Association between fetal growth, cerebral blood flow and neurodevelopmental outcome in univentricular fetuses

Ultrasound in Obstetrics and Gynecology

Volumn 47, Issue 4, 2016, Pages 460-465

  Hahn, E ^a   Szwast, A ^b   Cnota, J ^a   Levine, J C ^c   Fifer, C G ^d   Jaeggi, E ^e   Andrews, H ^f   Williams, I A ^g  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

^f Columbia University ^*  (United States)

^g NewYork Presbyterian Hospital   (United States)

Author keywords

cerebral blood flow; fetuses; growth; neurodevelopment; single ventricle

Indexed keywords

ABNORMALITIES; BRAIN CIRCULATION; FEMALE; FETUS; FETUS DEVELOPMENT; FETUS ECHOGRAPHY; GESTATIONAL AGE; HEART VENTRICLE; HUMAN; MALE; MIDDLE CEREBRAL ARTERY; NEURODEVELOPMENTAL DISORDERS; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; PROCEDURES; PULSATILE FLOW; RETROSPECTIVE STUDY;

CEREBROVASCULAR CIRCULATION; FEMALE; FETAL DEVELOPMENT; FETUS; GESTATIONAL AGE; HEART VENTRICLES; HUMANS; MALE; MIDDLE CEREBRAL ARTERY; NEURODEVELOPMENTAL DISORDERS; PREGNANCY; PULSATILE FLOW; RETROSPECTIVE STUDIES; ULTRASONOGRAPHY, PRENATAL;

EID: 84975749467     PISSN: 09607692     EISSN: 14690705     Source Type: Journal    
DOI: 10.1002/uog.14881     Document Type: Article

References (19)

1. Goldberg CS, Schwartz EM, Brunberg JA, Mosca RS, Bove EL, Schork MA, Stetz SP, Cheatham JP, Kulik TJ,. Neurodevelopmental outcome of patients after the fontan operation: A comparison between children with hypoplastic left heart syndrome and other functional single ventricle lesions. J Pediatr 2000; 137: 646-652.
2. Tabbutt S, Nord AS, Jarvik GP, Bernbaum J, Wernovsky G, Gerdes M, Zackai E, Clancy RR, Nicolson SC, Spray TL, Gaynor JW,. Neurodevelopmental outcomes after staged palliation for hypoplastic left heart syndrome. Pediatrics 2008; 121: 476-483.
3. Limperopoulos C, Majnemer A, Shevell MI, Rosenblatt B, Rohlicek C, Tchervenkov C,. Neurodevelopmental status of newborns and infants with congenital heart defects before and after open heart surgery. J Pediatr 2000; 137: 638-645.
4. Limperopoulos C, Majnemer A, Shevell MI, Rosenblatt B, Rohlicek C, Tchervenkov C,. Neurologic status of newborns with congenital heart defects before open heart surgery. Pediatrics 1999; 103: 402-408.
5. Cnota JF, Hangge PT, Wang Y, Woo JG, Hinton AC, Divanovic AA, Michelfelder EC, Hinton RB,. Somatic growth trajectory in the fetus with hypoplastic left heart syndrome. Pediatr Res 2013; 74: 284-289.
6. Gaynor JW, Wernovsky G, Jarvik GP, Bernbaum J, Gerdes M, Zackai E, Nord AS, Clancy RR, Nicolson SC, Spray TL,. Patient characteristics are important determinants of neurodevelopmental outcome at one year of age after neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg 2007; 133: 1344-1353, 1353.e1-3.
7. Dubiel M, Gunnarsson GO, Gudmundsson S,. Blood redistribution in the fetal brain during chronic hypoxia. Ultrasound Obstet Gynecol 2002; 20: 117-121.
8. Peeters LL, Sheldon RE, Jones MD, Jr, Makowski EL, Meschia G,. Blood flow to fetal organs as a function of arterial oxygen content. Am J Obstet Gynecol 1979; 135: 637-646.
9. Williams IA, Fifer C, Jaeggi E, Levine JC, Michelfelder EC, Szwast AL,. The association of fetal cerebrovascular resistance with early neurodevelopment in single ventricle congenital heart disease. Am Heart J 2013; 165: 544-550.e1.
10. Bahado-Singh RO, Kovanci E, Jeffres A, Oz U, Deren O, Copel J, Mari G,. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 1999; 180: 750-756.
11. Ohye RG, Sleeper LA, Mahony L, Newburger JW, Pearson GD, Lu M, Goldberg CS, Tabbutt S, Formmelt PC, Ghanayem NS, Laussen PC, Rhodes JF, Lewis AB, Mital S, Ravishankar C, Williams IA, Dunbar-Masterson C, Atz AM, Colan S, Minich LL, Pizarro C, Kanter KR, Jaggers J, Jacobs JP, Krawczeski CD, Pike N, McCrindle BW, Virzi L, Gaynor JW,; Pediatric Heart Network Investigators. Comparison of shunt types in the Norwood procedure for single-ventricle lesions. New Engl J Med 2010; 362: 1980-1992.
12. Hsu DT, Zak V, Mahony L, Sleeper LA, Atz AM, Levine JC, Barker PC, Ravishankar C, McCrindle BW, Williams RV, Altmann K, Ghanayem NS, Margossian R, Chung WK, Border WL, Pearson GD, Stylianou MP, Mital S,; Pediatric Heart Network Investigators. Enalapril in infants with single ventricle: results of a multicenter randomized trial. Circulation 2010; 122: 333-340.
13. nd edn. The Psychological Corporation: San Antonio, TX, 1993.
14. Hadlock FP, Deter RL, Harrist RB, Park SK,. Estimating fetal age: computer-assisted analysis of multiple fetal growth parameters. Radiology 1984; 152: 497-501.
15. Arduini D, Rizzo G,. Normal values of Pulsatility Index from fetal vessels: a cross-sectional study on 1556 healthy fetuses. J Perinat Med 1990; 18: 165-172.
16. Kaltman JR, Di H, Tian Z, Rychik J,. Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus. Ultrasound Obstet Gynecol 2005; 25: 32-36.
17. van Batenburg-Eddes T, de Groot L, Steegers EA, Hofman A, Jaddoe VW, Verhulst FC, Tiemeier H,. Fetal programming of infant neuromotor development: the generation R study. Pediatr Res 2010; 67: 132-137.
18. Georgieff MK,. Nutrition and the developing brain: nutrient priorities and measurement. Am J Clin Nutr 2007; 85: 614S-620S.
19. Limperopoulos C, Tworetzky W, McElhinney DB, Newburger JW, Brown DW, Robertson RL, Jr, Guizard N, McGrath E, Geva J, Annese D, Dunbar-Masterson C, Trainor B, Laussen PC, duPlessis AJ,. Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy. Circulation 2010; 121: 26-33.