
N-Acetylaspartate in the CNS: From neurodiagnostics to neurobiology
-
Moffett JR, Ross B, Arun P, Madhavarao CN, Namboodiri AM. N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology. Prog Neurobiol. 2007;81(2):89-131.
-
(2007)
Prog Neurobiol.
, vol.81
, Issue.2
, pp. 89-131
-
-
Moffett, J.R.1
Ross, B.2
Arun, P.3
Madhavarao, C.N.4
Namboodiri, A.M.5
-
34
-
-
84864285263
-
Differences in metabolism of fiber tract alterations in gliomas: A combined fiber density mapping and magnetic resonance spectroscopic imaging study
-
Stadlbauer A, Hammen T, Buchfelder M, et al. Differences in metabolism of fiber tract alterations in gliomas: A combined fiber density mapping and magnetic resonance spectroscopic imaging study. Neurosurgery. 2012;71(2):454-463.
-
(2012)
Neurosurgery.
, vol.71
, Issue.2
, pp. 454-463
-
-
Stadlbauer, A.1
Hammen, T.2
Buchfelder, M.3
-
35
-
-
84877100892
-
Survival analysis in patients with newly diagnosed glioblastoma using pre-and postradiotherapy MR spectroscopic imaging
-
Li Y, Lupo JM, Parvataneni R, et al. Survival analysis in patients with newly diagnosed glioblastoma using pre-and postradiotherapy MR spectroscopic imaging. Neuro-oncology. 2013;15(5):607-617.
-
(2013)
Neuro-oncology.
, vol.15
, Issue.5
, pp. 607-617
-
-
Li, Y.1
Lupo, J.M.2
Parvataneni, R.3
-
36
-
-
84864581956
-
Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: Initial results
-
Yao X, Zeng M, Wang H, Fei S, Rao S, Ji Y. Metabolite detection of pancreatic carcinoma by in vivo proton MR spectroscopy at 3T: initial results. Radiol Med. 2012;117(5):780-788.
-
(2012)
Radiol Med.
, vol.117
, Issue.5
, pp. 780-788
-
-
Yao, X.1
Zeng, M.2
Wang, H.3
Fei, S.4
Rao, S.5
Ji, Y.6
-
37
-
-
79956289372
-
Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer
-
Fong MY, McDunn J, Kakar SS. Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. PloS One. 2011;6(5):e19963.
-
(2011)
PloS One.
, vol.6
, Issue.5
, pp. e19963
-
-
Fong, M.Y.1
McDunn, J.2
Kakar, S.S.3
-
38
-
-
79959197094
-
Metabolomic characterization of ovarian epithelial carcinomas by HRMAS-NMR spectroscopy
-
Ben Sellem D, Elbayed K, Neuville A, et al. Metabolomic Characterization of Ovarian Epithelial Carcinomas by HRMAS-NMR Spectroscopy. J Oncol. 2011;2011:174019.
-
(2011)
J Oncol.
, vol.2011
, pp. 174019
-
-
Ben Sellem, D.1
Elbayed, K.2
Neuville, A.3
-
39
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
Cancer Genome Atlas Research N. Integrated genomic analyses of ovarian carcinoma. Nature. 2011;474(7353):609-615.
-
(2011)
Nature.
, vol.474
, Issue.7353
, pp. 609-615
-
-
Cancer Genome Atlas Research N1
|