Novel imatinib-loaded silver nanoparticles for enhanced apoptosis of human breast cancer MCF-7 cells

Artificial Cells, Nanomedicine and Biotechnology

Volumn 45, Issue 6, 2017, Pages 1082-1091

  Sadat Shandiz, Seyed Ataollah ^a   Shafiee Ardestani, Mehdi ^b   Shahbazzadeh, Delavar ^c   Assadi, Artin ^b   Ahangari Cohan, Reza ^c   Asgary, Vahid ^d   Salehi, Soheil ^e  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c PASTEUR INSTITUTE OF IRAN   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

Apoptosis; imatinib; MCF 7; silver nanoparticles

Indexed keywords

CELL CULTURE; CELL DEATH; CELLS; CYTOLOGY; DISEASES; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GENE EXPRESSION; METAL NANOPARTICLES; NANOPARTICLES; POLYMERASE CHAIN REACTION; SYNTHESIS (CHEMICAL); VOLTAGE DIVIDERS;

DRUG DELIVERY SYSTEM; HUMAN BREAST CANCER CELLS; IMATINIB; MCF-7; REAL-TIME PCR METHOD; SILVER NANOPARTICLES; SILVER NANOPARTICLES (AGNPS); VISIBLE SPECTROSCOPY;

SILVER;

IMATINIB; NANOCARRIER; PROTEIN BAX; PROTEIN BCL 2; SILVER NANOPARTICLE; BAX PROTEIN, HUMAN; BCL2 PROTEIN, HUMAN; METAL NANOPARTICLE; SILVER;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; DRUG DELIVERY SYSTEM; DRUG RELEASE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INFRARED SPECTROSCOPY; MCF-7 CELL LINE; REAL TIME POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; BREAST TUMOR; CHEMISTRY; DRUG EFFECTS; FEMALE; METABOLISM; PATHOLOGY; PROCEDURES;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; IMATINIB MESYLATE; MCF-7 CELLS; METAL NANOPARTICLES; PROTO-ONCOGENE PROTEINS C-BCL-2; SILVER;

EID: 84976554513     PISSN: 21691401     EISSN: 2169141X     Source Type: Journal    
DOI: 10.1080/21691401.2016.1202257     Document Type: Article

References (34)

1. Ahluwalia V, Kumar J, Sisodia R, Shakil NA, Walia S., 2014. Green synthesis of silver nanoparticles by Trichoderma harzianum andtheir bio-efficacy evaluation against Staphylococcus aureus and Klebsiella pneumonia Vivek. Ind Crop Prod. 55:202–206.
2. Arora A, Scholar EM., 2005. Role of tyrosine kinase inhibitors in cancer therapy. J Pharmacol Exp Ther. 315:971–979.
3. Bar H, Bhui DK, Sahoo GP, Sarkar P, De SP, Misra A., 2009. Green synthesis of silver nanoparticles using latex of Jatropha curcas. Colloids Surf a Physicochem Eng Aspects. 339:134–139.
4. Bhattacharyya S, Kudgus RA, Bhattacharya R, Mukherjee P., 2011. Inorganic nanoparticles in cancer therapy. Pharm Res. 28:237–259.
5. Blay JY, Rutkowski P., 2014. Adherence to imatinib therapy in patients with gastrointestinal stromal tumors. Cancer Treat Rev. 40:242–247.
6. Conde J, Doria G, Baptista P., 2012. Noble metal nanoparticles applications in cancer. J Drug Deliv. 2012:751075. doi:10.1155/2012/751075.
7. Dash S, Murthy PN, Nath L, Chowdhury P., 2010. Kinetic modeling on drug release from controlled drug delivery systems. Acta Pol Pharm Drug Res. 67:217–223.
8. Dicheva BM, Koning GA., 2014. Targeted thermosensitive liposomes:an attractive novel approach for increased drug delivery to solid tumors. Expert Opin Drug Deliv. 11:83–100.
9. Dikpati A, Madgulkar A, Kshirsagar SJ, Bhalekar M, Chahal AS., 2012. Targeted drug delivery to CNS using nanoparticles. JAPS J. 2:179–191.
10. Gupta B, Poudel BK, Tran TH, Pradhan R, Cho HJ, Jeong JH, et al. 2015. Modulation of pharmacokinetic and cytotoxicity profile of imatinib base by employing optimized nanostructured lipid carriers. Pharm Res. 32:2912–2927.
11. Hasadsri L, Kreuter J, Hattori H, Iwasaki T, George JM., 2009. Functional protein delivery into neurons using polymeric nanoparticles. J Biol Chem. 284:6972–6981.
12. He J, Xu H, Yang Y, Zhang X, Li X-M., 2004. Neuroprotective effects of olanzapine on methamphetamine-induced neurotoxicity are associated with an inhibition of hyperthermia and prevention of Bcl-2 decrease in rats. Brain Res. 1018:186–192.
13. He Y, Du Z, Ma SH, Yue L, Li D, Huang H, Jiang S, et al. 2016. Effects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors in vivo. Int J Nanomed. 11:1879–1887.
14. Karimi N, Aghasadeghi MR, Yaghmaei P, Moghaddam HF, Nassiri-Koopaei N, Moloudian H, et al. 2014. Anionic linear globular dendrimer-G2-ciprofloxacin nano-conjugate:novel agent against Wilson disease cell model. Lett Drug Des Discov. 11:908–916.
15. Kumar DA, Palanichamy V, Roopan SM., 2014. Green synthesis of silver nanoparticles using Alternanthera dentata leaf extract at room temperature and their antimicrobial activity. Spectrochim Acta A Mol Biomol Spectrosc. 127:168–171.
16. Loo YY, Chieng BW, Nishibuchi M, Radu S., 2012. Synthesis of silver nanoparticles by using tea leaf extract from Camellia sinensis. Int J Nanomedicine. 7:4263–4267.
17. Magudapathy P, Gangopadhyay P, Panigrahi BK, Nair KGM, Dhara S., 2001. Electrical transport studies of Ag nanoclusters embedded in glass matrix. Physica B. 299:142–146.
18. Mello VAD, Ricci-Júnior E., 2011. Encapsulation of naproxen in nanostructured system:structural characterization and in vitro release studies. Quim Nova. 34:933–939.
19. Nasrabadi MR, Pourmortazavi SM, Sadat Shandiz SA, Ahmadi F, Batooli H., 2014. Green synthesis of silver nanoparticles using Eucalyptus leucoxylon leaves extract and evaluating the antioxidant activities of extract. Nat Pro Res. 28:1964–1969.
20. Odintsova E, Van Niel G, Conjeaud H, Raposo G, Iwamoto R, Mekada E., 2013. Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptor. J Biol Chem. 288:26323–26334.
21. Pawson T, Warner N., 2007. Oncogenic re-wiring of cellular signaling pathways. Oncogene. 26:1268–1275.
22. Rani D, Somasundaram VH, Nair S, Koyakutty M., 2012. Advances in cancer nanomedicine. J Indian Inst Sci. 92:187–218.
23. Riedy MC, Muiread KA, Jensen CP, Stewart CC., 1991. Use of a photolabeling technique to identify nonviable cells in fixed homologous or heterologous cell populations. Cytometry. 12:133–139.
24. Sadat Shandiz SA, Farasati S, Saeedi B, Baghbani-Aarani F, Akbari Asl E, Keshavarz-Pakseresht B, et al. 2016a. Up regulation of KAI1 gene expression and apoptosis effect of imatinib mesylate in gastric adenocarcinoma (AGS) cell line. Asian Pac J Trop Dis. 6:120–125.
25. Sadat Shandiz SA, Khosravani M, Mohammadi S, Noorbazargan H, Mirzaie A, et al. 2016b. Evaluation of imatinib mesylate (Gleevec) on KAI1/CD82 gene expression in breast cancer MCF-7 cells using quantitative real-time PCR. Asian Pac J Trop Biomed. 6:159–163.
26. Sadat Shandiz SA, Shafiee Ardestani M, Irani SH, Shahbazzadeh D., 2015. Imatinib induces down regulation of Bcl-2 an anti-apoptotic protein in prostate cancer PC-3 cell line. Adv Stud Biol. 7:17–27.
27. Salehi S, Shandiz SAS, Ghanbar F, Darvish MR, Shafiee Ardestani M, Mirzaie A, Jafari M., 2016. Phyto-synthesis of silver nanoparticles using Artemisia marschalliana Sprengel aerial parts extract and assessment of their antioxidant, anticancer, and antibacterial properties. Int J Nanomed. 11:1835–1846.
28. Singh S, Pandey VK, Tewari RP, Agarwal V., 2011. Nanoparticle based drug delivery system:advantages and applications. Indian J Sci Technol. 4:177–180.
29. Sivasankar M, Kumar BP., 2010. Role of nanoparticles in drug delivery system. Int J Res Pharm Biomed Sci. 1:41–66.
30. Tripathi A, Chandrasekaran N, Raichur AM, Mukherjee A., 2009. Antibacterial applications of silver nanoparticles synthesized by aqueous extract of Azadirachta indica (Neem) leaves. J Biomed Nanotechnol. 5:93–98.
31. Woo SM, Choi YK, Kim AJ, Cho SG, Ko SG., 2015. P53 causes butein-mediated apoptosis of chronic myeloid leukemia cells. Mol Med Rep. 13:1091–1096.
32. Yang J, Wang H, Wang Z, Tan X, Song C, Zhang R, Li J., 2009. Interaction between antitumor drug and silver nanoparticles:combined fluorescence and surface enhanced Raman scattering study. Chinese Optics Lett. 7:894–897.
33. Zayed MF, Eisa WH, Shabaka AA., 2012. Malva parviflora extract assisted green synthesis of silver nanoparticles. Spectrochim Acta A Mol Biomol Spectrosc. 98:423–428.
34. Zhang J, Yang PL, Gray NS., 2009. Targeting cancer with small molecule kinase inhibitors. Nat Rev Cancer. 9:28–39.