Updates on cardiovascular comorbidities associated with psoriatic diseases: epidemiology and mechanisms

Rheumatology International

Volumn 37, Issue 1, 2017, Pages 97-105

  Yim, Kaitlyn M ^a   Armstrong, April W ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cardiovascular comorbidities; Comorbidities; Inflammation; Mechanisms; Psoriasis

Indexed keywords

ADIPOCYTOKINE;

ANGIOGENESIS; BODY SURFACE; CARDIAC PATIENT; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; COMORBIDITY; DIABETIC PATIENT; DISEASE ASSOCIATION; DISEASE SEVERITY; DYSLIPIDEMIA; HEALTH PROGRAM; HUMAN; HYPERTENSION; INCIDENCE; INSULIN RESISTANCE; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; OXIDATIVE STRESS; PRACTICE GUIDELINE; PRIORITY JOURNAL; PSORIASIS; PSORIATIC ARTHRITIS; REVIEW; ARTHRITIS, PSORIATIC; CARDIOVASCULAR DISEASES; PREVALENCE;

ARTHRITIS, PSORIATIC; CARDIOVASCULAR DISEASES; COMORBIDITY; HUMANS; PREVALENCE; PSORIASIS;

EID: 84976642295     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-016-3487-2     Document Type: Review

References (66)

1. Rachakonda TD, Schupp CW, Armstrong AW (2014) Psoriasis prevalence among adults in the United States. J Am Acad Dermatol 70(3):512–516. doi:10.1016/j.jaad.2013.11.013
2. Parisi R, Symmons DP, Griffiths CE, Ashcroft DM (2013) Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol 133(2):377–385. doi:10.1038/jid.2012.339
3. Yeung H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, Shin DB, Attor R, Troxel AB, Gelfand JM (2013) Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol 149(10):1173–1179. doi:10.1001/jamadermatol.2013.5015
4. Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel AB (2009) The risk of stroke in patients with psoriasis. J Invest Dermatol 129(10):2411–2418. doi:10.1038/jid.2009.112
5. Gelfand JM, Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB (2006) Risk of myocardial infarction in patients with psoriasis. JAMA 296(14):1735–1741. doi:10.1001/jama.296.14.1735
6. Mehta NN, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM (2010) Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the general practice research database. Eur Heart J 31(8):1000–1006. doi:10.1093/eurheartj/ehp567
7. Armstrong EJ, Harskamp CT, Armstrong AW (2013) Psoriasis and major adverse cardiovascular events: a systematic review and meta-analysis of observational studies. J Am Heart Assoc 2(2):e000062. doi:10.1161/jaha.113.000062
8. Abuabara K, Azfar RS, Shin DB, Neimann AL, Troxel AB, Gelfand JM (2010) Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the UK. Br J Dermatol 163(3):586–592. doi:10.1111/j.1365-2133.2010.09941.x
9. Pariser DM, Bagel J, Gelfand JM, Korman NJ, Ritchlin CT, Strober BE, Van Voorhees AS, Young M, Rittenberg S, Lebwohl MG, Horn EJ (2007) National psoriasis foundation clinical consensus on disease severity. Arch Dermatol 143(2):239–242. doi:10.1001/archderm.143.2.239
10. Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM (2006) Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol 55(5):829–835. doi:10.1016/j.jaad.2006.08.040
11. Takeshita J, Wang S, Shin DB, Mehta NN, Kimmel SE, Margolis DJ, Troxel AB, Gelfand JM (2015) Effect of psoriasis severity on hypertension control: a population-based study in the United Kingdom. JAMA Dermatol 151(2):161–169. doi:10.1001/jamadermatol.2014.2094
12. Armstrong AW, Lin SW, Chambers CJ, Sockolov ME, Chin DL (2011) Psoriasis and hypertension severity: results from a case-control study. PLoS One 6(3):e18227. doi:10.1371/journal.pone.0018227
13. Khalid U, Hansen PR, Gislason GH, Lindhardsen J, Kristensen SL, Winther SA, Skov L, Torp-Pedersen C, Ahlehoff O (2013) Psoriasis and new-onset diabetes: a Danish nationwide cohort study. Diabetes Care 36(8):2402–2407. doi:10.2337/dc12-2330
14. Langan SM, Seminara NM, Shin DB, Troxel AB, Kimmel SE, Mehta NN, Margolis DJ, Gelfand JM (2012) Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom. J Invest Dermatol 132(3 Pt 1):556–562. doi:10.1038/jid.2011.365
15. Love TJ, Qureshi AA, Karlson EW, Gelfand JM, Choi HK (2011) Prevalence of the metabolic syndrome in psoriasis: results from the National Health and Nutrition Examination Survey, 2003–2006. Arch Dermatol 147(4):419–424. doi:10.1001/archdermatol.2010.370
16. Kimball AB, Szapary P, Mrowietz U, Reich K, Langley RG, You Y, Hsu MC, Yeilding N, Rader DJ, Mehta NN (2012) Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis. J Am Acad Dermatol 67(1):76–85. doi:10.1016/j.jaad.2011.06.035
17. Takahashi H, Takahashi I, Honma M, Ishida-Yamamoto A, Iizuka H (2010) Prevalence of metabolic syndrome in Japanese psoriasis patients. J Dermatol Sci 57(2):143–144. doi:10.1016/j.jdermsci.2009.11.002
18. Ma C, Harskamp CT, Armstrong EJ, Armstrong AW (2013) The association between psoriasis and dyslipidaemia: a systematic review. Br J Dermatol 168(3):486–495. doi:10.1111/bjd.12101
19. Chen YJ, Shen JL, Wu CY, Chang YT, Chen CM, Lee FY (2009) Elevated plasma osteopontin level is associated with occurrence of psoriasis and is an unfavorable cardiovascular risk factor in patients with psoriasis. J Am Acad Dermatol 60(2):225–230. doi:10.1016/j.jaad.2008.09.046
20. Chen YJ, Wu CY, Shen JL, Chu SY, Chen CK, Chang YT, Chen CM (2008) Psoriasis independently associated with hyperleptinemia contributing to metabolic syndrome. Arch Dermatol 144(12):1571–1575. doi:10.1001/archderm.144.12.1571
21. Cohen AD, Sherf M, Vidavsky L, Vardy DA, Shapiro J, Meyerovitch J (2008) Association between psoriasis and the metabolic syndrome. A cross-sectional study. Dermatology (Basel, Switzerland). doi:10.1159/000111512
22. Ma C, Schupp CW, Armstrong EJ, Armstrong AW (2014) Psoriasis and dyslipidemia: a population-based study analyzing the National Health and Nutrition Examination Survey (NHANES). J Eur Acad Dermatol Venereol JEADV 28(8):1109–1112. doi:10.1111/jdv.12232
23. Ahlehoff O, Gislason GH, Charlot M, Jorgensen CH, Lindhardsen J, Olesen JB, Abildstrom SZ, Skov L, Torp-Pedersen C, Hansen PR (2011) Psoriasis is associated with clinically significant cardiovascular risk: a Danish nationwide cohort study. J Intern Med 270(2):147–157. doi:10.1111/j.1365-2796.2010.02310.x
24. Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaci D, Kaufmann R, Vogl TJ, Boehncke WH (2007) Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol 156(2):271–276. doi:10.1111/j.1365-2133.2006.07562.x
25. Armstrong AW, Harskamp CT, Ledo L, Rogers JH, Armstrong EJ (2012) Coronary artery disease in patients with psoriasis referred for coronary angiography. Am J Cardiol 109(7):976–980. doi:10.1016/j.amjcard.2011.11.025
26. Ahlehoff O, Gislason GH, Lindhardsen J, Olesen JB, Charlot M, Skov L, Torp-Pedersen C, Hansen PR (2011) Prognosis following first-time myocardial infarction in patients with psoriasis: a Danish nationwide cohort study. J Intern Med 270(3):237–244. doi:10.1111/j.1365-2796.2011.02368.x
27. Mehta NN, Yu Y, Pinnelas R, Krishnamoorthy P, Shin DB, Troxel AB, Gelfand JM (2011) Attributable risk estimate of severe psoriasis on major cardiovascular events. Am J Med. doi:10.1016/j.amjmed.2011.03.028
28. Ogdie A, Yu Y, Haynes K, Love TJ, Maliha S, Jiang Y, Troxel AB, Hennessy S, Kimmel SE, Margolis DJ, Choi H, Mehta NN, Gelfand JM (2015) Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study. Ann Rheum Dis 74(2):326–332. doi:10.1136/annrheumdis-2014-205675
29. Parisi R, Rutter MK, Lunt M, Young HS, Symmons DP, Griffiths CE, Ashcroft DM (2015) Psoriasis and the risk of major cardiovascular events: cohort study using the clinical practice research datalink. J Invest Dermatol 135(9):2189–2197. doi:10.1038/jid.2015.87
30. Armstrong AW, Harskamp CT, Armstrong EJ (2012) The association between psoriasis and obesity: a systematic review and meta-analysis of observational studies. Nutr Diabetes 2:e54. doi:10.1038/nutd.2012.26
31. Armstrong AW, Harskamp CT, Armstrong EJ (2013) The association between psoriasis and hypertension: a systematic review and meta-analysis of observational studies. J Hypertens. doi:10.1097/HJH.0b013e32835bcce1
32. Armstrong AW, Harskamp CT, Armstrong EJ (2013) Psoriasis and the risk of diabetes mellitus: a systematic review and meta-analysis. JAMA Dermatol 149(1):84–91. doi:10.1001/2013.jamadermatol.406
33. Armstrong AW, Harskamp CT, Armstrong EJ (2013) Psoriasis and metabolic syndrome: a systematic review and meta-analysis of observational studies. J Am Acad Dermatol 68(4):654–662. doi:10.1016/j.jaad.2012.08.015
34. Samarasekera EJ, Neilson JM, Warren RB, Parnham J, Smith CH (2013) Incidence of cardiovascular disease in individuals with psoriasis: a systematic review and meta-analysis. J Invest Dermatol 133(10):2340–2346. doi:10.1038/jid.2013.149
35. Mease PJ, Gladman DD, Papp KA, Khraishi MM, Thaci D, Behrens F, Northington R, Fuiman J, Bananis E, Boggs R, Alvarez D (2013) Prevalence of rheumatologist-diagnosed psoriatic arthritis in patients with psoriasis in European/North American dermatology clinics. J Am Acad Dermatol 69(5):729–735. doi:10.1016/j.jaad.2013.07.023
36. Armstrong AW, Schupp C, Bebo B (2012) Psoriasis comorbidities: results from the National Psoriasis Foundation surveys 2003–2011. Dermatology (Basel, Switzerland). doi:10.1159/000342180
37. Favarato MH, Mease P, Goncalves CR, Goncalves Saad C, Sampaio-Barros PD, Goldenstein-Schainberg C (2014) Hypertension and diabetes significantly enhance the risk of cardiovascular disease in patients with psoriatic arthritis. Clin Exp Rheumatol 32(2):182–187
38. Dubreuil M, Rho YH, Man A, Zhu Y, Zhang Y, Love TJ, Ogdie A, Gelfand JM, Choi HK (2014) Diabetes incidence in psoriatic arthritis, psoriasis and rheumatoid arthritis: a UK population-based cohort study. Rheumatology (Oxford, England). doi:10.1093/rheumatology/ket343
39. Love TJ, Zhu Y, Zhang Y, Wall-Burns L, Ogdie A, Gelfand JM, Choi HK (2012) Obesity and the risk of psoriatic arthritis: a population-based study. Ann Rheum Dis 71(8):1273–1277. doi:10.1136/annrheumdis-2012-201299
40. Eder L, Jayakar J, Shanmugarajah S, Thavaneswaran A, Pereira D, Chandran V, Rosen CF, Gladman DD (2013) The burden of carotid artery plaques is higher in patients with psoriatic arthritis compared with those with psoriasis alone. Ann Rheum Dis 72(5):715–720. doi:10.1136/annrheumdis-2012-201497
41. Husted JA, Thavaneswaran A, Chandran V, Eder L, Rosen CF, Cook RJ, Gladman DD (2011) Cardiovascular and other comorbidities in patients with psoriatic arthritis: a comparison with patients with psoriasis. Arthritis Care Res 63(12):1729–1735. doi:10.1002/acr.20627
42. Armstrong AW, Voyles SV, Armstrong EJ, Fuller EN, Rutledge JC (2011) A tale of two plaques: convergent mechanisms of T-cell-mediated inflammation in psoriasis and atherosclerosis. Exp Dermatol 20(7):544–549. doi:10.1111/j.1600-0625.2011.01308.x
43. Wang Y, Gao H, Loyd CM, Fu W, Diaconu D, Liu S, Cooper KD, McCormick TS, Simon DI, Ward NL (2012) Chronic skin-specific inflammation promotes vascular inflammation and thrombosis. J Invest Dermatol 132(8):2067–2075. doi:10.1038/jid.2012.112
44. Ward NL, Umetsu DT (2014) A new player on the psoriasis block: IL-17A- and IL-22-producing innate lymphoid cells. J Invest Dermatol 134(9):2305–2307. doi:10.1038/jid.2014.216
45. Golden JB, Groft SG, Squeri MV, Debanne SM, Ward NL, McCormick TS, Cooper KD (2015) Chronic psoriatic skin inflammation leads to increased monocyte adhesion and aggregation. J Immunol (Baltimore, Md 1950). doi:10.4049/jimmunol.1402307
46. Ziats NP, Robertson AL Jr (1981) Effects of peripheral blood monocytes on human vascular cell proliferation. Atherosclerosis 38(3–4):401–410
47. Jiang Y, Beller DI, Frendl G, Graves DT (1992) Monocyte chemoattractant protein-1 regulates adhesion molecule expression and cytokine production in human monocytes. J Immunol (Baltimore Md: 1950) 148(8):2423–2428
48. Chen YL, Chang YJ, Jiang MJ (1999) Monocyte chemotactic protein-1 gene and protein expression in atherogenesis of hypercholesterolemic rabbits. Atherosclerosis 143(1):115–123
49. Yla-Herttuala S, Lipton BA, Rosenfeld ME, Sarkioja T, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D (1991) Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci USA 88(12):5252–5256
50. Liu XL, Zhang PF, Ding SF, Wang Y, Zhang M, Zhao YX, Ni M, Zhang Y (2012) Local gene silencing of monocyte chemoattractant protein-1 prevents vulnerable plaque disruption in apolipoprotein E-knockout mice. PLoS One 7(3):e33497. doi:10.1371/journal.pone.0033497
51. Rose S, Dave J, Millo C, Naik HB, Siegel EL, Mehta NN (2014) Psoriatic arthritis and sacroiliitis are associated with increased vascular inflammation by 18-fluorodeoxyglucose positron emission tomography computed tomography: baseline report from the psoriasis atherosclerosis and cardiometabolic disease initiative. Arthritis Res Ther 16(4):R161. doi:10.1186/ar4676
52. Rose S, Sheth NH, Baker JF, Ogdie A, Raper A, Saboury B, Werner TJ, Thomas P, Vanvoorhees A, Alavi A, Torigian DA, Gelfand JM, Mehta NN (2013) A comparison of vascular inflammation in psoriasis, rheumatoid arthritis, and healthy subjects by FDG-PET/CT: a pilot study. Am J Cardiovasc Dis 3(4):273–278
53. Mehta NN, Li K, Szapary P, Krueger J, Brodmerkel C (2013) Modulation of cardiometabolic pathways in skin and serum from patients with psoriasis. J Transl Med 11:194. doi:10.1186/1479-5876-11-194
54. Takeshita J, Mohler ER, Krishnamoorthy P, Moore J, Rogers WT, Zhang L, Gelfand JM, Mehta NN (2014) Endothelial cell-, platelet-, and monocyte/macrophage-derived microparticles are elevated in psoriasis beyond cardiometabolic risk factors. J Am Heart Assoc 3(1):e000507. doi:10.1161/jaha.113.000507
55. Li RC, Krishnamoorthy P, DerOhannessian S, Doveikis J, Wilcox M, Thomas P, Rader DJ, Reilly MP, Van Voorhees A, Gelfand JM, Mehta NN (2014) Psoriasis is associated with decreased plasma adiponectin levels independently of cardiometabolic risk factors. Clin Exp Dermatol 39(1):19–24. doi:10.1111/ced.12250
56. Rose S, Stansky E, Dagur PK, Samsel L, Weiner E, Jahanshad A, Doveikis J, Naik HB, Playford MP, McCoy JP, Mehta NN (2014) Characterization of immune cells in psoriatic adipose tissue. J Transl Med 12:258. doi:10.1186/s12967-014-0258-2
57. Boehncke S, Thaci D, Beschmann H, Ludwig RJ, Ackermann H, Badenhoop K, Boehncke WH (2007) Psoriasis patients show signs of insulin resistance. Br J Dermatol 157(6):1249–1251. doi:10.1111/j.1365-2133.2007.08190.x
58. Boehncke WH, Boehncke S, Tobin AM, Kirby B (2011) The ‘psoriatic march’: a concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol 20(4):303–307. doi:10.1111/j.1600-0625.2011.01261.x
59. Buerger C, Richter B, Woth K, Salgo R, Malisiewicz B, Diehl S, Hardt K, Boehncke S, Boehncke WH (2012) Interleukin-1beta interferes with epidermal homeostasis through induction of insulin resistance: implications for psoriasis pathogenesis. J Invest Dermatol 132(9):2206–2214. doi:10.1038/jid.2012.123
60. Schluter K, Diehl S, Lang V, Kaufmann R, Boehncke WH, Burger C (2015) Insulin resistance may contribute to upregulation of adhesion molecules on endothelial cells in psoriatic plaques. Acta Derm Venereol. doi:10.2340/00015555-2227
61. National Institutes of Health NH, Lung, and Blood Institute (2016) How is high blood cholesterol diagnosed? http://www.nhlbi.nih.gov/health/health-topics/topics/hbc/diagnosis. Accessed 1 Apr 2016
62. Mehta NN, Li R, Krishnamoorthy P, Yu Y, Farver W, Rodrigues A, Raper A, Wilcox M, Baer A, DerOhannesian S, Wolfe M, Reilly MP, Rader DJ, VanVoorhees A, Gelfand JM (2012) Abnormal lipoprotein particles and cholesterol efflux capacity in patients with psoriasis. Atherosclerosis 224(1):218–221. doi:10.1016/j.atherosclerosis.2012.06.068
63. Yu Y, Sheth N, Krishnamoorthy P, Saboury B, Raper A, Baer A, Ochotony R, Doveikis J, Derohannessian S, Voorhees AS, Torigian DA, Alavi A, Gelfand JM, Mehta NN (2012) Aortic vascular inflammation in psoriasis is associated with HDL particle size and concentration: a pilot study. Am J Cardiovasc Dis 2(4):285–292
64. Salahuddin T, Natarajan B, Playford MP, Joshi AA, Teague H, Masmoudi Y, Selwaness M, Chen MY, Bluemke DA, Mehta NN (2015) Cholesterol efflux capacity in humans with psoriasis is inversely related to non-calcified burden of coronary atherosclerosis. Eur Heart J. doi:10.1093/eurheartj/ehv339
65. Armstrong AW, Voyles SV, Armstrong EJ, Fuller EN, Rutledge JC (2011) Angiogenesis and oxidative stress: common mechanisms linking psoriasis with atherosclerosis. J Dermatol Sci 63(1):1–9. doi:10.1016/j.jdermsci.2011.04.007
66. Brezinski EA, Follansbee MR, Armstrong EJ, Armstrong AW (2014) Endothelial dysfunction and the effects of TNF inhibitors on the endothelium in psoriasis and psoriatic arthritis: a systematic review. Curr Pharm Des 20(4):513–528