Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation

Science

Volumn 352, Issue 6293, 2016, Pages 1576-1580

  Dutta, Aditya ^a   Le Magnen, Clémentine ^a   Mitrofanova, Antonina ^a,b   Ouyang, Xuesong ^a,c   Califano, Andrea ^a   Abate Shen, Cory ^a  

^a Department of Medicine   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c Crown Bioscience Inc   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE G9A; HOMEODOMAIN PROTEIN; PROTEIN; TRANSCRIPTION FACTOR NKX3.1; UNCLASSIFIED DRUG; UTY PROTEIN; EHMT2 PROTEIN, HUMAN; HISTOCOMPATIBILITY ANTIGEN; HISTONE LYSINE METHYLTRANSFERASE; NKX3-1 PROTEIN, HUMAN; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR; UTY PROTEIN, HUMAN;

CANCER; CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; GENE; HOMEOSTASIS; REGULATORY FRAMEWORK; RODENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY GRAFT; LOSS OF FUNCTION MUTATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE; PROSTATE CANCER; PROSTATE EPITHELIUM CELL; UPREGULATION; ANIMAL; CELL LINE; EPITHELIUM CELL; GENE SILENCING; LENTIVIRINAE; RAT;

ANIMALS; CELL LINE; EPITHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; GENE REGULATORY NETWORKS; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; HOMEODOMAIN PROTEINS; HUMANS; LENTIVIRUS; MALE; MICE; NUCLEAR PROTEINS; PROSTATE; RATS; TRANSCRIPTION FACTORS;

EID: 84976271607     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad9512     Document Type: Article

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