Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice Research Datalink

Journal of Investigative Dermatology

Volumn 135, Issue 9, 2015, Pages 2189-2197

  Parisi, Rosa ^a   Rutter, Martin K ^b,c   Lunt, Mark ^c   Young, Helen S ^c   Symmons, Deborah P M ^c   Griffiths, Christopher E M ^c   Ashcroft, Darren M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE CORONARY SYNDROME; ADULT; AGE DISTRIBUTION; ARTHRITIS; ARTICLE; ATRIAL FIBRILLATION; BODY MASS; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; CHRONIC KIDNEY DISEASE; COHORT ANALYSIS; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DISEASE ASSOCIATION; FEMALE; HEART INFARCTION; HUMAN; HYPERTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PREVALENCE; PRIORITY JOURNAL; PSORIASIS; SEX DIFFERENCE; SMOKING; SOCIAL STATUS; THROMBOEMBOLISM; TRANSIENT ISCHEMIC ATTACK; UNSTABLE ANGINA PECTORIS; VALVULAR HEART DISEASE; AGED; ANGINA, UNSTABLE; CARDIOVASCULAR DISEASES; CASE CONTROL STUDY; COMORBIDITY; COMPARATIVE STUDY; CONFIDENCE INTERVAL; FACTUAL DATABASE; MULTIVARIATE ANALYSIS; MYOCARDIAL INFARCTION; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SEX RATIO; STROKE; SURVIVAL; YOUNG ADULT;

ACUTE CORONARY SYNDROME; ADULT; AGE DISTRIBUTION; AGED; ANGINA, UNSTABLE; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; COMORBIDITY; CONFIDENCE INTERVALS; DATABASES, FACTUAL; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; MYOCARDIAL INFARCTION; PREVALENCE; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PSORIASIS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SEX DISTRIBUTION; STROKE; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 84939432672     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2015.87     Document Type: Article

References (42)

1. Ahlehoff O, Gislason GH, Charlot M et al. (2011) Psoriasis is associated with clinically significant cardiovascular risk: a Danish Nationwide Cohort Study. J Intern Med 270: 147-57
2. Ahlehoff O, Gislason GH, Jørgensen CH et al. (2012) Psoriasis and risk of atrial fibrillation and ischaemic stroke: a Danish Nationwide Cohort Study. Eur Heart J 33: 2054-64
3. Boehncke W-H, Boehncke S, Tobin A-M et al. (2011) The 'psoriatic march': a concept of how severe psoriasis may drive cardiovascular comorbidity. Exp Dermatol 20: 303-7
4. Brauchli YB, Jick SS, Miret M et al. (2009) Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis. Br J Dermatol 160: 1048-56
5. Department for Communities and Local Government (2010) English indices of deprivation 2010: guidance. ? https://www.gov.uk/government/publications/english-indices-of-deprivation-2010-guidance? Accessed on 21 May 2014
6. Dowlatshahi EA, Kavousi M, Nijsten T et al. (2013) Psoriasis is not associated with atherosclerosis and incident cardiovascular events: the Rotterdam Study. J Invest Dermatol 133: 2347-54
7. Dregan A, Charlton J, Chowienczyk P et al. (2014) Chronic inflammatory disorders and risk of type 2 diabetes mellitus, coronary heart disease, and stroke: a population-based cohort study. Circulation 130: 837-44
8. Erik von E, Douglas GA, Matthias E et al. (2007) Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Br Med J 335: 806-8
9. Gelfand JM, Berlin J, Van Voorhees A et al. (2003) Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in the United Kingdom. Arch Dermatol 139: 1425-9
10. Gelfand JM, Dommasch ED, Shin DB (2009) The risk of stroke in patients with psoriasis. J Invest Dermatol 129: 2411-8
11. Gelfand JM, Feldman SR, Stern RS et al. (2004) Determinants of quality of life in patients with psoriasis: a study from the US population. J Am Acad Dermatol 51: 704-8
12. Gelfand JM, Neimann AL, Shin DB et al. (2006) Risk of myocardial infarction in patients with psoriasis. JAMA 296: 1735-41
13. Griffiths CEM, Barker JNWN (2007) Pathogenesis and clinical features of psoriasis. Lancet 370: 263-71
14. Gulliford MC, Charlton J, Ashworth M et al. (2009) Selection of medical diagnostic codes for analysis of electronic patient records. Application to stroke in a primary care database. PLoS One 4: e7168
15. Han C, Robinson DW, Hackett MV et al. (2006) Cardiovascular disease and risk factors in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. J Rheumatol 33: 2167-72
16. Herrett E, Thomas SL, Schoonen WM et al. (2010) Validation and validity of diagnoses in the General Practice Research Database: a systematic review. Br J Clin Pharmacol 69: 4-14
17. Jick H, Jick SS, Derby LE (1991) Validation of information recorded on general practitioner based computerised data resource in the United Kingdom. Br Med J 302: 766-8
18. John H, Kitas G (2012) Inflammatory arthritis as a novel risk factor for cardiovascular disease. Eur J Intern Med 23: 575-9
19. Kaye JA, Li L, Jick SS (2008) Incidence of risk factors for myocardial infarction and other vascular diseases in patients with psoriasis. Br J Dermatol 159: 895-902
20. Khan NF, Harrison SE, Rose PW (2010) Validity of diagnostic coding within the General Practice Research Database: a systematic review. Br J Gen Pract 60: e128-36
21. Lee M-S, Lin R-Y, Lai M-S (2014) Increased risk of diabetes mellitus in relation to the severity of psoriasis, concomitant medication, and comorbidity: A nationwide population-based cohort study. J Am Acad Dermatol 70: 691-8
22. Li WQ, Han JL, Manson JE (2012) Psoriasis and risk of nonfatal cardiovascular disease in U.S. women: a cohort study. Br J Dermatol 166: 811-8
23. Lin HW, Wang KH, Lin HC (2011) Increased risk of acute myocardial infarction in patients with psoriasis: a 5-year population-based study in Taiwan. J Am Acad Dermatol 64: 495-501
24. Ludwig RJ, Herzog C, Rostock A et al. (2007) Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol 156: 271-6
25. Mallbris L, Akre O, Granath F (2004) Increased risk for cardiovascular mortality in psoriasis inpatients but not in outpatients. Eur J Epidemiol 19: 225-30
26. Mehta NN, Azfar RS, Shin DB (2010) Patients with severe psoriasis are at increased risk of cardiovascular mortality: cohort study using the General Practice Research Database. Eur Heart J 31: 1000-6
27. Naldi L, Chatenoud L, Linder D et al. (2005) Cigarette smoking, body mass index, and stressful life events as risk factors for psoriasis: results from an Italian Case-Control Study. J Invest Dermatol 125: 61-7
28. Neimann AL, Shin DB, Wang X et al. (2006) Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol 55: 829-35
29. Nijsten T, Wakkee M (2009) Complexity of the association between psoriasis and comorbidities. J Invest Dermatol 129: 1601-3
30. Ogdie A, Yu Y, Haynes K et al. (2015) Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study. Ann Rheum Dis 74: 326-32
31. Parisi R, Symmons DPM, Griffiths CEM et al. (2013) Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol 133: 377-85
32. Rapp SR, Feldman SR, Exum ML et al. (1999) Psoriasis causes as much disability as other major medical diseases. J Am Acad Dermatol 41: 401-7
33. Robinson D, Schulz E, Brown P et al. (1997) Updating the read codes: userinteractive maintenance of a dynamic clinical vocabulary. J Am Med Inform Assoc 4: 465-72
34. Samarasekera EJ, Neilson JM, Warren RB et al. (2013) Incidence of cardiovascular disease in individuals with psoriasis: a systematic review and meta-analysis. J Invest Dermatol 133: 2340-6
35. Samarasekera EJ, Smith CH (2014) Psoriasis: guidance on assessment and referral. Clin Med 14: 178-82
36. Setty AR, Curhan G, Choi HK (2007) Obesity, waist circumference, weight change, and the risk of psoriasis in women: Nurses' health study II. Arch Int Med 167: 1670-5
37. Springate DA, Kontopantelis E, Ashcroft DM et al. (2014) ClinicalCodes: an online clinical codes repository to improve the validity and reproducibility of research using electronic medical records. PLoS One 9: e99825
38. Stern RS, Huibregtse A (2011) Very severe psoriasis is associated with increased noncardiovascular mortality but not with increased cardiovascular risk. J Invest Dermatol 131: 1159-66
39. Stern RS, Nijsten T, Feldman SR et al. (2004) Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. J Invest Dermatol Symp Proc 9: 136-9
40. Symmons DPM, Gabriel SE (2011) Epidemiology of CVD in rheumatic disease, with a focus on RA and SLE. Nat Rev Rheumatol 7: 399-408
41. Wakkee M, Herings RM, Nijsten T (2010) Psoriasis may not be an independent risk factor for acute ischemic heart disease hospitalizations: results of a large population-based Dutch cohort. J Invest Dermatol 130: 962-7
42. Westlake SL, Colebatch AN, Baird J et al. (2010) The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review. Rheumatology (Oxford) 49: 295-307