Privileged antigen presentation in splenic b cell follicles maximizes t cell responses in prime-boost vaccination

Journal of Immunology

Volumn 196, Issue 11, 2016, Pages 4587-4595

  Bridle, Byram W ^a   Nguyen, Andrew ^b   Salem, Omar ^b   Zhang, Liang ^b   Koshy, Sandeep ^b   Clouthier, Derek ^b   Chen, Lan ^b   Pol, Jonathan ^b   Swift, Stephanie L ^b   Bowdish, Dawn M E ^b   Lichty, Brian D ^b   Bramson, Jonathan L ^b   Wan, Yonghong ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; DOPACHROME TAUTOMERASE; RHABDOVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR; VIRUS VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; EFFECTOR CELL; IMMUNIZATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; VACCINATION; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOLOGY; FOLLICULAR DENDRITIC CELL; IMMUNOLOGY; KNOCKOUT MOUSE; SPLEEN; VESICULAR STOMATITIS INDIANA VIRUS;

ANIMALS; ANTIGEN PRESENTATION; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS, FOLLICULAR; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SPLEEN; VESICULAR STOMATITIS INDIANA VIRUS; VIRAL VACCINES;

EID: 84975144649     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600106     Document Type: Article

References (42)

1. Woodland, D. L. 2004. Jump-starting the immune system: prime-boosting comes of age. Trends Immunol. 25: 98-104.
2. Lanzavecchia, A., and F. Sallusto. 2005. Understanding the generation and function of memory T cell subsets. Curr. Opin. Immunol. 17: 326-332.
3. Wong, P., M. Lara-Tejero, A. Ploss, I. Leiner, and E. G. Pamer. 2004. Rapid development of T cell memory. J. Immunol. 172: 7239-7245.
4. + T cells can protect APC from CTL-mediated elimination. J. Immunol. 176: 7379-7384.
5. + T cells in vivo: implications for adaptive immunotherapy. Eur. J. Immunol. 31: 1772-1779.
6. Allan, R. S., J. Waithman, S. Bedoui, C. M. Jones, J. A. Villadangos, Y. Zhan, A. M. Lew, K. Shortman, W. R. Heath, and F. R. Carbone. 2006. Migratory dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. Immunity 25: 153-162.
7. Allenspach, E. J., M. P. Lemos, P. M. Porrett, L. A. Turka, and T. M. Laufer. 2008. Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells. Immunity 29: 795-806.
8. Lee, H. K., M. Zamora, M. M. Linehan, N. Iijima, D. Gonzalez, A. Haberman, and A. Iwasaki. 2009. Differential roles of migratory and resident DCs in T cell priming after mucosal or skin HSV-1 infection. J. Exp. Med. 206: 359-370.
9. + T cell immunodominance in primary and secondary influenza virus infections. J. Exp. Med. 198: 399-410.
10. Byrne, J. A., J. L. Butler, and M. D. Cooper. 1988. Differential activation requirements for virgin and memory T cells. J. Immunol. 141: 3249-3257.
11. + T cells in response to viral infections of the lung and skin. Eur. J. Immunol. 36: 327-335.
12. Zammit, D. J., L. S. Cauley, Q. M. Pham, and L. Lefrançois. 2005. Dendritic cells maximize the memory CD8 T cell response to infection. Immunity 22: 561-570.
13. Luketic, L., J. Delanghe, P. T. Sobol, P. Yang, E. Frotten, K. L. Mossman, J. Gauldie, J. Bramson, and Y. Wan. 2007. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J. Immunol. 179: 5024-5032.
14. Wong, P., and E. G. Pamer. 2003. Feedback regulation of pathogen-specific T cell priming. Immunity 18: 499-511.
15. + T cells in vivo. Proc. Natl. Acad. Sci. USA 103: 147-152.
16. Pol, J. G., L. Zhang, B. W. Bridle, K. B. Stephenson, J. Rességuier, S. Hanson, L. Chen, N. Kazdhan, J. L. Bramson, D. F. Stojdl, et al. 2014. Maraba virus as a potent oncolytic vaccine vector. Mol. Ther. 22: 420-429.
17. + T-cell responses to anticancer vaccines. OncoImmunology 2: e26013.
18. Bridle, B. W., K. B. Stephenson, J. E. Boudreau, S. Koshy, N. Kazdhan, E. Pullenayegum, J. Brunellière, J. L. Bramson, B. D. Lichty, and Y. Wan. 2010. Potentiating cancer immunotherapy using an oncolytic virus. Mol. Ther. 18: 1430-1439.
19. + T cells. J. Exp. Med. 194: 953-966.
20. Khanna, K. M., J. T. McNamara, and L. Lefrançois. 2007. In situ imaging of the endogenous CD8 T cell response to infection. Science 318: 116-120.
21. Dauner, J. G., I. R. Williams, and J. Jacob. 2008. Differential microenvironment localization of effector and memory CD8 T cells. J. Immunol. 180: 291-299.
22. Bridle, B. W., J. E. Boudreau, B. D. Lichty, J. Brunellière, K. Stephenson, S. Koshy, J. L. Bramson, and Y. Wan. 2009. Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus. Mol. Ther. 17: 1814-1821.
23. + T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigenpresenting cells. Blood 117: 1146-1155.
24. Brun, J., D. McManus, C. Lefebvre, K. Hu, T. Falls, H. Atkins, J. C. Bell, J. A. McCart, D. Mahoney, and D. F. Stojdl. 2010. Identification of genetically modified Maraba virus as an oncolytic rhabdovirus. Mol. Ther. 18: 1440-1449.
25. Boudreau, J. E., K. B. Stephenson, F. Wang, A. A. Ashkar, K. L. Mossman, L. L. Lenz, K. L. Rosenthal, J. L. Bramson, B. D. Lichty, and Y. Wan. 2011. IL-15 and type I interferon are required for activation of tumoricidal NK cells by virus-infected dendritic cells. Cancer Res. 71: 2497-2506.
26. + T-cell response following adenovirus vaccination. J. Virol. 77: 13407-13411.
27. + memory T cell subsets. Proc. Natl. Acad. Sci. USA 101: 5610-5615.
28. Ronchese, F., and I. F. Hermans. 2001. Killing of dendritic cells: a life cut short or a purposeful death? J. Exp. Med. 194: F23-F26.
29. Oliver, A. M., F. Martin, G. L. Gartland, R. H. Carter, and J. F. Kearney. 1997. Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses. Eur. J. Immunol. 27: 2366-2374.
30. Potsch, C., D. Vöhringer, and H. Pircher. 1999. Distinct migration patterns of naive and effector CD8 T cells in the spleen: correlation with CCR7 receptor expression and chemokine reactivity. Eur. J. Immunol. 29: 3562-3570.
31. Kitamura, D., J. Roes, R. Kuhn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin m chain gene. Nature 350: 423-426.
32. Ngo, V. N., R. J. Cornall, and J. G. Cyster. 2001. Splenic T zone development is B cell dependent. J. Exp. Med. 194: 1649-1660.
33. + T cells following an acute virus infection. Eur. J. Immunol. 33: 2736-2743.
34. + T cells in vivo. J. Immunol. 154: 5684-5693.
35. + T-cell activation after viral infection. Nature 471: 629-632.
36. Klonowski, K. D., A. L. Marzo, K. J. Williams, S. J. Lee, Q. M. Pham, and L. Lefrançois. 2006. CD8 T cell recall responses are regulated by the tissue tropism of the memory cell and pathogen. J. Immunol. 177: 6738-6746.
37. + T cells enter reactive lymph nodes and kill dendritic cells. Nat. Immunol. 8: 743-752.
38. Jung, Y. W., R. L. Rutishauser, N. S. Joshi, A. M. Haberman, and S. M. Kaech. 2010. Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J. Immunol. 185: 5315-5325.
39. + dendritic cells to the marginal zone of mouse spleen. Proc. Natl. Acad. Sci. USA 106: 1524-1529.
40. + T cells in the peripheral interfollicular region of lymph nodes. Nat. Immunol. 9: 155-165.
41. Junt, T., E. A. Moseman, M. Iannacone, S. Massberg, P. A. Lang, M. Boes, K. Fink, S. E. Henrickson, D. M. Shayakhmetov, N. C. Di Paolo, et al. 2007. Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cells. Nature 450: 110-114.
42. + T-cell recall responses. Blood 121: 2432-2439.