Elevated Neurosteroids in the Lateral Thalamus Relieve Neuropathic Pain in Rats with Spared Nerve Injury

Neuroscience Bulletin

Volumn 32, Issue 4, 2016, Pages 311-322

  Zhang, Meng ^a   Liu, Jia ^a   Zhou, Meng Meng ^a   Wu, Honghai ^b   Hou, Yanning ^b   Li, Yun Feng ^c   Yin, Yuxin ^a   Zheng, Lemin ^d   Liu, Feng Yu ^a   Yi, Ming ^a   Wan, You ^a,e  

^a PEKING UNIVERSITY   (China)

^b BETHUNE INTERNATIONAL PEACE HOSPITAL   (China)

^c BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^d Peking University   (China)

^e PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

GABAA receptors; Neurosteroids; Spared nerve injury; Thalamus; Translocator protein

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; DEOXYCORTICOSTERONE; EMAPUNIL; METHYLTESTOSTERONE; PREGNENOLONE; PROGESTERONE; TETRAHYDRODEOXYCORTICOSTERONE; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ACTIN BINDING PROTEIN; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AIF1 PROTEIN, RAT; ANTINEOPLASTIC AGENT; BICUCULLINE; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; ENOLASE; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOQUINOLINE DERIVATIVE; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; N-BENZYL-N-ETHYL-2-(7,8-DIHYDRO-7-METHYL-8-OXO-2-PHENYL-9H-PURIN-9-YL)ACETAMIDE; PURINE DERIVATIVE; TSPO PROTEIN, RAT;

ADULT; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CHINA; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOFLUORESCENCE; IN VIVO STUDY; MALE; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PHARMACOLOGY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SPARED NERVE INJURY; STEROIDOGENESIS; TANDEM MASS SPECTROMETRY; THALAMUS LATERAL NUCLEUS; THALAMUS RETICULAR NUCLEUS; TOXICOLOGY; UPREGULATION; ANIMAL; DISEASE MODEL; DRUG EFFECTS; HYPERALGESIA; METABOLISM; MOUSE; PAIN MEASUREMENT; SCIATICA; SPRAGUE DAWLEY RAT; THALAMUS;

ANIMALS; ANTINEOPLASTIC AGENTS; BICUCULLINE; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; DISEASE MODELS, ANIMAL; GABA ANTAGONISTS; GLIAL FIBRILLARY ACIDIC PROTEIN; HYPERALGESIA; ISOQUINOLINES; MICE; MICROFILAMENT PROTEINS; NEUROTRANSMITTER AGENTS; PAIN MEASUREMENT; PHOSPHOPYRUVATE HYDRATASE; PURINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SCIATICA; THALAMUS; UP-REGULATION;

EID: 84975324446     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-016-0044-7     Document Type: Article

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