Experience-dependent accumulation of N6-methyladenosine in the prefrontal cortex is associated with memory processes in mice

Journal of Neuroscience

Volumn 36, Issue 25, 2016, Pages 6771-6777

  Widagdo, Jocelyn ^a   Zhao, Qiong Yi ^a   Kempen, Marie Jeanne ^a   Tan, Men Chee ^a   Ratnu, Vikram S ^a   Wei, Wei ^a   Leighton, Laura ^a   Spadaro, Paola A ^a   Edson, Janette ^a   Anggono, Victor ^a   Bredy, Timothy W ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Epigenetics; Memory; MRNA stability; RNA methylation; Synaptic plasticity; Transcription

Indexed keywords

6 N METHYLADENOSINE; EARLY GROWTH RESPONSE FACTOR 1; LENTIVIRUS VECTOR; MESSENGER RNA; NICOTINAMIDE METHYLTRANSFERASE; SHORT HAIRPIN RNA; TRANSCRIPTOME; ADENOSINE; ALPHA KETOGLUTARATE DEPENDENT DIOXYGENASE FTO; FTO PROTEIN, MOUSE; N(6)-METHYLADENOSINE; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; DNA BINDING MOTIF; ELEVATED PLUS MAZE TEST; EPIGENETICS; FEAR; GENE EXPRESSION REGULATION; GENE SILENCING; IMMUNOPRECIPITATION; MALE; MEDIAL PREFRONTAL CORTEX; MEMORY; MOUSE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NONHUMAN; OPEN FIELD BEHAVIOR; PLASMID; PRIORITY JOURNAL; QUALITY CONTROL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA METHYLATION; RNA STABILITY; SEQUENCE ALIGNMENT; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ASSOCIATION; C57BL MOUSE; CELL CULTURE; CONDITIONED REFLEX; CYTOLOGY; EXPLORATORY BEHAVIOR; GENE EXPRESSION PROFILING; GENETICS; MAMMALIAN EMBRYO; MAZE TEST; METABOLISM; NERVE CELL; PHYSIOLOGY; PREFRONTAL CORTEX; PROTEIN DEGRADATION; TRANSGENIC MOUSE;

ADENOSINE; ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO; ANIMALS; CELLS, CULTURED; CONDITIONING, CLASSICAL; CUES; EMBRYO, MAMMALIAN; EXPLORATORY BEHAVIOR; FEAR; GENE EXPRESSION PROFILING; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURONS; PREFRONTAL CORTEX; PROTEOLYSIS; RNA, SMALL INTERFERING;

EID: 84975321429     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4053-15.2016     Document Type: Article

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