Three-dimensional mapping and regulation of action potential propagation in nanoelectronics-innervated tissues

Nature Nanotechnology

Volumn 11, Issue 9, 2016, Pages 776-782

  Dai, Xiaochuan ^a   Zhou, Wei ^a   Gao, Teng ^a   Liu, Jia ^a   Lieber, Charles M ^a,b  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROPHYSIOLOGY; HISTOLOGY; MAPPING; NANOELECTRONICS; SCAFFOLDS (BIOLOGY); TOPOLOGY;

ACTION POTENTIAL PROPAGATION; DISEASE MODELING; EXTRACELLULAR ACTION POTENTIAL; REAL-TIME MAPPING; TEMPORAL RESOLUTION; THREE DIMENSIONAL MAPPING; THREEDIMENSIONAL (3-D); TISSUE SCAFFOLDS;

TISSUE;

HEPTANOL; NANOWIRE; NORADRENALIN; SILICON;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CONDUCTANCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENGINEERED HEART TISSUE; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART DEVELOPMENT; HEART FAILURE; HEART VENTRICLE ARRHYTHMIA; LATENT PERIOD; MOLECULAR ELECTRONICS; NANOELECTRONICS INNERVATED TISSUE; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SARCOMERE LENGTH; SENSOR; STEADY STATE; STIMULATION; SUDDEN CARDIAC DEATH; THREE DIMENSIONAL IMAGING; THREE DIMENSIONAL MAPPING; TISSUE SCAFFOLD; WAVEFORM; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CELL CULTURE TECHNIQUE; CHEMISTRY; CYTOLOGY; HEART ELECTROPHYSIOLOGY; HEART VENTRICLE; MICROELECTRODE; NANOTECHNOLOGY; PHYSIOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; CARDIAC ELECTROPHYSIOLOGY; CELL CULTURE TECHNIQUES; CELLS, CULTURED; HEART VENTRICLES; MICROELECTRODES; MODELS, CARDIOVASCULAR; NANOTECHNOLOGY; RATS; RATS, SPRAGUE-DAWLEY; TISSUE SCAFFOLDS;

EID: 84976272619     PISSN: 17483387     EISSN: 17483395     Source Type: Journal    
DOI: 10.1038/nnano.2016.96     Document Type: Article

References (39)

1. Langer, R. & Vacanti, J. P. Tissue engineering. Science 260, 920-926 (1993).
2. Eschenhagen, T. & Zimmermann, W. H. Engineering myocardial tissue. Circ. Res. 97, 1220-1231 (2005).
3. Shimizu, T. et al. Fabrication of pulsatile cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature-responsive cell culture surfaces. Circ. Res. 90, e40 (2002).
4. Dvir, T., Timko, B. P., Kohane, D. S. & Langer, R. Nanotechnological strategies for engineering complex tissues. Nature Nanotech. 6, 13-22 (2011).
5. Papadaki, M. et al. Tissue engineering of functional cardiac muscle: molecular, structural, and electrophysiological studies. Am. J. Physiol. Heart Circ. Physiol. 280, 168-178 (2001).
6. Hansen, A. et al. Development of a drug screening platform based on engineered heart tissue. Circ. Res. 107, 35-44 (2010).
7. Grosberg, A., Alford, P. W., McCain, M. L. & Parker, K. K. Ensembles of engineered cardiac tissues for physiological and pharmacological study: heart on a chip. Lab Chip 11, 4165-4173 (2011).
8. Natarajan, A. et al. Patterned cardiomyocytes on microelectrode arrays as a functional, high information content drug screening platform. Biomaterials 32, 4267-4274 (2011).
9. Griffith, L. G. & Naughton, G. Tissue engineering-current challenges and expanding opportunities. Science 295, 1009-1014 (2002).
10. Furuta, A. et al. Pulsatile cardiac tissue grafts using a novel three-dimensional cell sheet manipulation technique functionally integrates with the host heart, in vivo. Circ. Res. 98, 705-712 (2006).
11. Zimmermann, W. H. et al. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nature Med. 12, 452-458 (2006).
12. St-Pierre, F. et al. High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor. Nature Neurosci. 17, 884-889 (2014).
13. Herron, T. J., Lee, P. & Jalife, J. Optical imaging of voltage and calcium in cardiac cells & tissues. Circ. Res. 110, 609-623 (2012).
14. Kralj, J. M., Douglass, A. D., Hochbaum, D. R., Maclaurin, D. & Cohen, A. E. Optical recording of action potentials in mammalian neurons using a microbial rhodopsin. Nat. Methods 9, 90-95 (2012).
15. Huisken, J., Swoger, J., Del Bene, F., Wittbrodt, J. & Stelzer, E. H. K. Optical sectioning deep inside live embryos by selective plane illumination microscopy. Science 305, 1007-1009 (2004).
16. Kim, D. H. et al. Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy. Nature Mater. 10, 316-323 (2011).
17. Cohen-Karni, T., Timko, B. P., Weiss, L. E. & Lieber, C. M. Flexible electrical recording from cells using nanowire transistor arrays. Proc. Natl Acad. Sci. USA 106, 7309-7313 (2009).
18. Viventi, J. et al. A conformal, bio-interfaced class of silicon electronics for mapping cardiac electrophysiology. Sci. Transl. Med. 2, 24ra22 (2010).
19. Tian, B. Z. et al. Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nature Mater. 11, 986-994 (2012).
20. Place, E. S., George, J. H., Williams, C. K. & Stevens, M. M. Synthetic polymer scaffolds for tissue engineering. Chem. Soc. Rev. 38, 1139-1151 (2009).
21. Zhang, D. et al. Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials 34, 5813-5820 (2013).
22. Yelbuz, T. M., Choma, M. A., Thrane, L., Kirby, M. L. & Izatt, J. A. Optical coherence tomography - a new high-resolution imaging technology to study cardiac development in chick embryos. Circulation 106, 2771-2774 (2002).
23. Miragoli, M., Gaudesius, G. & Rohr, S. Electrotonic modulation of cardiac impulse conduction by myofibroblasts. Circ. Res. 98, 801-810 (2006).
24. Khademhosseini, A. et al. Microfluidic patterning for fabrication of contractile cardiac organoids. Biomed. Microdev. 9, 149-157 (2007).
25. Timko, B. P., Cohen-Karni, T., Qing, Q., Tian, B. & Lieber, C. M. Design and implementation of functional nanoelectronic interfaces with biomolecules, cells, and tissue using nanowire device arrays. IEEE Trans. Nanotechnol. 9, 269-280 (2010).
26. Zhang, J. H. et al. Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ. Res. 104, e30 (2009).
27. Laflamme, M. A. et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nature Biotechnol. 25, 1015-1024 (2007).
28. Myles, R. C., Wang, L. G., Kang, C. Y., Bers, D. M. & Ripplinger, C. M. Local beta-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia. Circ. Res. 110, 1454-1464 (2012).
29. Iravanian, S. et al. Functional reentry in cultured monolayers of neonatal rat cardiac cells. Am. J. Physiol. Heart Circ. Physiol. 285, 449-456 (2003).
30. Liu, J. et al. Syringe-injectable electronics. Nature Nanotech. 10, 629-636 (2015).
31. Garbern, J. C. & Lee, R. T. Cardiac stem cell therapy and the promise of heart regeneration. Cell Stem Cell 12, 689-698 (2013).
32. Wobma, H. & Vunjak-Novakovic, G. Tissue engineering and regenerative medicine 2015: a year in review. Tissue Eng. Part B Rev. 22, 101-113 (2016).
33. Wong, A. D. et al. The blood-brain barrier: an engineering perspective. Front. Neuroeng. 6, 7 (2013).
34. Wang, X. Y. et al. Engineering interconnected 3D vascular networks in hydrogels using molded sodium alginate lattice as the sacrificial template. Lab Chip 14, 2709-2716 (2014).
35. McAlpine, M. C., Ahmad, H., Wang, D. W. & Heath, J. R. Highly ordered nanowire arrays on plastic substrates for ultrasensitive flexible chemical sensors. Nature Mater. 6, 379-384 (2007).
36. Annabi, N. et al. Hydrogel-coated microfluidic channels for cardiomyocyte culture. Lab Chip 13, 3569-3577 (2013).
37. Wang, C. et al. User-interactive electronic skin for instantaneous pressure visualization. Nature Mater. 12, 899-904 (2013).
38. Huang, Y., Duan, X. & Lieber, C. M. Nanowires for integrated multicolor nanophotonics. Small 1, 142-147 (2005).
39. Takei, K. et al. Nanowire active-matrix circuitry for low-voltage macroscale artificial skin. Nature Mater. 9, 821-826 (2010).