The Effect of NO Donor on Calcium Uptake and Reactive Nitrogen Species Production in Mitochondria

Cellular Physiology and Biochemistry

Volumn 39, Issue 1, 2016, Pages 193-204

  Akopova, Olga ^a   Kotsiuruba, Anatoly ^a   Korkach, Yulia ^a   Kolchinskaya, Liudmila ^a   Nosar, Valentina ^a   Gavenauskas, Bronislav ^a   Serebrovska, Zoya ^a   Mankovska, Iryna ^a   Sagach, Vadim ^a  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

Author keywords

Calcium; Mitochondria; Mitochondrial NO synthase; Nitric oxide; Nitroglycerine; Permeability transition pore; Reactive nitrogen and oxygen species

Indexed keywords

CALCIUM; CALCIUM CHLORIDE; CITRULLINE; GLYCERYL TRINITRATE; HYDROPEROXIDE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; REACTIVE NITROGEN SPECIES; CARRIER PROTEIN; HYDROGEN PEROXIDE; NITRIC ACID DERIVATIVE; NITRIC OXIDE DONOR; NITRITE; S NITROSOTHIOL;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART MITOCHONDRION; IN VIVO STUDY; LIVER MITOCHONDRION; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECT; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; CITRULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN PEROXIDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; NITRATES; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; NITRITES; NITROGLYCERIN; RATS, WISTAR; REACTIVE NITROGEN SPECIES; S-NITROSOTHIOLS;

EID: 84976543992     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000445616     Document Type: Article

References (40)

1. O'Donnell ME, Owen NE: Regulation of ion pumps and carriers in vascular smooth muscle. Physiol Rev 1994;74:683-721
2. Yuan X-J, Tod ML, Rubin LJ, Blaustein MP: NO hyperpolarizes pulmonary artery smoth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels. Proc Natl Acad Sci USA 1996;93:10489-10494
3. Barsukova A, Komarov A, Hajnoczky G, Bernardi P, Bourdette D, Forte M: Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons Eur J Neurosci 2011;33:831-842
4. Rizzuto R, De Stefani D, Raffaello A, Mammucari C: Mitochondria as sensors and regulators of calcium signaling. Mol Cell Biol 2012;13:566-578
5. Szabadkai G, Rizzuto R Participation of endoplasmic reticulum and mitochondrial calcium handling in apoptosis: more than just neighborhood? FEBS Lett 2004;567:111-115
6. Xie Y, Xiao F, Luo L, Zhong C: Activation of autophagy protects against ROS-mediated mitochondria-dependent apoptosis in L-02 hepatocytes induced by Cr(VI). Cell Physiol Biochem 2014;33:705-716
7. Schweizer M, Richter Ch: Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. Biochem Biophys Res Commun 1994;204:169-175
8. Rakhit RD, Mojet MH, Marber MS, Duchen MR: Mitochondria as targets for nitric oxide-induced protection during simulated ischemia and reoxygenation in isolated neonatal cardiomyocytes. Circulation 2001;103:2617-2623
9. Brookes PS, Salinas EP, Darley-Usmar K, Eiserich JP, Freeman BA, Darley-Usmar VM, Anderson PG: Concentration-dependent effects of nitric oxide on mitochondrial permeability transition and cytochrome c release. J Biol Chem 2000;275:20474-20479
10. Halestrap AP, Kerr PM, Javadov S, Woodfield KY: Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1998;1366:79-94
11. Bernardi P, Rasola A, Forte M, Lippe G: The mitochondrial permeability transition pore: channel formation by F-ATP synthase, integration in signal transduction, and role in pathophysiology. Physiol Rev 2015;95:1111-1155
12. Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS: Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol 2004;287:C817-C833
13. Feissner RF, Skalska J, Gaum WE, Sheu SS: Crosstalk signaling between mitochondrial Ca2+ and ROS. Front Biosci 2009;14:1197-1218
14. Csordas G, Hajnoczky G: SR/ER-mitochondrial local communication: calcium and ROS. Biochim Biophys Acta 2009;1787:1352-1362
15. Brookes PS: Mitochondrial nitric oxide synthase. Mitochondrion 2004;3:187-204
16. Murphy MP: How mitochondria produce reactive oxygen species. Biochem J 2009;417:1-13
17. Klatt P, Schmidt K, Uray G, Mayer B: Multiple catalytic functions of brain nitric oxide synthase. Biochemical characterization, cofactor requirement, and the role of N-hydroxy-L-arginine as an intermediate. J Biol Chem 1993;268:14781-14787
18. Gunter TE, Sheu SS: Characteristics and possible functions of mitochondrial Ca(2+) transport mechanisms. Biochim Biophys Acta 2009;1787:1291-1308
19. McCormak JG, Denton RM: Mitochondrial Ca2+ transport and the role of intramitochondrial Ca2+ in the regulation of energy metabolism. Dev Neurosci 1993;15:165-173
20. Dedkova EN, Ji X, Lipsius SL, Blatter LA: Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells. Am J Physiol 2004;286:C406-C415
21. Åkerman KEO, Wikström MKF: Safranine as a probe of the mitochondrial membrane potential. FEBS Lett 1976;68:191-197
22. Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR: Analysis of nitrite, nitrate and [15N]nitrate in biological fluids. Anal Biochem 1982;126:131-138
23. Pfeiffer S, Gorren ACF, Schmidt K, Werner ER, Hansert B, Bohle DS, Mayer B: Metabolic fate of peroxynitrite in aqueous solution. J Biol Chem 1997;272:3465-3470
24. Percival MD, Ouellet M, Campagnolo Ch, Claveau D, Li Ch: Inhibition of cathepsin K by nitric oxide donors: evidence for the formation of mixed disulfides and a sulfenic acid. Biochemistry 1999;38:13574-13583
25. Buga GM, Singh R, Pervin S, Rogers NE, Schmitz DA, Jenkinson CP, Cederbaum SD, Ignarro LJ: Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production. Am J Physiol 1996;271:H1988-H1998
26. Huwiler M, Kohler H: Pseudo-catalytic degradation of hydrogen peroxide in the lactoperoxidase/H2O2/ iodide system. Eur J Biochem 1984;141:69-74
27. Bernardi P, von Stockum S: The permeability transition pore a Ca2+ release channel: new answers to an old question. Cell Calcium 2012;52:22-27
28. von Stockum S, Giorgio V, Trevisan E, Lippe G, Glick GD, Forte MA, Da-Re C, Checchetto V, Mazzotta G, Costa R, Szabo I, Bernardi PF: ATPase of D. melanogaster forms 53 picosiemen (53-pS) channels responsible for mitochondrial Ca2+-induced Ca2+ release. J Biol Chem 2015;290:4537-4544
29. Mather M, Rottenberg H: Ageing enhances the activation of the permeability transition pore in mitochondria. Biochem Biophys Res Commun 2000;273:603-608
30. De Paulis D, Chiari P, Teixeira G, Couture-Lepetit E, Abrial M, Argaud L, Gharib A, Ovize M: Cyclosporine A at reperfusion fails to reduce infarct size in the in vivo rat heart. Basic Res Cardiol 2013;108:379-390
31. Broekemeier KM, Schmid PC, Schmid HHO, Pfeiffer DR: Effects of phospholipase A2 inhibitors on ruthenium red-induced Ca2+ release from mitochondria. J Biol Chem 1985;260:105-113
32. Chernyak BV, Bernardi P: The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. Eur J Biochem 1996;238:623-630
33. Borutaite V, Brown GC: S-nitrosothiol inhibition of mitochondrial complex I causes a reversible increase in mitochondrial hydrogen peroxide production. Biochim Biophys Acta 2006;1757:562-566
34. Nguyen TT, Stevens MV, Kohr M, Steenbergen C, Sack MN, Murphy E: Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore. J Biol Chem 2011;286:40184-40192
35. Ignarro LJ, Napoli C, Loscalzo J: Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide. Circ Res 2002;90:P.21-28
36. Akopova OV, Kolchinskaya LI, Nosar VI, Bouryi VA, Mankovska IN, Sagach VF: Effect of potential-dependent potassium uptake on production of reactive oxygen species in rat brain mitochondria. Biochemistry (Moscow) 2014;79:44-53
37. Wang R, Liu Y, Liu X, Jia Sh, Zhao J, Cui D, Wang L: Resveratrol protects neurons and the myocardium by reducing oxidative stress and ameliorating mitochondria damage in a cerebral ischemia rat model. Cell Physiol Biochem 2014;34:854-864
38. Zoratti M, De Marchi U, Gulbins E, Szabo I: Novel channels of the inner mitochondrial membrane. Biochim Biophys Acta 2009;1787:351-363
39. Huser J, Blatter LA: Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition pore. Biochem J 1999;343:311-317
40. Petronilli V, Miotto G, Canton M, Brini M, Colonna R, Bernardi P, Di Lisa F: Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence. Biophys J 1999;76:725-734