Genetic enhancement of limb defects in a mouse model of Cornelia de Lange syndrome

American Journal of Medical Genetics, Part C: Seminars in Medical Genetics

Volumn 172, Issue 2, 2016, Pages 146-154

  Lopez Burks, Martha E ^a   Santos, Rosaysela ^a   Kawauchi, Shimako ^a   Calof, Anne L ^a   Lander, Arthur D ^a  

^a NONE

Author keywords

bone morphogenetic proteins (BMPs); Hox genes; limb development; Nipped B like (NIPBL) gene; polydactyly; Shh gene

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; FIBROBLAST GROWTH FACTOR; SONIC HEDGEHOG PROTEIN; NIPBL PROTEIN, MOUSE; SHH PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXIAL SKELETAL PHENOTYPE; BMP4 GENE; CONTROLLED STUDY; DE LANGE SYNDROME; DISEASE MODEL; DISEASE SEVERITY; GENE; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC ENHANCEMENT; GENOTYPE; HAPLOINSUFFICIENCY; HOX GENE; HOXD12 GENE; HOXD13 GENE; IN SITU HYBRIDIZATION; LIMB DEFECT; MOUSE; NIPBL GENE; NONHUMAN; PHENOTYPE; POLYDACTYLY; POSTAXIAL POLYDACTYLY; PRIORITY JOURNAL; SHH GENE; SIGNAL TRANSDUCTION; ANIMAL; DEFICIENCY; GENETICS; HOMEOBOX; LIMB MALFORMATION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; DE LANGE SYNDROME; GENES, HOMEOBOX; HAPLOINSUFFICIENCY; HEDGEHOG PROTEINS; LIMB DEFORMITIES, CONGENITAL; MICE; TRANSCRIPTION FACTORS;

EID: 84975074962     PISSN: 15524868     EISSN: 15524876     Source Type: Journal    
DOI: 10.1002/ajmg.c.31491     Document Type: Article

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