The application of digital pathology to improve accuracy in glomerular enumeration in renal biopsies

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Rosenberg, Avi Z ^a,b   Palmer, Matthew ^c   Merlino, Lino ^d   Troost, Jonathan P ^e   Gasim, Adil ^f   Bagnasco, Serena ^g   Avila Casado, Carmen ^h   Johnstone, Duncan ⁱ   Hodgin, Jeffrey B ^e   Conway, Catherine ^j   Gillespie, Brenda W ^k   Nast, Cynthia C ^l   Barisoni, Laura ^d   Hewitt, Stephen M ^j  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h TORONTO GENERAL HOSPITAL   (Canada)

ⁱ TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j NATIONAL CANCER INSTITUTE   (United States)

^k UNIVERSITY OF MICHIGAN   (United States)

^l CEDARS SINAI MEDICAL CENTER   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DIGITAL PATHOLOGY; FOCAL GLOMERULOSCLEROSIS; GLOMERULOSCLEROSIS; GLOMERULUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOGLOBULIN A NEPHROPATHY; INTERMETHOD COMPARISON; KIDNEY BIOPSY; MAJOR CLINICAL STUDY; MEMBRANOUS GLOMERULONEPHRITIS; MICROSCOPY; MINIMAL CHANGE GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; BIOPSY; CLINICAL TRIAL; DIAGNOSTIC IMAGING; GLOMERULONEPHRITIS, IGA; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; PATHOLOGY; PROCEDURES; SIGNAL PROCESSING;

BIOPSY; GLOMERULONEPHRITIS, IGA; GLOMERULONEPHRITIS, MEMBRANOUS; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; HUMANS; KIDNEY GLOMERULUS; MICROSCOPY; NEPHROTIC SYNDROME; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 84976448535     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0156441     Document Type: Article

References (22)

1. Walker PD, Cavallo T, Bonsib SM, Ad Hoc Committee on Renal Biopsy Guidelines of the Renal Pathology S. Practice guidelines for the renal biopsy. Modern pathology: an official journal of the United States and Canadian Academy of Pathology, Inc. 2004; 17(12):1555-63. doi: 10.1038/modpathol.3800239PMID: 15272280.
2. Muehrcke RC, Kark RM, Pirani CL, Pollak VE. Lupus nephritis: a clinical and pathologic study based on renal biopsies. Medicine. 1957; 36(1):1-145. PMID: 13418117.
3. Pirani CL, Pollak VE, Schwartz FD. The Reproducibility of Semiquantitative Analyses of Renal Histology. Nephron. 1964; 1:230-7. PMID: 14263632.
4. Weening JJ, D'Agati VD, Schwartz MM, Seshan SV, Alpers CE, Appel GB, et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. Journal of the American Society of Nephrology: JASN. 2004; 15(2):241-50. PMID: 14747370.
5. Gambara V, Mecca G, Remuzzi G, Bertani T. Heterogeneous nature of renal lesions in type II diabetes. Journal of the American Society of Nephrology: JASN. 1993; 3(8):1458-66. PMID: 8490117.
6. Tervaert TW, Mooyaart AL, Amann K, Cohen AH, Cook HT, Drachenberg CB, et al. Pathologic classification of diabetic nephropathy. Journal of the American Society of Nephrology: JASN. 2010; 21 (4):556-63. doi: 10.1681/ASN.2010010010 PMID: 20167701.
7. Working Group of the International Ig ANN, the Renal Pathology S, Roberts IS, Cook HT, Troyanov S, Alpers CE, et al. The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Kidney international. 2009; 76(5):546-56. doi: 10.1038/ki.2009.168 PMID: 19571790.
8. Austin HA 3rd, Balow JE. Henoch-Schonlein nephritis: prognostic features and the challenge of therapy. American journal of kidney diseases: the official journal of the National Kidney Foundation. 1983; 2(5):512-20. PMID: 6338708.
9. Solez K, Axelsen RA, Benediktsson H, Burdick JF, Cohen AH, Colvin RB, et al. International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology. Kidney international. 1993; 44(2):411-22. PMID: 8377384.
10. Sethi S, Haas M, Markowitz GS, D'Agati VD, Rennke HG, Jennette JC, et al. Mayo Clinic/Renal Pathology Society Consensus Report on Pathologic Classification, Diagnosis, and Reporting of GN. Journal of the American Society of Nephrology: JASN. 2015. doi: 10.1681/ASN.2015060612 PMID: 26567243.
11. Barisoni L, Nast CC, Jennette JC, Hodgin JB, Herzenberg AM, Lemley KV, et al. Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE). Clinical journal of the American Society of Nephrology: CJASN. 2013; 8(8):1449-59. doi: 10.2215/CJN.08370812 PMID: 23393107; PubMed Central PMCID: PMC3731905.
12. Nast CC, Lemley KV, Hodgin JB, Bagnasco S, Avila-Casado C, Hewitt SM, et al. Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes. Seminars in nephrology. 2015; 35(3):266-78. doi: 10.1016/j.semnephrol.2015.04.006 PMID: 26215864.
13. Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PX, Barisoni L, et al. Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach. Kidney international. 2013; 83(4):749-56. doi: 10.1038/ki.2012.428 PMID: 23325076; PubMed Central PMCID: PMC3612359.
14. Fine JL. 21(st) century workflow: A proposal. Journal of pathology informatics. 2014; 5:44. doi: 10. 4103/2153-3539.145733 PMID: 25535592; PubMed Central PMCID: PMC4260324.
15. Ozluk Y, Blanco PL, Mengel M, Solez K, Halloran PF, Sis B. Superiority of virtual microscopy versus light microscopy in transplantation pathology. Clinical transplantation. 2012; 26(2):336-44. doi: 10. 1111/j.1399-0012.2011.01506.x PMID: 21955102.
16. Jen KY, Olson JL, Brodsky S, Zhou XJ, Nadasdy T, Laszik ZG. Reliability of whole slide images as a diagnostic modality for renal allograft biopsies. Human pathology. 2013; 44(5):888-94. doi: 10.1016/j. humpath.2012.08.015 PMID: 23199528.
17. Barisoni L, Jennette JC, Colvin R, Sitaraman S, Bragat A, Castelli J, et al. Novel quantitative method to evaluate globotriaosylceramide inclusions in renal peritubular capillaries by virtual microscopy in patients with fabry disease. Archives of pathology & laboratory medicine. 2012; 136(7):816-24. doi: 10. 5858/arpa.2011-0350-OA PMID: 22742555.
18. Imasawa T, Nakazato T, Ikehira H, Fujikawa H, Nakajima R, Ito T, et al. Predicting the outcome of chronic kidney disease by the estimated nephron number: the rationale and design of PRONEP, a prospective, multicenter, observational cohort study. BMC nephrology. 2012; 13:11. doi: 10.1186/1471-2369-13-11 PMID: 22405377; PubMed Central PMCID: PMC3376039.
19. Tsuboi N, Kawamura T, Koike K, Okonogi H, Hirano K, Hamaguchi A, et al. Glomerular density in renal biopsy specimens predicts the long-term prognosis of IgA nephropathy. Clinical journal of the American Society of Nephrology: CJASN. 2010; 5(1):39-44. doi: 10.2215/CJN.04680709 PMID: 19965542; PubMed Central PMCID: PMC2801658.
20. Tsuboi N, Kawamura T, Miyazaki Y, Utsunomiya Y, Hosoya T. Low glomerular density is a risk factor for progression in idiopathic membranous nephropathy. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association-European Renal Association. 2011; 26(11):3555-60. doi: 10.1093/ndt/gfr399 PMID: 21771759.
21. Tsuboi N, Utsunomiya Y, Kanzaki G, Koike K, Ikegami M, Kawamura T, et al. Low glomerular density with glomerulomegaly in obesity-related glomerulopathy. Clinical journal of the American Society of Nephrology: CJASN. 2012; 7(5):735-41. doi: 10.2215/CJN.07270711 PMID: 22403274.
22. Corwin HL, Schwartz MM, Lewis EJ. The importance of sample size in the interpretation of the renal biopsy. American journal of nephrology. 1988; 8(2):85-9. PMID: 3394725.