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Volumn 78, Issue 4, 2012, Pages 311-316

Anti-hyperglycemic and anti-hypercholesterolemic effects of aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: A randomized double-blind placebo-controlled clinical trial

Author keywords

Aloe vera; diabetes; hyperlipidemia; Liliaceae; patient

Indexed keywords

ALOE VERA LEAF GEL; ANTILIPEMIC AGENT; CHOLESTEROL; GLIBENCLAMIDE; GLUCOSE; HEMOGLOBIN A1C; HERBACEOUS AGENT; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; METFORMIN; ORAL ANTIDIABETIC AGENT; PLACEBO; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84858151895     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1280474     Document Type: Article
Times cited : (123)

References (28)
  • 1
    • 70350517412 scopus 로고    scopus 로고
    • Type 2 diabetes: Where we are today: An overview of disease burden, current treatments, and treatment strategies
    • Campbell RK. Type 2 diabetes: where we are today: an overview of disease burden, current treatments, and treatment strategies. J AmPharm Assoc 2009; 49: S3-S9
    • (2009) J AmPharm Assoc , vol.49
    • Campbell, R.K.1
  • 2
    • 34249288293 scopus 로고    scopus 로고
    • New frontiers in the management of type 2 diabetes
    • Mudaliar S. New frontiers in the management of type 2 diabetes. Indian J Med Res 2007; 125: 275-296 (Pubitemid 46805448)
    • (2007) Indian Journal of Medical Research , vol.125 , Issue.3 , pp. 275-296
    • Mudaliar, S.1
  • 3
    • 41149126432 scopus 로고    scopus 로고
    • Targets for intervention in dyslipidemia in diabetes
    • Tomkin GH. Targets for intervention in dyslipidemia in diabetes. Diabetes Care 2008; 31: S241-S248
    • (2008) Diabetes Care , vol.31
    • Tomkin, G.H.1
  • 4
    • 36148989501 scopus 로고    scopus 로고
    • Optimizing combination treatment in the management of type 2 diabetes
    • Derosa G, Sibilla S. Optimizing combination treatment in the management of type 2 diabetes. Vasc Health Risk Manag 2007; 3: 665-671 (Pubitemid 350104122)
    • (2007) Vascular Health and Risk Management , vol.3 , Issue.5 , pp. 665-671
    • Derosa, G.1    Sibilla, S.2
  • 5
    • 66749130805 scopus 로고    scopus 로고
    • Managing diabetic dyslipidemia: Aggressive approach
    • Spratt KA. Managing diabetic dyslipidemia: aggressive approach. J Am Osteopath Assoc 2009; 109: S2-S7
    • (2009) J Am Osteopath Assoc , vol.109
    • Spratt, K.A.1
  • 6
    • 10044240704 scopus 로고    scopus 로고
    • Comparative effects of lipid-lowering therapies
    • DOI 10.1016/j.pcad.2004.04.007, PII S0033062004000167
    • Davidson MH, Toth PP. Comparative effects of lipid-lowering therapies. Prog Cardiovasc Dis 2004; 47: 73-104 (Pubitemid 39600944)
    • (2004) Progress in Cardiovascular Diseases , vol.47 , Issue.2 , pp. 73-104
    • Davidson, M.H.1    Toth, P.P.2
  • 7
    • 13644263258 scopus 로고    scopus 로고
    • Oral antidiabetic agents: Current role in type 2 diabetes mellitus
    • DOI 10.2165/00003495-200565030-00005
    • Krentz AJ, Bailey CJ. Oral antidiabetic agents: current role in type 2 diabetes mellitus. Drugs 2005; 65: 385-411 (Pubitemid 40227460)
    • (2005) Drugs , vol.65 , Issue.3 , pp. 385-411
    • Krentz, A.J.1    Bailey, C.J.2
  • 8
    • 13844314826 scopus 로고    scopus 로고
    • Herbal or natural medicines as modulators of peroxisome proliferator-activated receptors and related nuclear receptors for therapy of metabolic syndrome
    • DOI 10.1111/j.1742-7843.2005.pto960102.x
    • Huang THW, Kota BP, Razmovski V, Roufogalis BD. Herbal or natural medicines as modulators of peroxisome proliferator-activated receptors and related nuclear receptors for therapy of metabolic syndrome. Basic Clin Pharmacol Toxicol 2005; 96: 3-14 (Pubitemid 40260842)
    • (2005) Basic and Clinical Pharmacology and Toxicology , vol.96 , Issue.1 , pp. 3-14
    • Huang, T.H.-W.1    Kota, B.P.2    Razmovski, V.3    Roufogalis, B.D.4
  • 9
    • 0034090223 scopus 로고    scopus 로고
    • Herbs and dietary supplements in the prevention and treatment of cardiovascular disease
    • Fugh-Berman A. Herbs and dietary supplements in the prevention and treatment of cardiovascular disease. Prev Cardiol 2000; 3: 24-32 (Pubitemid 30217399)
    • (2000) Preventive Cardiology , vol.3 , Issue.1 , pp. 24-32
    • Fugh-Berman, A.1
  • 11
    • 33748428494 scopus 로고    scopus 로고
    • A reason to season: The therapeutic benefits of spices and culinary herbs
    • Low Dog T. A reason to season: the therapeutic benefits of spices and culinary herbs. Explore 2006; 2: 446-449
    • (2006) Explore , vol.2 , pp. 446-449
    • Low Dog, T.1
  • 12
    • 77956629122 scopus 로고    scopus 로고
    • Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycemic potential in the treatment of diabetes: An update
    • Tundis R, Loizzo MR, Menichini F. Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycemic potential in the treatment of diabetes: an update. Mini Rev Med Chem 2010; 10: 315-331
    • (2010) Mini Rev Med Chem , vol.10 , pp. 315-331
    • Tundis, R.1    Loizzo, M.R.2    Menichini, F.3
  • 13
    • 0032854467 scopus 로고    scopus 로고
    • Aloe vera: A systematic review of its clinical effectiveness
    • Vogler BK. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999; 49: 823-828 (Pubitemid 29465424)
    • (1999) British Journal of General Practice , vol.49 , Issue.447 , pp. 823-828
    • Vogler, B.K.1    Ernst, E.2
  • 14
    • 0042668497 scopus 로고    scopus 로고
    • Systematic review of herbs and dietary supplements for glycemic control in diabetes
    • DOI 10.2337/diacare.26.4.1277
    • Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabet Care 2003; 26: 1277-1294 (Pubitemid 36929285)
    • (2003) Diabetes Care , vol.26 , Issue.4 , pp. 1277-1294
    • Yeh, G.Y.1    Eisenberg, D.M.2    Kaptchuk, T.J.3    Phillips, R.S.4
  • 16
    • 33645054804 scopus 로고    scopus 로고
    • Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozocin diabetes
    • Rajasekaran S, Ravi K, Sivagnanam K, Subramanian S. Beneficial effects of Aloe vera leaf gel extract on lipid profile status in rats with streptozocin diabetes. Clin Exp Pharmacol Physiol 2006; 33: 232-237
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 232-237
    • Rajasekaran, S.1    Ravi, K.2    Sivagnanam, K.3    Subramanian, S.4
  • 17
    • 0344131266 scopus 로고
    • Effecto del aloe sobre la hiperlipidemia en pacientes refractarios a la dieta
    • Nassiff HA, Fajardo F, Velez F. Effecto del aloe sobre la hiperlipidemia en pacientes refractarios a la dieta. Rev Cuba Med Gen Integr 1993; 9: 43-51
    • (1993) Rev Cuba Med Gen Integr , vol.9 , pp. 43-51
    • Nassiff, H.A.1    Fajardo, F.2    Velez, F.3
  • 18
    • 0022469014 scopus 로고
    • The antidiabetic activity of aloes: Preliminary clinical and experimental observations
    • Ghannam N, Kingston M, Al-Meshaal IA, Tariq M, Parman NS, Woodhouse N. The antidiabetic activity of aloes: preliminary clinical and experimental observations. Horm Res 1986; 24: 288-294 (Pubitemid 16004133)
    • (1986) Hormone Research , vol.24 , Issue.4 , pp. 288-294
    • Ghannam, N.1    Kingston, M.2    Al-Meshaal, I.A.3
  • 19
    • 0025234740 scopus 로고
    • Effect of aloes on blood glucose levels in normal and alloxan diabetic mice
    • Ajabnoor MA. Effect of aloes on blood glucose levels in normal and alloxan diabetic mice. J Ethnopharmacol 1990; 28: 215-220 (Pubitemid 20086039)
    • (1990) Journal of Ethnopharmacology , vol.28 , Issue.2 , pp. 215-220
    • Ajabnoor, M.A.1
  • 20
    • 0028310072 scopus 로고
    • Aloe vera: Antiulcer and antidiabetic effects
    • Koo ML. Aloe vera: antiulcer and antidiabetic effects. Phytother Res 1994; 8: 461-464
    • (1994) Phytother Res , vol.8 , pp. 461-464
    • Koo, M.L.1
  • 21
    • 0002249094 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus
    • Yongchaiyudha S, Rungpitarangsi V, Bunyapraphatsara N, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine 1996; 3: 241-243 (Pubitemid 126504564)
    • (1996) Phytomedicine , vol.3 , Issue.3 , pp. 241-243
    • Yongchaiyudha, S.1    Rungpitarangsi, V.2    Bunyapraphatsara, N.3    Chokechaijaroenporn, O.4
  • 22
    • 0035067049 scopus 로고    scopus 로고
    • Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models
    • Oykar A, Can A, Akev N, Baktir G, Sutlupinar N. Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models. Phytother Res 2001; 15: 157-161
    • (2001) Phytother Res , vol.15 , pp. 157-161
    • Oykar, A.1    Can, A.2    Akev, N.3    Baktir, G.4    Sutlupinar, N.5
  • 23
    • 0001760557 scopus 로고    scopus 로고
    • Antidiabetic activity of Aloe vera L. juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide
    • Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L. juice. II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine 1996; 3: 245-248 (Pubitemid 126504565)
    • (1996) Phytomedicine , vol.3 , Issue.3 , pp. 245-248
    • Bunyapraphatsara, N.1    Yongchaiyudha, S.2    Rungpitarangsi, V.3    Chokechaijaroenporn, O.4
  • 26
    • 28644434365 scopus 로고    scopus 로고
    • Mineral contents of Aloe vera leaf gel and their role on streptozotocin-induced diabetic rats
    • DOI 10.1385/BTER:108:1-3:185
    • Rajasekaran S, Sivagnanam K, Subramanian S. Mineral contents of Aloe vera leaf gel and their role on streptozocin-induced diabetic rats. Biol Trace Elem Res 2005; 108: 185-195 (Pubitemid 41752511)
    • (2005) Biological Trace Element Research , vol.108 , Issue.1-3 , pp. 185-195
    • Rajasekaran, S.1    Sivagnanam, K.2    Subramanian, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.