Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: A prospective, open-label, randomised, multicentre study

Critical Care

Volumn 20, Issue 1, 2016, Pages

  Conti, Giorgio ^a   Ranieri, Vito Marco ^b   Costa, Roberta ^a   Garratt, Chris ^c   Wighton, Andrew ^c   Spinazzola, Giorgia ^a   Urbino, Rosario ^d   Mascia, Luciana ^b   Ferrone, Giuliano ^a   Pohjanjousi, Pasi ^e   Ferreyra, Gabriela ^d   Antonelli, Massimo ^a  

^a FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Orion Pharma R and D   (United Kingdom)

^d UNIVERSITY OF TURIN   (Italy)

^e ORION CORPORATION   (Finland)

Author keywords

Dexmedetomidine; Mechanical ventilation; Patient ventilator synchrony; Propofol; Sedation

Indexed keywords

DEXMEDETOMIDINE; PROPOFOL; HYPNOTIC SEDATIVE AGENT;

ADULT; AGED; ARTICLE; BRADYCARDIA; BRONCHUS SECRETION; CLINICAL ARTICLE; CONTROLLED STUDY; COUGHING; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EXTUBATION; FEMALE; HUMAN; INTENSIVE CARE UNIT; ITALY; LENGTH OF STAY; MALE; MAN MACHINE INTERACTION; MECHANICAL VENTILATOR; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RICHMOND AGITATION SEDATION SCALE; SEDATION; SIDE EFFECT; SUDDEN CARDIAC DEATH; URINARY TRACT INFECTION; VENTILATOR WEANING; ANALYSIS OF VARIANCE; ARTIFICIAL VENTILATION; MIDDLE AGED; ORGANIZATION AND MANAGEMENT; PROCEDURES; STANDARDS; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; DEXMEDETOMIDINE; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INTENSIVE CARE UNITS; ITALY; MALE; MIDDLE AGED; PROPOFOL; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; VENTILATOR WEANING;

EID: 84976894788     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-016-1386-2     Document Type: Article

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