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Volumn 11, Issue 6, 2016, Pages

Repeated vaccination of cows with HIV env gp140 during subsequent pregnancies elicits and sustains an enduring strong env-binding and neutralising antibody response

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 140; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN G ANTIBODY; NEUTRALIZING ANTIBODY; GP140 ENVELOPE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

EID: 84976407792     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0157353     Document Type: Article
Times cited : (10)

References (49)
  • 1
    • 84922287392 scopus 로고    scopus 로고
    • Tenofovir-based preexposure prophylaxis for HIV infection among African women
    • PMID: 25651245
    • Marrazzo J.M., et al., Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med, 2015. 372(6): p. 509-18. doi: 10.1056/NEJMoa1402269 PMID: 25651245
    • (2015) N Engl J Med , vol.372 , Issue.6 , pp. 509-518
    • Marrazzo, J.M.1
  • 2
    • 84155171087 scopus 로고    scopus 로고
    • Tenofovir-based pre-exposure prophylaxis for HIV prevention: Evolving evidence
    • PMID: 22156901
    • Celum C. and Baeten J.M., Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence. Curr Opin Infect Dis, 2012. 25(1): p. 51-7. doi: 10.1097/QCO.0b013e32834ef5ef PMID: 22156901
    • (2012) Curr Opin Infect Dis , vol.25 , Issue.1 , pp. 51-57
    • Celum, C.1    Baeten, J.M.2
  • 3
    • 0037190597 scopus 로고    scopus 로고
    • Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: A randomised controlled trial
    • PMID: 12383665
    • Van Damme L., et al., Effectiveness of COL-1492, a nonoxynol-9 vaginal gel, on HIV-1 transmission in female sex workers: a randomised controlled trial. Lancet, 2002. 360(9338): p. 971-7. PMID: 12383665
    • (2002) Lancet , vol.360 , Issue.9338 , pp. 971-977
    • Van Damme, L.1
  • 4
    • 18144365830 scopus 로고    scopus 로고
    • Vitro and in vivo: The story of nonoxynol 9
    • PMID: 15851907
    • Hillier S.L., et al., In vitro and in vivo: the story of nonoxynol 9. J Acquir Immune Defic Syndr, 2005. 39 (1): p. 1-8. PMID: 15851907
    • (2005) J Acquir Immune Defic Syndr , vol.39 , Issue.1 , pp. 1-8
    • Hillier, S.L.1
  • 5
    • 0035112881 scopus 로고    scopus 로고
    • Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States
    • PMID: 11170957
    • Mayer K.H., et al., Safety and tolerability of BufferGel, a novel vaginal microbicide, in women in the United States. Clin Infect Dis, 2001. 32(3): p. 476-82. PMID: 11170957
    • (2001) Clin Infect Dis , vol.32 , Issue.3 , pp. 476-482
    • Mayer, K.H.1
  • 6
    • 78349289575 scopus 로고    scopus 로고
    • The last decade of microbicide clinical trials in Africa: From hypothesis to facts
    • PMID: 21042052
    • Ramjee G., Kamali A., and McCormack S., The last decade of microbicide clinical trials in Africa: from hypothesis to facts. AIDS, 2010. 24 Suppl 4: p. S40-9. doi: 10.1097/01.aids.0000390706.81383.f3 PMID: 21042052
    • (2010) AIDS , vol.24 , pp. S40-S49
    • Ramjee, G.1    Kamali, A.2    McCormack, S.3
  • 7
    • 77955930318 scopus 로고    scopus 로고
    • Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
    • PMID: 20643915
    • Abdool Karim, Q., et al., Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science, 2010. 329(5996): p. 1168-74. doi: 10.1126/science.1193748 PMID: 20643915
    • (2010) Science , vol.329 , Issue.5996 , pp. 1168-1174
    • Abdool Karim, Q.1
  • 8
    • 84864390255 scopus 로고    scopus 로고
    • Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 envelope with potential use in microbicides
    • PMID: 22664963
    • Kramski M., et al., Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 envelope with potential use in microbicides. Antimicrob Agents Chemother, 2012. 56(8): p. 4310-9. doi: 10.1128/AAC.00453-12 PMID: 22664963
    • (2012) Antimicrob Agents Chemother , vol.56 , Issue.8 , pp. 4310-4319
    • Kramski, M.1
  • 9
    • 0034634910 scopus 로고    scopus 로고
    • Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1
    • PMID: 11153085
    • Bures R., et al., Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1. AIDS Res Hum Retroviruses, 2000. 16(18): p. 2019-35. PMID: 11153085
    • (2000) AIDS Res Hum Retroviruses , vol.16 , Issue.18 , pp. 2019-2035
    • Bures, R.1
  • 10
    • 0032949148 scopus 로고    scopus 로고
    • Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected individuals
    • PMID: 9882391
    • BeddowsS.et al.Comparison of the antibody repertoire generated in healthy volunteers following immunization with a monomeric recombinant gp120 construct derived from a CCR5/CXCR4-using human immunodeficiency virus type 1 isolate with sera from naturally infected individualsJ Virol19997321740-1745PMID: 9882391
    • (1999) J Virol , vol.73 , Issue.2 , pp. 1740-1745
    • Beddows, S.1
  • 11
    • 77956425857 scopus 로고    scopus 로고
    • Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level
    • PMID: 20802498
    • Bunnik E.M., et al., Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level. Nat Med, 2010. 16(9): p. 995-7. doi: 10.1038/nm.2203 PMID: 20802498
    • (2010) Nat Med , vol.16 , Issue.9 , pp. 995-9597
    • Bunnik, E.M.1
  • 12
    • 69549097604 scopus 로고    scopus 로고
    • HIV-1-specific antibody responses during acute and chronic HIV-1 infection
    • PMID: 20048700
    • Tomaras G.D. and Haynes B.F., HIV-1-specific antibody responses during acute and chronic HIV-1 infection. Curr Opin HIV AIDS, 2009. 4(5): p. 373-9. doi: 10.1097/COH.0b013e32832f00c0 PMID: 20048700
    • (2009) Curr Opin HIV AIDS , vol.4 , Issue.5 , pp. 373-379
    • Tomaras, G.D.1    Haynes, B.F.2
  • 13
    • 84864296663 scopus 로고    scopus 로고
    • Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
    • PMID: 22641382
    • McCoy L.E., et al., Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization. J Exp Med, 2012. 209(6): p. 1091-103. doi: 10.1084/jem.20112655 PMID: 22641382
    • (2012) J Exp Med , vol.209 , Issue.6 , pp. 1091-1103
    • McCoy, L.E.1
  • 14
    • 84867198866 scopus 로고    scopus 로고
    • Anti-HIV-1 antibody-dependent cellular cytotoxicity mediated by hyperimmune bovine colostrum IgG
    • PMID: 22730083
    • Kramski M., et al., Anti-HIV-1 antibody-dependent cellular cytotoxicity mediated by hyperimmune bovine colostrum IgG. Eur J Immunol, 2012. 42(10): p. 2771-81. doi: 10.1002/eji.201242469 PMID: 22730083
    • (2012) Eur J Immunol , vol.42 , Issue.10 , pp. 2771-2781
    • Kramski, M.1
  • 15
    • 70350564956 scopus 로고    scopus 로고
    • Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens
    • PMID: 19712773
    • Center R.J., et al., Induction of HIV-1 subtype B and AE-specific neutralizing antibodies in mice and macaques with DNA prime and recombinant gp140 protein boost regimens. Vaccine, 2009. 27(47): p. 6605-12. doi: 10.1016/j.vaccine.2009.08.016 PMID: 19712773
    • (2009) Vaccine , vol.27 , Issue.47 , pp. 6605-16012
    • Center, R.J.1
  • 16
    • 77954920017 scopus 로고    scopus 로고
    • Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
    • PMID: 20616233
    • Wu X., et al., Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science, 2010. 329(5993): p. 856-61. doi: 10.1126/science.1187659 PMID: 20616233
    • (2010) Science , vol.329 , Issue.5993 , pp. 856-861
    • Wu, X.1
  • 17
    • 84863769888 scopus 로고    scopus 로고
    • The development of CD4 binding site antibodies during HIV-1 infection
    • PMID: 22573869
    • Lynch R.M., et al., The development of CD4 binding site antibodies during HIV-1 infection. J Virol, 2012. 86(14): p. 7588-95. doi: 10.1128/JVI.00734-12 PMID: 22573869
    • (2012) J Virol , vol.86 , Issue.14 , pp. 7588-7595
    • Lynch, R.M.1
  • 18
    • 84866172362 scopus 로고    scopus 로고
    • Neutralizing antibody escape during HIV-1 mother-to-child transmission involves conformational masking of distal epitopes in envelope
    • PMID: 22740394
    • Goo L., et al., Neutralizing antibody escape during HIV-1 mother-to-child transmission involves conformational masking of distal epitopes in envelope. J Virol, 2012. 86(18): p. 9566-82. doi: 10.1128/JVI. 00953-12 PMID: 22740394
    • (2012) J Virol , vol.86 , Issue.18 , pp. 9566-9582
    • Goo, L.1
  • 19
    • 0025042354 scopus 로고
    • Importance of hypervariable regions of HIV-1 gp120 in the generation of virus neutralizing antibodies
    • PMID: 2390335
    • Haigwood N.L., et al., Importance of hypervariable regions of HIV-1 gp120 in the generation of virus neutralizing antibodies. AIDS Res Hum Retroviruses, 1990. 6(7): p. 855-69. PMID: 2390335
    • (1990) AIDS Res Hum Retroviruses , vol.6 , Issue.7 , pp. 855-869
    • Haigwood, N.L.1
  • 20
    • 0024573698 scopus 로고
    • Isolate- and group-specific immune responses to the envelope protein of human immunodeficiency virus induced by a live recombinant vaccinia virus in macaques
    • PMID: 2541747
    • Earl P.L., et al., Isolate- and group-specific immune responses to the envelope protein of human immunodeficiency virus induced by a live recombinant vaccinia virus in macaques. AIDS Res Hum Retroviruses, 1989. 5(1): p. 23-32. PMID: 2541747
    • (1989) AIDS Res Hum Retroviruses , vol.5 , Issue.1 , pp. 23-32
    • Earl, P.L.1
  • 21
    • 73949084963 scopus 로고    scopus 로고
    • Breadth of human immunodeficiency virus-specific neutralizing activity in sera: Clustering analysis and association with clinical variables
    • PMID: 19923174
    • Doria-Rose N.A., et al., Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables. J Virol, 2010. 84(3): p. 1631-6. doi: 10.1128/ JVI.01482-09 PMID: 19923174
    • (2010) J Virol , vol.84 , Issue.3 , pp. 1631-1636
    • Doria-Rose, N.A.1
  • 22
    • 69249208675 scopus 로고    scopus 로고
    • Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors
    • PMID: 19553335
    • Gray E.S., et al., Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors. J Virol, 2009. 83(17): p. 8925-37. doi: 10.1128/JVI.00758-09 PMID: 19553335
    • (2009) J Virol , vol.83 , Issue.17 , pp. 8925-8937
    • Gray, E.S.1
  • 23
    • 58149399396 scopus 로고    scopus 로고
    • Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies
    • PMID: 18922865
    • Doria-Rose N.A., et al., Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies. J Virol, 2009. 83(1): p. 188-99. doi: 10. 1128/JVI.01583-08 PMID: 18922865
    • (2009) J Virol , vol.83 , Issue.1 , pp. 188-199
    • Doria-Rose, N.A.1
  • 24
    • 56449131391 scopus 로고    scopus 로고
    • Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C
    • PMID: 18815292
    • Binley J.M., et al., Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C. J Virol, 2008. 82(23): p. 11651-68. doi: 10.1128/JVI.01762-08 PMID: 18815292
    • (2008) J Virol , vol.82 , Issue.23 , pp. 11651-11668
    • Binley, J.M.1
  • 25
    • 58149487646 scopus 로고    scopus 로고
    • Continuous viral escape and selection by autologous neutralizing antibodies in drug-naive human immunodeficiency virus controllers
    • PMID: 18987151
    • Mahalanabis M., et al., Continuous viral escape and selection by autologous neutralizing antibodies in drug-naive human immunodeficiency virus controllers. J Virol, 2009. 83(2): p. 662-72. doi: 10.1128/ JVI.01328-08 PMID: 18987151
    • (2009) J Virol , vol.83 , Issue.2 , pp. 662-672
    • Mahalanabis, M.1
  • 26
    • 35348937119 scopus 로고    scopus 로고
    • Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies
    • PMID: 17632196
    • Rademeyer C., et al., Genetic characteristics of HIV-1 subtype C envelopes inducing cross-neutralizing antibodies. Virology, 2007. 368(1): p. 172-81. PMID: 17632196
    • (2007) Virology , vol.368 , Issue.1 , pp. 172-181
    • Rademeyer, C.1
  • 27
    • 33144486096 scopus 로고    scopus 로고
    • Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1
    • PMID: 16474158
    • Moore P.L., et al., Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1. J Virol, 2006. 80(5): p. 2515-28. PMID: 16474158
    • (2006) J Virol , vol.80 , Issue.5 , pp. 2515-2528
    • Moore, P.L.1
  • 28
    • 0037213278 scopus 로고    scopus 로고
    • Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies
    • PMID: 12477840
    • Poignard P., et al., Heterogeneity of envelope molecules expressed on primary human immunodeficiency virus type 1 particles as probed by the binding of neutralizing and nonneutralizing antibodies. J Virol, 2003. 77(1): p. 353-65. PMID: 12477840
    • (2003) J Virol , vol.77 , Issue.1 , pp. 353-365
    • Poignard, P.1
  • 29
    • 84899991983 scopus 로고    scopus 로고
    • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies
    • PMID: 24590074
    • Doria-Rose N.A., et al., Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 2014. 509(7498): p. 55-62. doi: 10.1038/nature13036 PMID: 24590074
    • (2014) Nature , vol.509 , Issue.7498 , pp. 55-62
    • Doria-Rose, N.A.1
  • 30
    • 84866443327 scopus 로고    scopus 로고
    • Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
    • PMID: 22826297
    • Klein F., et al., Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. J Exp Med, 2012. 209(8): p. 1469-79. doi: 10.1084/jem.20120423 PMID: 22826297
    • (2012) J Exp Med , vol.209 , Issue.8 , pp. 1469-1479
    • Klein, F.1
  • 31
    • 70349887757 scopus 로고    scopus 로고
    • Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
    • PMID: 19729618
    • Walker L.M., et al., Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science, 2009. 326(5950): p. 285-9. doi: 10.1126/science.1178746 PMID: 19729618
    • (2009) Science , vol.326 , Issue.5950 , pp. 285-289
    • Walker, L.M.1
  • 32
    • 84864365540 scopus 로고    scopus 로고
    • HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120
    • PMID: 22773820
    • Kovacs J.M., et al., HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120. Proc Natl Acad Sci U S A, 2012. 109(30): p. 12111-6. doi: 10.1073/pnas.1204533109 PMID: 22773820
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.30 , pp. 12111-12116
    • Kovacs, J.M.1
  • 33
    • 34547154404 scopus 로고    scopus 로고
    • Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization
    • PMID: 17540729
    • Zhang P.F., et al., Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization. Proc Natl Acad Sci U S A, 2007. 104(24): p. 10193-8. PMID: 17540729
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.24 , pp. 10193-10198
    • Zhang, P.F.1
  • 34
    • 27744503475 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization
    • PMID: 16282480
    • Hammonds J., et al., Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization. J Virol, 2005. 79(23): p. 14804-14. PMID: 16282480
    • (2005) J Virol , vol.79 , Issue.23 , pp. 14804-14814
    • Hammonds, J.1
  • 35
    • 4444342579 scopus 로고    scopus 로고
    • Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d
    • PMID: 15078953
    • Bower J.F., et al., Elicitation of neutralizing antibodies with DNA vaccines expressing soluble stabilized human immunodeficiency virus type 1 envelope glycoprotein trimers conjugated to C3d. J Virol, 2004. 78(9): p. 4710-9. PMID: 15078953
    • (2004) J Virol , vol.78 , Issue.9 , pp. 4710-4719
    • Bower, J.F.1
  • 36
    • 0036231093 scopus 로고    scopus 로고
    • Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin
    • PMID: 11932429
    • Yang X., et al., Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin. J Virol, 2002. 76(9): p. 4634-42. PMID: 11932429
    • (2002) J Virol , vol.76 , Issue.9 , pp. 4634-4642
    • Yang, X.1
  • 37
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • PMID: 19843557
    • Rerks-Ngarm S., et al., Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med, 2009. 361(23): p. 2209-20. doi: 10.1056/NEJMoa0908492 PMID: 19843557
    • (2009) N Engl J Med , vol.361 , Issue.23 , pp. 2209-2220
    • Rerks-Ngarm, S.1
  • 38
    • 84859393693 scopus 로고    scopus 로고
    • Immune-correlates analysis of an HIV-1 vaccine efficacy trial
    • PMID: 22475592
    • Haynes B.F., et al., Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med, 2012. 366(14): p. 1275-86. doi: 10.1056/NEJMoa1113425 PMID: 22475592
    • (2012) N Engl J Med , vol.366 , Issue.14 , pp. 1275-1286
    • Haynes, B.F.1
  • 39
    • 84872809067 scopus 로고    scopus 로고
    • Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2
    • PMID: 23313589
    • Liao H.X., et al., Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2. Immunity, 2013. 38(1): p. 176-86. doi: 10.1016/j.immuni.2012.11.011 PMID: 23313589
    • (2013) Immunity , vol.38 , Issue.1 , pp. 176-186
    • Liao, H.X.1
  • 40
    • 84909640954 scopus 로고    scopus 로고
    • Structure and immune recognition of trimeric pre-fusion HIV-1 Env
    • PMID: 25296255
    • Pancera M., et al., Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature, 2014. 514(7523): p. 455-61. doi: 10.1038/nature13808 PMID: 25296255
    • (2014) Nature , vol.514 , Issue.7523 , pp. 455-461
    • Pancera, M.1
  • 41
    • 84903173697 scopus 로고    scopus 로고
    • Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
    • PMID: 24884783
    • Yasmeen A., et al., Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits. Retrovirology, 2014. 11: p. 41. doi: 10.1186/1742-4690-11-41 PMID: 24884783
    • (2014) Retrovirology , vol.11 , pp. 41
    • Yasmeen, A.1
  • 42
    • 84890858459 scopus 로고    scopus 로고
    • Crystal structure of a soluble cleaved HIV-1 envelope trimer
    • PMID: 24179159
    • Julien J.P., et al., Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science, 2013. 342 (6165): p. 1477-83. doi: 10.1126/science.1245625 PMID: 24179159
    • (2013) Science , vol.342 , Issue.6165 , pp. 1477-1483
    • Julien, J.P.1
  • 43
    • 84887307095 scopus 로고    scopus 로고
    • Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
    • PMID: 24145402
    • Ringe R.P., et al., Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation. Proc Natl Acad Sci U S A, 2013. 110(45): p. 18256-61. doi: 10.1073/ pnas.1314351110 PMID: 24145402
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.45 , pp. 18256-18261
    • Ringe, R.P.1
  • 44
    • 84940192994 scopus 로고    scopus 로고
    • HIV-1 VACCINES Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies
    • Williams W.B., et al., HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science, 2015. 349((6249).
    • (2015) Science , vol.349 , Issue.6249
    • Williams, W.B.1
  • 45
    • 26044461491 scopus 로고    scopus 로고
    • The bovine antibody repertoire
    • PMID: 16054212
    • Zhao Y., Jackson S.M., and Aitken R., The bovine antibody repertoire. Dev Comp Immunol, 2006. 30 (1-2): p. 175-86. PMID: 16054212
    • (2006) Dev Comp Immunol , vol.30 , Issue.1-2 , pp. 175-186
    • Zhao, Y.1    Jackson, S.M.2    Aitken, R.3
  • 46
    • 0031572510 scopus 로고    scopus 로고
    • Bovine IgG repertoire is dominated by a single diversified VH gene family
    • PMID: 9378976
    • Sinclair M.C., Gilchrist J., and Aitken R., Bovine IgG repertoire is dominated by a single diversified VH gene family. J Immunol, 1997. 159(8): p. 3883-9. PMID: 9378976
    • (1997) J Immunol , vol.159 , Issue.8 , pp. 3883-3889
    • Sinclair, M.C.1    Gilchrist, J.2    Aitken, R.3
  • 47
    • 33847101745 scopus 로고    scopus 로고
    • Structural definition of a conserved neutralization epitope on HIV-1 gp120
    • PMID: 17301785
    • Zhou T., et al., Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature, 2007. 445(7129): p. 732-7. PMID: 17301785
    • (2007) Nature , vol.445 , Issue.7129 , pp. 732-737
    • Zhou, T.1
  • 48
    • 0037227422 scopus 로고    scopus 로고
    • Analysis of the antigen combining site: Correlations between length and sequence composition of the hypervariable loops and the nature of the antigen
    • PMID: 12488099
    • Collis A.V., Brouwer A.P., and Martin A.C., Analysis of the antigen combining site: correlations between length and sequence composition of the hypervariable loops and the nature of the antigen. J Mol Biol, 2003. 325(2): p. 337-54. PMID: 12488099
    • (2003) J Mol Biol , vol.325 , Issue.2 , pp. 337-354
    • Collis, A.V.1    Brouwer, A.P.2    Martin, A.C.3
  • 49
    • 57749192917 scopus 로고    scopus 로고
    • Somatic hypermutations and isotype restricted exceptionally long CDR3H contribute to antibody diversification in cattle
    • PMID: 19012969
    • Kaushik A.K., et al., Somatic hypermutations and isotype restricted exceptionally long CDR3H contribute to antibody diversification in cattle. Vet Immunol Immunopathol, 2009. 127(1-2): p. 106-13. doi: 10.1016/j.vetimm.2008.09.024 PMID: 19012969
    • (2009) Vet Immunol Immunopathol , vol.127 , Issue.1-2 , pp. 106-113
    • Kaushik, A.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.