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Volumn 6, Issue , 2016, Pages

Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE 2; PPP2R1A PROTEIN, HUMAN; PROTEIN C JUN; PROTEIN KINASE P60;

EID: 84976444766     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep27391     Document Type: Article
Times cited : (30)

References (56)
  • 1
    • 0020660717 scopus 로고
    • Two pathogenetic types of endometrial carcinoma
    • Bokhman, J. V. Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 15, 10-17 (1983).
    • (1983) Gynecol Oncol , vol.15 , pp. 10-17
    • Bokhman, J.V.1
  • 2
    • 33644848579 scopus 로고    scopus 로고
    • Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers
    • Hamilton, C. A. et al. Uterine papillary serous and clear cell carcinomas predict for poorer survival compared to grade 3 endometrioid corpus cancers. Br J Cancer 94, 642-646 (2006).
    • (2006) Br J Cancer , vol.94 , pp. 642-646
    • Hamilton, C.A.1
  • 3
    • 84867324518 scopus 로고    scopus 로고
    • Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses
    • Kuhn, E. et al. Identification of molecular pathway aberrations in uterine serous carcinoma by genome-wide analyses. J Natl Cancer Inst 104, 1503-1513 (2012).
    • (2012) J Natl Cancer Inst , vol.104 , pp. 1503-1513
    • Kuhn, E.1
  • 5
    • 23644444497 scopus 로고    scopus 로고
    • Ovarian cancer is a heterogeneous disease
    • Wang, V. et al. Ovarian cancer is a heterogeneous disease. Cancer Genet Cytogenet 161, 170-173 (2005).
    • (2005) Cancer Genet Cytogenet , vol.161 , pp. 170-173
    • Wang, V.1
  • 6
    • 84924048777 scopus 로고    scopus 로고
    • Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing
    • Lee, J. Y. et al. Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing. BMC Cancer 15, 85 (2015).
    • (2015) BMC Cancer , vol.15 , pp. 85
    • Lee, J.Y.1
  • 7
    • 84870532434 scopus 로고    scopus 로고
    • Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
    • Le Gallo, M. et al. Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes. Nat Genet 44, 1310-1315 (2012).
    • (2012) Nat Genet , vol.44 , pp. 1310-1315
    • Le Gallo, M.1
  • 8
    • 84885092663 scopus 로고    scopus 로고
    • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
    • Bashashati, A. et al. Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. J Pathol 231, 21-34 (2013).
    • (2013) J Pathol , vol.231 , pp. 21-34
    • Bashashati, A.1
  • 9
    • 84882456516 scopus 로고    scopus 로고
    • Whole exome sequence analysis of serous borderline tumors of the ovary
    • Boyd, J. et al. Whole exome sequence analysis of serous borderline tumors of the ovary. Gynecol Oncol 130, 560-564 (2013).
    • (2013) Gynecol Oncol , vol.130 , pp. 560-564
    • Boyd, J.1
  • 10
    • 79953666737 scopus 로고    scopus 로고
    • Somatic mutations of PPP2R1A in ovarian and uterine carcinomas
    • Shih Ie, M. et al. Somatic mutations of PPP2R1A in ovarian and uterine carcinomas. Am J Pathol 178, 1442-1447 (2011).
    • (2011) Am J Pathol , vol.178 , pp. 1442-1447
    • Shih Ie, M.1
  • 11
    • 70350340056 scopus 로고    scopus 로고
    • Serine/threonine phosphatases: Mechanism through structure
    • Shi, Y. Serine/threonine phosphatases: mechanism through structure. Cell 139, 468-484 (2009).
    • (2009) Cell , vol.139 , pp. 468-484
    • Shi, Y.1
  • 12
    • 34247190179 scopus 로고    scopus 로고
    • Functional interaction of Aurora-A and PP2A during mitosis
    • Horn, V. et al. Functional interaction of Aurora-A and PP2A during mitosis. Mol Biol Cell 18, 1233-1241 (2007).
    • (2007) Mol Biol Cell , vol.18 , pp. 1233-1241
    • Horn, V.1
  • 13
    • 70350540470 scopus 로고    scopus 로고
    • Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress
    • Feng, J. et al. Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress. Mol Cell Biol 29, 5696-5709 (2009).
    • (2009) Mol Cell Biol , vol.29 , pp. 5696-5709
    • Feng, J.1
  • 14
    • 84880595479 scopus 로고    scopus 로고
    • PP2A function toward mitotic kinases and substrates during the cell cycle
    • Jeong, A. L. & Yang, Y. PP2A function toward mitotic kinases and substrates during the cell cycle. BMB Rep 46, 289-294.
    • BMB Rep , vol.46 , pp. 289-294
    • Jeong, A.L.1    Yang, Y.2
  • 15
    • 84885223009 scopus 로고    scopus 로고
    • Ceramide in the prostate
    • Dent, P. Ceramide in the prostate. Cancer Biol Ther 14, 881-882 (2013).
    • (2013) Cancer Biol Ther , vol.14 , pp. 881-882
    • Dent, P.1
  • 16
    • 78049480679 scopus 로고    scopus 로고
    • Fingolimod (FTY720): Discovery and development of an oral drug to treat multiple sclerosis
    • Brinkmann, V. et al. Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis. Nat Rev Drug Discov 9, 883-897 (2010).
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 883-897
    • Brinkmann, V.1
  • 17
    • 84929414337 scopus 로고    scopus 로고
    • PP2A: The Wolf in Sheep's Clothing?
    • Kiely, M. & Kiely, P. A. PP2A: The Wolf in Sheep's Clothing? Cancers (Basel) 7, 648-669 (2015).
    • (2015) Cancers (Basel) , vol.7 , pp. 648-669
    • Kiely, M.1    Kiely, P.A.2
  • 18
    • 84891358727 scopus 로고    scopus 로고
    • Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53
    • Duong, F. H. et al. Protein phosphatase 2A promotes hepatocellular carcinogenesis in the diethylnitrosamine mouse model through inhibition of p53. Carcinogenesis 35, 114-122 (2013).
    • (2013) Carcinogenesis , vol.35 , pp. 114-122
    • Duong, F.H.1
  • 19
    • 33845367029 scopus 로고    scopus 로고
    • Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-Associated p38 mitogen-Activated protein kinase
    • Boudreau, R. T., Conrad, D. M. & Hoskin, D. W. Apoptosis induced by protein phosphatase 2A (PP2A) inhibition in T leukemia cells is negatively regulated by PP2A-Associated p38 mitogen-Activated protein kinase. Cell Signal 19, 139-151 (2007).
    • (2007) Cell Signal , vol.19 , pp. 139-151
    • Boudreau, R.T.1    Conrad, D.M.2    Hoskin, D.W.3
  • 20
    • 80755189937 scopus 로고    scopus 로고
    • Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-Terminal kinase pathway
    • Li, W. et al. Growth of the pancreatic cancer cell line PANC-1 is inhibited by protein phosphatase 2A inhibitors through overactivation of the c-Jun N-Terminal kinase pathway. Eur J Cancer 47, 2654-2664 (2011).
    • (2011) Eur J Cancer , vol.47 , pp. 2654-2664
    • Li, W.1
  • 21
    • 84855644497 scopus 로고    scopus 로고
    • Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia
    • Hofstetter, C. P. et al. Protein phosphatase 2A mediates dormancy of glioblastoma multiforme-derived tumor stem-like cells during hypoxia. PLoS One 7, e30059 (2012).
    • (2012) PLoS One , vol.7 , pp. e30059
    • Hofstetter, C.P.1
  • 22
    • 0025275038 scopus 로고
    • Alpha-And beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure
    • Hemmings, B. A. et al. alpha-And beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure. Biochemistry 29, 3166-3173 (1990).
    • (1990) Biochemistry , vol.29 , pp. 3166-3173
    • Hemmings, B.A.1
  • 23
    • 0035804217 scopus 로고    scopus 로고
    • Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene
    • Ruediger, R., Pham, H. T. & Walter, G. Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. Oncogene 20, 10-15 (2001).
    • (2001) Oncogene , vol.20 , pp. 10-15
    • Ruediger, R.1    Pham, H.T.2    Walter, G.3
  • 24
    • 0034708257 scopus 로고    scopus 로고
    • Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serinethreonine phosphatase 2A in human neoplasms
    • Calin, G. A. et al. Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serinethreonine phosphatase 2A in human neoplasms. Oncogene 19, 1191-1195 (2000).
    • (2000) Oncogene , vol.19 , pp. 1191-1195
    • Calin, G.A.1
  • 25
    • 24944485819 scopus 로고    scopus 로고
    • Cancer-Associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity
    • Chen, W., Arroyo, J. D., Timmons, J. C., Possemato, R. & Hahn, W. C. Cancer-Associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity. Cancer Res 65, 8183-8192 (2005).
    • (2005) Cancer Res , vol.65 , pp. 8183-8192
    • Chen, W.1    Arroyo, J.D.2    Timmons, J.C.3    Possemato, R.4    Hahn, W.C.5
  • 26
    • 0032500792 scopus 로고    scopus 로고
    • Alterations of the PPP2R1B gene in human lung and colon cancer
    • Wang, S. S. et al. Alterations of the PPP2R1B gene in human lung and colon cancer. Science 282, 284-287 (1998).
    • (1998) Science , vol.282 , pp. 284-287
    • Wang, S.S.1
  • 27
    • 4644344978 scopus 로고    scopus 로고
    • PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers
    • Tamaki, M., Goi, T., Hirono, Y., Katayama, K. & Yamaguchi, A. PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers. Oncol Rep 11, 655-659 (2004).
    • (2004) Oncol Rep , vol.11 , pp. 655-659
    • Tamaki, M.1    Goi, T.2    Hirono, Y.3    Katayama, K.4    Yamaguchi, A.5
  • 28
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • Jones, S. et al. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 330, 228-231 (2010).
    • (2010) Science , vol.330 , pp. 228-231
    • Jones, S.1
  • 29
    • 84864764430 scopus 로고    scopus 로고
    • Use of mutation profiles to refine the classification of endometrial carcinomas
    • McConechy, M. K. et al. Use of mutation profiles to refine the classification of endometrial carcinomas. J Pathol 228, 20-30.
    • J Pathol , vol.228 , pp. 20-30
    • McConechy, M.K.1
  • 30
    • 84877254190 scopus 로고    scopus 로고
    • Integrated genomic characterization of endometrial carcinoma
    • Kandoth, C. et al. Integrated genomic characterization of endometrial carcinoma. Nature 497, 67-73 (2013).
    • (2013) Nature , vol.497 , pp. 67-73
    • Kandoth, C.1
  • 31
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: Genes, pathways, and networks in a collection of 18, 000 cancer gene expression profiles
    • Rhodes, D. R. et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18, 000 cancer gene expression profiles. Neoplasia 9, 166-180 (2007).
    • (2007) Neoplasia , vol.9 , pp. 166-180
    • Rhodes, D.R.1
  • 32
    • 18544365698 scopus 로고    scopus 로고
    • Gene-expression profiles predict survival of patients with lung adenocarcinoma
    • Beer, D. G. et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med 8, 816-824 (2002).
    • (2002) Nat Med , vol.8 , pp. 816-824
    • Beer, D.G.1
  • 33
    • 48549092983 scopus 로고    scopus 로고
    • A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer
    • Bonome, T. et al. A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer. Cancer Res 68, 5478-5486 (2008).
    • (2008) Cancer Res , vol.68 , pp. 5478-5486
    • Bonome, T.1
  • 34
    • 2542489234 scopus 로고    scopus 로고
    • Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis
    • Lu, K. H. et al. Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res 10, 3291-3300 (2004).
    • (2004) Clin Cancer Res , vol.10 , pp. 3291-3300
    • Lu, K.H.1
  • 35
    • 68049140801 scopus 로고    scopus 로고
    • Comparison of human and rat uterine leiomyomata: Identification of a dysregulated mammalian target of rapamycin pathway
    • Crabtree, J. S. et al. Comparison of human and rat uterine leiomyomata: identification of a dysregulated mammalian target of rapamycin pathway. Cancer Res 69, 6171-6178 (2009).
    • (2009) Cancer Res , vol.69 , pp. 6171-6178
    • Crabtree, J.S.1
  • 36
    • 27144537768 scopus 로고    scopus 로고
    • Novel genes associated with malignant melanoma but not benign melanocytic lesions
    • Talantov, D. et al. Novel genes associated with malignant melanoma but not benign melanocytic lesions. Clin Cancer Res 11, 7234-7242 (2005).
    • (2005) Clin Cancer Res , vol.11 , pp. 7234-7242
    • Talantov, D.1
  • 37
    • 67449107983 scopus 로고    scopus 로고
    • A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect
    • Agnelli, L. et al. A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect. Genes Chromosomes Cancer 48, 603-614 (2009).
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 603-614
    • Agnelli, L.1
  • 38
    • 33846894934 scopus 로고    scopus 로고
    • Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis
    • Zhan, F. et al. Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis. Blood 109, 1692-1700 (2007).
    • (2007) Blood , vol.109 , pp. 1692-1700
    • Zhan, F.1
  • 39
    • 84861527388 scopus 로고    scopus 로고
    • The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups
    • Curtis, C. et al. The genomic and transcriptomic architecture of 2, 000 breast tumours reveals novel subgroups. Nature 486, 346-352 (2012).
    • (2012) Nature , vol.486 , pp. 346-352
    • Curtis, C.1
  • 40
    • 2542565666 scopus 로고    scopus 로고
    • Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification
    • Dyrskjot, L. et al. Gene expression in the urinary bladder: A common carcinoma in situ gene expression signature exists disregarding histopathological classification. Cancer Res 64, 4040-4048 (2004).
    • (2004) Cancer Res , vol.64 , pp. 4040-4048
    • Dyrskjot, L.1
  • 41
    • 0035970050 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
    • Welsh, J. B. et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc Natl Acad Sci USA 98, 1176-1181 (2001).
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1176-1181
    • Welsh, J.B.1
  • 42
    • 1542329149 scopus 로고    scopus 로고
    • Predicting biomarkers for ovarian cancer using gene-expression microarrays
    • Adib, T. R. et al. Predicting biomarkers for ovarian cancer using gene-expression microarrays. Br J Cancer 90, 686-692 (2004).
    • (2004) Br J Cancer , vol.90 , pp. 686-692
    • Adib, T.R.1
  • 43
    • 67650712196 scopus 로고    scopus 로고
    • Gene expression profiling of advanced-stage serous ovarian cancers distinguishes novel subclasses and implicates ZEB2 in tumor progression and prognosis
    • Yoshihara, K. et al. Gene expression profiling of advanced-stage serous ovarian cancers distinguishes novel subclasses and implicates ZEB2 in tumor progression and prognosis. Cancer Sci 100, 1421-1428 (2009).
    • (2009) Cancer Sci , vol.100 , pp. 1421-1428
    • Yoshihara, K.1
  • 44
    • 32944462571 scopus 로고    scopus 로고
    • Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas
    • Hendrix, N. D. et al. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Res 66, 1354-1362 (2006).
    • (2006) Cancer Res , vol.66 , pp. 1354-1362
    • Hendrix, N.D.1
  • 45
    • 0042090278 scopus 로고    scopus 로고
    • Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing
    • Javelaud, D., Laboureau, J., Gabison, E., Verrecchia, F. & Mauviel, A. Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing. J Biol Chem 278, 24624-24628 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 24624-24628
    • Javelaud, D.1    Laboureau, J.2    Gabison, E.3    Verrecchia, F.4    Mauviel, A.5
  • 46
    • 0037063314 scopus 로고    scopus 로고
    • Endothelin suppresses cell migration via the JNK signaling pathway in a manner dependent upon Src kinase, Rac1, and Cdc42
    • Yamauchi, J. et al. Endothelin suppresses cell migration via the JNK signaling pathway in a manner dependent upon Src kinase, Rac1, and Cdc42. FEBS Lett 527, 284-288 (2002).
    • (2002) FEBS Lett , vol.527 , pp. 284-288
    • Yamauchi, J.1
  • 47
    • 7244231301 scopus 로고    scopus 로고
    • MAP kinases and cell migration
    • Huang, C., Jacobson, K. & Schaller, M. D. MAP kinases and cell migration. J Cell Sci 117, 4619-4628 (2004).
    • (2004) J Cell Sci , vol.117 , pp. 4619-4628
    • Huang, C.1    Jacobson, K.2    Schaller, M.D.3
  • 48
    • 0346100572 scopus 로고    scopus 로고
    • Hepatitis C virus inhibits interferon signaling through upregulation of protein phosphatase 2A
    • Duong, F. H., Filipowicz, M., Tripodi, M., La Monica, N. & Heim, M. H. Hepatitis C virus inhibits interferon signaling through upregulation of protein phosphatase 2A. Gastroenterology 126, 263-277 (2004).
    • (2004) Gastroenterology , vol.126 , pp. 263-277
    • Duong, F.H.1    Filipowicz, M.2    Tripodi, M.3    La Monica, N.4    Heim, M.H.5
  • 49
    • 84903691855 scopus 로고    scopus 로고
    • PP2A inhibition overcomes acquired resistance to HER2 targeted therapy
    • McDermott, M. S. et al. PP2A inhibition overcomes acquired resistance to HER2 targeted therapy. Mol Cancer 13, 157 (2014).
    • (2014) Mol Cancer , vol.13 , pp. 157
    • McDermott, M.S.1
  • 50
    • 37749015044 scopus 로고    scopus 로고
    • A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC
    • Eichhorn, P. J., Creyghton, M. P., Wilhelmsen, K., van Dam, H. & Bernards, R. A RNA interference screen identifies the protein phosphatase 2A subunit PR55gamma as a stress-sensitive inhibitor of c-SRC. PLos Genet 3, e218 (2007).
    • (2007) PLos Genet , vol.3 , pp. e218
    • Eichhorn, P.J.1    Creyghton, M.P.2    Wilhelmsen, K.3    Van Dam, H.4    Bernards, R.5
  • 51
    • 84866161747 scopus 로고    scopus 로고
    • PPP2R1A mutations are common in the serous type of endometrial cancer
    • Nagendra, D. C., Burke, J., 3rd, Maxwell, G. L. & Risinger, J. I. PPP2R1A mutations are common in the serous type of endometrial cancer. Mol Carcinog 51, 826-831 (2011).
    • (2011) Mol Carcinog , vol.51 , pp. 826-831
    • Nagendra, D.C.1    Burke, J.2    Maxwell, G.L.3    Risinger, J.I.4
  • 52
    • 84890112683 scopus 로고    scopus 로고
    • Interleukin-32beta stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway
    • Park, J. S. et al. Interleukin-32beta stimulates migration of MDA-MB-231 and MCF-7cells via the VEGF-STAT3 signaling pathway. Cell Oncol (Dordr) 36, 493-503 (2013).
    • (2013) Cell Oncol (Dordr) , vol.36 , pp. 493-503
    • Park, J.S.1
  • 53
    • 84906220799 scopus 로고    scopus 로고
    • Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases
    • Lee, S., Han, S., Jeong, A. L., Park, J. S. & Yang, Y. Depletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatases. FEBS Lett 588, 2844-2850.
    • FEBS Lett , vol.588 , pp. 2844-2850
    • Lee, S.1    Han, S.2    Jeong, A.L.3    Park, J.S.4    Yang, Y.5
  • 54
    • 84891676480 scopus 로고    scopus 로고
    • Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity
    • Jeong, A. L. et al. Cancerous inhibitor of protein phosphatase 2A (CIP2A) protein is involved in centrosome separation through the regulation of NIMA (never in mitosis gene A)-related kinase 2 (NEK2) protein activity. J Biol Chem 289, 28-40 (2014).
    • (2014) J Biol Chem , vol.289 , pp. 28-40
    • Jeong, A.L.1
  • 55
    • 79952568603 scopus 로고    scopus 로고
    • Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas
    • McConechy, M. K. et al. Subtype-specific mutation of PPP2R1A in endometrial and ovarian carcinomas. J Pathol 223, 567-573 (2011).
    • (2011) J Pathol , vol.223 , pp. 567-573
    • McConechy, M.K.1
  • 56
    • 84864764430 scopus 로고    scopus 로고
    • Use of mutation profiles to refine the classification of endometrial carcinomas
    • McConechy, M. K. et al. Use of mutation profiles to refine the classification of endometrial carcinomas. J Pathol 228, 20-30 (2012).
    • (2012) J Pathol , vol.228 , pp. 20-30
    • McConechy, M.K.1


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