The Pseudomonas aeruginosa efflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 25, 2016, Pages E3538-E3547

  Sakhtah, Hassan ^a   Koyama, Leslie ^a,d   Zhang, Yihan ^b   Morales, Diana K ^a,c,e   Fields, Blanche L ^a   Price Whelan, Alexa ^a   Hogan, Deborah A ^c   Shepard, Kenneth ^b   Dietrich, Lars E P ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b Geisel School of Medicine at Dartmouth ^*  (United States)

^c DARTMOUTH MEDICAL SCHOOL   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Antibiotic; Biofilm; MexGHI OpmD; Phenazine; RND efflux

Indexed keywords

CARBOXYLIC ACID; MEMBRANE PROTEIN; METHYL GROUP; MEX PROTEIN; PHENAZINE DERIVATIVE; PYOCYANINE; UNCLASSIFIED DRUG; 5-METHYLPHENAZINE-1-CARBOXYLIC ACID; BACTERIAL PROTEIN; CARRIER PROTEIN;

ARTICLE; BIOFILM; BIOSYNTHESIS; COLONY FORMATION; CONTROLLED STUDY; ELECTROCHEMICAL DETECTION; ELECTRON TRANSPORT; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MORPHOGENESIS; NONHUMAN; OPERON; OUTER MEMBRANE; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY;

BACTERIAL PROTEINS; BIOFILMS; CARRIER PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; PHENAZINES; PSEUDOMONAS AERUGINOSA;

EID: 84975740665     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1600424113     Document Type: Article

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