Association between placental lesions, cytokines and angiogenic factors in pregnant women with preeclampsia

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Weel, Ingrid C ^a   Baergen, Rebecca N ^b   Romão Veiga, Mariana ^a   Borges, Vera T ^a   Ribeiro, Vanessa R ^a   Witkin, Steven S ^c   Bannwart Castro, Camila ^a   Peraçoli, Jose C ^a   De Oliveira, Leandro ^a   Peraçoli, Maria T ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENIC FACTOR; CYTOKINE; ENDOGLIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; PLACENTAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; FLT1 PROTEIN, HUMAN; IL10 PROTEIN, HUMAN; PGF PROTEIN, HUMAN; TUMOR NECROSIS FACTOR; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBRIN DEPOSITION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PLACENTA DISORDER; PREECLAMPSIA; PREGNANT WOMAN; METABOLISM; ONSET AGE; PATHOLOGY; PLACENTA; PREGNANCY;

ADULT; AGE OF ONSET; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-10; PLACENTA; PLACENTA GROWTH FACTOR; PRE-ECLAMPSIA; PREGNANCY; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 84976311700     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0157584     Document Type: Article

References (47)

1. Kane SC, Da Silva Costa F, Brennecke SP. New directions in the prediction of pre-eclampsia. Aust N Z J Obstet Gynaecol 2014; 54:101-107. doi: 10.1111/ajo.12151 PMID: 24358966
2. Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science 2005; 308:1592-1594. PMID: 15947178
3. ACOG Practice Bulletin no. 33. Diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol 2002; 99:159-167. PMID: 16175681
4. Huppertz B. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 2008; 51:970-975. doi: 10.1161/HYPERTENSIONAHA.107.107607 PMID: 18259009
5. van der Merwe JLVD, Hall DR, Wright C, Schubert P, Grové D. Are early and late preeclampsia distinct subclasses of the disease-what does the placenta reveal? Hypertens Pregnancy 2010; 29:457-467. doi: 10.3109/10641950903572282 PMID: 20701467
6. Ogge G, Chaiworapongsa T, Romero R, Hussein Y, Kusanovic JP, Yeo L, et al. Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia. J Perinat Med 2011; 39:641-652. doi: 10.1515/JPM.2011.098 PMID: 21848483
7. Kovo M, Schreiber L, Ben-Haroush A, Gold E, Golan A, Bar J. The placental component in early-onset and late-onset preeclampsia in relation to fetal growth restriction. Prenat Diagn 2012; 32:632-637. doi: 10.1002/pd.3872 PMID: 22565848
8. Raymond D, Peterson E. A critical review of early-onset and late-onset preeclampsia. Obstet Gynecol Surv 2011; 66:497-506. doi: 10.1097/OGX.0b013e3182331028 PMID: 22018452
9. George EM, Granger JP. Mechanisms and potential therapies for preeclampsia. Curr Hypertens Rep 2011; 13:269-275. doi: 10.1007/s11906-011-0204-0 PMID: 21465139
10. Devisme L, Merlot B, Ego A, Houfflin-Debarge V, Deruelle P, Subtil D. A case-control study of placental lesions associated with pre-eclampsia. Int J Gynaecol Obstet 2013; 120:165-168. doi: 10.1016/j.ijgo. 2012.08.023 PMID: 23200099
11. Souza DA, Bezerra AFS, Wanderley DC, Souto CMB. Increase in perivillous fibrinoid material in placentas from pregnancies with preeclampsia. J Bras Patol Med Lab 2011; 47:71-77.
12. Vinnars MT, Nasiell J, Ghazi SAM, Westgren M, Papadogiannakis N. The severity of clinical manifestations in preeclampsia correlates with the amount of placental infarction. Acta Obstet Gynecol Scand 2011; 90:19-25. doi: 10.1111/j.1600-0412.2010.01012.x PMID: 21275911
13. Stark MW, Clark L, Craver RD. Histologic differences in placentas of preeclamptic/eclamptic gestations by birthweight, placental weight, and time of onset. Pediatr Dev Pathol 2014; 17:181-189. doi: 10.2350/ 13-09-1378-OA.1 PMID: 24625285
14. Loukeris K, Sela R, Baergen RN. Syncytial knots as a reflection of placental maturity: reference values for 20 to 40 weeks' gestational age. Pediatr Dev Pathol 2010; 13:305-309. doi: 10.2350/09-08-0692-OA.1 PMID: 20017638
15. Raghupathy R. Cytokines as key players in the pathophysiology of preeclampsia. Med Princ Pract 2013; 22(suppl 1):8-19. doi: 10.1159/000354200 PMID: 23949305
16. Hung TH, Charnock-Jones DS, Skepper JN, Burton GJ. Secretion of tumor necrosis factor-alpha from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia. Am J Pathol 2004; 164:1049-1061.PMID: 14982858
17. Hayashi M, Hamada Y, Ohkura T. Elevation of granulocyte-macrophage colony-stimulating factor in the placenta and blood in preeclampsia. Am J Obstet Gynecol 2004; 190:456-461. PMID: 14981389
18. Hennessy A, Pilmore HL, Simmons LA, Painter DM. A deficiency of placental IL-10 in preeclampsia. J Immunol 1999; 163:3491-3495. PMID: 10477622
19. Makris A, Xu B, Yu B, Thornton C, Hennessy A. Placental deficiency of interleukin-10 (IL-10) in preeclampsia and its relationship to an IL10 promoter polymorphism. Placenta 2006; 27:445-451. PMID: 16026832
20. Pratt A, Da Silva Costa F, Borg AJ, Kalionis B, Keogh R, Murthi P. Placenta-derived angiogenic proteins and their contribution to the pathogenesis of preeclampsia. Angiogenesis 2015; 18:115-123. doi: 10.1007/s10456-014-9452-3 PMID: 25433512
21. Maynard S, Epstein FH, Karumanchi SA. Preeclampsia and angiogenic imbalance. Annu Rev Med 2008; 59:61-78. PMID: 17937587
22. Silasi M, Cohen B, Karumanchi SA, Rana S. Abnormal placentation, angiogenic factors, and the pathogenesis of preeclampsia. Obstet Gynecol Clin North Am 2010; 37:239-253. doi: 10.1016/j.ogc.2010. 02.013 PMID: 20685551
23. Nagy JA, Dvorak AM, Dvorak HF. VEGF-A(164/165) and PlGF: roles in angiogenesis and arteriogenesis. Trends Cardiovasc Med 2003; 13:169-175. PMID: 12837578
24. Tsatsaris V, Goffin F, Munaut C, Brichant JF, Pignon MR, Noel A, et al. Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences. J Clin Endocrinol Metab 2003; 88:5555-5563. PMID: 14602804
25. Maynard SE, Min JY, Merchan J, Lim KH, Li J, Mondal S, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertens ion, and proteinuria. J Clin Invest 2003; 111:649-658. PMID: 12618519
26. De Oliveira LG, Peraçoli JC, Peraçoli MTS, Korkes H, Zampieri G, Moron AF, et al. sFlt-1/PlGF ratio as a prognostic marker of adverse outcomes in women with early-onset preeclampsia. Pregnancy Hypertens 2013; 3:191-195. doi: 10.1016/j.preghy.2013.02.003 PMID: 26106033
27. Venkatesha S, Toporsian M, Lam C, Hanai J, Mammoto T, Kim YM, et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 2006; 12:642-649. PMID: 16751767
28. Kaplan C, Lowell DM, Salafia C. College of American Pathologists Conference XIX on the examination of the placenta: report of the working group on the definition of structural changes associated with abnormal function in the maternal/fetal/placental unit in the second and third trimesters. Arch Pathol Lab Med 1991; 115:709-716. PMID: 2064532
29. Sikkema JM, Franx A, Bruinse HW, van der Wijk NG, de Valk HW, Nikkels PG. Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia. Placenta 2002; 23:337-342. PMID: 11969345
30. Heazell AE, Moll SJ, Jones CJ, Baker PN, Crocker IP. Formation of syncytial knots is increased by hyperoxia, hypoxia and reactive oxygen species. Placenta 2007; 28(Suppl A):S33-S40. PMID: 17140657
31. Sankar KD, Bhanu PS, Kiran S, Ramakrishna BA, Shanthi V. Vasculosyncytial membrane in relation to syncytial knots complicates the placenta in preeclampsia: a histomorphometrical study. Anat Cell Biol 2012; 45:86-91. doi: 10.5115/acb.2012.45.2.86 PMID: 22822462
32. Guller S, Ma YY, Fu HH, Krikun G, Abrahams VM, Mor G. The placental syncytium and the pathophysiology of preeclampsia and intrauterine growth restriction: a novel assay to assess syncytial protein expression. Ann N Y Acad Sci. 2008; 1127:129-133. doi: 10.1196/annals.1434.015 PMID: 18443340
33. Redman CW. Preeclampsia: a multi-stress disorder. Rev Med Interne 2011; 32 (Suppl 1): S41-S44.doi: 10.1016/j.revmed.2011.03.331 PMID: 21530020
34. Feng C, Tao Y, Shang T, Yu M. Calprotectin, RAGE and TNF-α in hypertensive disorders in pregnancy: expression and significance. Arch Gynecol Obstet 2011; 283:161-166. doi: 10.1007/s00404-009-1303-x PMID: 19953259
35. Zhou P, Luo X, Qi HB, Zong WJ, Zhang H, Liu DD, et al. The expression of pentraxin 3 and tumor necrosis factor-alpha is increased in preeclamptic placental tissue and maternal serum. Inflamm Res 2012; 61:1005-1012. doi: 10.1007/s00011-012-0507-x PMID: 22714118
36. Peraçoli JC, Bannwart-Castro CF, Romao M, Weel IC, Ribeiro VR, Borges VT, et al. High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from lateonset preeclampsia. J Reprod Immunol 2013; 100:129-134. doi: 10.1016/j.jri.2013.08.003 PMID: 24051131
37. Cristofalo R, Bannwart-Castro CF, Magalhães CG, Borges VT, Peraçoli JC, Witkin SS, et al. Silibinin attenuates oxidative metabolism and cytokine production by monocytes from preeclamptic women. Free Radic Res 2013; 47:268-275. doi: 10.3109/10715762.2013.765951 PMID: 23316804
38. Wang Y, Zhang X, Cheng GM, Ren CC. Expression of transforming growth factor-beta 1, vascular cell adhesion molecule-1 and endothelium-selectin in placenta of patients with pre-eclampsia. Zhonghua Fu Chan KeZaZhi 2006; 41:514-517.
39. Tripathi R, Rath G, Jain A, Salhan S. Soluble and membranous vascular endothelial growth factor receptor-1 in pregnancies complicated by pre-eclampsia. Ann Anat 2008; 190:477-489. doi: 10.1016/j. aanat.2008.08.002 PMID: 18992679
40. Weed S, Bastek JA, Anton L, Elovitz MA, Parry S, Srinivas SK. Examining the correlation between placental and serum placenta growth factor in preeclampsia. Am J Obstet Gynecol 2012; 207:140.e1-6.
41. Kim SC, Park MJ, Joo BS, Joo JK, Suh DS, Lee KS. Decreased expressions of vascular endothelial growth factor and visfatin in the placental bed of pregnancies complicated by preeclampsia. J Obstet Gynaecol Res 2012; 38:665-673. doi: 10.1111/j.1447-0756.2011.01773.x PMID: 22380724
42. Gu Y, Lewis DF, Wang Y. Placental productions and expressions of soluble endoglin, soluble fms-like tyrosine kinase receptor-1, and placental growth factor in normal and preeclamptic pregnancies. J Clin Endocrinol Metab 2008; 93:260-266. PMID: 17956952
43. Nevo O, Soleymanlou N, Wu Y, Xu J, Kingdom J, Many A, et al. Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am J Physiol Regul Integr Comp Physiol. 2006; 291:R1085-93. PMID: 16627691
44. Redman CW, Tannetta DS, Dragovic RA, Gardiner C, Southcombe JH, Collett GP, et al. Review: Does size matter? Placental debris and the pathophysiology of pre-eclampsia. Placenta 2012; 33 Suppl: S48-54. doi: 10.1016/j.placenta.2011.12.006 PMID: 22217911
45. Levine RJ, Maynard SE, Qian C, Lim KH, England LJ, Yu KF, et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004; 350:672-683. PMID: 14764923
46. Baltajian K, Hecht JL, Wenger JB, Salahuddin S, Verlohren S, Perschel FH, et al. Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia. Hypertension 2014; 33:427-439.
47. Rajakumar A, Cerdeira AS, Rana S, Zsengeller Z, Edmunds L, Jeyabalan A, et al. Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia. Hypertension 2012; 59:256-264. doi: 10.1161/ HYPERTENSIONAHA.111.182170 PMID: 22215706