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Volumn 22, Issue 6, 2016, Pages 450-457

Reduction of fasting blood glucose and hemoglobin A1C using oral aloe vera: A meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

ALOE VERA EXTRACT; FRUCTOSAMINE; GLUCOSE; HEMOGLOBIN A1C; INSULIN; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; PLANT EXTRACT;

EID: 84975317598     PISSN: 10755535     EISSN: 15577708     Source Type: Journal    
DOI: 10.1089/acm.2015.0122     Document Type: Article
Times cited : (14)

References (47)
  • 1
    • 84883323469 scopus 로고    scopus 로고
    • World Diabetes Foundation. Online document at Accessed August 19 2014
    • World Diabetes Foundation. Annual Review 2013. Online document at: http://worldiabetesfoundation.org/stories/annual-review-2013. Accessed August 19, 2014.
    • (2013) Annual Review
  • 2
    • 84964992629 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention Online document at Accessed August 18. 2014
    • Centers for Disease Control and Prevention. National Diabetes Statistics Report, 2014. Online document at: http://www.cdc.gov//diabetes/pubs/statsreport14/nationaldiabetes-report-web.pdf. Accessed August 18, 2014.
    • (2014) National Diabetes Statistics Report
  • 3
    • 41949103818 scopus 로고    scopus 로고
    • An overview of Indian novel traditional medicinal plants with antidiabetic potentials
    • Gupta R, Bajpai KG, John S, Saxena AM. An overview of Indian novel traditional medicinal plants with antidiabetic potentials. Afr J Trod Comp Alt Med 2008; 5: 1-17.
    • (2008) Afr J Trod Comp Alt Med , vol.5 , pp. 1-17
    • Gupta, R.1    Bajpai, K.G.2    John, S.3    Saxena, A.M.4
  • 4
    • 73749086904 scopus 로고    scopus 로고
    • Mortality attributable to diabetes: Estimates for the year 2010
    • Roglic G, Unwin N. Mortality attributable to diabetes: estimates for the year 2010. Diabetes ResClin Pract 2010; 87: 1-19.
    • (2010) Diabetes ResClin Pract , vol.87 , pp. 1-19
    • Roglic, G.1    Unwin, N.2
  • 5
    • 84975856269 scopus 로고    scopus 로고
    • Economic costs of diabetics in the US in 2012
    • Diabetes Association A
    • American Diabetes Association. Economic costs of diabetics in the US in 2012. Diabetes Care 2013; 36: 1033-1046.
    • (2013) Diabetes Care , vol.36 , pp. 1033-1046
  • 6
    • 84968822322 scopus 로고    scopus 로고
    • International Diabetes Federation Online document at Accessed August 19
    • International Diabetes Federation. IDF Diabetes Atlas, sixth edition. Online document at: http://idf.org/diabetesatlas/economic-impacts-diabetes. Accessed August 19, 2014.
    • (2014) IDF Diabetes Atlas, Sixth Edition
  • 7
    • 79952196958 scopus 로고    scopus 로고
    • Oral aloe vera for treatment of diabetes mellitus and dyslipidemia
    • 1804 1806 1808
    • Ngo MQ, Nguyen NN, Shah SA. Oral aloe vera for treatment of diabetes mellitus and dyslipidemia. Am J Health Syst Pharm 2010; 67: 1804, 1806, 1808.
    • (2010) Am J Health Syst Pharm , vol.67
    • Ngo, M.Q.1    Nguyen, N.N.2    Shah, S.A.3
  • 8
    • 84874545351 scopus 로고    scopus 로고
    • Nutritional supplements and their effect on glucose control
    • Lee T, Dugoua JJ. Nutritional supplements and their effect on glucose control. Adv Exp Med Biol 2012; 771: 381-395.
    • (2012) Adv Exp Med Biol , vol.771 , pp. 381-395
    • Lee, T.1    Dugoua, J.J.2
  • 10
    • 84975265584 scopus 로고    scopus 로고
    • The International Aloe Science Council Online document at Accessed January 26
    • The International Aloe Science Council. IASC aloe vera FAQ, version 1.0. Online document at: http://www.iasc.org/faq.html. Accessed January 26, 2015.
    • (2015) IASC Aloe Vera FAQ, Version 1.0
  • 12
    • 0032854467 scopus 로고    scopus 로고
    • Aloe vera: A systematic review of its clinical effectiveness
    • Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999; 49: 823-828.
    • (1999) Br J Gen Pract , vol.49 , pp. 823-828
    • Vogler, B.K.1    Ernst, E.2
  • 13
    • 58149171455 scopus 로고    scopus 로고
    • An evidence-based systematic review of aloe vera by the Natural Standard Research Collaboration
    • Ulbricht C, Armstrong J, Basch E, et al. An evidence-based systematic review of aloe vera by the Natural Standard Research Collaboration. JHerb Pharmacother 2007; 7: 279-323.
    • (2007) JHerb Pharmacother , vol.7 , pp. 279-323
    • Ulbricht, C.1    Armstrong, J.2    Basch, E.3
  • 15
    • 0042668497 scopus 로고    scopus 로고
    • Systematic review of herbs and dietary supplements for glycemic control in diabetes
    • Yeh GY, Eisenburg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003; 26: 1277-1294.
    • (2003) Diabetes Care , vol.26 , pp. 1277-1294
    • Yeh, G.Y.1    Eisenburg, D.M.2    Kaptchuk, T.J.3    Phillips, R.S.4
  • 16
    • 84891275275 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effect of Aloe vera L in non-insulin dependent diabetics
    • Choudhary M, Kochar A, Sangha J. Hypoglycemic and hypolipidemic effect of Aloe vera L. in non-insulin dependent diabetics. J Food Sci Tecnol 2014; 51: 90-96.
    • (2014) J Food Sci Tecnol , vol.51 , pp. 90-96
    • Choudhary, M.1    Kochar, A.2    Sangha, J.3
  • 17
    • 72549098607 scopus 로고    scopus 로고
    • Possible hypoglycemic effect of Aloe vera L high molecular weight fractions on type 2 diabetic patients
    • Yagi A, Hegazy S, Kabbash A, Wahab EA. Possible hypoglycemic effect of Aloe vera L. high molecular weight fractions on type 2 diabetic patients. Saudi Pharm J. 2009; 17: -209-215.
    • (2009) Saudi Pharm J. , vol.17 , pp. 209-215
    • Yagi, A.1    Hegazy, S.2    Kabbash, A.3    Wahab, E.A.4
  • 19
    • 0001760557 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera L juice II Clinical trial in diabetes mellitus patients in combination with glibenclamide
    • Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine 1996; 3: -245-248.
    • (1996) Phytomedicine , vol.3 , pp. 245-248
    • Bunyapraphatsara, N.1    Yongchaiyudha, S.2    Rungpitarangsi, V.3    Chokechaijaroenporn, O.4
  • 21
    • 84858151895 scopus 로고    scopus 로고
    • Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: A randomized double-blind placebo-controlled clinical trial
    • Huseini HF, Kianbakht S, Hajiaghaee R, Dabaghian FH. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012; 78: 311-316.
    • (2012) Planta Med , vol.78 , pp. 311-316
    • Huseini, H.F.1    Kianbakht, S.2    Hajiaghaee, R.3    Dabaghian, F.H.4
  • 22
    • 84881367993 scopus 로고    scopus 로고
    • Metabolic effects of aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: Randomized controlled trial
    • Choi HC, Kim SJ, Son KY, Oh BJ, Cho BL. Metabolic effects of aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: randomized controlled trial. Nutrition 2013; 29: 1110-1114.
    • (2013) Nutrition , vol.29 , pp. 1110-1114
    • Choi, H.C.1    Kim, S.J.2    Son, K.Y.3    Oh, B.J.4    Cho, B.L.5
  • 23
    • 0022469014 scopus 로고
    • The antidiabetic activity of aloes: Preliminary clinical and experimental observations
    • Ghannam N, Kingston M, Al-Meshaal IA, et al. The antidiabetic activity of aloes: preliminary clinical and experimental observations. Horm Res 1986; 24: 288-294.
    • (1986) Horm Res , vol.24 , pp. 288-294
    • Ghannam, N.1    Kingston, M.2    Al-Meshaal, I.A.3
  • 24
    • 62249115015 scopus 로고    scopus 로고
    • Efficacy of Aloe vera juice consumption on glycemic response in Type-2 diabetic patients
    • Arora D, Goyal M, Agarwal RP. Efficacy of Aloe vera juice consumption on glycemic response in Type-2 diabetic patients. Int J Food Sci Tech. 2009; 46: 160-162.
    • (2009) Int J Food Sci Tech , vol.46 , pp. 160-162
    • Arora, D.1    Goyal, M.2    Agarwal, R.P.3
  • 25
    • 0023216603 scopus 로고
    • Studies on the activity of individual plants of an antidiabetic mixture
    • Al-Awadi FM, Gumaa KA. Studies on the activity of individual plants of an antidiabetic mixture. Acta Diabetol Lat 1987; 24: 37-41.
    • (1987) Acta Diabetol Lat , vol.24 , pp. 37-41
    • Al-Awadi, F.M.1    Gumaa, K.A.2
  • 26
    • 33745714081 scopus 로고    scopus 로고
    • Identification of five phytosterols from Aloe vera gel as anti-diabetic compounds
    • Tanaka M, Misawa E, Ito Y, et al. Identification of five phytosterols from Aloe vera gel as anti-diabetic compounds. Biol Pharm Bull 2006; 29: 1418-1422.
    • (2006) Biol Pharm Bull , vol.29 , pp. 1418-1422
    • Tanaka, M.1    Misawa, E.2    Ito, Y.3
  • 27
    • 33645054804 scopus 로고    scopus 로고
    • Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes
    • Rajasekaran S, Ravi K, Sivagnanam K et al. Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes. Clin Exp Pharmacol Physiol 2006; 33: 232-237.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 232-237
    • Rajasekaran, S.1    Ravi, K.2    Et, Al.S.K.3
  • 28
    • 67650568107 scopus 로고    scopus 로고
    • Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus
    • Kim K, Kim H, Kwon J, et al. Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. Phytomedicine 2009; 16: 856-863.
    • (2009) Phytomedicine , vol.16 , pp. 856-863
    • Kim, K.1    Kim, H.2    Kwon, J.3
  • 29
    • 37849051676 scopus 로고    scopus 로고
    • Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice
    • Perez YY, Jimenes-Ferrer E, Zamilpa A, et al. Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice. Am J Chin Med 2007; 35: 1037-1046.
    • (2007) Am J Chin Med , vol.35 , pp. 1037-1046
    • Perez, Y.Y.1    Jimenes-Ferrer, E.2    Zamilpa, A.3
  • 30
    • 0025234740 scopus 로고
    • Effect of aloes on blood glucose levels in normal and alloxan diabetic mice
    • Ajabnoor M.A. Effect of aloes on blood glucose levels in normal and alloxan diabetic mice. J Ethnopharmacol 1990; 28: 215-220.
    • (1990) J Ethnopharmacol , vol.28 , pp. 215-220
    • Ajabnoor, M.A.1
  • 31
    • 0026269341 scopus 로고
    • The effect of a plants mixture extract on liver gluconeogenesis in streptozotocin induced diabetic rats
    • Al-Awadi F, Fatania H, Shamte U. The effect of a plants mixture extract on liver gluconeogenesis in streptozotocin induced diabetic rats. Diabetes Res 1991; 18: 163-168.
    • (1991) Diabetes Res , vol.18 , pp. 163-168
    • Al-Awadi, F.1    Fatania, H.2    Shamte, U.3
  • 32
    • 84863346623 scopus 로고    scopus 로고
    • Oral ingestion of aloe vera phytosterols alters hepatic gene expression profiles and ameliorates obesity-Associated metabolic disorders in Zucker diabetic fatty rats
    • Misawa E, Tanaka M, Nomaguchi K, et al. Oral ingestion of aloe vera phytosterols alters hepatic gene expression profiles and ameliorates obesity-Associated metabolic disorders in Zucker diabetic fatty rats. J Agric Food Chem 2012; 60: 2799-2806.
    • (2012) J Agric Food Chem , vol.60 , pp. 2799-2806
    • Misawa, E.1    Tanaka, M.2    Nomaguchi, K.3
  • 33
    • 84870720646 scopus 로고    scopus 로고
    • Dietary aloe reduces adipogenesis via the activation of AMPK and suppresses obesity-related inflammation in obese mice
    • Shin E, Shin S, Kong H, et al. Dietary aloe reduces adipogenesis via the activation of AMPK and suppresses obesity-related inflammation in obese mice. Immune Netw 2011; 11: 107-113.
    • (2011) Immune Netw , vol.11 , pp. 107-113
    • Shin, E.1    Shin, S.2    Kong, H.3
  • 34
    • 0344131271 scopus 로고    scopus 로고
    • Aloe vera revisited
    • Atherton P. Aloe vera revisited. Br J Phytother 1998; 4: 176-183.
    • (1998) Br J Phytother , vol.4 , pp. 176-183
    • Atherton, P.1
  • 35
    • 0026330047 scopus 로고
    • Aloe vera: Its chemical and therapeutic properties
    • Shelton RM. Aloe vera: its chemical and therapeutic properties. Int J Dermatol 1991; 30: 679-683.
    • (1991) Int J Dermatol , vol.30 , pp. 679-683
    • Shelton, R.M.1
  • 36
    • 77952853260 scopus 로고    scopus 로고
    • Study on the analysis of trace elements in Aloe vera and its biological importance
    • Rajendran A, Narayanan V, Gnanavel I. Study on the analysis of trace elements in Aloe vera and its biological importance. J Appl Sci Res 2007; 3: 1476-1478.
    • (2007) J Appl Sci Res , vol.3 , pp. 1476-1478
    • Rajendran, A.1    Narayanan, V.2    Gnanavel, I.3
  • 37
    • 0024506449 scopus 로고
    • Toxicity studies on six plants used in the traditional Arab system of medicine
    • Shah AH, Qureshi S, Tariq M, Ageel AM. Toxicity studies on six plants used in the traditional Arab system of medicine. Phytother Res 1989; 3: 25-29.
    • (1989) Phytother Res , vol.3 , pp. 25-29
    • Shah, A.H.1    Qureshi, S.2    Tariq, M.3    Ageel, A.M.4
  • 39
    • 12344287967 scopus 로고    scopus 로고
    • Acute hepatitis induced by an aloe vera preparation: A case report
    • Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an aloe vera preparation: a case report. World J Gastroenterol 2005; 11: 303-304.
    • (2005) World J Gastroenterol , vol.11 , pp. 303-304
    • Rabe, C.1    Musch, A.2    Schirmacher, P.3
  • 40
    • 23744493940 scopus 로고    scopus 로고
    • Aloe linked to thyroid dysfunction
    • Pigatto PD, Guzzi G. Aloe linked to thyroid dysfunction. Arch Med Res 2005; 36: 608.
    • (2005) Arch Med Res , vol.36 , pp. 608
    • Pigatto, P.D.1    Guzzi, G.2
  • 41
    • 84975226800 scopus 로고    scopus 로고
    • Natural Medicines Comprehensive Database Online document at Accessed February 1
    • Natural Medicines Comprehensive Database. Aloe monograph. Online document at: http://www.naturaldatabase .therapeuticresearch.com. Accessed February 1, 2015.
    • (2015) Aloe Monograph
  • 42
    • 84975271397 scopus 로고    scopus 로고
    • Aloecorp Online documen at Accessed February 1
    • Aloecorp. GRAS status given to Qmatrix. Online documen at: http://www.aloecorp.com/news-release/gras-status-givenqmatrix. Accessed February 1, 2015.
    • (2015) GRAS Status Given to Qmatrix
  • 43
    • 84975271392 scopus 로고    scopus 로고
    • Online document at Accessed February 1, 2015
    • Terry Laboratories. Terry laboratories receives GRAS status. Online document at: http://blog.terrylabs.com/2012/04/18/terry-laboratories-receives-gras-status/. Accessed February 1, 2015.
    • Terry Laboratories Terry Laboratories Receives GRAS Status
  • 44
    • 84975293905 scopus 로고    scopus 로고
    • Natural Products Insider Online documen at Accessed February 1
    • Natural Products Insider. Pharmachem Laboratories Inc. obtains GRAS status. Online documen at: http://www .naturalproductsinsider.com/News/2013/11/Pharmachem-Laboratories-Inc-Obtains-GRAS-Status.aspx?topic=aloe-vera. Accessed February 1, 2015.
    • (2015) Pharmachem Laboratories Inc. Obtains GRAS Status
  • 45
    • 84975293919 scopus 로고    scopus 로고
    • The International Aloe Science Council Accessed February 1
    • The International Aloe Science Council. Certification Program. Online document at: http://www.iasc.org/certify .html. Accessed February 1, 2015.
    • (2015) Certification Program. Online Document at
  • 46
    • 77951970320 scopus 로고    scopus 로고
    • Liraglutide: A human GLP-1 analogue for the treatment of type 2 diabetes
    • Sakauye SD, Shah SA. Liraglutide: a human GLP-1 analogue for the treatment of type 2 diabetes. Formulary 2009; 44: 136-142.
    • (2009) Formulary , vol.44 , pp. 136-142
    • Sakauye, S.D.1    Shah, S.A.2
  • 47
    • 84929264242 scopus 로고    scopus 로고
    • Final report of the cosmetic ingredient review
    • Bergfield WF. Final report of the cosmetic ingredient review. Int J Toxicol 2007; 26: 1-50.
    • (2007) Int J Toxicol , vol.26 , pp. 1-50
    • Bergfield, W.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.